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DDD Update

Daily news and top headlines for drug research professionals

Abivax to Commercialize Vaccines in Asia, Latin America

November 13, 2014 10:05 am | News | Comments

Abivax, a leading European, clinical stage biopharmaceutical company developing and commercializing anti-viral compounds and human vaccines, announced that it has signed an agreement with The Finlay Institute, Havana, Cuba, that will allow it to commercialize vaccines against typhoid, meningococcus, and leptospirosis, in Asian and Latin American markets. Read more...

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AstraZeneca, Isis Pharmaceuticals to Co-Develop Targeted Delivery

November 13, 2014 9:57 am | News | Comments

Isis Pharmaceuticals Inc. and AstraZeneca announced a strategic alliance to discover and develop novel delivery methods for antisense oligonucleotides. The new delivery approaches seek to target the desired tissue more effectively. Read more...                   

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Gene Study Boosts Interest in Heart Drug Zetia

November 13, 2014 9:50 am | by Marilynn Marchione, AP Chief Medical Writer - Associated Press | News | Comments

Scientists have discovered gene mutations that give people naturally lower cholesterol levels and cut their risk of heart disease in half. That discovery may have a big implication. Read more...

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Ebola Drug Testing Sparks Ethics Debate

November 13, 2014 9:36 am | by Matthew Perrone, AP Health Writer - Associated Press | News | Comments

Health officials are scrambling to begin human testing of a handful of experimental drugs for Ebola. But the effort has sparked an ethical debate over how to study unproven medicines amid an outbreak that has killed nearly 5,000. Read more...

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Improved Survival in Women with HER2 Negative Breast Cancer

November 13, 2014 9:22 am | News | Comments

The results from a pooled analysis of two Phase 3 Halaven (eribulin) trials are published in Breast Cancer Research and Treatment. Findings from the pooled analysis show that eribulin improves overall survival in women compared to control. Read more...

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Measuring PD-L1 Expression in CTCs in Lung Cancer Patients

November 12, 2014 2:34 pm | News | Comments

Epic Sciences will present an analysis of PD-L1 protein expression on circulating tumor cells (CTCs) from non-small cell lung cancer (NSCLC) patients.  Read more...                                               

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Next-Gen Melanoma Drug Excels in Lab Tests

November 12, 2014 2:16 pm | by Garth Sundem, University of Colorado | News | Comments

A University of Colorado Cancer Center study published online in the journal Molecular Cancer Therapeutics reports anti-cancer activity in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733, a small molecule inhibitor of MEK1/2.  Read more...

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The Odd Ouster of Sanofi's Former CEO

November 12, 2014 2:16 pm | by Ryan Bushey, Associate Editor | Articles | Comments

This high-flying pharma executive had his career derailed for a variety of surprising factors. Read more...                          

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Altered Milk Protein Can Deliver AIDS Drug to Infants

November 12, 2014 1:57 pm | by Jeff Mulhollem, Penn State | News | Comments

A novel method of altering a protein in milk to bind with an antiretroviral drug promises to greatly improve treatment for infants and young children suffering from HIV/AIDS, according to a researcher in Penn State's College of Agricultural Sciences. Read more...

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Targets, Tests May Develop Treatments for Memory Disorders

November 12, 2014 1:38 pm | by Scripps Research Institute | News | Comments

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a number of new therapeutic targets for memory disorders and have developed a new screening test to uncover compounds that may one day work against those disorders. Read more...

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Blood Test Could Reduce Antibiotic Use

November 12, 2014 12:20 pm | News | Comments

The key component of this test is a new blood biomarker test that indicates whether bacteria is the cause of a patient’s lung infection. Read more...                   

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Abbvie's Hep C Therapy Shows Strong Cure Rate

November 12, 2014 10:37 am | News | Comments

AbbVie announced positive results for its therapy for chronic hepatitis C patients and liver transplant recipients. Read more...                     

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Enterome, AbbVie to Collaborate on Treatments for Crohn's Disease

November 12, 2014 10:16 am | News | Comments

Enterome Bioscience and AbbVie will work together to develop solutions for the treatment of Crohn's disease. Read more...                       

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Amgen and AstraZeneca's Psoriasis Drug Receives Positive Results

November 12, 2014 9:57 am | News | Comments

This drug is intended for patients with moderate-to-severe plaque psoriasis. Read more...                             

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Researchers Help China Predict Dengue Fever Outbreaks

November 12, 2014 9:34 am | News | Comments

Researchers have found the habit of Googling for an online diagnosis before visiting the doctor can be a powerful predictor of infectious diseases outbreaks.                  

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