New tools are continually being introduced to meet proteomics researcher's needs.
Applied Biosystems’ SOLiD platform system for ultra high-throughput DNA analysis is based on sequencing by oligonucleotide ligation and detection.
A plethora of device configurations and membranes make it difficult to determine a method for a specific sample. Choosing the appropriate membrane to fit the macromolecule involves an understanding of how ultrafiltration works.
Globular proteins fold very quickly, but little is known about how they do it. Improvements in computing power and novel approaches are whittling away at the mysteries of protein movement.
The hearing precision of barn owls is helping University of Oregon researchers fine tune diagnosis of a variety of problems rooted in the human brain.
Novel approaches in miniaturization, integration, and automation will solve the most challenging proteins. These tools can be used to understand protein-protein and protein-DNA interactions in order to target specific diseases. The Accelerated Technologies Center for Gene to 3D Structure is one of six specialized
Researchers have identified three gene variants in the DNA of 486 people infected with HIV that appear to have helped some of the patients fight off the virus and delay the onset of AIDS.
The International Multiple Sclerosis Genetics Consortium (IMSGC) identified two new genetic variations associated with multiple sclerosis (MS), completing the largest replicated whole genome scan for MS to date.
Research on the DNA of 15 mouse strains is expected to help scientists determine the genes related to susceptibility to environmental disease.
Bioterror threats are among the gravest we face. But dedicated scientists and engineers across the nation are working tirelessly at harnessing the power of omics technologies to minimize those threats, and their efforts are already beginning to pay off.
Tanuja Koppal, PhDEditor in Chief With the birth of genomics and later proteomics, scientists started examining genes and proteins not as random entities that played a role in
In the shadow of rapid microcapillary biochip analysis methods, slab-gel SDS-PAGE still affords researchers high versatility and control. This electrophoresis method better preserves sample integrity and supports coupled methods and varied dyes.
Research is accelerating many steps in the protein crystallography process, but bottlenecks can still be a challenge. Robots that can handle crystals and improved tools for diffraction data should help speed output.
These excerpts from a recent Webcast on quantitative polymerase chain reaction for gene expression analysis involve experts from industry and academia discussing their experiences with, and data gained from, the method.
Molecular complications really increase after translation of DNA into proteins, when the proteins acquire branched carbohydrate structures. Multidisciplinary consortia are forming to begin deciphering this glycomic role.