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The Lead

Chinese-Built Ebola Center Dedicated in Liberia

November 26, 2014 12:00 pm | by Jonathan Paye-Layleh and Clarence Roy-Macaulay, Associated Press | News | Comments

China, one of the first countries to send aid to battle Ebola in West Africa, ramped up the assistance significantly Tuesday by opening a 100-bed treatment center in Liberia as rows of uniformed Chinese army medics stood at attention.      

A Hybrid Vehicle That Delivers DNA

November 26, 2014 12:00 pm | News | Comments

A new hybrid vehicle is under development. Its performance isn’t measured by the distance it...

A Reason to be Thankful: Turkeys May be Lifesavers

November 26, 2014 12:00 pm | News | Comments

While the turkey you eat on Thursday will bring...

C3BS Nominates Investigators for Clinical Trial of Heart Failure Treatment

November 26, 2014 9:56 am | News | Comments

Cardio3 BioSciences announces the appointment of its three Co-Principal Investigators for...

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Italy's Ebola Patient Gets Experimental Treatment

November 26, 2014 9:21 am | News | Comments

An Italian doctor who contracted Ebola while working in Sierra Leone has arrived back in Italy and is being treated with the same experimental drugs. Read more...                 

Amgen, AstraZeneca Announce Positive Study Results for Plaque Psoriasis Drug

November 26, 2014 9:13 am | News | Comments

Amgen and AstraZeneca announced positive phase 3 study results for plaque psoriasis drug. Read more...                           

Valeant Receives FDA Approval for Acne Treatment

November 26, 2014 8:58 am | News | Comments

Valeant Pharmaceuticals announced it has received FDA approval of a gel that can treat acne vulgaris. Read more...                         

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Drugs to Block Angiogenesis Could Provide New TB Treatment

November 25, 2014 12:36 pm | News | Comments

The body responds to tuberculosis infection by locking the bacterial offenders into tiny clusters of immune cells called granulomas, which are a hallmark of the disease. This containment strategy succeeds at first, but eventually the bacteria manage to break out of these intercellular jails and spread throughout the body. Read more...

How Environment Contributes to Human Diseases

November 25, 2014 12:22 pm | News | Comments

Using a new imaging technique, National Institutes of Health researchers have found that the biological machinery that builds DNA can insert molecules into the DNA strand that are damaged as a result of environmental exposures. Read more...                

Protein Key to Development of Blood Stem Cells Identified

November 25, 2014 12:13 pm | by Peter Bracke, UCLA | News | Comments

Understanding the self-replication mechanisms is critical for improving stem cell therapies for blood-related diseases and cancers. Read more...                                           

$1B Alliance Between Menarini, Oxford BioTherapeutics for Enhanced AML Treatment

November 25, 2014 10:04 am | News | Comments

This is the first of five development programs between the two companies to enter the clinic in a $1 billion strategic oncology alliance. Read more...                   

Genetic Test Unlocks Cause of Brisbane Boy's Rare Disease

November 25, 2014 9:24 am | News | Comments

Queensland researchers have led an international effort to uncover the gene behind a young Brisbane boy’s rare developmental condition. Read more...                   

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Researchers Identify New Ways to Drain Cancer's 'Fuel Tank'

November 25, 2014 9:07 am | News | Comments

Scientists at the University of Manchester have discovered a potential weakness in cancer’s ability to return or become resistant to treatment. Read more...                  

Exciting Gains in Fighting Breast Cancer Hormone-Therapy Resistance

November 25, 2014 8:55 am | by Cynthia Fox, Science Editor | Articles | Comments

Guided by breakthrough research on the Estrogen Receptor 1 (ESR1) gene, many researchers and pharmaceutical companies are in hot pursuit of the next big anti-resistance breast cancer drug. Read more...                 

Improving The Odds of Beating Opioids

November 24, 2014 1:16 pm | by Sue McGreevy, Harvard University | News | Comments

Research indicates that live-in programs may result in higher levels of abstinence than the outpatient treatment that is currently the standard of care. Read more...                

New Drugs from Fish Oil Could Aid Artery Repair

November 24, 2014 12:33 pm | by Kathleen Masterson, University of California San Francisco | News | Comments

A common class of naturally occurring molecules from fish oil could help with artery repair. Read more...                         

Children's Relentless Seizures Halted By New Drug

November 24, 2014 12:22 pm | by Marla Paul, Northwestern University | News | Comments

An investigational medication has been found to effectively treat children with life-threatening and difficult-to-control epileptic seizures without side effects. Read more...              

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Pre-Empting Flu Evolution May Make Better Vaccines

November 21, 2014 9:37 am | News | Comments

An international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by ‘pre-empting’ the evolution of the influenza virus. Read more...           

Breakthrough Found to Help Manage Yellow Fever

November 21, 2014 9:24 am | News | Comments

Yellow fever is a disease that can result in symptoms ranging from fever to severe liver damage. Read more...                         

New Approach for Treating ALS

November 20, 2014 1:45 pm | News | Comments

Researchers show that the brain’s machinery for pumping out toxins is ratcheted up in ALS patients. Read more...                         

Global Obesity Costs Hits $2 Trillion

November 20, 2014 12:35 pm | by Danica Kirka - Associated Press | News | Comments

The global cost of obesity has risen to to nearly as much as smoking or the combined aspect of armed violence, war and terrorism. Read more...                    

Virus Discovery Could Impact HIV Drug Research

November 20, 2014 12:23 pm | News | Comments

A research team has unlocked the structure of an unusual virus that lives in volcanic hot springs. Read more...                         

Promising One-Two Punch for Lung Cancer

November 20, 2014 10:19 am | News | Comments

Scientists at the Salk Institute have discovered a powerful one-two punch for countering a common genetic mutation that often leads to drug-resistant cancers. The dual-drug therapy–with analogs already in use for other diseases–doubled the survival rate of mice with lung cancer and halted cancer in pancreatic cells. Read more...

Bacterial Infections Suppress Immune Response in Neurodermatitis

November 20, 2014 9:31 am | by Technische Universität München | News | Comments

The skin condition neurodermatitis affects nearly one in four children and also occurs frequently in adults. Many patients also develop infections in the dry, open patches of skin, for example due to colonization by the pathogenic bacterium Staphylococcus aureus, which is particularly abundant on the skin of neurodermatitis patients. Read more...

Chemical Disguise Transforms RNAi Drug Delivery

November 19, 2014 1:04 pm | News | Comments

Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery — it is extremely difficult to get RNAi drugs inside the cells in which they are needed.  Read more...

Light-Responding Blood Vessel Receptor May Be New Target

November 19, 2014 12:46 pm | by Johns Hopkins | News | Comments

A team of researchers from Johns Hopkins Medicine has discovered a receptor on blood vessels that causes the vessel to relax in response to light, making it potentially useful in treating vascular diseases. In addition, researchers discovered a previously unknown mechanism by which blood vessel function is regulated through light of a specific wavelength. Read more...

Maximizing the Power of Preclinical Cancer Research Tools

November 19, 2014 11:29 am | by Guizhong Liu, Senior Director of Cancer Biology, Crown Bioscience Inc. | Articles | Comments

Drug discovery is a protracted and uncertain process that needs to overcome many hurdles during preclinical and clinical development before it finally achieves regulatory approval for patient treatment. For every drug that reaches the marketplace, well over 100 have been abandoned at some point in their development. Read more...

New Laser Therapy Helps Slow Macular Degeneration

November 19, 2014 9:36 am | News | Comments

This new faster laser did not result in damage to the retina. Read more...                               

Sub-Standard Meds Flood Afghan Market

November 19, 2014 9:24 am | News | Comments

Up to 300 companies in Pakistan produce poor quality drugs exclusively for Afghanistan because their products do not meet Pakistani government standards. Read more...                

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