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The Cystic Fibrosis Foundation's Controversial New Cash

November 26, 2014 12:00 pm | by Ryan Bushey, Associate Editor | Articles | Comments

Concerns have been raised relating to a lucrative investment the Cystic Fibrosis Foundation made in a biotechnology company. Read more...                    

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DDD Update

Daily news and top headlines for drug research professionals

Big Data to Make Big Difference in Childhood Cancer Treatment

November 26, 2014 12:00 pm | News | Comments

Research crunching vast amounts of data on childhood cancer to better tailor treatment is one step closer to assisting clinicians through a collaboration that boasts a virtual pipeline that visualizes large quantities of patient data to help hospital clinicians better diagnose and treat childhood cancer patients.

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Chinese-Built Ebola Center Dedicated in Liberia

November 26, 2014 12:00 pm | by Jonathan Paye-Layleh and Clarence Roy-Macaulay, Associated Press | News | Comments

China, one of the first countries to send aid to battle Ebola in West Africa, ramped up the assistance significantly Tuesday by opening a 100-bed treatment center in Liberia as rows of uniformed Chinese army medics stood at attention.      

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First-in-Human Study of Antibody for AML Kicks Off

November 26, 2014 12:00 pm | News | Comments

Oxford BioTherapeutics and Berlin Chemie/Menarini Biotech/Menarini Ricerche announced that they have initiated the first-in-human clinical study of OBT357 (MEN1112), a novel enhanced antibody for the treatment of acute myeloid leukemia (AML). Read more...

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A Hybrid Vehicle That Delivers DNA

November 26, 2014 12:00 pm | News | Comments

A new hybrid vehicle is under development. Its performance isn’t measured by the distance it travels, but rather the delivery of its cargo: vaccines that contain genetically engineered DNA to fight HIV, cancer, influenza and other maladies. Read more...

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A Reason to be Thankful: Turkeys May be Lifesavers

November 26, 2014 12:00 pm | News | Comments

While the turkey you eat on Thursday will bring your stomach happiness and could probably kick-start an afternoon nap, it may also save your life one day. Read more...                        

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C3BS Nominates Investigators for Clinical Trial of Heart Failure Treatment

November 26, 2014 9:56 am | News | Comments

Cardio3 BioSciences announces the appointment of its three Co-Principal Investigators for the study of its heart failure treatment. Read more...                   

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Public Health Interventions Needed to Tackle 'Lifestyle' Diseases

November 26, 2014 9:31 am | News | Comments

Interventions such as the smoking ban help to break habits instead of relying on individuals to make the right decision for their health. Read more...                   

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Valeant Receives FDA Approval for Acne Treatment

November 26, 2014 8:58 am | News | Comments

Valeant Pharmaceuticals announced it has received FDA approval of a gel that can treat acne vulgaris. Read more...                         

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Transposagen, Janssen to Collaborate on CAR-T Therapies

November 25, 2014 1:46 pm | News | Comments

Transposagen Biopharmaceuticals, Inc., a private biotechnology company headquartered in Lexington, KY, announced they have entered into a research collaboration and worldwide license agreement with Janssen Biotech, Inc. to develop allogeneic Chimeric Antigen Receptor T-cells (CAR-T). Read more...

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Powdered Measles Vaccine Found Safe in Early Clinical Trials

November 25, 2014 12:51 pm | News | Comments

A measles vaccine made of fine dry powder and delivered with a puff of air triggered no adverse side effects in early human testing and it is likely effective. Read more...                             

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Drugs to Block Angiogenesis Could Provide New TB Treatment

November 25, 2014 12:36 pm | News | Comments

The body responds to tuberculosis infection by locking the bacterial offenders into tiny clusters of immune cells called granulomas, which are a hallmark of the disease. This containment strategy succeeds at first, but eventually the bacteria manage to break out of these intercellular jails and spread throughout the body. Read more...

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Janssen Submits NDA for STS Treatment

November 25, 2014 12:29 pm | News | Comments

Janssen Research & Development, LLC (Janssen) has submitted a New Drug Application (NDA) for Yondelis (trabectedin) to the U.S. Food and Drug Administration (FDA) for the treatment of patients with advanced soft tissue sarcoma (STS), including liposarcoma and leiomyosarcoma subtypes, who have received prior chemotherapy including an anthracycline. Read more...

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How Environment Contributes to Human Diseases

November 25, 2014 12:22 pm | News | Comments

Using a new imaging technique, National Institutes of Health researchers have found that the biological machinery that builds DNA can insert molecules into the DNA strand that are damaged as a result of environmental exposures. Read more...                

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Protein Key to Development of Blood Stem Cells Identified

November 25, 2014 12:13 pm | by Peter Bracke, UCLA | News | Comments

Understanding the self-replication mechanisms is critical for improving stem cell therapies for blood-related diseases and cancers. Read more...                                           

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$1B Alliance Between Menarini, Oxford BioTherapeutics for Enhanced AML Treatment

November 25, 2014 10:04 am | News | Comments

This is the first of five development programs between the two companies to enter the clinic in a $1 billion strategic oncology alliance. Read more...                   

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