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Hydrogen Sulfide Could Help Lower Blood Pressure

January 30, 2015 | by University of Exeter | Comments

Research has indicated that a new compound, called AP39, could be beneficial in cases of high blood pressure and diseases of the blood vessels that occur with ageing and diabetes. Read more...            

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DDD Update

Daily news and top headlines for drug research professionals

Study Reveals More Dangers of Smoking While Pregnant

January 30, 2015 9:37 am | by University of Aberdeen | Comments

Smoking while pregnant causes chemical changes to the DNA of a foetus detectable from as early as 12 weeks and may predispose children born to smokers to a range of health conditions which last throughout life. Read more...      

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Dopamine Neurons Study Could Improve Mobility, Neurological Disorder Research

January 30, 2015 9:13 am | by University of Leicester | Comments

University team find for the first time when and why dopamine releasing cells in the forebrain are activated. Read more...                       

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New Biological Evidence Reveals Link Between Brain Inflammation, Depression

January 29, 2015 10:46 am | by Centre for Addiction and Mental Health | Comments

A new study by the Centre for Addiction and Mental Health (CAMH) found that the measure of brain inflammation in people who were experiencing clinical depression was increased by 30 percent. The findings, published today in JAMA Psychiatry, have important implications for developing new treatments for depression. Read more..

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Immune Cells are Ally, Not Enemy, in Battle Against Alzheimer's

January 29, 2015 10:33 am | by Yale University | Comments

Beta-amyloid is a sticky protein that aggregates and forms small plaques in the brains of the elderly and is thought to be a cause of Alzheimer's disease. Because specialized immune cells always surround these plaques, many have theorized that these cells are responsible for inflammation and damage to surrounding brain cells. Read more..

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New Approach to Delay Alzheimer's Onset to Be Tested

January 29, 2015 10:22 am | by Alzheimer's Drug Discovery Foundation | Comments

The Alzheimer's Drug Discovery Foundation (ADDF) announced a $900,000 grant to AgeneBio, a pharmaceutical company developing innovative therapies for neurologic and psychiatric diseases. Read more...                       

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3D Enzyme Model Provides New Tool for Drug Development

January 29, 2015 10:16 am | by UC San Diego | Comments

Phospholipase A2 (PLA2) enzymes are known to play a role in many inflammatory diseases, including asthma, arthritis and atherosclerosis. It then stands to reason that PLA2 inhibitors could represent a new class of anti-inflammatory medication. Read more...

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Arizona Monitoring Hundreds for Measles Linked to Disneyland

January 29, 2015 10:03 am | by Felicia Fonseca, Associated Press | Comments

A measles outbreak in Arizona that originated at California's Disney parks is at risk of increasing dramatically in size as health officials keep tabs on 1,000 people, including nearly 200 children who could have been exposed at a Phoenix-area medical center.

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AstraZeneca Announces New Genome Editing Collaborations

January 29, 2015 9:21 am | Comments

AstraZeneca announced four research collaborations aimed at harnessing the power of CRISPR, a pioneering genome-editing technique, across its entire discovery platform in the company’s key therapeutic areas. Read more...       

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Rotavirus Vaccine Reduces Severe Diarrhea by 64 Percent

January 29, 2015 9:12 am | by University of Liverpool | Comments

Researchers have found that diarrhoea caused by rotavirus infection is significantly reduced in the developing world with the use of a vaccine to prevent the condition. Read more...             

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Roche, Qualcomm to Collaborate on Remote Patient Monitoring

January 29, 2015 9:04 am | Comments

This is a strategic collaboration to improve remote monitoring and management of chronic disease patients. Read more...                        

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New Method for Identifying Aggressive Childhood Cancers

January 29, 2015 8:58 am | by Lund University | Comments

When a cancerous cell divides, the chromosomes often end up in the wrong place, or break and combine in incorrect ways. Read more....                     

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Atlas Genetics Completes $20M Series C Fundraising

January 29, 2015 8:54 am | Comments

Atlas develops ultra-rapid point-of-care diagnostic tests for infectious diseases. Read more...                            

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WHO: Ebola Response Shifts to Ending Epidemic

January 29, 2015 8:47 am | by Maria Cheng - AP Medical Writer | Comments

Health officials are now focused on ending the biggest-ever Ebola outbreak rather than just slowing the deadly virus' spread, the World Health Organization said Thursday. Read more...             

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Swiss Drug Maker Novartis Posts Q4 Profit Drop

January 28, 2015 12:04 pm | by Associated Press | Comments

Swiss pharmaceutical giant Novartis AG says fourth quarter net income dropped 26 percent but the company still posted a healthy 2014 annual profit. Read more...                                 

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Possible Therapeutic Target for Brain Blood Vessel Disorder

January 28, 2015 11:56 am | by University of Pennsylvania | Comments

Tens of millions of people around the world have abnormal, leak-prone sproutings of blood vessels in the brain called cerebral cavernous malformations (CCMs). These abnormal growths can lead to seizures, strokes, hemorrhages, and other serious conditions, yet their precise molecular cause has never been determined. Read more...

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