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Daily news and top headlines for drug research professionals

Cancer Risk Linked to DNA 'Wormholes'

February 20, 2015 8:50 am | by Institute of Cancer Research | News | Comments

Single-letter genetic variations within parts of the genome once dismissed as ‘junk DNA’ can increase cancer risk. Read more...                      

Health Groups Say AIDS No. 1 Killer of Adolescents in Africa

February 18, 2015 3:03 pm | by Tom Odula, Associated Press | News | Comments

Global health organizations said Tuesday that AIDS is now the leading cause of death for adolescents in Africa, and the second leading cause of death among adolescents globally. Read more...            

Taking Technology from the Lab to the Patient

February 18, 2015 10:17 am | by MIT | News | Comments

After finishing his PhD in molecular genetics in the late 1990s, Daniel Anderson found himself conflicted about what to do next: He enjoyed science, but wanted to find a way to have a direct impact on human health. Read more...

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Link Between Genetic Switch, Autoimmune Diseases

February 17, 2015 12:53 pm | by NIH | News | Comments

Investigators with the National Institutes of Health have discovered the genomic switches of a blood cell key to regulating the human immune system. The findings, published in Nature, open the door to new research and development in drugs and personalized medicine to help those with autoimmune disorders such as inflammatory bowel disease or rheumatoid arthritis. Read more...

Marvel Molecule Could Lead to Inflammatory Disease Treatments

February 17, 2015 10:13 am | by Trinity College Dublin | News | Comments

Scientists from Trinity College Dublin believe that the marvel molecule — MCC950 — could one day be used to treat a myriad of these diseases. Read more...

Aggressive Form of HIV Uncovered in Cuba

February 13, 2015 4:51 pm | by University of Leuven | News | Comments

Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into a new variant of the virus. Read more...     

Precision Medicine: Why a New Approach is Needed

February 13, 2015 10:49 am | by Columbia University | News | Comments

Precision medicine is a way to make medical care more personalized and individualized. Read more...                           

Scientists Limit Accelerated Cellular Aging Caused by Methamphetamine Use

February 13, 2015 10:41 am | by UC Irvine | News | Comments

The ravaged faces of methamphetamine addicts tell a terrible tale – abusing the drug dramatically accelerates aging. Read more...                      

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New Drug Development to Focus on the Genetics of Cervical Cancer

February 13, 2015 8:57 am | by University of Huddersfield | News | Comments

University of Huddersfield researcher Dr Tsitsi Chituku is taking part in a project that seeks to learn more about the genetic factors that make some women more susceptible to cervical cancer.  It was a recent visit to Africa, to carry out a health screening project involving hundreds of women, which helped to shape the emphasis of her research. Read more...

Key to Blocking Flu Virus May Lie in a Cell's Machinery

February 12, 2015 3:35 pm | by Rockefeller University | News | Comments

Viruses are masters of outsourcing, entrusting their fundamental function - reproduction - to the host cells they infect. But it turns out this highly economical approach also creates vulnerability. Read more...                

Scientists Overturn Dogma on Bubonic Plague

February 12, 2015 9:13 am | by University of North Carolina at Chapel Hill | News | Comments

For decades, scientists have thought the bacteria that cause the bubonic plague hijack host cells at the site of a fleabite and are then taken to the lymph nodes. Read more...              

Sequence of Genetic Mutations Determine How Cancer Behaves

February 12, 2015 9:01 am | by University of Cambridge | News | Comments

Researchers show for the first time that the order in which such mutations occur can have an impact on disease severity and response to therapy. Read more...                 

Heating Targeted Cancer Drugs Increases Uptake in Tumor Cells

February 11, 2015 9:37 am | by University of Manchester | News | Comments

One of the clinically-established methods for the delivery of cancer chemotherapy drugs has been to package the drug inside nano-sized containers, known as liposomes. Read more...              

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Computer Model of Blood Development Could Speed Up Search for New Leukemia Drugs

February 11, 2015 9:13 am | by University of Cambridge | News | Comments

 The human body produces over 2.5 million new blood cells during every second of our adult lives, but how this process is controlled remains poorly understood. Read more...              

Engineered Insulin Could Offer Better Diabetes Control

February 10, 2015 11:58 am | by Anne Trafton, MIT | News | Comments

Engineers hope to improve treatment for diabetes patients with a new type of engineered insulin. Read more...                         

Engineered Insulin Could Offer Better Diabetes Control

February 10, 2015 11:58 am | by Anne Trafton, MIT | News | Comments

Engineers hope to improve treatment for diabetes patients with a new type of engineered insulin. Read more...                         

Study Shows Why Some Targeted Cancer Drugs Lose Effectiveness

February 10, 2015 11:53 am | by Pete Farley, UCSF | News | Comments

A protein plays a key role in the emergence of resistance to targeted cancer therapies. Read more..                            

CDK4/6 Inhibitor: Promising Results for Treating Breast Cancer

February 9, 2015 1:06 pm | by Drug Discovery & Development staff | Articles | Comments

The words “exciting,” “breakthrough,” and “standard-of-care-changing” are being used with regard to cyclin-dependent kinase (CDK) 4 and 6 inhibitors and metastatic breast cancer. Read more...                                       

A Look at Some Vaccine-Related Legislation in Several States

February 6, 2015 4:07 pm | by Associated Press | News | Comments

Several state legislatures are debating vaccine-related measures as dozens of people have fallen ill from a measles outbreak that started at Disneyland in December and spread beyond the theme park. Here is a look at some of the legislation around the country. Read more...

Blue Waters Project Helps Uncover Alzheimer's Genetic Networks

February 6, 2015 1:51 pm | by NSF | News | Comments

There are several drugs on the market that can provide relief from Alzheimer's symptoms, but none stop the development of disease, in part because the root causes of Alzheimer's are still unclear. Read more...                

Reversing the Global Diabesity Epidemic

February 6, 2015 1:42 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Articles | Comments

Diabesity has been identified as a major global health problem by researchers and healthcare professionals world-wide, including England’s National Health Service, Brigham and Women’s Hospital and Harvard Medical School, Ain Shams University Hospital in Cairo, Egypt, and a research consortium of the European Union. Read more...

Getting Ahead of Antibiotic Resistant Bacteria

February 6, 2015 9:01 am | by Colin Poitras, University of Connecticut | News | Comments

The prevalence of antibiotic-resistant bacteria has turned new drug development into a high-stakes chess game, with researchers always trying to anticipate a disease bacteria’s next move or mutation. Read more...        

Diamonds Could Help Bring Proteins into Focus

February 6, 2015 8:56 am | by David L. Chandler - MIT | News | Comments

A new technique shows great promise for producing highly detailed images of individual proteins. Read more...                         

New Biomarkers to Spot Pancreatic Cancer Early

February 5, 2015 3:37 pm | by University College London | News | Comments

Pancreatic cancer could be diagnosed up to two years earlier by screening for two tumor markers found in blood. Read more...                       

New Source of Cells for Modeling Malaria

February 5, 2015 3:25 pm | by Anne Trafton, MIT | News | Comments

Scientists are trying to develop new drugs that target the malaria parasite during the stage when it infects the human liver, which is crucial because some strains of malaria can lie dormant in the liver for several years before flaring up. Read more...  

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