Strategies & Technologies Driving Drug Discovery to Market
Proteomics Milestones
October 5, 2007 11:09 am | by Tanuja Koppal, PhD, Editor-in-Chief | Articles | CommentsNew tools are continually being introduced to meet proteomics researcher's needs.
DNA Analysis
October 5, 2007 11:02 am | Product Releases | CommentsApplied Biosystems’ SOLiD platform system for ultra high-throughput DNA analysis is based on sequencing by oligonucleotide ligation and detection.
Ultrafiltration: Trends in Sample Prep
October 5, 2007 11:02 am | by Mark Kavonian and Elena Chernokalskaya, PhD, Millipore Corp. | Articles | CommentsA plethora of device configurations and membranes make it difficult to determine a method for a specific sample. Choosing the appropriate membrane to fit the macromolecule involves an understanding of how ultrafiltration works.
Computer Tutoring for Protein Origami
October 5, 2007 10:53 am | by Catherine Shaffer, Contributing Editor | Articles | CommentsGlobular proteins fold very quickly, but little is known about how they do it. Improvements in computing power and novel approaches are whittling away at the mysteries of protein movement.
Barn Owls Hearing Skills Could Help Humans
October 5, 2007 10:42 am | News | CommentsThe hearing precision of barn owls is helping University of Oregon researchers fine tune diagnosis of a variety of problems rooted in the human brain.
Integrating New Technologies for Solving Structures
October 5, 2007 10:34 am | by Elizabeth Tolchin, Contributing Editor | Articles | CommentsNovel approaches in miniaturization, integration, and automation will solve the most challenging proteins. These tools can be used to understand protein-protein and protein-DNA interactions in order to target specific diseases. The Accelerated Technologies Center for Gene to 3D Structure is one of six specialized
Targets for HIV Vaccine Found
October 5, 2007 10:28 am | News | CommentsResearchers have identified three gene variants in the DNA of 486 people infected with HIV that appear to have helped some of the patients fight off the virus and delay the onset of AIDS.
New Genetic Risk Factors for MS Identified
October 5, 2007 10:22 am | News | CommentsThe International Multiple Sclerosis Genetics Consortium (IMSGC) identified two new genetic variations associated with multiple sclerosis (MS), completing the largest replicated whole genome scan for MS to date.
Mice Help Identify Environmental Disease Causes
October 5, 2007 10:13 am | News | CommentsResearch on the DNA of 15 mouse strains is expected to help scientists determine the genes related to susceptibility to environmental disease.
Bioterrorists Beware: Biotech Is Not Your Friend
October 5, 2007 9:40 am | by John Schneider, Contributing Editor | Articles | CommentsBioterror threats are among the gravest we face. But dedicated scientists and engineers across the nation are working tirelessly at harnessing the power of omics technologies to minimize those threats, and their efforts are already beginning to pay off.
Scientific Brand Marketing
October 5, 2007 8:20 am | Articles | CommentsTanuja Koppal, PhDEditor in Chief With the birth of genomics and later proteomics, scientists started examining genes and proteins not as random entities that played a role in
Protein Electrophoresis: The Benchside View
October 5, 2007 8:08 am | by Louise Garone, PhD, Contributing Editor | Articles | CommentsIn the shadow of rapid microcapillary biochip analysis methods, slab-gel SDS-PAGE still affords researchers high versatility and control. This electrophoresis method better preserves sample integrity and supports coupled methods and varied dyes.
Automation Lends Crystallographers a Hand
October 5, 2007 8:01 am | by Alisa Woods, PhD , Contributing Editor | Articles | CommentsResearch is accelerating many steps in the protein crystallography process, but bottlenecks can still be a challenge. Robots that can handle crystals and improved tools for diffraction data should help speed output.
How Reliable is Your qPCR Data?
October 5, 2007 7:42 am | Articles | CommentsThese excerpts from a recent Webcast on quantitative polymerase chain reaction for gene expression analysis involve experts from industry and academia discussing their experiences with, and data gained from, the method.
Counting Carbs: Glycomics Gears Up
October 5, 2007 7:00 am | by Alan Dove, PhD, Contributing Editor | Articles | CommentsMolecular complications really increase after translation of DNA into proteins, when the proteins acquire branched carbohydrate structures. Multidisciplinary consortia are forming to begin deciphering this glycomic role.
