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DDD Update

Daily news and top headlines for drug research professionals

Study Sheds New Light on Asthma, COPD

March 19, 2015 1:08 pm | by Julia Evangelou Strait, Washington University in St. Louis | News | Comments

In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production. Read more...

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Targeted Drug Doubles Progression Free Survival in Hodgkin Lymphoma

March 19, 2015 12:57 pm | News | Comments

A phase 3 trial of brentuximab vedotin (BV), the first new drug for Hodgkin lymphoma in over 30 years, shows that adults with hard-to-treat Hodgkin lymphoma given BV immediately after stem cell transplant survived without the disease progressing for twice as long as those given placebo (43 months vs 24 months). Read more...

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Capturing the Living Picture of Cancer: Proteomic Testing in the Clinical Lab

March 19, 2015 12:46 pm | by Richard Hockett, M.D., Chief Medical Officer at Biodesix, a molecular diagnostics company | Articles | Comments

If genetic sequencing provides the script of life, then proteomics is the live video capturing biology in action. Proteomics moves beyond the static information provided by genomics and tells the story in real-time of proteins, which result from the individual genes within a cell. Read more...

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AbbVie Seeks $30M Expansion of Plant in Puerto Rico

March 19, 2015 9:30 am | by The Associated Press | News | Comments

Government officials say in a statement issued Wednesday that the Chicago-based company will expand its facilities in the north coastal town of Barceloneta. Read more...

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Sierra Leone Plans Another Shutdown to Stop Ebola's Spread

March 19, 2015 9:26 am | by Clarence Roy-Macaulay, Associated Press | News | Comments

Sierra Leone is planning another three-day, countrywide shutdown later this month to ferret out Ebola cases, remind people how to protect themselves from the disease and control its transmission. Read more...

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Hypertension Drugs Improve Corticosteroid-based Skin Treatments

March 19, 2015 9:24 am | by Inserm | News | Comments

Corticosteroid-based dermatological creams are indicated for the symptomatic treatment of inflammatory skin conditions. Read more...

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Global Type 1 Diabetes Treatment Market Value Doubling to $13.6 Billion by 2023

March 19, 2015 9:16 am | by Valentina Gburcik, Ph.D., GlobalData’s Therapy Director of Cardiovascular and Metabolic Disorders | News | Comments

The global treatment market for Type 1 Diabetes (T1D) will expand from $6.6 billion in 2013 to an estimated $13.6 billion by 2023, representing a Compound Annual Growth Rate (CAGR) of 7.6 percent. Read more...

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Antibiotic Nanoparticles Attack Respiratory Infection

March 19, 2015 9:11 am | by Helmholtz Centre for Infection Research | News | Comments

Treating respiratory disease is often difficult because drugs have to cross biological barriers such as respiratory tissue and mucosa, and must therefore be given in large quantities in order for an effective amount to reach the target. Read more...

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Novartis Gains EU Approval for Rare Blood Cancer Drug

March 19, 2015 9:06 am | News | Comments

This medication is the first targeted treatment approved by the European Commission for these patients. Read more...

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AstraZeneca’s COPD Drug: Promising Phase 3 Study

March 18, 2015 1:16 pm | by Stephanie Guzowski, Editor | News | Comments

AstraZenca’s experimental drug, PT003, for chronic obstructive pulmonary disease (COPD) has had successful results in two final-stage Phase 3 trials (24-week studies PINNACLE 1 and PINNACLE 2). Read more...

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Are Antipsychotic Drugs more Dangerous to Dementia Patients Than We Think?

March 18, 2015 11:56 am | by University of Michigan | News | Comments

Drugs aimed at quelling the behavior problems of dementia patients may also hasten their deaths more than previously realized, a new study finds. Read more..

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3-D Protein Snapshot Highlights Potential Drug Target for Breast Cancer

March 18, 2015 11:18 am | by University of Vermont | News | Comments

The genome of a cell is under constant attack, suffering DNA damage that requires an army of repair mechanisms to keep the cell healthy and alive. Understanding the behavior of the enzymes defending these assaults helps determine how - and where - cancer gets its foothold and flourishes. Read more...

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Study Suggests Precision Medicine for Adrenal Cancer

March 18, 2015 10:57 am | by University of Michigan | News | Comments

Despite overall lack of success, small subset of patients responds to investigational drug. Read more...

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Breast Biopsy Accuracy is Questioned in Experimental Study

March 18, 2015 10:41 am | by By Lindsey Tanner, AP Medical Writer | News | Comments

Here's another reason for getting a second medical opinion: Biopsy specialists frequently misdiagnose breast tissue, potentially leading to too-aggressive treatment for some women and under-treatment for others, a study suggests. Read more...

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Where is the Money in Biosimilars?

March 18, 2015 9:11 am | by Daniel N. Galbraith, Ph.D., BioOutsource Ltd | Articles | Comments

In the past 10 years biosimilars have held strong in the biologics industry’s headlines. These products were once thought impossible to approve in regulated markets because the sheer complexity of producing these large, complex proteins can result in “robustness” issues. Read more...

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