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Promising Malaria and Dengue Vaccines Will Not Defeat Diseases

May 20, 2015 | by Christopher J. Pace, Ph.D., GlobalData Managing Analyst, Infectious Diseases | Comments

Some industry pundits rightfully question the modest protective efficacies of CYD-TDV and RTS,S/AS01. Read more...

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Several Blockbuster Drugs to Arrive This Year as Prescription Prices Rise

February 3, 2016 10:43 am | by Ryan Bushey, Associate Editor | Comments

Liver disease and HIV therapies are cited as the leading treatments. Read more...

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Inhibiting Apolipoprotein C-III Production to Reduce Triglyceride Levels in Patients With FCS

February 3, 2016 8:55 am | by Rosanne M. Crooke, Ph.D., Ionis Pharmaceuticals | Comments

In recent years research has presented important new findings regarding the mechanism of action of familial chylomicronemia syndrome (FCS), a rare genetic disease that affects production or functionality of lipoprotein lipase (LPL), an enzyme necessary for the metabolism of triglycerides (TG). Read more...

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Drug Discovery for Rare Diseases

February 1, 2016 10:15 am | by Samuel Falsetti, PhD, Partner, Director of Clinical Strategy, Cambridge BioMarketing | Comments

Q&A on the challenges, approaches and best practices for discovering drugs for the rare disease market. Read more...

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Unifying In Silico and Physical Experimentation to Radically Accelerate Innovation

January 25, 2016 9:27 am | by Adrian Stevens and Tim Moran, of Dassault Systèmes BIOVIA | Comments

Predictive data models and information about previous experiments can help scientists recognize which choices are likely to accelerate progress and which will lead to dead ends. The goal is to achieve better insights sooner by making data available throughout the entire workflow. Read more...

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Accelerating Drug Discovery Through Data Analysis

January 19, 2016 10:00 am | by Ryan Bushey, Associate Editor | Comments

Clinical research can be a risky and laborious process, but this startup could solve that problem. Read more...

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Cost Squeeze Conundrum: Pay Up or Move Along?

January 14, 2016 8:51 am | by Roger Humphrey, Executive Managing Director, JLL Life Sciences | Comments

‘Invest in the best’ sounds good in theory—but it’s becoming a costly challenge for biopharmaceutical companies expanding their R&D operations in the United States. Large, mid-sized and small companies are all facing a growing cost squeeze for labor and laboratories near leading centers for research and innovation, while efficiency continues to be a major operational driver. It’s a challenging combination. Read more...

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New Proteomics Tools to Open Up Drug Discovery

January 6, 2016 9:15 am | by Dr. Paul Ko Ferrigno, Chief Scientific Officer, and Dr. Jane McLeod, of Avacta Life Sciences | Comments

In the current genomic era of very accurate DNA analyses by in situ hybridization, DNA chip analyses, and deep sequencing, it is often assumed that antibodies have an analogous ability to identify molecular targets accurately. Nothing could be further from the truth. Read more...

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'Moneyball' Statistician Joins Scripps Health Data Team

January 6, 2016 8:52 am | by Greg Watry, Digital Reporter | Comments

Paul DePodesta, the assistant general manager for the Oakland Athletics between 1998 and 2004, is bringing his statistical prowess to Scripps Translational Science Institute. Read more...

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SSc Treatments to Have Modest Growth Despite Unmet Research Needs

January 6, 2016 8:28 am | by Ryan Bushey, Associate Editor | Comments

Treatments for systemic sclerosis differ based on patient needs since the symptoms also vary. Read more...

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Hemophilia Treatments Expected to Have Marginal Growth by 2024

January 5, 2016 8:36 am | by Ryan Bushey, Associate Editor | Comments

The market for both hemophilia A and B recombinant therapies is expected to see narrow growth by 2024. Read more...

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Rapid Expansion Predicted for Gastric Cancer Treatment Market

January 4, 2016 8:14 am | by Ryan Bushey, Associate Editor | Comments

A new report from research and consulting firm GlobalData forecasts exponential growth for the gastric cancer treatment market by 2024. Read more...

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Biggest Challenges Encountered When Doing SPR Experiments

December 22, 2015 8:18 am | by Mary M. Murphy, Ph.D., Applications Scientist, Reichert Technologies | Comments

Surface Plasmon Resonance (SPR) provides important information about how biomolecules interact. Information on association and dissociation kinetics and affinity can be obtained directly in real-time and label-free. Read more...

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Challenges, Trends and Opportunities for Personalized Medicine in Oncology

December 8, 2015 11:54 am | by Ralf Huss, MD, Chief Medical Officer, Definiens | Comments

Personalized medicine offers many potential benefits, from providing patients with the best care possible to reducing unnecessary costs in the healthcare system. As the industry takes steps toward personalized medicine in oncology, however, new challenges are arising just as often as new opportunities. Read more...

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Human Cell Cloning Method Dramatically Improved, says Study

November 25, 2015 10:55 am | by Cynthia Fox, Science Editor | Comments

Upping the stakes in the enduring competition between pluripotent/embryonic stem cells made via the iPSC method, and via cloning, a Harvard University group has reported dramatically improving the efficiency of cloning. Read more...

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Takeda's Tools for Fighting Infectious Diseases

November 24, 2015 9:27 am | by Ryan Bushey, Associate Editor | Comments

Rajeev Venkayya, President of the Global Vaccine Business Unit at Takeda Vaccines, chatted with Drug Discovery & Development (DDD) over the phone last month to discuss two promising vaccine candidates the company has in the pipeline. Read more...

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