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DDD Update

Daily news and top headlines for drug research professionals

Impact of Label-Free Cell-Based Assays and the Holistic Calorimetry Approach

April 17, 2015 10:23 am | by Magnus Jansson, Ph.D., CSO, SymCel Sverige AB | Articles | Comments

New, innovative technology solves challenges in antibiotic resistance and the drug development cycle. Read more...

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Electronic Micropump Could Deliver Treatment to Specific Brain Region

April 17, 2015 10:13 am | by Stephanie Guzowski, Editor | News | Comments

There is an exactness that must be taken into account when treating neurological disorders. In treating epilepsy, for example, a condition in which nerve cell activity in the brain is disturbed, causing seizures, a drug needs to be delivered directly to a specific brain region—but without negatively affecting healthy brain regions. Read more...

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Synthetic Drugs: Evidence That They Can Cause Cancer

April 17, 2015 8:19 am | by Medical University of Vienna | News | Comments

Synthetic cannabinoids are difficult to identify chemically and the possible unwanted toxic effects that can occur following their consumption have so far barely been investigated. Read more...

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Actelion Advances Clinical Development of its Specialty Immunology Pipeline Compounds

April 17, 2015 8:12 am | News | Comments

Actelion announced that it is accelerating its clinical development efforts in the field of immunological disorders. Read more...

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Gene Variant Linked to Cancer

April 17, 2015 8:11 am | by Washington University in St. Louis | News | Comments

Smokers with a specific genetic variation are more likely to keep smoking longer than those who don’t have the gene variant. Read more...

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Scientists Discover Protein That Boosts Immunity to Viruses and Cancer

April 17, 2015 8:10 am | by Imperial College London | News | Comments

Scientists have discovered a protein that plays a central role in promoting immunity to viruses and cancer, opening the door to new therapies. Read more...

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Evidence Grows that Melanoma Drugs Benefit Some Lung Cancer Patients

April 17, 2015 8:09 am | by European Society for Medical Oncology | News | Comments

A subset of lung cancer patients can derive important clinical benefits from drugs that are more commonly used to treat melanoma. Read more...

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Pfizer Breast Cancer Drug Shows Promising Results

April 16, 2015 2:19 pm | by Stephanie Guzowski, Editor | News | Comments

Pfizer said on Wednesday a late-stage trial of its treatment for advanced breast cancer, Ibrance, was stopped early after it met its primary goal of delaying disease progression. Read more...

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Identifying Molecular Mechanism That Makes Malaria Parasites Drug-Resistant

April 16, 2015 12:57 pm | by University of Notre Dame | News | Comments

University of Notre Dame researchers led an international team to identify a molecular mechanism responsible for making malaria parasites resistant to artemisinins, the leading class of antimalarial drugs. Read more...

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How PBPK Models Advance the Understanding of Therapeutic Antibodies

April 16, 2015 10:40 am | by Suzanne K. Minton, Ph.D., Scientific Content Specialist, Certara | Articles | Comments

Monoclonal antibodies (mAbs) are large Y-shaped proteins that are produced by immune cells to defend the body against pathogens. A hallmark of antibodies is their ability to specifically bind to epitopes, or the parts of the antigen that the immune system recognizes, on their molecular targets, which has been harnessed by drug companies to develop treatments for certain cancers and autoimmune diseases. Read more...

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Abbot Receives FDA Clearance for New Blood Glucose Meter

April 16, 2015 10:38 am | News | Comments

The cost of insurance premiums and employee medical claims continues to rise in the United States, which is especially challenging for people living with chronic conditions such as diabetes. Read more...

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Abbvie's Chronic Hepatitis C Treatment Granted Priority Review in Japan

April 16, 2015 10:31 am | News | Comments

AbbVie today announced that the Japanese Ministry of Health, Labour and Welfare (MHLW) has granted priority review for its investigational, two direct-acting antiviral treatment of ombitasvir/paritaprevir/ritonavir. Read more...

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FDA Approves New Type of Heart Failure Drug From Amgen

April 16, 2015 10:12 am | by Linda Johnson, AP Business Writer | News | Comments

Patients with chronic heart failure, a disabling, deadly disease that worsens as the heart gradually pumps less efficiently, are getting a much-needed new option with U.S. approval Wednesday of a novel drug from Amgen Inc. Read more...

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Botox Makes Unnerving Journey into Our Nervous System

April 16, 2015 8:53 am | by University of Queensland | News | Comments

New research might bring a frown to even the most heavily botoxed faces, with scientists finding how some of the potent toxin used for cosmetic surgery escapes into the central nervous system. Read more...

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