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Drug Discovery & Development  
 
Health Care Moving Towards Sunday Vote
Slowly but steadily, support is building behind President Barack Obama's health care legislation in the House, the result of intense lobbying and politically targeted changes aimed at reassuring waverers and winning over critics. ...continue

FDA Panel Advises Expanding Use of Heart Implant
Federal health advisers said an electronic heart implant should be approved for a large group of heart-disease patients who currently aren't eligible for the device. ...continue

WHO Unsure if Drug-Resistant TB Getting Worse
The World Health Organization says it doesn't have enough information to know if it is winning the fight against drug-resistant tuberculosis. ...continue

AstraZeneca Wins First Seroquel Trial
British drugmaker AstraZeneca wins the first trial brought by a patient alleging its psychiatric drug Seroquel caused harm. ...continue

Teva to Acquire Ratiopharm for $5B
Israeli drug maker Teva has beaten out rivals Pfizer and Actavis to acquire German generic drug maker Ratiopharm GmbH - in a deal worth some euro3.6 billion, or nearly $5 billion. ...continue

More Headlines



Digital Camera
hamamatsuHamamatsu introduces the new ORCA-Flash2.8, our first high-sensitivity digital camera based on a next-generation scientific CMOS image sensor. ...continue

Capillary Kits
Dionex Corporation has released of five new Viper capillary kits for the UltiMate 3000 intelligent LC (LCi) solutions including Tandem Operation, Automated Application Switching, on-line SPE, Parallel LC, and Automated Method Scouting. ...continue

Direct Drive Robot
agilentThe Agilent Direct Drive Robot (DDR) from Agilent Automation Solutions has been designed for applications like drug target discovery or drug screening, where reducing cycle times means drugs traveling to market faster. ...continue

Liquid Handling Platform
zinsserDealing with membrane proteins in lipidic mesophases is not an easy task. Until now the sample preparation has been a very tedious and time-consuming task. ...continue

Capper/Decapper
Thermo Fisher Scientific Inc., the world leader in serving science, jointly introduced the new Capit-All IS Automated Capper/Decapper with The Automation Partnership. ...continue

More New Technologies

FDA Approves Rituxan for CLL
The U.S. Food and Drug Administration approved Rituxan (rituximab) to treat certain patients with chronic lymphocytic leukemia (CLL), a slowly progressing blood and bone marrow cancer. ...continue

Tasigna Recieving Priority Review
Novartis AG said its leukemia drug candidate Tasigna received priority review by the Food and Drug Administration. ...continue

Researchers Target Self-Cannibalizing Cancer Cells
A team of scientists from Princeton University and The Cancer Institute of New Jersey has embarked on a major new project to unravel the secret lives of cancer cells that go dormant and self-cannibalize to survive periods of stress. ...continue

More Advances in Cancer Research

White Papers
Developing, executing and managing the transformation, analysis and submission of clinical research data with SAS® Drug Development
“The medical product development process is no longer able to keep pace with basic scientific innovation.”  Those are harsh words, especially coming from the U.S. Food and Drug Administration (Challenge and Opportunity on the Critical Path for New Medical Products, FDA, March 2004).  Discovery organizations are identifying a lot of promising compounds, but clinical research processes haven’t kept pace with timely testing of all those potential therapies.  The FDA’s Critical Path Initiative makes it clear—it is time for innovation. ...continue

Rotavirus: Multiple Serotypes and the Argument for Rotavirus Vaccination
National pediatric infectious disease experts address the latest scientific information available on rotavirus. ...continue

Peristaltic versus Piston Pumps for Biopharmaceutical Dispensing
Peristaltic versus Piston Pumps for Biopharmaceutical Dispensing, Watson-Warlow Flexicon Peristaltic pump design innovations have been developed to dispense injectable drugs, reducing cost of bringing new drugs to market. The pumps can can the way products are mass-produced. Read more of this white paper. ...continue

More White Papers



Cell Culture Goes Hollywood
marchcoverNew tools help researchers monitor and capture the reality and drama of cell biology. ...continue

    Drug Discovery

    Drug Development

    Genomics & Proteomics

    Policy & Projections

    Technology Advances

Genomic Analysis Tools
Applied Biosystems launched the MeltDoctor High-Resolution Melt (HRM) Reagents genomic analysis tools that will help researchers in studies that associate genetic variation with specific diseases. ...continue

RIKEN Center Chooses Genedata Expressionist for Proteomics R&D
The Japanese research foundation RIKEN has chosen Genedata Expressionist to support biomarker development for cancer research. ...continue

GWAS Microarray
Illumina offers the HumanOmniExpress BeadChip (OmniExpress) microarray for genome-wide association studies (GWAS). ...continue

DNA of Fatal Attraction Star Sequenced
Illumina, Inc. has sequenced the DNA of American actress Glenn Close, the first publicly named female to have her DNA sequenced to full coverage. ...continue

Genotyping Solution Based on HRM Technology
QIAGEN offers the Type-it HRM PCR Kit and Rotor-Gene ScreenClust HRM Software, HRM (high resolution melting) technology enabling fast, accurate genotyping results. ...continue

Microdroplet PCR Enrichment for Large-Scale Population Studies
Data generated using microdroplet PCR technology as an enrichment method is particularly well suited for performing sequence-based association studies, according to researchers. ...continue

Kimmel Cancer Center Uses febit’s NGS Solutions
The Cancer Genomic Microarray Facility at the Kimmel Cancer Center selected febit’s Geniom RT Analyzer to advance its biomedical research by targeted Next-Generation Sequencing (NGS), genome-wide single nucleotide polymorphism (SNP) and microRNA (miRNA) analysis. ...continue

More Technology Spotlight

PET Imaging of Tumor Proliferation
Positron emission tomography (PET) is an imaging technology that produces three-dimensional images of positron-emitting radioisotope distribution, typically after an intravenous injection of a radioisotope-labeled tracer. ...continue

Imaging Disease with Near-Infrared Fluorescent Probes
In vivo imaging has enormous potential for drug development, and optical imaging with fluorophore-labeled probes is a popular approach. ...continue

Dynamic Dual-Gated Preclinical PET Imaging
siemensAs is common in all drug discovery and development projects, upon the identification of promising lead compounds, the next steps usually involve initial safety tests in animal subjects. ...continue

More How It Works


 

BLP25 Liposome Vaccine for Lung And Breast Cancer
blp25BLP25 Liposome Vaccine is an investigational therapeutic cancer vaccine currently being evaluated for the treatment of unresectable, stage III non-small cell lung cancer (NSCLC) and inoperable, locally advanced, recurrent, or metastatic breast cancer. ...continue

Integrin Inhibitors For Targeting Cancer
emdseronoCilengitide is the first in a new class of investigational targeted anti-cancer therapies—called integrin inhibitors—to reach Phase 3 development. ...continue

PET Imaging of Tumor Proliferation
Positron emission tomography (PET) is an imaging technology that produces three-dimensional images of positron-emitting radioisotope distribution, typically after an intravenous injection of a radioisotope-labeled tracer. ...continue

Imaging Disease with Near-Infrared Fluorescent Probes
In vivo imaging has enormous potential for drug development, and optical imaging with fluorophore-labeled probes is a popular approach. ...continue

Dynamic Dual-Gated Preclinical PET Imaging
siemensAs is common in all drug discovery and development projects, upon the identification of promising lead compounds, the next steps usually involve initial safety tests in animal subjects. ...continue

More Recommended Reading

Divestiture of MDS Pharma Services Completed
MDS Inc., announced the completion of the divestiture of the remaining MDS Pharma Services (Discovery through Phase IIa) operations to Ricerca Biosciences LLC. ...continue

Ricerca to Acquire Early-Stage Portion of MDS Pharma
Ricerca Biosciences, LLC, announced its execution of a purchase agreement to acquire the Discovery and Preclinical business of MDS Pharma Services with facilities in Bothell, Washington; Lyon, France; and Taipei, Taiwan. ...continue

PPD Opens Research Facility in Ireland
PPD, Inc. has officially opened its contract research facility in Athlone, Ireland, which includes an 18,000-square-foot analytical testing laboratory and clinical supplies business. ...continue

More CRO News

FDA Approves Treatment for NAGS Deficiency
The U.S. Food and Drug Administration has approved Carbaglu (carglumic acid) Tablets to treat a condition that results in too much ammonia in the blood. ...continue

EMA Grants Adienne Marketing Rights for Tepadina
ADIENNE Pharma & Biotech and RIEMSER Arzneimittel AG announced that the European Medicines Agency (EMA) has granted the exclusive marketing authorization to ADIENNE Pharma & Biotech for the orphan medicinal product TEPADINA for conditioning treatment prior to haematopoietic progenitor cell transplantation. ...continue

Abraxane Shows Positive Results in Phase 3 Trial
An international lung cancer trial has shown positive results in those patients treated with leading breast cancer drug ABRAXANE in combination with carboplatin. ...continue

More Drug Pipeline




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