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Bioethicists Say Ebola Drugs Must be Fairly Distributed, Tested Ethically

August 22, 2014 | Comments

Researchers and health authorities need to ensure that experimental drugs to treat Ebola are distributed fairly, and in the context of randomized controlled trials in collaboration with local communities and other stakeholders, according to a new Viewpoint, published in The Lancet. Read more...

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DDD Update

Daily news and top headlines for drug research professionals

Pomegranate-Based Drug to Stem Alzheimer’s, Parkinson’s

August 22, 2014 3:31 pm | Comments

The onset of Alzheimer’s disease can be slowed and some of its symptoms curbed by a natural compound that is found in pomegranate, according to new findings. Read more...                        

Combining Vaccines Boosts Polio Immunity

August 22, 2014 3:11 pm | by Lauran Neergaard, AP Medical Writer | Comments

New research suggests a one-two punch could help battle polio in some of the world's most remote and strife-torn regions: Giving a single vaccine shot to children who've already swallowed drops of an oral polio vaccine greatly boosted their immunity. Read more...

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EMA Accepts Ceftolozane/Tazobactam MAA for Review

August 22, 2014 10:54 am | Comments

Cubist Pharmaceuticals announced that the European Medicines Agency has accepted for review the company’s Marketing Authorization Application for its investigational antibiotic ceftolozane/tazobactam for the treatment of complicated urinary tract Infections and complicated intra-abdominal infections. Read more...

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Mutated Polio Virus Breaches Vaccine Protection

August 22, 2014 10:48 am | Comments

Scientists of the University of Bonn, together with colleagues from Gabon, are reporting alarming findings: a mutated polio virus that was able to resist the vaccine protection to a considerable extent was found in victims of an outbreak in the Congo in 2010. Read more...

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AstraZeneca, Illumina Partner on Gene Sequencing

August 21, 2014 4:12 pm | Comments

AstraZeneca announced that it has entered into a collaboration with gene sequencing company, Illumina Inc., to develop its next generation sequencing platform for companion diagnostic tests applicable across AstraZeneca’s oncology portfolio. Read more…

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FDA Clears Eliquis for New Use Against Blood Clots

August 21, 2014 3:28 pm | by The Associated Press | Comments

Bristol-Myers Squibb and Pfizer said Thursday that federal regulators have expanded approval of their blood thinner Eliquis to treat two types of dangerous blood clots. Read more...                    

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New Hydrocodone Restrictions to Take Effect

August 21, 2014 1:00 pm | Comments

The federal government is finalizing new restrictions on hundreds of medicines containing hydrocodone, the highly addictive painkiller that has grown into the most widely prescribed drug in the U.S. Read more...            

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Botox Injections Slow Growth of Stomach Tumors

August 21, 2014 1:00 pm | Comments

New research shows that nerves may play a critical role in stomach cancer growth and that blocking nerve signals using Botox (onabotulinumtoxinA) could be an effective treatment for the disease. Read more...             

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Both American Ebola Patients Discharged from Hospital

August 21, 2014 1:00 pm | by Jeff Martin and Katie Foody | Comments

After nearly three weeks of treatment, the two American aid workers who were infected with the deadly Ebola virus in Africa have been discharged from an Atlanta hospital, officials said Thursday. Read more...            

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Eisai Submits EU Marketing Authorization for Anti-Epileptic

August 21, 2014 11:34 am | Comments

Eisai has submitted a Marketing Authorization Application to the European Commission for its first-in-class anti-epileptic drug (AED) Fycompa (perampanel) as an adjunctive treatment of primary generalized tonic-clonic seizures (PGTC). Read more...

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FDA Approves GSK Asthma Drug

August 21, 2014 11:29 am | Comments

GlaxoSmithKline plc announced that the FDA has approved Arnuity Ellipta (fluticasone furoate inhalation powder), a once-daily inhaled corticosteroid (ICS) medicine for maintenance treatment of asthma as prophylactic therapy in patients aged 12 years and older. Read more...

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Psoriasis Drug Fares Well in Late-Stage Trial

August 21, 2014 11:25 am | Comments

Drugmaker Eli Lilly and Co. said its potential psoriasis treatment fared better than both a fake drug and a competitor's product during late-stage testing on patients with the most common form of the skin disease and plans to submit the product, ixekizumab, to regulators in the first half of next year. Read more...

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Researchers Restore Protein in Muscular Dystrophy

August 21, 2014 11:19 am | Comments

For the first time, a research team has succeeded in restoring a missing repair protein in skeletal muscle of three patients with muscular dystrophy carrying a dysferlin mutation who received a single systemic dose of a proteasome inhibitor. Read more...

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Ebola: Slum Calm; Aid Worker Recovers

August 21, 2014 11:12 am | by Jonathan Paye-Layleh, Associated Press | Comments

Calm returned Thursday to a slum in the Liberian capital that was sealed off in the government's attempt to halt the spread of Ebola, a day after clashes erupted between residents and security forces, and in the United States, an aid worker who was infected in Liberia has recovered. Read more...

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Novan’s Topical Treatment Shows Efficacy Against Drug-resistant Bugs

August 20, 2014 2:29 pm | Comments

Novan Therapeutics announced that the company’s Nitricil platform technology has been shown to be efficacious against several of the most multi-drug resistant pathogens plaguing civilian and military health care providers across the globe. Read more...

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