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Genomics/Proteomics
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The Lead

Aspirin Reduces Colon Cancer Risk for Those with Specific Gene

April 24, 2014 10:02 am | News | Comments

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene. Read more...  

'Chaperone' Compounds Offer New Approach to Alzheimer’s Treatment

April 21, 2014 10:53 am | News | Comments

A team of researchers has devised a wholly new approach to the treatment of Alzheimer’s disease...

New Gene Technology Has Therapeutic Implications

April 17, 2014 12:16 pm | News | Comments

For thousands of years humans have been tinkering with plant genetics, even when they didn’t...

Protein Partnership Inflames Immune Cells in Cancer

April 15, 2014 12:53 pm | News | Comments

Scientists have identified two unlikely partners in a type of immune cell called a macrophage...

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Expression of Tumor Suppressor Linked to Breast Cancer Survival

April 11, 2014 1:18 pm | News | Comments

A tumor-suppressing protein acts as a dimmer switch to dial down gene expression. It does this by reading a chemical message attached to another protein that's tightly intertwined with DNA, a team led by scientists at The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2014. Read more...

Study Findings May Drive Parkinson’s Treatment Research

April 11, 2014 12:51 pm | News | Comments

Scientists at Johns Hopkins University and the Institute for Cell Engineering may have discovered how the most common genetic cause of Parkinson’s disease destroys brain cells and devastates many patients worldwide. Read more...  

Yeast Provides Genetic Clues to Drug Response

April 11, 2014 10:45 am | News | Comments

Why do people respond differently to the same drug? For the first time, researchers have untangled genetic and environmental factors related to drug reactions, bringing us a step closer to predicting how a drug will affect us. Read more...   

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Plant Nanotubes May Improve Chemotherapy Treatment

April 4, 2014 1:52 pm | News | Comments

Researchers took what some would consider garbage and made a remarkable scientific tool, one that could someday help to correct genetic disorders or treat cancer without chemotherapy’s nasty side effects. Read more...         

How Personalized Medicine Works: Bioinformaticians to the Rescue

April 3, 2014 10:23 am | Videos | Comments

In our third video, Rob Fee is back to discuss how informatics can help to overcome one of the biggest challenges in personalized medicine: organizing and examining the mountains of data that are generated during the gene sequencing process. Rob's advice? Find a bioinformatician...fast!

Celgene, Forma Announce Multi-Year Strategic Alliance

April 1, 2014 2:13 pm | News | Comments

Forma Therapeutics, an R&D organization in pursuit of medicines in oncology and other therapeutic areas, announced a second strategic collaboration and option agreement with Celgene Corp. Read more...        

Experimental Cancer Drug Reverses Schizophrenia in Mice

April 1, 2014 1:17 pm | News | Comments

Johns Hopkins researchers say that an experimental anticancer compound appears to have reversed behaviors associated with schizophrenia and restored some lost brain cell function in adolescent mice with a rodent version of the devastating mental illness. Read more...

New Initiative Aims to Improve Outcomes in Metastatic Colorectal Cancer

April 1, 2014 8:53 am | News | Comments

Merck Serono, the biopharmaceutical division of Merck, announced the formation of the global Oncology Partnership and Education Network (OPEN). Read more...                

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Discovery May Help Predict Lung Cancer Treatment Success

March 25, 2014 10:01 am | News | Comments

Scientists have discovered the structure of an abnormal protein which causes an aggressive type of lung cancer, according to new research. Read more...                             

Dog DNA Plays Role in Developing New Human Therapies

March 18, 2014 2:35 pm | News | Comments

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a new proof-of-concept study. Read more...                           

Study Proposes New Ovarian Cancer Targets

March 13, 2014 3:31 pm | News | Comments

Proteins called TAFs were once thought to be generic cogs in the machinery of gene expression, but in a new study scientists propose that they may be important suspects in the progression of ovarian cancer that should not continue to be overlooked. Read more...

Program Simulates Activation of Cancer Protein, May Lead to New Drug Design

March 7, 2014 1:12 pm | News | Comments

Folding@home, a program that taps the idle processing time of 200,000 personal computers to elucidate the 3-D shape of proteins, has simulated a protein transitioning between its inactive and active configurations. Read more...       

Doctors Make Strides Toward HIV Cure, Gene Treatment

March 6, 2014 2:27 pm | by Marilynn Marchione, AP Chief Medical Writer | News | Comments

A second baby born with the AIDS virus may have had her infection put into remission and possibly cured by very early treatment- in this instance, four hours after birth. In other AIDS research, scientists have modified genes in the blood cells of a dozen adults to help them resist HIV. Read more...

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New Probes Quantify Folded and Misfolded Protein Levels in Cells

March 4, 2014 2:29 pm | News | Comments

Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.

G3 Partners with Caprion to Identify Cardiovascular Biomarkers, Targets

February 26, 2014 2:44 pm | News | Comments

Global Genomics Group (G3) and Caprion Proteomics Inc. announced that they have entered into a collaboration agreement to investigate biological networks and pathways in order to discover novel biomarkers and pharmaceutical targets for cardiovascular diseases. Read more...

Computational Models Speed Biomarker Assessment

February 25, 2014 3:20 pm | News | Comments

A research team is working to develop a quicker and less expensive way to evaluate biomarkers, using computational models by sifting through vast medical databases and using engineering assess the most effective predictors of prostate cancer. Read more...

Parkinson’s Biomarker Initiative Expands Study of Genetics

February 25, 2014 2:44 pm | News | Comments

The Parkinson’s Progression Markers Initiative (PPMI), a large-scale biomarker study sponsored by The Michael J. Fox Foundation for Parkinson’s Research (MJFF), is expanding to study individuals with genetic mutations associated with Parkinson’s disease. Read more...

Interferon Research Offers New Hope for Asthma Drugs

February 25, 2014 10:40 am | News | Comments

A new and emerging field in medicine- which involves the study of a group of proteins known as Interferons- could help unlock therapies for a range of diseases, according to new research. Read more...               

New Therapy Targets DNA Tags in Aggressive Brain Cancer

February 21, 2014 10:27 am | News | Comments

Researchers have carried out a comprehensive molecular analysis of ependymoma, an aggressive type of brain cancer that primarily affects infants, and discovered a new way to try and treat these tumors. Read more..          

Genetic Prostate Cancer Advance May Improve Treatments

February 12, 2014 2:46 pm | News | Comments

New findings show how a genetic mutation in untreated terminal prostate cancer patients is linked to aggressive cancer later in life. It was previously thought that the mutation only occurred in response to therapy. Read more...       

New Approach Quickly IDs Drug Candidates from Genome Sequence

February 10, 2014 2:45 pm | News | Comments

In research that could ultimately lead to many new medicines, scientists have developed a potentially general approach to design drugs from genome sequence. Read more...                        

Scientists Create Potential New Vaccine Design

February 6, 2014 10:42 am | News | Comments

Scientists have invented a new method for designing artificial proteins, and have used it to make key ingredients for a candidate vaccine against RSV. Read more...                         

Bladder Cancer Study Reveals Potential Drug Targets

January 29, 2014 2:50 pm | News | Comments

Investigators have identified new potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease. Read more...                   

Opening the Door to New HIV Therapy

January 28, 2014 2:03 pm | News | Comments

Researchers have begun to focused on a new protein, Nef, that hijacks host proteins and is essential to HIV’s lethality. So how will this protein be used as a drug target? Find out...                   

New Hope for Gaucher Disease Target

January 20, 2014 1:52 pm | News | Comments

Scientists have discovered a new cellular pathway implicated in Gaucher disease and their findings may offer a new therapeutic target for the management of this disease, as well as other related disorders. Read more...        

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