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Researchers Demonstrate Advances in Creating Blood Cancer Treatment

October 21, 2014 2:33 pm | News | Comments

Researchers at NYU Langone Medical Center and elsewhere said that blocking the action of an enzyme “switch” needed to activate tumor growth is emerging as a practical strategy for treating T-cell acute lymphoblastic leukemia. Read more...    

Once CD8 T Cells Take on One Virus, They'll Fight Others Too

October 21, 2014 2:02 pm | News | Comments

Scientists think of CD8 T cells as long-lived...

Supercomputers Link Proteins to Drug Side Effects

October 21, 2014 1:46 pm | News | Comments

Lawrence Livermore National Laboratory...

Embryonic Stem Cells in Trial for Diabetes

October 20, 2014 4:08 pm | by Cynthia Fox, Science Editor | Articles | Comments

As San Diego’s ViaCyte was in the midst of...

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Lab-Developed Intestinal Organoids Form Mature Human Tissue in Mice

October 20, 2014 2:19 pm | News | Comments

Researchers have successfully transplanted “organoids” of functioning human intestinal tissue grown from pluripotent stem cells in a lab dish into mice – creating an unprecedented model for studying diseases of the intestine. Read more...

New Front in War on Alzheimer’s, Other Protein-Folding Diseases

October 17, 2014 10:12 am | News | Comments

A surprise discovery that overturns decades of thinking about how the body fixes proteins that come unraveled greatly expands opportunities for therapies to prevent diseases such as Alzheimer’s and Parkinson’s, which have been linked to the accumulation of improperly folded proteins in the brain. Read more...

Scientists Develop Decoy Drug to Form New Connections

October 16, 2014 12:18 pm | News | Comments

A team of Stanford Bio-X scientists has restored the ability of adult mice to form new connections in the brain. If the finding works in people, it has the potential to help adults recover from stroke and forms of blindness or to prevent the loss of connections in Alzheimer's disease. Read more...

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Study Finds Neurons "Fine Tune" At Genetic Level

October 15, 2014 1:16 pm | News | Comments

Neurons are electrically charged cells in the nervous system that interpret and transmit information using electrical and chemical signals. A neuron’s electrical charge is determined by the flow of ions – charged atoms – in and out of the cell through pores, called ion channels. Read more...

DNA-based ‘Nano-Cocoons’ Attack, Kill Cancer Cells

October 15, 2014 12:55 pm | News | Comments

Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale “cocoons” made of DNA that target cancer cells and trick the cells into absorbing the cocoon before unleashing anticancer drugs. Read more...

Reversing Idiopathic Pulmonary Fibrosis

October 15, 2014 10:14 am | by Cynthia Fox, Science Editor | News | Comments

Lethal fibrosis in lungs of idiopathic pulmonary fibrosis (IPF) mouse models can be reversed, say Yale University researchers. Read more...                                      

Combating Bladder Cancer With Approved Drug

October 14, 2014 1:53 pm | News | Comments

A drug that activates targets of the hedgehog signaling pathway, which is lost when bladder cancer invades, could prevent the progression of the disease in humans. Clinical trials are planned. Read more...                  

Researchers Treat Pulmonary Hypertension Through the Leaves of Plants

October 14, 2014 10:18 am | News | Comments

Researchers at the University of Pennsylvania and the University of Florida have identified a drug that can be used to treat pulmonary hypertension, a disease for which few therapy options exist. Read more...                            

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Targeted Payload Therapies Using RIT Hit the Right Marks

October 13, 2014 4:50 pm | by Dragan Cicic, M.D., MBA, Chief Operating Officer and Chief Medical Officer, Actinium Pharmaceuticals | Articles | Comments

For patients with acute myeloid leukemia (AML), there is both good news and bad news – the good news is that standard induction therapy, using cytarabine and an anthracycline, produces complete responses in half to almost three-quarters of cases. The bad news? Read more...

New Cancer Drug to Begin Trials in Multiple Myeloma Patients

October 13, 2014 3:11 pm | News | Comments

Scientists at Imperial College London have developed a new cancer drug which they plan to trial in multiple myeloma patients by the end of next year. Read more...                            

Greater Rates of Mitochondrial Mutations in Children Born to Older Mothers

October 13, 2014 2:54 pm | News | Comments

The discovery of a "maternal age effect" by a team of Penn State scientists that could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells -- and the transmission of these mutations to children -- could provide valuable insights for genetic counseling. Read more... 

Giant Step Toward New Diabetes Treatment

October 10, 2014 9:55 am | News | Comments

Harvard stem cell researchers announced that they have made a giant leap forward in the quest to find a truly effective treatment for type 1 diabetes, a condition that affects an estimated 3 million Americans at a cost of about $15 billion annually Read more...

Cancer Drug Destroys Tumors in Pre-Clinical Trials

October 9, 2014 3:18 pm | News | Comments

Scientists at QIMR Berghofer Medical Research Institute have used an experimental drug produced from the seeds of a rainforest plant to cure solid cancer tumors in preclinical trials. Read more...                     

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Researchers Find that Drug Used for Another Disease Slows Parkinson’s Progression

October 9, 2014 10:24 am | News | Comments

A new study from University of California, Los Angeles (UCLA) found that a drug being evaluated to treat an entirely different disorder helped slow the progression of Parkinson’s disease in mice. Read more...

'Unsung' Cells Double the Benefits of a New Osteoporosis Drug

October 8, 2014 10:48 am | News | Comments

Experiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder, according to Johns Hopkins researchers. Read more...

Green Tea-based ‘Missiles’ May Kill Cancer Cells

October 7, 2014 3:31 pm | News | Comments

Green tea has long been known for its anti-oxidant, anti-cancer, anti-aging and anti-microbial properties. A group of researchers from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR has taken the health benefits of green tea to the next level by using one of its ingredients to develop a drug delivery system, which kills cancer cells more efficiently. Read more...

A New Pathway Discovered Regulating Autoimmune Diseases

October 7, 2014 2:32 pm | News | Comments

The main function of the immune system is to protect against diseases and infections. For unknown reasons our immune system attacks healthy cells, tissues and organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis. There are currently no existing cures for these diseases. Read more...

Ancient Protein-Making Enzyme Moonlights as DNA Protector

October 3, 2014 10:54 am | News | Comments

Scientists at TSRI have found that an enzyme best known for its fundamental role in building proteins has a second major function: to protect DNA during times of cellular stress. Read more...

Osteoporosis Treatment May also Benefit Breast Cancer Patients

October 3, 2014 10:39 am | News | Comments

Treatment approaches to reduce the risk of metastasis associated with breast cancer may be one step closer to becoming a reality. According to a study led by a team at the Research Institute of the MUCH, findings show that medication used to treat bone deterioration in post-menopausal women may also slow skeletal metastasis caused from breast cancer. Read more...

‘Stealth’ Nanoparticles Could Improve Cancer Vaccines

October 1, 2014 4:05 pm | News | Comments

Cancer vaccines have recently emerged as a promising approach for killing tumor cells before they spread. But so far, most clinical candidates haven’t worked that well. Now, scientists have developed a new way to deliver vaccines that successfully stifled tumor growth when tested in laboratory mice. Read more...

Early Antibiotic Use Linked to Childhood Obesity Risk

September 30, 2014 3:16 pm | News | Comments

The use of broad-spectrum antibiotics by children before the age of 24 months was associated with increased risk of obesity in early childhood. Read more...                         

Scientists Engineer Antibiotics in Race Against Drug Resistance

September 30, 2014 2:56 pm | News | Comments

We face an urgent global health problem because scientists are not developing new antibiotics as fast as bacteria are developing antibiotic resistance. But new research from UCLA has made important progress toward solving this problem. Read more...

Testing Cancer Drugs' Benefit for Individual Patients

September 30, 2014 2:28 pm | News | Comments

An official at a life sciences startup based on a Purdue University innovation says his company may help oncologists see faster than ever which drug therapies will benefit cancer patients and to what extent. Read more...         

Ebola Labs, Parts for Clinic Arrive in Liberia

September 30, 2014 10:15 am | by Jonathan Paye-Layleh | News | Comments

U.S. mobile Ebola labs should be up and running in Liberia this week, and American troops have broken ground for a field hospital, as the international community races to increase the ability to care for the spiraling number of people infected with the dreaded disease. Read more...

Researchers Engineer New Mouse Model to Study Disease

September 26, 2014 3:33 pm | News | Comments

Researchers from the Broad Institute and MIT have created a new mouse model to simplify application of the CRISPR-Cas9 system for genome-editing experiments in living animals. Read more...

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