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FDA Approves Janssen's B-Cell Lymphoma Treatment

January 30, 2015 | Comments

This is the first therapy indicated specifically for patients with Waldenström’s macroglobulinemia. Read more...                         

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DDD Update

Daily news and top headlines for drug research professionals

White House: Science Indicates Parents Should Vaccinate Kids

January 30, 2015 4:29 pm | by Nedra Pickler - Associated Press | Comments

Amid the measles outbreak stemming from California, the White House is telling parents that science indicates they should vaccinate their children. Read more...                 

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Insurers May Be Using Drug Costs to Discriminate

January 30, 2015 4:22 pm | by Kelli Kennedy - Associated Press | Comments

One of the cornerstones of President Obama's signature health law forbids insurance companies from turning away people with pre-existing conditions such as diabetes or cancer. Read more...            

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Obama Proposes 'Precision Medicine' to End One-Size-Fits-All

January 30, 2015 10:48 am | by Lauran Neergard - AP Medical Writer | Comments

President Barack Obama is calling for an investment to move away from one-size-fits-all-medicine, toward an approach that tailors treatment to your genes. Read more...                

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AbbVie Reports Better-Than-Expected 4Q on Humira Sales

January 30, 2015 10:36 am | by Associated Press | Comments

Drugmaker Abbvie posted better-than-expected adjusted results for the fourth quarter on Friday due to double-digit growth of its blockbuster anti-inflammatory drug Humira. Read more...             

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Study Reveals More Dangers of Smoking While Pregnant

January 30, 2015 9:37 am | by University of Aberdeen | Comments

Smoking while pregnant causes chemical changes to the DNA of a foetus detectable from as early as 12 weeks and may predispose children born to smokers to a range of health conditions which last throughout life. Read more...      

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Hot on the Trail of the Hepatitis-Liver Cancer Connection

January 30, 2015 9:26 am | by Riken Institute | Comments

Scientists have for the first time demonstrated the profound effect that chronic hepatitis infection and inflammation can have on the genetic mutations found in tumors of the liver. Read more...           

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Hydrogen Sulfide Could Help Lower Blood Pressure

January 30, 2015 9:19 am | by University of Exeter | Comments

Research has indicated that a new compound, called AP39, could be beneficial in cases of high blood pressure and diseases of the blood vessels that occur with ageing and diabetes. Read more...            

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Dopamine Neurons Study Could Improve Mobility, Neurological Disorder Research

January 30, 2015 9:13 am | by University of Leicester | Comments

University team find for the first time when and why dopamine releasing cells in the forebrain are activated. Read more...                       

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Valeant Pharmaceuticals Selected as Lead Bidder to Acquire Dendreon

January 30, 2015 9:03 am | Comments

Valeant Pharmaceuticals announced that it has entered into a "stalking horse" asset purchase agreement to acquire certain assets of Dendreon Corporation and the company's immunotherapy treatment. Read more...         

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New Biological Evidence Reveals Link Between Brain Inflammation, Depression

January 29, 2015 10:46 am | by Centre for Addiction and Mental Health | Comments

A new study by the Centre for Addiction and Mental Health (CAMH) found that the measure of brain inflammation in people who were experiencing clinical depression was increased by 30 percent. The findings, published today in JAMA Psychiatry, have important implications for developing new treatments for depression. Read more..

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Immune Cells are Ally, Not Enemy, in Battle Against Alzheimer's

January 29, 2015 10:33 am | by Yale University | Comments

Beta-amyloid is a sticky protein that aggregates and forms small plaques in the brains of the elderly and is thought to be a cause of Alzheimer's disease. Because specialized immune cells always surround these plaques, many have theorized that these cells are responsible for inflammation and damage to surrounding brain cells. Read more..

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New Approach to Delay Alzheimer's Onset to Be Tested

January 29, 2015 10:22 am | by Alzheimer's Drug Discovery Foundation | Comments

The Alzheimer's Drug Discovery Foundation (ADDF) announced a $900,000 grant to AgeneBio, a pharmaceutical company developing innovative therapies for neurologic and psychiatric diseases. Read more...                       

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3D Enzyme Model Provides New Tool for Drug Development

January 29, 2015 10:16 am | by UC San Diego | Comments

Phospholipase A2 (PLA2) enzymes are known to play a role in many inflammatory diseases, including asthma, arthritis and atherosclerosis. It then stands to reason that PLA2 inhibitors could represent a new class of anti-inflammatory medication. Read more...

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Arizona Monitoring Hundreds for Measles Linked to Disneyland

January 29, 2015 10:03 am | by Felicia Fonseca, Associated Press | Comments

A measles outbreak in Arizona that originated at California's Disney parks is at risk of increasing dramatically in size as health officials keep tabs on 1,000 people, including nearly 200 children who could have been exposed at a Phoenix-area medical center.

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AstraZeneca Announces New Genome Editing Collaborations

January 29, 2015 9:21 am | Comments

AstraZeneca announced four research collaborations aimed at harnessing the power of CRISPR, a pioneering genome-editing technique, across its entire discovery platform in the company’s key therapeutic areas. Read more...       

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