Strategies & Technologies Driving Drug Discovery to Market
Closing the Gap
October 4, 2007 12:57 pm | Articles | CommentsPatrick McGeeSenior Editor Last month, the Muscular Dystrophy Association announced the first US human gene therapy trial for Duchenne muscular dystrophy, which will take place at Columbus Children's
Integrating Transcriptomics and Proteomics
October 4, 2007 12:34 pm | by Eric Chan, Rosetta Biosoftware | Articles | CommentsExpression analyses and molecular biological studies contribute to a systems-level understanding of host response, and new analytical software tools can help.
Collaboration Can Advance Pharmacogenomics
October 4, 2007 12:20 pm | by Bill Schu, Contributing Editor | Articles | CommentsAdvances in genomics, molecular biology, and bioinformatics are converging to form an environment rich for pharmacogenomic discoveries. But who will till the soil?
Mass Spectrometry Targeting New Areas
October 4, 2007 11:26 am | by Mark Terry, Contributing Editor | Articles | CommentsDevelopments in any technological field tend to be driven by need, computing power, and often, new discoveries. Mass spectrometry researchers are constantly working to develop higher sensitivity or new applications for their technology.By Mark Terry Although mass spectrometry can safely
Luciferase Assay Reagents
October 4, 2007 11:13 am | Product Releases | CommentsPromega offers the ONE-Glo luciferase assay reagent, exhibiting reproducibility with fewer false positives while generating an extended bright light signal.
Cytotoxicity Profiling Assay Kit
October 4, 2007 11:05 am | Product Releases | CommentsMillipore’s CellCiphr cytotoxicity profiling assay kit, developed in collaboration with Cellumen, detects drug-induced hepatotoxicity.
Political Controversy Inspires Stem Cell Debate
October 4, 2007 10:51 am | by Phillip Jones, Contributing Editor | Articles | CommentsScientists have gotten around objections to human stem cell research by reworking therapeutic cloning and mining a new source of adult stem cells, but a number of challenges remain.
Fragment Screening
October 4, 2007 10:40 am | Product Releases | CommentsACD/IntelliXtract from Advanced Chemistry Development allows researchers to identifying and elucidate the structures of related compounds by LC/MS with related fragment screening.
Assay Development
October 4, 2007 10:35 am | Product Releases | CommentsPerkinElmer launched a comprehensive assay development service for high-performance, highly sensitive assays.
High Content Screening
October 4, 2007 10:23 am | Product Releases | CommentsThermo Fisher Scientific now offers a series of software and hardware modules to enhance the functionality of its HCS HCA platform. These include the introduction of the Thermo Scientific HCSExplorer informatics software, new functionality of its BioApplications line of image.
Mapping Gene Expression for Growth
October 4, 2007 10:11 am | by Juan Medrano, PhD, Charles Farber, PhD, and Mark Springer | Articles | CommentsUsing an expression quantitative trait loci approach could identify genetic variations affecting growth and obesity in mice, and may have applications in humans.
In-house Kinase Profiling
October 4, 2007 10:06 am | Product Releases | CommentsCaliper Life Sciences launched the Caliper LabChip EZ Reader series for in-house kinase profiling. The series includes the new EZ Reader II system, a bench-top reader to use for real-time kinetic analysis with push-button operation, and the EZ Reader system.
Open Source Bioinformatics
October 4, 2007 9:28 am | by Neil Canavan, Contributing Editor | Articles | CommentsIn an effort to fight back against the stifling effect of scientific knowledge being kept under wraps, researchers are creating an open-source community that allows them to advance science by sharing data.
Fluorescent Proteins and Gene Expression
October 4, 2007 7:51 am | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | CommentsFluorescent proteins have been available for several years, but new instruments that measure fluorescence have allowed researchers to use such proteins to study gene expression.
DNA Microarrays Tackle Infectious Disease
October 4, 2007 7:03 am | Articles | CommentsThe genetic sequencing of many infectious agents has allowed researchers to use DNA microarrays to study disease. Scientists are exploring a number of areas, including host-pathogen interactions and DNA-protein interactions.
