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APR
16
Drug Discovery & Development Update
IN THIS ISSUE
  NEWS  
  Small Molecule Shows Potential in Advanced Cancers  
  NEWS  
  HPV Vaccine Works in HIV+ Women  
  NEWS  
  Baxter's Orphan Drug Candidate Hits Key Phase 3 Endpoint  
  NEWS  
  Phase 1 Results Positive for Tumor Vaccine  
  NEWS  
  Recall Hurts Abbott, But Q1 Expectations Topped  
  NEWS  
  2014 R&D 100 Awards Entry Deadline Extended  

Primary Cells: Biologically relevant for biomarkers

Clonetics™ Primary Cells are essential in research as they are derived directly from human tissue representing biological relevance. Unlike cell lines, primary cells have low mutation rate and require minimal pre-characterization.


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FEATURED STORY

Measles Drug Lowers Viral Load

Featured Story

A novel antiviral drug may protect people infected with the measles from getting sick and prevent them from spreading the virus to others, an international team of researchers said. Read more...                  


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Guide to Improving Your ChIP Assay Results

Porvair Sciences' has produced an informative new guide entitled ‘Top 10 tips for positive ChIP results’. The success of a Chromatin immunoprecipitation (ChIP) assay is highly dependent on the quality of chromatin prepared. Written by scientists with many years experience of ChIP, the new 8-page document provides an informative 10-point illustrated guide to help you improve your ChIP assay results.


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NEWS

Small Molecule Shows Potential in Advanced Cancers

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Cleveland BioLabs Inc. announced the achievement of all objectives in a Phase 1 clinical trial of CBL0102, or quinacrine, an orally administered small molecule in patients with advanced cancers for which no standard care exists or which had become resistant to conventional therapies. Read more...


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NEWS

HPV Vaccine Works in HIV+ Women

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HIV-positive women respond well to a vaccine against the human papillomavirus (HPV), even when their immune system is struggling, according to newly published results of an international clinical trial, countering doubts about whether the vaccine would be helpful. Read more...


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Mass Spec for Label-free Screening and Mechanistic Studies

Mass spectrometry is useful tool for investigating traditional biochemical inhibitor assays in a label-free manner; but standard HPLC-MS workflows are too slow to be practical in a drug discovery laboratory. This webinar will examine RapidFire-MS/MS as a high-throughput label-free screening platform for biochemical assays.


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NEWS

Baxter's Orphan Drug Candidate Hits Key Phase 3 Endpoint

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Baxter International Inc. announced topline results from a Phase 3 clinical trial evaluating the safety, efficacy and pharmacokinetics of BAX 111, a recombinant von Willebrand factor under investigation for the treatment of bleeding episodes in patients with von Willebrand disease. Read more...


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NEWS

Phase 1 Results Positive for Tumor Vaccine

Celldex Therapeutics Inc. announced that final data from its Phase 1 study of CDX-1401 (an off-the-shelf vaccine that targets dendritic cells) in solid tumors, including long-term patient follow-up, have been published in Science Translational Medicine. Read more...


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2014 Readers' Choice Awards

Laboratory Equipment magazine is proud to announce its 6th Annual Readers' Choice Awards, celebrating excellence in product design and performance for the tools and materials used by scientists and engineers in research laboratories. The deadline for receipt of entries is Friday, April 25, 2014.


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NEWS

Recall Hurts Abbott, But Q1 Expectations Topped

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Abbott Laboratories' first-quarter net income tumbled 31% on unfavorable currency exchanges and a supplier recall that lowered sales of its baby formula, but the company beat most expectations and shares edged higher in early trading Wednesday. Read more...


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NEWS

2014 R&D 100 Awards Entry Deadline Extended

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The editors of R&D Magazine have announced that there is still plenty time to prepare your Entry Form for the 2014 R&D 100 Awards: Friday, May 2 is the new deadline.                      


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NEWS

SSRI Use During Pregnancy Linked to Autism, Developmental Delays

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In a study of nearly 1,000 mother-child pairs, researchers found that prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) was associated with autism spectrum disorder (ASD) and developmental delays (DD) in boys. Read more...   


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