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Genomics/Proteomics
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Daily news and top headlines for drug research professionals

HIV Replicates in Brain Earlier than Thought: Study

March 26, 2015 2:05 pm | by Stephanie Guzowski, Editor | News | Comments

A recent study, funded by the National Institutes of Health (NIH), highlights the importance of HIV screening and beginning antiretroviral therapy (ART) as early as possible. The analysis of cerebral spinal fluid (CSF), which illuminates brain chemical activity, showed that HIV can begin replicating in a patient’s brain as early as four months after infection. Read more...

New Autism-Causing Genetic Variant Identified

March 26, 2015 1:35 pm | by Johns Hopkins | News | Comments

Using a novel approach that homes in on rare families severely affected by autism, a Johns Hopkins-led team of researchers has identified a new genetic cause of the disease. Read more...

Study Announces Durable Ebola Vaccine

March 25, 2015 2:10 pm | by Andrew Gould, University of Plymouth | News | Comments

A new study shows the durability of a novel CMV-based Ebola virus vaccine strategy that may eventually have the potential to reduce ebola virus infection in wild African ape species. Read more...

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Potential for ALS Treatment Found in Three Proteins

March 25, 2015 8:17 am | by David Callahan, KTH Royal Institute of Technology | News | Comments

Recent research at Sweden's KTH Royal Institute of Technology has found three proteins that could shed some light on the mechanisms behind ALS. Read more...

Enzyme that Helps Prevent Anemia: Discovery

March 24, 2015 12:19 pm | by Scripps Research Institute | News | Comments

​Stem cells can generate any type of cell in the body, but they are inactive most of the time—and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations. Read more...

Blood Thinning Drug Aids Understanding of Natural HIV Barrier

March 24, 2015 8:50 am | by University of East Anglia | News | Comments

A blood thinning agent is helping researchers understand more about the body’s natural barriers to HIV. Read more...

Scientists Use DNA Sequencing to Trace Spread of Drug Resistant TB

March 24, 2015 8:45 am | by Sam Wong, Imperial College London | News | Comments

Scientists have for the first time used DNA sequencing to trace the fatal spread of multidrug-resistant tuberculosis between patients in the UK. Read more...

Mutated Gene Increases Insulin Resistance

March 24, 2015 8:31 am | by Becky Bach, Stanford University | News | Comments

An international team of researchers at the Stanford has discovered a gene that, when mutated, increases insulin resistance. Read more...

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New Test to Revolutionize Disease Detection in People, Crops, and Stock

March 23, 2015 8:43 am | by University of Queensland | News | Comments

A single-drop DNA test invented by scientists could revolutionize the detection of diseases in humans, livestock and crops. Read more...

NSAIDS and Cancer Risk

March 20, 2015 10:01 am | by Sue McGreevy, Harvard University | News | Comments

An analysis of genetic and lifestyle data from 10 large epidemiologic studies has confirmed that regular use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to reduce the risk of colorectal cancer in most individuals. Read more...

World-First Cancer Drugs Could Work in Larger Group of Patients

March 19, 2015 4:22 pm | by Institute of Cancer Research | News | Comments

A pioneering class of drugs that target cancers with mutations in the BRCA breast cancer genes could also work against tumors with another type of genetic fault. Read more...

Stem Cells Show Promise for Reversing Type 2 Diabetes

March 19, 2015 4:15 pm | by University of British Columbia | News | Comments

Scientists have shown for the first time that Type 2 diabetes can be effectively treated with a combination of specially-cultured stem cells and conventional diabetes drugs. Read more...

Study Sheds New Light on Asthma, COPD

March 19, 2015 1:08 pm | by Julia Evangelou Strait, Washington University in St. Louis | News | Comments

In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production. Read more...

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Capturing the Living Picture of Cancer: Proteomic Testing in the Clinical Lab

March 19, 2015 12:46 pm | by Richard Hockett, M.D., Chief Medical Officer at Biodesix, a molecular diagnostics company | Articles | Comments

If genetic sequencing provides the script of life, then proteomics is the live video capturing biology in action. Proteomics moves beyond the static information provided by genomics and tells the story in real-time of proteins, which result from the individual genes within a cell. Read more...

Antibiotic Nanoparticles Attack Respiratory Infection

March 19, 2015 9:11 am | by Helmholtz Centre for Infection Research | News | Comments

Treating respiratory disease is often difficult because drugs have to cross biological barriers such as respiratory tissue and mucosa, and must therefore be given in large quantities in order for an effective amount to reach the target. Read more...

3-D Protein Snapshot Highlights Potential Drug Target for Breast Cancer

March 18, 2015 11:18 am | by University of Vermont | News | Comments

The genome of a cell is under constant attack, suffering DNA damage that requires an army of repair mechanisms to keep the cell healthy and alive. Understanding the behavior of the enzymes defending these assaults helps determine how - and where - cancer gets its foothold and flourishes. Read more...

Where is the Money in Biosimilars?

March 18, 2015 9:11 am | by Daniel N. Galbraith, Ph.D., BioOutsource Ltd | Articles | Comments

In the past 10 years biosimilars have held strong in the biologics industry’s headlines. These products were once thought impossible to approve in regulated markets because the sheer complexity of producing these large, complex proteins can result in “robustness” issues. Read more...

Potential Drug Target Found to Prevent Bowel Cancer Spread

March 18, 2015 9:03 am | by Monash University | News | Comments

Scientists have discovered a molecule that is crucial to the survival of stem cells in the intestine. Read more...

Emerging Diseases Likely to be More Harmful in Similar Species

March 18, 2015 8:49 am | by University of Cambridge | News | Comments

Research shows that it may be possible to predict the virulence of a virus by looking at how deadly it is in closely-related species. Read more...

23andMe FDA Approval Clears Way for More Sequencing-Based Tests

March 17, 2015 12:17 pm | News | Comments

​Kalorama information suggests that the FDA approval of a rare gene test from Mountain View, Calif.-based personal genetics company 23andMe will open the way for more genetic tests sold to consumers or prescribed by doctors that use next-generation sequencing technology. Read more...

Gene Discovery Provides Clue to How TB May Evade the Immune System

March 17, 2015 9:01 am | by University of Cambridge | News | Comments

The largest genetic study of tuberculosis susceptibility to date has led to a potentially important new insight into how the pathogen manages to evade the immune system. Read more...

Scientists Make Surprise Finding in Stroke Research

March 17, 2015 8:37 am | by University of Manchester | News | Comments

Scientists have made an important new discovery about the brain’s immune system that could lead to potential new treatments for stroke and other related conditions. Read more...

Antibody Therapy Dramatically Improves Psoriasis Symptoms

March 16, 2015 8:28 am | by Rockefeller University | News | Comments

Many patients suffering from psoriasis showed significant recovery during clinical trials. Read more...

Genetic Test Maker 23AndMe Launches Drug R&D Effort

March 12, 2015 1:45 pm | by Matthew Perrone, Associated Press | News | Comments

Google-backed genetic testing company 23andMe is launching its own drug development unit, betting that it can translate its database of customer DNA information into novel medicines. Read more...                      

Researchers Uncover New Way the Body Fine Tunes Immune Response

March 12, 2015 9:46 am | by University of British | News | Comments

The findings could inform vaccine design, and may explain the molecular basis for certain autoimmune diseases and B cell malignancies. Read more...                                                                                                         

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