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Novartis, Aduro: Up-to-$750M Cancer Immunotherapy Collaboration

March 30, 2015 | by Stephanie Guzowski, Editor | Comments

Novartis is planning to boost its cancer immunotherapy pipeline with a collaboration with California-based Aduro Biotech worth up to $750 million. Read more...

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DDD Update

Daily news and top headlines for drug research professionals

GeoVax HIV Vaccine Moves Forward

April 1, 2015 1:40 pm | Comments

GeoVax Labs, a biotechnology company developing human vaccines for Ebola and HIV, today announced that the HIV Vaccine Trials Network (HVTN) has assigned a trial number, HVTN 114, to the next clinical trial of its clade B preventive HIV vaccine candidate. Read more...


Pharmacist Group Says Members Shouldn't Aid in Executions

April 1, 2015 1:34 pm | by Julie Watson, The Associated Press | Comments

In a move that could heighten the hurdles faced by states attempting to execute prisoners, a leading association for U.S. pharmacists has officially discouraged its members from providing drugs for use in lethal injections. Read more...


Drilling Down to Genetic Root of Prostate Tumor Development

April 1, 2015 1:26 pm | by Cancer Research UK | Comments

Scientists have revealed the root of prostate cancers in individual men, discovering that despite huge genetic variety between tumours they also share common gene faults - insight that could offer new treatment hopes, according to research published in Nature today. Read more..


Old Cancer Drug Could Have New Use in Fighting Cancer

April 1, 2015 1:15 pm | by University of Missouri | Comments

A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients with leukemia. Read more...


Experimental Cancer Drug Restores Memory in Mouse Model of Alzheimer’s

April 1, 2015 12:37 pm | by Yale University | Comments

Memory and as well as connections between brain cells were restored in mice with a model of Alzheimer’s given an experimental cancer drug, Yale School of Medicine researchers reported in the journal Annals of Neurology. Read more...


Actavis Selling Australian Generic Drug Unit to Amneal

April 1, 2015 10:30 am | by Associated Press | Comments

Actavis PLC is selling its generic drug business in Australia to privately-held Amneal Pharmaceuticals for an undisclosed amount. Read more...


Paracetamol is Ineffective for Lower Back Pain

April 1, 2015 10:19 am | Comments

Paracetamol is not effective in the treatment of spinal pain and provides negligible benefits for osteoarthritis, according to a study published in The BMJ. Read more...


Merck's HPV Vaccine Now Available in Canada

April 1, 2015 10:12 am | Comments

Merck, known as MSD outside the United States and Canada, announced that Gardasil 9 (Human Papillomavirus 9-valent Vaccine, Recombinant), Merck's 9-valent human papillomavirus (HPV) vaccine, is now available in Canada.  


Blood-Based Biomarkers Could Enable Accurate TB Tests for Diagnosis

March 31, 2015 11:48 am | by Emory University | Comments

Researchers have identified blood-based biomarkers in patients with active tuberculosis (ATB) that could lead to new blood-based diagnostics and tools for monitoring treatment response and cure. Read more...


Quintiles, Quest to Join to Provide Global Clinical Trials Lab Services

March 31, 2015 11:38 am | Comments

Quintiles and Quest Diagnostics announced a definitive agreement to form a global clinical trials laboratory services business. Read more...


Publication Bias, 'Spin,' Raise Questions About Anxiety Drugs

March 31, 2015 11:32 am | by Oregon State University | Comments

A new analysis reported in JAMA Psychiatry raises serious questions about the increasingly common use of second-generation antidepressant drugs to treat anxiety disorders. Read more...


Arizona Governor Signs Abortion Drug Notification Mandate

March 31, 2015 11:22 am | by Bob Christie and Ryan Van Velzer, Associate Press | Comments

Gov. Doug Ducey signed a bill Monday that requires abortion providers in Arizona to tell women they can reverse the effects of a drug-induced abortion and also bars women from buying any health care plan through the federal marketplace that includes abortion coverage. Read more...


Merck Serono, Intrexon Agree to Develop, Commercialize CAR-T Therapy

March 31, 2015 10:21 am | Comments

Merck Serono, the biopharmaceutical business of Merck, and Intrexon Corporation announced an exclusive strategic collaboration and license agreement to develop and commercialize Chimeric Antigen Receptor T-cell (CAR-T) cancer therapies. Read more...


Britain to Offer All Infants Meningitis B Vaccine

March 31, 2015 10:17 am | by Associated Press | Comments

Britain says it will become the first country to offer all babies a vaccine for potentially fatal meningitis B after it reached a price deal with GlaxoSmithKline PLC. Read more..


Development, Commercialization of Antibacterial Drugs to Speed Up

March 31, 2015 10:12 am | Comments

The growing threat posed by multi-drug resistant gram-negative organisms (MDR-GNBs) is lending a sense of urgency to the development of antibacterial drugs worldwide. Upcoming regulatory reforms to lower R&D costs and provide incentives for new drug identification will create attractive opportunities for pharmaceutical manufacturers. Read more...



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