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Genomics/Proteomics
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The Lead

Generic Meds Boost Adherence to Breast Cancer Therapy

October 29, 2014 12:30 pm | News | Comments

 A study by Columbia University Medical Center researchers has found that the introduction of generic aromatase inhibitors increased cancer treatment adherence. Read more...             

Genetic Link to Kidney Stones Identified

October 29, 2014 10:14 am | News | Comments

A new breakthrough could help kidney stone sufferers get an exact diagnosis and specific...

Protein Discovery May Unlock New HIV Treatment

October 24, 2014 1:48 pm | News | Comments

Scientists at the Salk Institute have uncovered a new protein that participates in active HIV...

Researchers Find New Target for Treating Childhood Cancers

October 24, 2014 10:31 am | News | Comments

Scientists at the University of Liverpool have uncovered a new target for drugs that could...

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Myriad Establishes New Tumor Research Lab in Europe

October 24, 2014 10:18 am | News | Comments

Myriad Genetics Inc. announced it has established a Tumor BRACAnalysis CDx laboratory in Europe. Read more...                                                        

New Genome Analysis Finds Markers of Aggresive Tumors

October 23, 2014 1:21 pm | News | Comments

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients. Read more...    

Advances in Protein Detection and Quantitation Methods

October 7, 2014 8:30 am | by Nuno Goncalves, Manager of Novel Biomolecular Detection, EMD Millipore | Articles | Comments

Protein detection and quantitation is required daily in thousands of laboratories worldwide for activities ranging from protein characterization to clinical diagnostic testing to drug dosing. Read more...                

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Researchers Engineer New Mouse Model to Study Disease

September 26, 2014 3:33 pm | News | Comments

Researchers from the Broad Institute and MIT have created a new mouse model to simplify application of the CRISPR-Cas9 system for genome-editing experiments in living animals. Read more...

New Approach Aims to Silence Cancer 'Survival Genes'

September 23, 2014 11:20 am | News | Comments

Scientists are working on a promising new approach for tackling colorectal cancer, the second most common cause of cancer-related death. Read more...                             

'Evolved' Protein Created to Stop Cancer from Spreading

September 22, 2014 9:25 am | News | Comments

A team of researchers has developed a protein therapy that disrupts the process that causes cancer cells to break away from original tumor sites, travel through the bloodstream and start aggressive new growths elsewhere in the body. Read more... 

Researchers ID New Genetic Target for a Different Kind of Cancer Drug

September 9, 2014 11:13 am | News | Comments

Researchers have discovered that the protein RBM4, a molecule crucial to the process of gene splicing, is drastically decreased in multiple forms of human cancer, including lung and breast cancers. Read more...            

Single Animal-to-Human Transmission Event Sparked 2014 Ebola Outbreak

September 2, 2014 10:32 am | News | Comments

Scientists used advanced genomic sequencing technology to identify a single point of infection from an animal reservoir to a human in the current Ebola outbreak in West Africa. Read more...                  

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The Future of Genome Analysis

August 28, 2014 9:30 am | by Maxim Mikheev, M.D., Ph.D., Co-Founder and Chief Technical Officer at BioDatomics | Articles | Comments

As technological improvements have changed the way we study the genome, the amount of data associated with a single DNA sample has increased exponentially. Surprisingly, throughout this evolution the hardware and software infrastructure supporting bioanalytics has barely changed. Read more...

Protein Family Can Inhibit HIV Release

August 26, 2014 10:30 am | News | Comments

A family of proteins that promotes virus entry into cells also has the ability to block the release of HIV and other viruses, researchers have found. Read more...                         

AstraZeneca, Illumina Partner on Gene Sequencing

August 21, 2014 4:12 pm | News | Comments

AstraZeneca announced that it has entered into a collaboration with gene sequencing company, Illumina Inc., to develop its next generation sequencing platform for companion diagnostic tests applicable across AstraZeneca’s oncology portfolio. Read more…

Roche, Garvan Partner on Genomics Technologies

August 20, 2014 10:18 am | News | Comments

Roche and the Garvan Institute of Medical Research announced a collaboration to develop new technologies for targeted epigenomic analysis using DNA sequencing, bringing together the genomics expertise and infrastructure at the Garvan Institute and target enrichment products from Roche NimbleGen. Read more...

Unlocking the Power of Big Data in R&D, Part Two

August 19, 2014 11:23 am | by Sharon Benzeno, PhD, MBA, Senior Director, Business Development Bioinformatics, Elsevier | Articles | Comments

Big data is one of the hottest topics in R&D as its potential to accelerate successful drug development becomes more widely recognized. Part 2 of this two-part article analyses the new data-driven decision-making approaches make a difference to life science R&D. Read more...

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Unlocking the Power of Big Data in R&D, Part One

August 15, 2014 9:09 am | by Sharon Benzeno, PhD, MBA, Senior Director, Business Development Bioinformatics, Elsevier | Articles | Comments

Big data promises big insights for drug discovery and development, but its intrinsic value will be unlocked only if R&D organizations have the tools to make sense of it. Part 1 of this two-part article looks at how new models are changing the world of R&D. Read more...

Study Reveals How Ebola Blocks Immune System

August 14, 2014 10:28 am | News | Comments

The Ebola virus, in the midst of its biggest outbreak on record, is a master at evading the body’s immune system, but researchers at Washington University School of Medicine in St. Louis and elsewhere have learned one way the virus dodges the body’s antiviral defenses, providing important insight that could lead to new therapies. Read more...

Epigenetic Cancer Cell Markers Could Improve Treatment

August 12, 2014 3:05 pm | News | Comments

Scientists have known for decades that cancer can be caused by genetic mutations, but more recently they have discovered that chemical modifications of a gene can also contribute to cancer. These alterations, known as epigenetic modifications, control whether a gene is turned on or off. Now, a team engineers has developed a fast, reliable method to detect this type of modification. Read more...

23andMe, Pfizer Collaborate on Genetics of IBD

August 12, 2014 11:24 am | News | Comments

23andMe announced an agreement with Pfizer Inc. in which the companies will aim to enroll 10,000 people with Inflammatory Bowel Disease (IBD) in a research initiative designed to explore the genetic factors associated with the onset, progression, severity and response to treatments for IBD. Read more...

Cure to Lung Cancer May Depend on Your DNA

August 7, 2014 1:00 pm | News | Comments

The Northside Hospital Cancer Institute announced its participation in a unique National Cancer Institute clinical collaboration to treat lung cancer based on a person’s genetic makeup. Read more...               

Ventana Paves the Way for Companion Diagnostics in China

August 6, 2014 10:39 am | News | Comments

Ventana Medical Systems Inc., a member of the Roche Group, announced a new agreement with Quintiles Inc. to offer College of American Pathology-standard companion diagnostic testing services in China for pharmaceutical and biotech companies conducting early phase clinical trials. Read more...

Paradigm Kicks Off Genomic Profiling for Cancer Registry

August 5, 2014 2:16 pm | News | Comments

Paradigm has announced they have initiated genomic testing for Pharmatech's AccessPPM Cancer Registry, which is designed to collect EMR data and genomic information to help best match cancer patients with targeted clinical trials. Read more... 

Scientists Use Subcellular Imaging to Visualize Glutamate Receptors

August 5, 2014 2:08 pm | News | Comments

Scientists at the National Institutes of Health have created high-resolution images of the glutamate receptor, a protein that plays a key role in nerve signaling. The advance, published online in the journal Nature, opens a new window to study protein interactions in cell membranes in exquisite detail. Read more...

BGI Buys Genome Mapping System

July 31, 2014 2:21 pm | News | Comments

BioNano Genomics announced the purchase of an Irys System by BGI, the world's largest genomics organization. BGI selected BioNano's platform to enable comprehensive exploration of human structural variation and to provide vastly improved assemblies for various organisms of interest, including those where no reference exists. Read more...

Replikin Count Predicts Ebola Outbreaks

July 31, 2014 2:14 pm | News | Comments

Replikins Ltd. released new data on changes in the gene structure of the Ebola virus showing that before the current outbreaks, the mean Ebola Reston gene Replikin Count between 1995 and 2002 was 1.1; the mean Replikin Count increased two-fold in 2010, three-fold in 2012, and sixteen-fold in 2013. Read more...

Protein Fuels Repair of Treatment-Resistant Cancer Cells

July 31, 2014 1:31 pm | News | Comments

In some highly treatment-resistant cancers, such as head and neck cancer, some cancer cells repair themselves, survive and thrive during radiation and chemotherapy. Now, University of Michigan researchers have found that a particular protein— TRIP13— encourages those cancer cells to repair themselves. Read more...

New NIH Program Will Find Potential Drug Targets

July 31, 2014 1:23 pm | News | Comments

National Institutes of Health leaders have announced a new collaborative initiative to improve human health by exploring poorly understood genes that have the potential to be modified by medicines. Read more...            

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