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The Lead

Antidepressants Prescribed For More Than Depression

May 25, 2016 | by Stephanie Guzowski, Editor | Comments

Physicians are prescribing antidepressants for many reasons that range beyond a depression diagnosis. So says a recent study published in the Journal of the American Medical Association.

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Restoring Chemotherapy Sensitivity by Boosting MicroRNA Levels

May 27, 2016 10:15 am | by Georgia Institute of Technology | Comments

By increasing the level of a specific microRNA (miRNA) molecule, researchers have for the first time restored chemotherapy sensitivity in vitro to a line of human pancreatic cancer cells that had developed resistance to a common treatment drug.

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Report: 1st U.S. Case of Germ Resistant to Last-Resort Drug

May 27, 2016 10:05 am | by Mike Stobbe, AP Medical Writer | Comments

For the first time, a U.S. patient has been infected with bacteria resistant to an antibiotic used as a last resort treatment, scientists said Thursday.

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Large-Scale Proteogenomic Breast Cancer Study Provides Insight into Potential Therapeutic Targets

May 27, 2016 9:55 am | by Baylor College of Medicine | Comments

Building on data from The Cancer Genome Atlas (TCGA) project, a multi-institutional team of scientists has completed the first large-scale "proteogenomic" study of breast cancer, linking DNA mutations to protein signaling and helping pinpoint the genes that drive can

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Pregnant Women with Zika Have Up to 13% Risk of Microcephaly

May 27, 2016 9:55 am | by New England Journal of Medicine | Comments

Pregnant women infected with the Zika virus during the first trimester have a risk of up to 13 percent that their infant will be born with the microcephaly birth defect, a new study says.

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Human Amyloid-Beta Acts as Natural Antibiotic in Brains of Animal Models

May 27, 2016 9:55 am | by Massachusetts General Hospital | Comments

A new study from Massachusetts General Hospital (MGH) investigators provides additional evidence that amyloid-beta protein - which is deposited in the form of beta-amyloid plaques in the brains of patients with Alzheimer's disease - is a normal part of the innate immune system.

Researchers Slowly Homing in on Risk of Zika Birth Defect

May 26, 2016 9:48 am | by Mike Stobbe, AP Medical Writer | Comments

As the international epidemic of Zika virus disease has unfolded and led to devastating birth defects for at least 1,300 children in eight countries, an agonizing question has persisted: What is the chance that an infected pregnant woman will have a baby with these defects?

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Bridging the Divide Between Doctors, Data Scientists

May 26, 2016 9:29 am | Comments

While new medical discoveries and innovations are in the news every day, doctors struggle daily with using information and techniques available right now while carefully adopting new concepts and treatments.

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Biden to Host National Cancer Research Summit in Washington

May 26, 2016 9:17 am | by Josh Lederman, Associated Press | Comments

Vice President Joe Biden will bring together scientists, oncologists, donors and patients for a national conference on cancer research in Washington, the White House said Tuesday.

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EMA Accepts Submission for Rituximab Biosimilar

May 26, 2016 9:08 am | Comments

Sandoz is committed to increasing patient access to high-quality, life-enhancing biosimilars.

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EU Lifts Suicide Warning on Pfizer's Smoking-Cessation Pill

May 26, 2016 9:08 am | by Linda A. Johnson, AP Medical Writer | Comments

Europe's main drug regulator has lifted a 7-year-old warning about possible suicidal risks from Chantix, Pfizer's smoking-cessation pill.

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TB Drug May Also Target Visceral Leishmaniasis

May 25, 2016 3:00 pm | by University of Dundee | Comments

Visceral leishmaniasis is a disease which blights the developing world with 200,000 to 400,000 new cases and 48,000 deaths annually. 

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FDA Accepts Allergan's NDA Filing for Oxymetazoline HCI Cream

May 25, 2016 8:41 am | Comments

The drug is a topical prescription for treating persistent facial erythema.

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Scientists Gain Better Look at How HIV Infects, Controls Host Cells

May 25, 2016 8:36 am | by Rockefeller University | Comments

Viruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion.

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UCB Faces U.S. Patent Challenge for Epilepsy Drug

May 25, 2016 8:29 am | by Wout Vergauwen, Reuters | Comments

This is the latest round in a legal battle between the Belgian pharmaceutical company and generic rivals.

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Harnessing Nature's Vast Array of Venoms for Drug Discovery

May 25, 2016 8:27 am | by Scripps Research Institute | Comments

There are lessons to be learned from venoms.

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