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Daily news and top headlines for drug research professionals

Gene Variant Linked to Cancer

April 17, 2015 8:11 am | by Washington University in St. Louis | News | Comments

Smokers with a specific genetic variation are more likely to keep smoking longer than those who don’t have the gene variant. Read more...

Scientists Discover Protein That Boosts Immunity to Viruses and Cancer

April 17, 2015 8:10 am | by Imperial College London | News | Comments

Scientists have discovered a protein that plays a central role in promoting immunity to viruses and cancer, opening the door to new therapies. Read more...

Tumor-Only Genetic Sequencing May Mislead Cancer Therapy

April 15, 2015 2:03 pm | by Stephanie Guzowski, Editor | News | Comments

When it comes to sequencing patients’ tumor genomes to personalize cancer therapy, one very important step may be missing, suggest Johns Hopkins researchers: a point of comparison to patients’ noncancerous genomes. Read more...


How Molecule Protects Brain Cells in Parkinson’s Disease Model

April 15, 2015 11:35 am | by Scripps Research Institute | News | Comments

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found how a widely known but little-studied enzyme protects brain cells in models of Parkinson’s disease. Read more...

Heart Metabolics, FDA Agree on Special Protocol Assessment for Perhexiline Single Phase 3 Trial

April 15, 2015 9:23 am | News | Comments

The FDA has agreed to a single, randomized, pivotal Phase 3 trial of 350 patients evaluating perhexiline for the treatment of moderate-to-severe HCM. Read more...

Scientific Breakthrough Unlocks Potential Novel Tendon Therapy

April 14, 2015 11:00 am | by University of Glasgow | News | Comments

Scientists are investigating a new therapy for the treatment of tendon injuries such as tennis elbow and Achilles tendinitis after gaining new insight into the condition. Read more..

Central Signaling Pathway in Lymphoma Blocked Successfully

April 14, 2015 8:19 am | by University of Zurich | News | Comments

Cancer researchers from the University of Zurich have identified a key signaling pathway in B-cell lymphoma, a malignant type of blood cancer. Read more...

Eisai, Genomics Plc to Team Up on Large Scale Genotype/Phenotype Data Analysis Project

April 14, 2015 8:18 am | News | Comments

Both companies believe that human genetics and genomics can add great value to the drug development process. Read more...


NIH, South African Medical Research Council Award $8M in HIV, TB Grants

April 14, 2015 8:17 am | by National Institutes of Health | News | Comments

The National Institutes of Health and the South African Medical Research Council (SAMRC) are awarding 31 grants to U.S. and South African scientists to support research targeting HIV/AIDS, tuberculosis and HIV-related co-morbidities and cancers. Read more...

New Way to Fight Cancer

April 14, 2015 8:17 am | by Harvard University | News | Comments

Targeted cancer therapies work by blocking a single oncogenic pathway to halt tumor growth. Read more...

Coffee Protects DNA From Breaking, Say Two Recent Studies

April 13, 2015 3:47 pm | by Drug Discovery & Development Staff | Articles | Comments

Coffee drinking is often associated with lower rates of degenerative diseases, from Parkinson’s to cancers. Two recent studies support one theory why: coffee protects DNA from breaking, and quite shortly after it is consumed.

First Look at 'Wasabi Receptor' Brings Insight for Pain Drug Development

April 10, 2015 10:51 am | by Peter Farley, UCSF | News | Comments

Protein’s structure will guide hunt for new treatments of inflammation-induced pain. Read more...

Cellular Defect Linked to Diabetes

April 9, 2015 12:33 pm | by Columbia University | News | Comments

A cellular defect that can impair the body’s ability to handle high glucose levels and could point the way to a potential new treatment for diabetes has been identified by Columbia University Medical Center (CUMC) researchers. Read more..


Researchers Deliver Large Particles into Cells at High Speed

April 9, 2015 12:27 pm | by UCLA | News | Comments

A new device developed by UCLA engineers and doctors may eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research. Read more...

The First Personalized Genomic Cancer Vaccines

April 9, 2015 12:07 pm | by Cynthia Fox, Science Writer | Articles | Comments

The first personalized cancer vaccine using genomics to define targets elicits robust immune responses, says a recent Science study. Read more...

World-First Human Hendra Virus Clinical Trials Begin

April 8, 2015 8:23 am | by University of Queensland | News | Comments

An antibody manufactured at The University of Queensland will be used in world-first human Hendra virus clinical trials starting this month. Read more...

Body's Cancer Defenses Hijacked to Make Pancreatic and Lung Cancer More Aggressive

April 8, 2015 8:22 am | by Cancer Research UK | News | Comments

Scientists have discovered that a vital self-destruct switch in cells is hijacked - making some pancreatic and non small cell lung cancers more aggressive. Read more...

Scientists Identify Receptor for Asthma Associated Virus

April 6, 2015 5:01 pm | by National Institute of Allergy and Infectious Disease | News | Comments

Scientists have identified a cellular receptor for rhinovirus C. Read more...

Study Suggests New Role for Gene in Suppressing Cancer

April 6, 2015 4:37 pm | by University of Manchester | News | Comments

Scientists have discovered that a previously known gene also helps cells divide normally and that its absence can cause tumors. Read more...

Cancer Drug Target also Essential for Blood Cell Recovery

April 6, 2015 4:26 pm | by Walter & Eliza Hall Institute of Medical Research | News | Comments

Blocking key survival proteins is a promising tactic for treating cancer, however new research suggests care should be taken as these proteins are also vital for emergency blood cell production. Read more...

New Developments in Characterizing Protein-Small Molecule Interactions for Drug Discovery

April 6, 2015 4:26 pm | by Bill Sawka, MicroCal Product Manager, Malvern Instruments & Natalia Markova, Principal Scientist – MicroCal, Malvern Instruments | Articles | Comments

Isothermal titration calorimetry (ITC) is a highly valuable technique that is used throughout drug discovery workflow to study the binding interactions of proteins and small molecules. It is an essential tool for both drug design and the study and regulation of protein interactions. Read more...

From the Heart

April 6, 2015 9:53 am | by Anne Trafton, MIT | News | Comments

​Laurie Boyer’s studies of stem cell differentiation could improve treatments for heart disease. Read more...

Personalized Melanoma Vaccines Marshal Immune Response

April 6, 2015 9:49 am | by Washington University in St. Louis | News | Comments

Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients’ tumors, according to early data in a first-in-people clinical trial at Washington University School of Medicine in St. Louis. Read more...

Imported Drug-Resistant Stomach Bug Spreading in U.S.

April 6, 2015 8:16 am | by Mike Stobbe, AP Medical Writer | News | Comments

A drug-resistant strain of a nasty stomach bug made its way into the U.S. and spread, causing more than 200 illnesses since last May. Read more...

New Sickle Cell Gene Therapy Approaches

April 2, 2015 11:21 am | by Cynthia Fox, Science Writer | Articles | Comments

As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cell disease, two top scientists are already improving the approach. Read more...

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