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Synthesis Produces New Antibiotic

August 29, 2014 2:00 pm | News | Comments

A  collaboration at Rice University has led to the total synthesis of a recently discovered natural antibiotic. The laboratory recreation of a fungus-derived antibiotic, viridicatumtoxin B, may someday help bolster the fight against bacteria that evolve resistance to treatments in hospitals and clinics around the world. Read more...

An End to Drug Errors?

August 29, 2014 8:30 am | News | Comments

MIT alumni have devised the MedEye, a bedside medication-scanning system that uses computer...

Compound Promises Relief for Inflammatory Pain

August 28, 2014 2:00 pm | News | Comments

Researchers have discovered that a compound they developed could potentially serve as a...

HIV Drug Dosage May Be Ineffective for African-Americans

August 28, 2014 2:00 pm | News | Comments

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study...

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UN: Ebola Cases Could Reach 20,000

August 28, 2014 9:34 am | by John Heilprin and Krista Larson | News | Comments

The Ebola outbreak in West Africa eventually could exceed 20,000 cases, more than six times as many as are now known, the World Health Organization said Thursday. Read more...                      

Marijuana Compound May Slow, Halt Alzheimer’s

August 27, 2014 3:00 pm | News | Comments

Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer’s disease, a new study says. Read more...                   

Compound Suppresses Binge Eating in Mice

August 27, 2014 2:26 pm | News | Comments

Researchers found that the hormone estrogen can specifically trigger brain serotonin neurons to inhibit binge eating, which affects about 5 to 10 percent of U.S. adults, in female mice. Read more...               

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3rd Doctor Dies from Ebola in Sierra Leone

August 27, 2014 10:27 am | by Clarence Roy-Macaulay | News | Comments

A third top doctor has died from Ebola in Sierra Leone, a government official said Wednesday, as health workers tried to determine how a fourth scientist also contracted the disease before being evacuated to Europe. Read more...       

Japan Lab Unable to Replicate Stem Cell Results

August 27, 2014 10:22 am | by Elaine Kurtenbach, AP Business Writer | News | Comments

The Japanese laboratory that retracted a paper reporting a potentially major breakthrough in stem cell research said Wednesday its researchers have not managed to replicate the results. Read more...               

Protein Family Can Inhibit HIV Release

August 26, 2014 10:30 am | News | Comments

A family of proteins that promotes virus entry into cells also has the ability to block the release of HIV and other viruses, researchers have found. Read more...                         

US Health Official: Ebola Has 'Upper Hand'

August 26, 2014 10:14 am | by Jonathan Paye-Layleh | News | Comments

The Ebola virus has the "upper hand" in an outbreak that has killed more than 1,400 people in West Africa, a top American health official said, adding that experts have the tools to stop it. Read more...             

‘The Pill’ Shrinks Ovaries, Cuts Egg Numbers

August 25, 2014 9:49 am | by Cynthia Fox, Science Editor | Articles | Comments

The birth control pill significantly affects ovarian reserve— or the number of immature eggs in a woman’s ovaries— which can be a predictor of future fertility, according to a team in Denmark. Read more...             

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Some Anti-Inflammatory Drugs Affect More Than Their Targets

August 22, 2014 3:41 pm | News | Comments

Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Read more...                       

Pomegranate-Based Drug May Stem Alzheimer’s, Parkinson’s

August 22, 2014 3:31 pm | News | Comments

The onset of Alzheimer’s disease can be slowed and some of its symptoms curbed by a natural compound that is found in pomegranate, according to new findings. Read more...                        

Mutated Polio Virus Breaches Vaccine Protection

August 22, 2014 10:48 am | News | Comments

Scientists of the University of Bonn, together with colleagues from Gabon, are reporting alarming findings: a mutated polio virus that was able to resist the vaccine protection to a considerable extent was found in victims of an outbreak in the Congo in 2010. Read more...

The Case for Orphan Drugs

August 22, 2014 10:34 am | by Louise Rozik, Editor | Articles | Comments

Neglected by the pharmaceutical industry before the Orphan Drug Act of 1983, rare diseases are now front and center in pharma R&D, with approximately one-third of all new medicines approved by the FDA in the past 5 years having been developed for the treatment of diseases that affect fewer than 200,000 Americans. Read more...

Botox Injections Slow Growth of Stomach Tumors

August 21, 2014 1:00 pm | News | Comments

New research shows that nerves may play a critical role in stomach cancer growth and that blocking nerve signals using Botox (onabotulinumtoxinA) could be an effective treatment for the disease. Read more...             

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Researchers Restore Protein in Muscular Dystrophy

August 21, 2014 11:19 am | News | Comments

For the first time, a research team has succeeded in restoring a missing repair protein in skeletal muscle of three patients with muscular dystrophy carrying a dysferlin mutation who received a single systemic dose of a proteasome inhibitor. Read more...

Ebola: Slum Calm; Aid Worker Recovers

August 21, 2014 11:12 am | by Jonathan Paye-Layleh, Associated Press | News | Comments

Calm returned Thursday to a slum in the Liberian capital that was sealed off in the government's attempt to halt the spread of Ebola, a day after clashes erupted between residents and security forces, and in the United States, an aid worker who was infected in Liberia has recovered. Read more...

New Vaccine Promising Weapon Against TB, Leprosy

August 20, 2014 2:09 pm | News | Comments

The currently available century-old vaccine Bacille Calmette-Guerin, or BCG, provides only partial protection against both tuberculosis and leprosy. Now, researchers may have found a stronger weapon against both diseases. Read more...     

Liberia Seals Slum to Halt Ebola

August 20, 2014 10:09 am | by Jonathan Paye-Layleh, Abbas Dulleh, Associated Press | News | Comments

Security forces blocked off a seaside slum in Liberia's capital Wednesday, stepping up the government's fight to stop the spread of Ebola, unnerving residents and reportedly sparking a protest by disgruntled youths opposed to the quarantine. Read more...

Unlocking the Power of Big Data in R&D, Part Two

August 19, 2014 11:23 am | by Sharon Benzeno, PhD, MBA, Senior Director, Business Development Bioinformatics, Elsevier | Articles | Comments

Big data is one of the hottest topics in R&D as its potential to accelerate successful drug development becomes more widely recognized. Part 2 of this two-part article analyses the new data-driven decision-making approaches make a difference to life science R&D. Read more...

Breaking News: All Missing Ebola Patients Are Back

August 19, 2014 10:16 am | by Jonathan Paye-Layleh, John Heilprin, Associated Press | News | Comments

All the people who were being screened for Ebola when they fled a health center during looting are now back in a hospital, a Liberian official said Tuesda, but it is still not clear where the stolen bloody sheets and mattresses are. Read more...

Microchip Tracks Cancer Cell Migration

August 18, 2014 10:50 am | News | Comments

Using a microengineered device that acts as an obstacle course for cells that leaves just enough space for the cells to weave their way through, researchers have shed new light on a cellular metamorphosis thought to play a role in tumor cell invasion throughout the body. Read more...

Ebola Quarantine Escapees Return

August 18, 2014 10:39 am | by Jonathan Paye-Layleh, Associated Press | News | Comments

Some of the people who fled an Ebola quarantine center in a Liberian slum when it was looted over the weekend are again under observation at a hospital Monday, as authorities struggle to contain the spread of an Ebola outbreak in West Africa. Read more...

Watch Yourself: Device Data May Improve Parkinson's Research, Monitoring

August 15, 2014 2:01 pm | Videos | Comments

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and Intel Corporation announced a collaboration aimed at improving research and treatment for Parkinson’s disease. Read more...                  

10 Things You Might Not Know About Ebola

August 15, 2014 1:09 pm | by Christina Jakubowski, News Editor | News | Comments

The 2014 outbreak of Ebola virus in West Africa has the world on high alert. Currently deemed an international public health emergency by the WHO, the virus has racked up more than 1,060 deaths and sickened 1,975 – making it the deadliest Ebola outbreak ever.

HIV Patients in Developing Countries Face New Health Threats

August 15, 2014 10:11 am | News | Comments

Health care systems that keep HIV patients from dying early in low- and middle-income nations need urgently to be repurposed to treat the chronic diseases that many of these patients now have, according to recommendations resulting from a multidisciplinary conference sponsored by the National Institutes of Health. Read more...

Chikungunya Vaccine Induces Robust Antibody Response

August 15, 2014 9:55 am | News | Comments

An experimental vaccine to prevent the mosquito-borne viral illness chikungunya elicited neutralizing antibodies in all 25 adult volunteers who participated in a recent early-stage clinical trial conducted by researchers at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. Read more...

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