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Novartis, Aduro: Up-to-$750M Cancer Immunotherapy Collaboration

March 30, 2015 | by Stephanie Guzowski, Editor | Comments

Novartis is planning to boost its cancer immunotherapy pipeline with a collaboration with California-based Aduro Biotech worth up to $750 million. Read more...

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DDD Update

Daily news and top headlines for drug research professionals

GeoVax HIV Vaccine Moves Forward

April 1, 2015 1:40 pm | Comments

GeoVax Labs, a biotechnology company developing human vaccines for Ebola and HIV, today announced that the HIV Vaccine Trials Network (HVTN) has assigned a trial number, HVTN 114, to the next clinical trial of its clade B preventive HIV vaccine candidate. Read more...

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Pharmacist Group Says Members Shouldn't Aid in Executions

April 1, 2015 1:34 pm | by Julie Watson, The Associated Press | Comments

In a move that could heighten the hurdles faced by states attempting to execute prisoners, a leading association for U.S. pharmacists has officially discouraged its members from providing drugs for use in lethal injections. Read more...

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Drilling Down to Genetic Root of Prostate Tumor Development

April 1, 2015 1:26 pm | by Cancer Research UK | Comments

Scientists have revealed the root of prostate cancers in individual men, discovering that despite huge genetic variety between tumours they also share common gene faults - insight that could offer new treatment hopes, according to research published in Nature today. Read more..

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Old Cancer Drug Could Have New Use in Fighting Cancer

April 1, 2015 1:15 pm | by University of Missouri | Comments

A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients with leukemia. Read more...

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Experimental Cancer Drug Restores Memory in Mouse Model of Alzheimer’s

April 1, 2015 12:37 pm | by Yale University | Comments

Memory and as well as connections between brain cells were restored in mice with a model of Alzheimer’s given an experimental cancer drug, Yale School of Medicine researchers reported in the journal Annals of Neurology. Read more...

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Actavis Selling Australian Generic Drug Unit to Amneal

April 1, 2015 10:30 am | by Associated Press | Comments

Actavis PLC is selling its generic drug business in Australia to privately-held Amneal Pharmaceuticals for an undisclosed amount. Read more...

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Paracetamol is Ineffective for Lower Back Pain

April 1, 2015 10:19 am | Comments

Paracetamol is not effective in the treatment of spinal pain and provides negligible benefits for osteoarthritis, according to a study published in The BMJ. Read more...

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Merck's HPV Vaccine Now Available in Canada

April 1, 2015 10:12 am | Comments

Merck, known as MSD outside the United States and Canada, announced that Gardasil 9 (Human Papillomavirus 9-valent Vaccine, Recombinant), Merck's 9-valent human papillomavirus (HPV) vaccine, is now available in Canada.  

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Blood-Based Biomarkers Could Enable Accurate TB Tests for Diagnosis

March 31, 2015 11:48 am | by Emory University | Comments

Researchers have identified blood-based biomarkers in patients with active tuberculosis (ATB) that could lead to new blood-based diagnostics and tools for monitoring treatment response and cure. Read more...

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Quintiles, Quest to Join to Provide Global Clinical Trials Lab Services

March 31, 2015 11:38 am | Comments

Quintiles and Quest Diagnostics announced a definitive agreement to form a global clinical trials laboratory services business. Read more...

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Publication Bias, 'Spin,' Raise Questions About Anxiety Drugs

March 31, 2015 11:32 am | by Oregon State University | Comments

A new analysis reported in JAMA Psychiatry raises serious questions about the increasingly common use of second-generation antidepressant drugs to treat anxiety disorders. Read more...

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Arizona Governor Signs Abortion Drug Notification Mandate

March 31, 2015 11:22 am | by Bob Christie and Ryan Van Velzer, Associate Press | Comments

Gov. Doug Ducey signed a bill Monday that requires abortion providers in Arizona to tell women they can reverse the effects of a drug-induced abortion and also bars women from buying any health care plan through the federal marketplace that includes abortion coverage. Read more...

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Merck Serono, Intrexon Agree to Develop, Commercialize CAR-T Therapy

March 31, 2015 10:21 am | Comments

Merck Serono, the biopharmaceutical business of Merck, and Intrexon Corporation announced an exclusive strategic collaboration and license agreement to develop and commercialize Chimeric Antigen Receptor T-cell (CAR-T) cancer therapies. Read more...

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Britain to Offer All Infants Meningitis B Vaccine

March 31, 2015 10:17 am | by Associated Press | Comments

Britain says it will become the first country to offer all babies a vaccine for potentially fatal meningitis B after it reached a price deal with GlaxoSmithKline PLC. Read more..

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Development, Commercialization of Antibacterial Drugs to Speed Up

March 31, 2015 10:12 am | Comments

The growing threat posed by multi-drug resistant gram-negative organisms (MDR-GNBs) is lending a sense of urgency to the development of antibacterial drugs worldwide. Upcoming regulatory reforms to lower R&D costs and provide incentives for new drug identification will create attractive opportunities for pharmaceutical manufacturers. Read more...

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