Drug Discovery & Development

Product Releases

Retinoid Receptor Assay
Tue, 11/13/2012 - 11:55am

Indigo Biosciences Inc., a provider of cell-based nuclear receptor reporter assay products and services, has added all nine retinoid receptor assays to the company’s suite of kits and screening services.

Indigo Biosciences provides more than two dozen individual nuclear receptor reporter assays for scientists engaged in the discovery and development of novel therapeutic agents.

The company’s retinoid receptors include retinoic acid receptors (RARs), retinoid X receptors (RXRs) and RAR-related orphan receptors (RORs). In addition, Indigo Biosciences offers all three subtypes of each retinoid receptor.

Retinoid receptors bind uniquely to retinoid compounds and directly regulate gene expression. They mediate a wide range of metabolic pathways and play important roles in vision, cell proliferation, and differentiation, growth of bone tissue, immune function, activation of tumor suppressor genes and many others. Because of their profound effects on functions throughout the body, retinoid receptors are significant drug targets.

Indigo Biosciences’ ready-to-use assay systems are simple, reliable, and accurate. The company’s lab-in-a-box assay kits can be shipped overnight so that scientists can produce data within 24 hours featuring excellent Z’ scores and high signal-to-noise ratios.

Each kit includes reporter cells, assay plates and all reagents. The products feature engineered reporter cells prepared using Indigo's CryoMite process, a long-term cryo-preservation of cells for shipping and storage and on-demand use.

In addition, Indigo Biosciences offers contract screening services for more than two dozen individual nuclear receptor reporter assays, including all nine retinoid receptors. The company provides fast turnaround times and easy-to-analyze data reports. Review Indigo Biosciences' complete catalog of on-demand screening assays.

Indigo Biosciences Inc.

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