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The Lead

Why We Need Antibiotics

September 23, 2014 3:42 pm | Videos | Comments

Antibiotics revolutionized health care in the early 20th century, helping kill bacteria that once killed thousands of people. Read more...                                   

NIH Awards $35M for Centers for Collaborative Research in Fragile X

September 23, 2014 3:29 pm | News | Comments

NIH is awarding $35 million over the next five years to support the Centers for Collaborative...

Investigational Drug Could be Treatment for AML, Multiple Myeloma

September 23, 2014 1:57 pm | News | Comments

The investigational drug CX-5461 prolonged survival in mouse models of highly aggressive AML and...

New Approach Aims to Silence Cancer 'Survival Genes'

September 23, 2014 11:20 am | News | Comments

Scientists are working on a promising new...

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WHO: 21,000 Ebola Cases by November if No Changes

September 23, 2014 10:33 am | by Maria Cheng, AP Medical Writer | News | Comments

New estimates from the WHO warn the number of Ebola cases could hit 21,000 in six weeks unless efforts to curb the outbreak are ramped up, according to an analysis published by the New England Journal of Medicine. Read more...       

New Chip Promising for Tumor-Targeting Research

September 22, 2014 3:59 pm | News | Comments

Researchers have developed a chip capable of simulating a tumor's "microenvironment" and plan to use the new system to test the effectiveness of nanoparticles and drugs that target cancer. Read more...              

Battling Superbugs

September 22, 2014 3:57 pm | News | Comments

Engineers have turned a powerful new weapon on superbugs. Using a gene-editing system that can disable any target gene, they have shown that they can selectively kill bacteria carrying harmful genes that confer antibiotic resistance or cause disease. Read more...

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Tekmira’s Ebola Drug Gets Regulatory Framework

September 22, 2014 2:56 pm | News | Comments

Tekmira Pharmaceuticals Corp. announced that the FDA has authorized Tekmira to provide TKM-Ebola for treatment under expanded access protocols to subjects with confirmed or suspected Ebola virus infections. Read more...          

Researchers Describe New Cancer Drug Target Involving Lipid Chemical Messengers

September 22, 2014 10:11 am | News | Comments

More than half of human cancers have abnormally upregulated chemical signals related to lipid metabolism, yet how these signals are controlled during tumor formation is not fully understood. Researchers are reporting that TIPE3, a newly described oncogenic protein, promotes cancer by targeting these pathways. Read more...

'Evolved' Protein Created to Stop Cancer from Spreading

September 22, 2014 9:25 am | News | Comments

A team of researchers has developed a protein therapy that disrupts the process that causes cancer cells to break away from original tumor sites, travel through the bloodstream and start aggressive new growths elsewhere in the body. Read more... 

Modified Antibiotic Can Vanquish Resistant Bacteria

September 19, 2014 10:23 am | News | Comments

Scientists have devised a new antibiotic based on vancomycin that is powerfully effective against vancomycin-resistant strains of MRSA and other disease-causing bacteria. Read more...                   

A New Way to Prevent the Spread of Devastating Diseases

September 19, 2014 10:18 am | News | Comments

For decades, researchers have tried to develop broadly effective vaccines to prevent the spread of illnesses such as HIV, malaria, and tuberculosis. While limited progress has been made along these lines, there are still no licensed vaccinations available that can protect against these diseases. Now, researchers are approaching the problem in a different way. Read more...

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New Approach to Arthritis Drug Delivery Could Help Avoid Side Effects

September 19, 2014 9:54 am | News | Comments

A new approach to arthritis treatment, which avoids unforeseen side effects by delivering drugs exclusively to affected inflamed joints, has been developed by researchers in London. Read more...                

Afamelanotide Holds Promise as Vitiligo Treatment

September 19, 2014 8:30 am | Videos | Comments

A treatment regimen is safe and effective for restoring skin pigmentation in vitiligo patients, according to a new study. Read more...                                 

Why Live Vaccines May be Most Effective for Preventing Salmonella Infection

September 18, 2014 11:20 pm | News | Comments

Vaccines against Salmonella that use a live, but weakened, form of the bacteria are more effective than those that use only dead fragments because of the particular way in which they stimulate the immune system, according to new research. Read more...

White House Orders Plan for Antibiotic Resistance

September 18, 2014 10:57 pm | News | Comments

Signaling the seriousness of the threat posed by antibiotic-resistant germs, President Barack Obama on Thursday ordered the government to create a national plan to fight them by early 2015. Read more...             

Cancer Progress Report: Research is Transforming Lives

September 17, 2014 3:10 pm | News | Comments

Research continues to fuel significant advances against cancer. This progress has been spurred by federal investments in the NIH and National Cancer Institute, according to the American Association for Cancer Research's fourth annual Cancer Progress Report. Read more...

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Australia Promises $6.4M to Fight Ebola

September 17, 2014 10:17 am | News | Comments

Australia announced on Wednesday it will immediately provide an additional 7 million Australian dollars ($6.4 million) to help the international response to the Ebola outbreak in West Africa. Read more...              

UN: Nearly $1B Needed Now to Stop Ebola

September 16, 2014 9:45 am | by John Heilprin and Krista Larson | News | Comments

The World Health Organization is warning that the number of Ebola cases in West Africa could double every three weeks. The estimate comes Tuesday as the U.N. health agency said the cost of containing the deadly virus has risen to nearly $1 billion. Read more...

NIH Awards Aim to Improve Understanding of Cell Pathways

September 15, 2014 10:33 am | News | Comments

Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses. Discovering such cell responses will improve scientists’ understanding of cell pathways and aid in the development of new therapies. Read more...

Researchers Find Defense Mechanism Against Viruses

September 12, 2014 2:00 pm | News | Comments

Researchers have discovered that a known quality control mechanism in human, animal and plant cells is active against viruses. They think it might represent one of the oldest defense mechanisms against viruses in evolutionary history.

Using Antibiotics to Negate Heart Side Effects

September 12, 2014 7:00 am | News | Comments

A research team from the University of Bristol is looking at whether an antibiotic has the potential to prevent or treat irregular heartbeats brought on by other medicines. A research team will study whether low levels of the antibiotic erythromycin can block negative side effects, and will further investigate the mechanisms involved.

Our Microbes Are a Rich Source of Drugs

September 11, 2014 3:08 pm | News | Comments

Bacteria that normally live in and upon us have genetic blueprints that enable them to make thousands of molecules that act like drugs, and some of these molecules might serve as the basis for new human therapeutics, according to a new study. Read more...

Compound Protects Brain Cells After TBI

September 11, 2014 3:03 pm | News | Comments

A new class of compounds has now been shown to protect brain cells from the type of damage caused by blast-mediated traumatic brain injury (TBI). Read more...                           

7 U.S.-Based Researchers Share $1.3M Eyesight Prize

September 11, 2014 10:37 am | News | Comments

Seven U.S.-based researchers are sharing a prize of 1 million euro ($1.3 million) from a Portuguese foundation for their work developing treatment for angiogenic diseases of the retina, the leading cause of blindness in the developed world. Read more...

Gates Foundation to Spend $50M on Ebola Response

September 11, 2014 8:30 am | by Donna Gordon Blankinship | News | Comments

The Bill & Melinda Gates Foundation announced that it will spend $50 million- on top of $10 million already committed- to support emergency response to the Ebola outbreak in West Africa. Read more...             

Blocking One Receptor on Cells Could Halt RA

September 10, 2014 2:00 pm | News | Comments

Researchers have shown for the first time how the activation of a receptor provokes the inflammation and bone degradation of rheumatoid arthritis. Read more...                          

Nutrient Combo May be 'Super Pill' to Treat Depression

September 10, 2014 10:41 am | News | Comments

A new study will help people suffering from clinical depression by offering them new combination of nutrient-based medications to enhance mood. Read more...                           

Sleep, Anxiety Meds May Increase Alzheimer's Risk

September 10, 2014 10:23 am | News | Comments

Taking benzodiazepines (widely prescribed drugs to treat anxiety and insomnia) is associated with an increased risk of developing Alzheimer's disease, particularly for long-term users, suggests a new study. Read more...         

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