Strategies & Technologies Driving Drug Discovery to Market
Mapping Gene Expression for Growth
October 4, 2007 10:11 am | by Juan Medrano, PhD, Charles Farber, PhD, and Mark Springer | Articles | CommentsUsing an expression quantitative trait loci approach could identify genetic variations affecting growth and obesity in mice, and may have applications in humans.
In-house Kinase Profiling
October 4, 2007 10:06 am | Product Releases | CommentsCaliper Life Sciences launched the Caliper LabChip EZ Reader series for in-house kinase profiling. The series includes the new EZ Reader II system, a bench-top reader to use for real-time kinetic analysis with push-button operation, and the EZ Reader system.
Open Source Bioinformatics
October 4, 2007 9:28 am | by Neil Canavan, Contributing Editor | Articles | CommentsIn an effort to fight back against the stifling effect of scientific knowledge being kept under wraps, researchers are creating an open-source community that allows them to advance science by sharing data.
Fluorescent Proteins and Gene Expression
October 4, 2007 7:51 am | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | CommentsFluorescent proteins have been available for several years, but new instruments that measure fluorescence have allowed researchers to use such proteins to study gene expression.
DNA Microarrays Tackle Infectious Disease
October 4, 2007 7:03 am | Articles | CommentsThe genetic sequencing of many infectious agents has allowed researchers to use DNA microarrays to study disease. Scientists are exploring a number of areas, including host-pathogen interactions and DNA-protein interactions.
Mapping Avian Flu Mutations
October 4, 2007 6:49 am | by Catherine Shaffer, Contributing Editor | Articles | CommentsScientists are using a variety of tools and techniques to determine how the H5N1 influenza virus is mutating.
Government Fosters Malaysian Biotech
October 3, 2007 12:52 pm | by Patrick McGee, Senior Editor | Articles | CommentsMalaysia is developing centers of excellence and fighting brain drain as it works to establish itself as a biotech hotbed.
Protein Microarrays in Cancer Research
October 3, 2007 12:30 pm | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | CommentsThe collaborative efforts of multidisciplinary scientists are pushing the boundaries of cancer research.
Protein Initiative Spurs Innovation
October 3, 2007 12:10 pm | by Neil Canavan, Contributing Editor | Articles | CommentsThe Protein Structure Initiative is the largest, most ambitious effort of its kind. Its success depends on imagination and innovation.
Array of Challenges in Proteomics Research
October 3, 2007 11:30 am | by James Netterwald, PhD, MT(ASCP), Senior Editor | Articles | CommentsThe full potential of protein array technology is within reach, but there are still hurdles to be overcome before it is completely realized.
Finding an RNA Needle in a Small Haystack
October 3, 2007 10:41 am | by James Netterwald, PhD, MT(ASCP), Senior Editor | Articles | CommentsRNA is difficult to isolate from any sample, but is especially difficult when its cellular source is limited. Researchers say newer RNA isolation methods are needed to overcome these challenges.
On the Right Path
October 3, 2007 10:28 am | by James Netterwald, PhD, MT(ASCP), Senior Editor | Articles | CommentsA new paradigm in biological research is taking shape, and now systems biologists have the money needed to put them on the road to solving key biological problems.
SNP It in the Bud
October 3, 2007 10:09 am | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | CommentsResearchers are working to sort out genetic markers for human diseases using single nucleotide polymorphisms (SNPs).
Piling up Proteins to Improve Prognosis
October 3, 2007 9:02 am | by Mike May, PhD, Contributing Editor | Articles | CommentsFinding new protein biomarkers and using them in combinations promises earlier detection of a variety of diseases, from Alzheimer’s to cancer, but identifying these biomarkers depends on negotiating difficult technological challenges.
'Omics' Shine New Light on Neuroscience
October 3, 2007 8:53 am | by James Netterwald, PhD, MT(ASCP), Senior Editor | Articles | CommentsAfter some delay, skeptical neuroscientists realize the awesome power of genomic and proteomic tools for solving the mysteries of mental illness.
