Strategies & Technologies Driving Drug Discovery to Market
All Bottled Up
November 8, 2007 5:12 am | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | CommentsDedicated autism researchers are trying to develop animal models that allow for a better understanding of autism and may some day lead to better drugs to the disease. Rodent models of autism, while useful, have their limitations, and finding good models can be a challenge. So how does one find a good model for autism?
Cholesterol-lowering Drug Linked to Sleep Disruptions
November 8, 2007 4:44 am | News | CommentsSimvastatin appears to disrupt sleep patterns of some patients.
Genetic Role in Type 1 Diabetes Uncovered
November 8, 2007 4:21 am | News | CommentsResearchers identify an enzyme thought to be an important instigator of the inner-body conflict that causes Type 1 diabetes.
Blood Pressure Drug Curbs Brain Damage
November 8, 2007 4:08 am | News | CommentsA drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia.
Who Has the Gene?
November 7, 2007 11:36 am | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | CommentsPhenocopy sometimes muddies up the genetic factors of disease risk, but a new way of looking at this issue soon might clean it up.
Beyond Luciferase
November 7, 2007 10:35 am | by Neil Canavan, Contributing Editor | Articles | CommentsAdvances in reporter gene technology aid the investigation of cellular activity. This has led to an increased number of options available to researchers.
Viva in vitro
November 7, 2007 9:43 am | by The Editors of Drug Discovery & Development | Articles | CommentsCell culture technology evolves from Ross Harrison's experiment.
Much-Needed Support
November 7, 2007 9:06 am | by Primary Authors: Kelly Jenkins, Senior Principal Scientist, Pfizer Global Research and Development, La Jolla, Calif.; Gregory Samoil, Galileo Product Manager and Joel Usansky, Watson Product Manager, Thermo Fisher Scientific, Philadelphia, Pa. | Articles | CommentsLIMS may help with obstacles related to medium- and high-throughput ADME screening.
Helping Out
November 7, 2007 8:23 am | by Nathan Collins, Executive Director, SRI International | Articles | CommentsHiring a Contract Research Organization can expedite the drug development process.
Far Eastern Dreams
November 7, 2007 7:05 am | by K. John Morrow, Jr., PhD | Articles | CommentsAsian lands experiencing up-and-downs in the biosciences continue to push forward to compete with the EU and US.
Smaller Portions
November 7, 2007 6:08 am | by Gary Herman, MD, Executive Director of Experimental Medicine, Merck & Co., Inc. | Articles | CommentsMerck’s food intake model aids high-throughput screening of anti-obesity drugs.
PDUFA Action Begins
November 7, 2007 4:31 am | by Ted Agres, Contributing Editor | Articles | CommentsDrug manufacturers, law-makers, and consumer groups all found much to praise in the passage of the Food and Drug Administration Amendments Act of 2007 (HR 3580), which President Bush signed into law in late September. But much will depend on how the FDA implements the roughly 200 provisions contained in the 156-page piece of legislation.
Going with the Flow
November 6, 2007 11:29 am | by Mike May, Contributing Editor | Articles | CommentsWith all of the cells in organisms, and cells just wandering around in the environment, scientists always seek new ways to sort them. The results unveil basic and applied value.
Network Formed to Tackle Cardiac Safety Challenge
November 6, 2007 10:54 am | News | CommentsA group of companies that specialize in cardiac safety testing have joined forces to create a comprehensive and technologically advanced solution for determining how drugs affect the heart.
Metastatix Granted Investigational New Drug Application for MSX-122
November 6, 2007 10:44 am | News | CommentsMetastatix announced that the US Food and Drug Administration has accepted its Investigational New Drug application for MSX-122.
