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Protein Injection Halts Diabetes in Mice

July 17, 2014 1:36 pm | Videos | Comments

In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days. The discovery could lead to a new generation of diabetes drugs. Read more...

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DDD Update

Daily news and top headlines for drug research professionals

Gold Nanoparticles Penetrate Cells, Show Promise for Drug Delivery

July 21, 2014 3:09 pm Videos Comments

A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells. Read more...                          

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OptiNose Posts Positive Results for New Migraine Treatment

June 10, 2014 3:00 pm Videos Comments

OptiNose announced that the COMPASS trial, a head-to-head comparison of the investigational treatment AVP-825 to sumatriptan tablets, currently the most widely used prescription medication for migraine, met the primary endpoint of greater reduction in migraine pain during the first 30 minutes after treatment. Read more...

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The Promise of Personalized Medicine: An Apples-to-Apples Approach

May 16, 2014 11:04 am Videos Comments

In our sixth video, Andrew Wiecek wraps up the discussion by taking a look at one of the therapeutic areas that could be significantly improved by personalized medicine: cancer. The approach is similar to comparing apples to apples, he says. Watch more...

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Measles Vaccine Promising Against Multiple Myeloma

May 15, 2014 10:27 am Videos Comments

Researchers have demonstrated that virotherapy— destroying cancer with a virus that infects and kills cancer cells but spares normal tissues— can be effective against the deadly cancer multiple myeloma. Read more...          

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The Power of Personalized Medicine: It’s in the Stars

May 1, 2014 1:51 pm Videos Comments

In today's video, Rob Fee returns to discuss the power of genetic testing and preemptive medicine. But how do you learn if you carry risky genes, and most importantly, what do you do with that information? Read more...        

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Scientists Discover Osmotic Engine Model

May 1, 2014 12:56 pm Videos Comments

Johns Hopkins researchers have discovered a new mechanism that explains how cancer cells spread through extremely narrow three-dimensional spaces in the body by using a propulsion system based on water and charged particles. Read more...    

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A Cinderella Story: Stem Cells in Personalized Medicine

April 17, 2014 11:00 am Videos Comments

In part four of our video series, Andrew Wiecek is back to discuss the role that induced pluripotent stem (iPS) cells play in personalized medicine. How do they help? Well, iPS cells are kind of like Cinderella's glass slipper. Watch more...

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New Drug Prevents Tumor Growth by Inhibiting Key Enzyme

April 4, 2014 10:19 am Videos Comments

A ground-breaking has shown that fast-growing cancer cells are sensitive towards imbalances in the metabolism of nucleotides, the building blocks of DNA. This vulnerability can be exploited for a radically novel antitumor therapeutic approach. Read more...

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How Personalized Medicine Works: Bioinformaticians to the Rescue

April 3, 2014 10:23 am Videos Comments

In our third video, Rob Fee is back to discuss how informatics can help to overcome one of the biggest challenges in personalized medicine: organizing and examining the mountains of data that are generated during the gene sequencing process. Rob's advice? Find a bioinformatician...fast!

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How Personalized Medicine Works: Bananas and Biomarkers

March 20, 2014 11:13 am Videos Comments

In today's video, Andrew Wiecek discusses how personalized medicine works by highlighting the importance of biomarkers (and bananas) and showing that they play a key role in identifying genetic variations associated with disease.       

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The Benefits of Personalized Medicine: What Is It?

March 6, 2014 3:14 pm Videos Comments

Personalized medicine is a term you hear a lot in life science and drug industry discussions. Follow along as Rob Fee, Editor-in-Chief of Bioscience Technology, introduces the first video in a six-part series from both Drug Discovery & Development and Bioscience Technology that will explain what personalized medicine is, how it works and the potential of this concept.

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Stem Cell Discovery Leads to Trial for Heart Failure Patients

January 21, 2014 10:55 am Videos Comments

Cardio3 BioSciences, an international Mayo Clinic collaborator, has received FDA approval for a Phase 3 pivotal clinical trial of its stem cell therapy. Watch the video to see how stem cells are being used to treat people with heart failure.   

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New Therapeutic Target for Huntington's Identified

January 8, 2014 1:00 pm Videos Comments

Stephen Ferguson, a scientist at Western's Robarts Research Institute, and Fabiola Ribeiro of the Universidade Federal de Minas Gerais in Brazil found a definite improvement in motor behaviors in a HD mouse model when one of the major neurotransmitters in the brain was deleted. Which one? Find out...

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Cancer Immunotherapy Tops Science's 2013 Breakthroughs List

December 20, 2013 11:50 am Videos Comments

The cancer research community experienced a sea change in 2013 as a strategy, decades in the making, finally cemented its potential. Promising results emerged from clinical trials of cancer immunotherapy, in which treatments target the body's immune system rather than tumors directly. Read more...

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New 3-D Microscope Promises Faster Drug Therapies

December 17, 2013 1:32 pm Videos Comments

Researchers at the University of Missouri have developed a three-dimensional microscope that will yield unparalleled study of membrane proteins and how they interact on the cellular level. Could these microscopes help pharmaceutical companies bring drugs to market faster? Find out...

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