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The Lead

Pre-Empting Flu Evolution May Make Better Vaccines

November 21, 2014 9:37 am | News | Comments

An international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by ‘pre-empting’ the evolution of the influenza virus. Read more...           

Breakthrough Found to Help Manage Yellow Fever

November 21, 2014 9:24 am | News | Comments

Yellow fever is a disease that can result in symptoms ranging from fever to severe liver damage...

New Approach for Treating ALS

November 20, 2014 1:45 pm | News | Comments

Researchers show that the brain’s machinery for pumping out toxins is ratcheted up in ALS...

Global Obesity Costs Hits $2 Trillion

November 20, 2014 12:35 pm | by Danica Kirka - Associated Press | News | Comments

The global cost of obesity has risen to to nearly as much as smoking or the combined aspect of...

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Virus Discovery Could Impact HIV Drug Research

November 20, 2014 12:23 pm | News | Comments

A research team has unlocked the structure of an unusual virus that lives in volcanic hot springs. Read more...                         

Promising One-Two Punch for Lung Cancer

November 20, 2014 10:19 am | News | Comments

Scientists at the Salk Institute have discovered a powerful one-two punch for countering a common genetic mutation that often leads to drug-resistant cancers. The dual-drug therapy–with analogs already in use for other diseases–doubled the survival rate of mice with lung cancer and halted cancer in pancreatic cells. Read more...

Bacterial Infections Suppress Immune Response in Neurodermatitis

November 20, 2014 9:31 am | by Technische Universität München | News | Comments

The skin condition neurodermatitis affects nearly one in four children and also occurs frequently in adults. Many patients also develop infections in the dry, open patches of skin, for example due to colonization by the pathogenic bacterium Staphylococcus aureus, which is particularly abundant on the skin of neurodermatitis patients. Read more...

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Chemical Disguise Transforms RNAi Drug Delivery

November 19, 2014 1:04 pm | News | Comments

Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery — it is extremely difficult to get RNAi drugs inside the cells in which they are needed.  Read more...

Light-Responding Blood Vessel Receptor May Be New Target

November 19, 2014 12:46 pm | by Johns Hopkins | News | Comments

A team of researchers from Johns Hopkins Medicine has discovered a receptor on blood vessels that causes the vessel to relax in response to light, making it potentially useful in treating vascular diseases. In addition, researchers discovered a previously unknown mechanism by which blood vessel function is regulated through light of a specific wavelength. Read more...

Maximizing the Power of Preclinical Cancer Research Tools

November 19, 2014 11:29 am | by Guizhong Liu, Senior Director of Cancer Biology, Crown Bioscience Inc. | Articles | Comments

Drug discovery is a protracted and uncertain process that needs to overcome many hurdles during preclinical and clinical development before it finally achieves regulatory approval for patient treatment. For every drug that reaches the marketplace, well over 100 have been abandoned at some point in their development. Read more...

New Laser Therapy Helps Slow Macular Degeneration

November 19, 2014 9:36 am | News | Comments

This new faster laser did not result in damage to the retina. Read more...                               

Sub-Standard Meds Flood Afghan Market

November 19, 2014 9:24 am | News | Comments

Up to 300 companies in Pakistan produce poor quality drugs exclusively for Afghanistan because their products do not meet Pakistani government standards. Read more...                

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Study Will Test Survivors' Blood to Treat Ebola

November 19, 2014 9:19 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Plasma from survivors contains antibodies, substances the immune system makes to fight the virus. Read more...                         

New Insight Into Cells Could Lead to Better Drugs

November 19, 2014 9:11 am | News | Comments

Researchers investigated how different types of immune cells communicate with each other – and how they kill cancerous or infected cells. Read more...                   

Reprogramming Cells, Long Term

November 18, 2014 2:07 pm | by B. D. Colen, Harvard Staff Writer | News | Comments

Harvard Stem Cell Institute (HSCI) researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology (MIT), have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period. Read more...

‘Big Data’ Approach to Help Pinpoint New Stent Drug

November 18, 2014 1:40 pm | by Tracie White, Stanford University | News | Comments

Replacing the current drug used to coat artery-opening stents with a drug more targeted to the actual cause of stent disease could reduce blood clots and heart attacks, researchers say. Read more...

Society for Neuroscience Annual Meeting Showcases Strides in Exploring the Brain

November 18, 2014 10:56 am | by Christina Jakubowski, Managing Editor, Bioscience Technology | Articles | Comments

More than 30,000 brain advocates from academia, industry and media converged on Washington, D.C. this week for the 44th annual meeting of the Society for Neuroscience (SfN). Read more...

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Journal Watch: Top 100 Cited Papers of All Time

November 18, 2014 9:52 am | by Drug Discovery & Development Staff | Articles | Comments

In honor of the SCI’s 50th anniversary, the journal Nature asked Thomson Reuters for the 100 most highly cited papers of all time.  Read more...                                  

Roche Announces FDA Approval of Ovarian Cancer Treatment

November 17, 2014 1:30 pm | News | Comments

The FDA approves Roche's ovarian cancer treatment. Read more...                                 

Method Developed for Detecting Tumor-Causing Mutations in Saliva

November 17, 2014 1:18 pm | News | Comments

Current methods to screen for lung cancer mutations in plasma or blood are complicated, technique-dependent and not readily available. Read more...                   

Statins Reverse Learning Disabilities Caused By Genetic Disorder

November 17, 2014 1:08 pm | News | Comments

Scientists have discovered that statins reverse the learning disabilities caused by a genetic disorder. Read more...                        

Genzyme's MS Drug Gains FDA Approval

November 17, 2014 12:56 pm | News | Comments

The FDA approved Genzyme's new drug for the treatment of multiple sclerosis. Read more...                             

DEA Agents Raid NFL Medical Staffs After Games

November 17, 2014 12:39 pm | by Jim Litke - AP Sports Writer | News | Comments

The DEA investigation comes during a turbulent time for the NFL. Read more...                               

Study Lifts Cloud Over Heart Drugs

November 17, 2014 12:25 pm | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

A major study lifts a cloud around blockbuster drugs for lowering cholesterol. Read more...                             

Nebraska Hospital: Surgeon With Ebola Has Died

November 17, 2014 10:03 am | by Nelson Lampe - Associated Press | News | Comments

A surgeon who contracted Ebola in his native Sierra Leone died Monday while being treated in a biocontainment unit at a Nebraska hospital. Read more...                   

A New Approach to Fighting Leukemia

November 17, 2014 9:50 am | News | Comments

Leukemia treatments are often limited by the fact that the cancer cells can adapt to resist drugs. Read more...                         

Beta Blockers Could Benefit Patients With HFPEF

November 17, 2014 9:29 am | News | Comments

A new study suggests that beta blockers may benefit patients suffering from a relatively unknown form of heart failure. Read more...                      

Going Purple: 5 Cutting-edge Breakthroughs in Alzheimer’s Research

November 17, 2014 9:03 am | by Christina Jakubowski, Managing Editor, Bioscience Technology | Articles | Comments

November is already halfway over— which means we’re also halfway through National Alzheimer's Disease Awareness Month, which celebrates and raises awareness for the nearly 5.4 million people who have this condition. Read more...

Tiny Needles Could Treat Two Major Eye Diseases

November 14, 2014 1:09 pm | by John Toon, Georgia Institute of Technology | News | Comments

Needles almost too small to be seen with the unaided eye could be the basis for new treatment options for two of the world’s leading eye diseases: glaucoma and corneal neovascularization. Read more...

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