Products
Fluxion Biosciences offers F1 giga-ohm seal plates for the IonFlux automated patch clamp system. The plates complement the company’s existing 20-cell ensemble recording plates and are compatible with all IonFlux systems. Users can operate both plate formats interchangeably on either the IonFlux 16 or HT systems.
IonFlux F1 plates are the industry’s first polymeric patch plates to deliver giga-ohm seal performance. This breakthrough, utilizing Fluxion’s expertise in material science, surface treatments, and microfluidics, results in a tight glass-like patch seal that approximates traditional manual patch approaches. This new plate format is intended to broaden the utility of the IonFlux System for applications where high fidelity recordings from individual cells are preferred. These include kinetic analysis, heterogeneous cell populations, endogenous expression systems such as ex-vivo primary cells, and low-expression cells.
The IonFlux system provides functional characterization of ion channels by automating the traditional patch clamp technique. This allows compound screening for the promising yet challenging ion channel drug target class in a physiologically relevant context. The IonFlux automated patch clamp system combines flexibility and simplicity with time and cost savings, and is ideal for a range of ion channel assays requiring 10 to 10,000 or more assays per day, the company reports. The IonFlux system uses a compact plate reader format, making it suitable individual research labs and high-throughput screening centers.
