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Genomics/Proteomics
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The Lead

Genetic Modification Aids Cancer Drug Discovery

March 4, 2015 3:38 pm | by University of Leuven | News | Comments

Genetically modifying cancer cells can aid in clarifying new cancer drugs’ mechanism of action. Read more...                         

Upending Alzheimer's Theory

March 4, 2015 3:22 pm | by Sue McGreevy, Harvard University | News | Comments

A study reveals exactly how mutations associated with the most common form of inherited...

Scientists Find Clues to Cancer Drug Failures

March 4, 2015 12:35 pm | by Scripps Research Institute | News | Comments

Cancer patients fear the possibility that one day their cells might start rendering many...

Study Shows Who Benefits Most from Statins

March 4, 2015 12:13 pm | by Julia Evangelou Strait, Washington University in St. Louis | News | Comments

New research suggests that widely used statin therapy provides the most benefit to patients with...

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Protein May Be Key to Cancer's Deadly Resurgences

March 3, 2015 4:38 pm | by UCSF | News | Comments

Tumor recurrence following a period of remission is the main cause of death in cancer. The ability of cancer cells to remain dormant during and following therapy, only to be reactivated at a later time, frequently with greater aggressiveness, is one of the least-understood aspects of the disease. Read more...

Gorilla Origins of the Last Two AIDS Virus Lineages Confirmed

March 3, 2015 8:52 am | by University of Pennsylvania | News | Comments

Study has implications for understanding genesis of emerging diseases. Read more...                             

New Nanodevice Defeats Drug Resistance

March 3, 2015 8:46 am | by Anne Trafton, MIT | News | Comments

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. Read more...                     

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J&J Announces Binding Offer from Cardinal Health to Acquire Cordis

March 2, 2015 12:49 pm | News | Comments

The deal breaks down to an aggregate value of $1.99 billion. Read more...

Preventing the Spread of Cancer with Copper Molecules

March 2, 2015 12:43 pm | by Bielefeld University | News | Comments

Chemists have developed a molecule containing copper that binds specifically with DNA and prevents the spread of cancer. Read more...                     

Pancreatic Cancer Subtypes Could Guide Future Treatments

February 27, 2015 8:42 am | by University of Queensland | News | Comments

Scientists have completed the most comprehensive analysis yet of pancreatic cancer, in a study that could improve future treatments. Read more...                   

Scientists Find Cancer Weak Spots for New Targeted Drugs

February 24, 2015 3:15 pm | by University of Sussex | News | Comments

Scientists have identified weak spots in cancer cells that could be targeted and attacked by new precision drugs. Read more...                      

Previously Unknown Effect of Vitamin A Identified

February 24, 2015 3:08 pm | by Lund University | News | Comments

Researchers have identified a previously unknown effect of vitamin A in human embryonic development. Read more...                        

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Researchers Discover Possible Drug Target to Combat Sleeping Sickness

February 24, 2015 8:42 am | by Virginia Tech | News | Comments

Biochemists are trying to deliver a stern wake-up call to the parasite that causes sleeping sickness. Read more...                        

Customized DNA Rings Aid Early Cancer Detection in Mice

February 23, 2015 4:43 pm | by Bruce Goldman, Stanford | News | Comments

Imagine: You pop a pill into your mouth and swallow it. It dissolves, releasing tiny particles that are absorbed and cause only cancerous cells to secrete a specific protein into your bloodstream. Two days from now, a finger-prick blood sample will expose whether you’ve got cancer and even give a rough idea of its extent. Read more...

Garden Hose a Breeding Ground for Legionnaire's Disease

February 23, 2015 9:32 am | by University of New South Wales | News | Comments

It is synonymous with an Aussie summer but the humble backyard hose could be a bacterial breeding ground, providing the ideal conditions for the organisms that cause Legionnaires’ disease to flourish. Read more...        

Large Amounts of Mitochondrial Toxic Agents Cross the Placenta Barrier

February 20, 2015 9:07 am | by Hospital Clinic of Barcelona | News | Comments

Mitochondria can suffer from two types of disease: genetic or acquired. Read more...                             

Researchers Discover Potential Treatment for Drug Resistant TB

February 20, 2015 8:59 am | by University of Georgia | News | Comments

This form of the disease cannot be cured with conventional therapies. Read more...                             

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Cancer Risk Linked to DNA 'Wormholes'

February 20, 2015 8:50 am | by Institute of Cancer Research | News | Comments

Single-letter genetic variations within parts of the genome once dismissed as ‘junk DNA’ can increase cancer risk. Read more...                      

Health Groups Say AIDS No. 1 Killer of Adolescents in Africa

February 18, 2015 3:03 pm | by Tom Odula, Associated Press | News | Comments

Global health organizations said Tuesday that AIDS is now the leading cause of death for adolescents in Africa, and the second leading cause of death among adolescents globally. Read more...            

Taking Technology from the Lab to the Patient

February 18, 2015 10:17 am | by MIT | News | Comments

After finishing his PhD in molecular genetics in the late 1990s, Daniel Anderson found himself conflicted about what to do next: He enjoyed science, but wanted to find a way to have a direct impact on human health. Read more...

Link Between Genetic Switch, Autoimmune Diseases

February 17, 2015 12:53 pm | by NIH | News | Comments

Investigators with the National Institutes of Health have discovered the genomic switches of a blood cell key to regulating the human immune system. The findings, published in Nature, open the door to new research and development in drugs and personalized medicine to help those with autoimmune disorders such as inflammatory bowel disease or rheumatoid arthritis. Read more...

Marvel Molecule Could Lead to Inflammatory Disease Treatments

February 17, 2015 10:13 am | by Trinity College Dublin | News | Comments

Scientists from Trinity College Dublin believe that the marvel molecule — MCC950 — could one day be used to treat a myriad of these diseases. Read more...

Aggressive Form of HIV Uncovered in Cuba

February 13, 2015 4:51 pm | by University of Leuven | News | Comments

Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into a new variant of the virus. Read more...     

Precision Medicine: Why a New Approach is Needed

February 13, 2015 10:49 am | by Columbia University | News | Comments

Precision medicine is a way to make medical care more personalized and individualized. Read more...                           

Scientists Limit Accelerated Cellular Aging Caused by Methamphetamine Use

February 13, 2015 10:41 am | by UC Irvine | News | Comments

The ravaged faces of methamphetamine addicts tell a terrible tale – abusing the drug dramatically accelerates aging. Read more...                      

New Drug Development to Focus on the Genetics of Cervical Cancer

February 13, 2015 8:57 am | by University of Huddersfield | News | Comments

University of Huddersfield researcher Dr Tsitsi Chituku is taking part in a project that seeks to learn more about the genetic factors that make some women more susceptible to cervical cancer.  It was a recent visit to Africa, to carry out a health screening project involving hundreds of women, which helped to shape the emphasis of her research. Read more...

Key to Blocking Flu Virus May Lie in a Cell's Machinery

February 12, 2015 3:35 pm | by Rockefeller University | News | Comments

Viruses are masters of outsourcing, entrusting their fundamental function - reproduction - to the host cells they infect. But it turns out this highly economical approach also creates vulnerability. Read more...                

Scientists Overturn Dogma on Bubonic Plague

February 12, 2015 9:13 am | by University of North Carolina at Chapel Hill | News | Comments

For decades, scientists have thought the bacteria that cause the bubonic plague hijack host cells at the site of a fleabite and are then taken to the lymph nodes. Read more...              

Sequence of Genetic Mutations Determine How Cancer Behaves

February 12, 2015 9:01 am | by University of Cambridge | News | Comments

Researchers show for the first time that the order in which such mutations occur can have an impact on disease severity and response to therapy. Read more...                 

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