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Cannabis Science to Test Multiple Strains for Clinical Development

July 31, 2014 1:36 pm | News | Comments

Cannabis Science Inc. announced that it has commenced production of multiple strains of cannabis and European Union certified hemp varieties to initiate scientific research to select the best strains for development of clinical drugs. Read more... 

Drug Target Identified for Common Childhood Blood Cancer

July 31, 2014 1:13 pm | News | Comments

In what is believed to be the largest genetic analysis of what triggers and propels progression...

New Mouse Model May Open Autism Treatment Avenues

July 31, 2014 9:23 am | News | Comments

Following a hunch about a brain receptor, researchers have developed a new mouse model that may...

SRI Snags NIH Contract for HIV, AIDS Therapies

July 25, 2014 2:47 pm | News | Comments

SRI International has been awarded a new $49 million, seven-year contract with the NIAID, part...

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EPFL, Nearmedic Pharma Partner to Fight Tuberculosis

July 25, 2014 2:42 pm | News | Comments

The pharmaceutical company Nearmedic is collaborating with EPFL to participate in the development of a treatment against tuberculosis. Read more...                             

Research Shows that One CF Drug Counteracts Another

July 24, 2014 11:08 am | News | Comments

In lab experiments using tissue samples cultured from cystic fibrosis patients, scientists at the UNC School of Medicine and the UNC Marsico Lung Institute have shown that a new CF drug counteracts the intended beneficial molecular effect of another CF drug. Read more...

MedImmune, Advaxis Partner on Immuno-Oncology Combo Trial

July 22, 2014 10:59 am | News | Comments

AstraZeneca announced that MedImmune, its global biologics research and development arm, has entered into a clinical trial collaboration with Advaxis Inc., a US-based biotechnology company developing cancer immunotherapies, providing further evidence of MedImmune’s commitment to explore novel combination approaches. Read more...

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NIH Grants Sorrento Funding for Development of Small Molecule Inhibitor

July 21, 2014 3:57 pm | News | Comments

Sorrento Therapeutics Inc. announced that it has received non-dilutive funding for the preclinical development of a small molecule inhibitor targeting the important oncogenic transcription factor Myc. Read more…           

Protein Injection Halts Diabetes in Mice

July 17, 2014 1:36 pm | Videos | Comments

In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days. The discovery could lead to a new generation of diabetes drugs. Read more...

Cannabis Compound Could Slow Tumor Growth, Research Shows

July 14, 2014 2:26 pm | News | Comments

Scientists have shown how the main psychoactive ingredient in cannabis could reduce tumor growth in cancer patients. Read more...                                   

Combo Therapy More Effective in Removing Beta-Amyloid from Mice Brains

July 14, 2014 2:19 pm | News | Comments

Eli Lilly and Co. announced results from its non-clinical study in genetically engineered mice examining combination therapy with the murine version of the beta-amyloid antibody N3pG and beta-secretase inhibitor BACE. Read more...      

New Compound Treats Blindness, Diabetes in Mice

July 11, 2014 3:03 pm | News | Comments

In a new study, a chemical compound designed to precisely target part of a crucial cellular quality-control network provided significant protection, in rats and mice, against degenerative forms of blindness and diabetes. Read more...      

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DelMar Receives Canadian Funding

July 9, 2014 3:09 pm | News | Comments

DelMar Pharmaceuticals Inc. announced that the company has been awarded a non-refundable financial contribution of up to CDN$194,000 from the National Research Council of Canada's Industrial Research Assistance Program (NRC-IRAP) to support personnel and research costs. Read more...

Domainex Reports Success of COPD Drug

July 9, 2014 2:57 pm | News | Comments

Domainex Ltd, a UK-based drug discovery company developing first-in-class small-molecule inhibitors of two closely-related pro-inflammatory kinases TBK1 and IKK-epsilon announced that its lead compound has demonstrated a more potent effect in a key model of COPD than either roflumulast or a p38 inhibitor. Read more...

HIV Vaccine Research Team Loses $1.38M Grant

July 9, 2014 12:54 pm | by David Pitt | News | Comments

An AIDS research team at Iowa State University will not get the final $1.38 million payment of a National Institutes of Health five-year grant after a team member admitted last year to faking research results. Read more...        

Researcher Charged in HIV Vaccine Fraud Case

June 25, 2014 1:19 pm | by Ryan J. Foley, Associated Press | News | Comments

Responding to a major case of research misconduct, federal prosecutors have taken the rare step of filing charges against a scientist after he admitted falsifying data that led to millions in grants and hopes of a breakthrough in AIDS vaccine research. Read more...

Apitope Starts Preclinical Studies of Graves' Disease Drug

June 19, 2014 3:00 pm | News | Comments

Apitope, the drug discovery and development company focused on disease-modifying treatments for patients with autoimmune and allergic diseases, announced that it has started preclinical development of its novel peptide therapy ATX-GD-459 for the treatment of Graves' disease. Read more...

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Lixte's Lead Drug Enhances Chemotherapy Effectiveness

June 18, 2014 5:48 pm | News | Comments

The journal Molecular Cancer Therapeutics has published an article on Lixte's lead compound LB-100 entitled "Inhibition of protein phosphatase 2A enhances cytotoxicity and accessibility of chemotherapeutic drugs to hepatocellular carcinomas." Read more...

In Vitro Cell Models for Cortical Neurophysiology

June 16, 2014 2:38 pm | Product Releases | Comments

AMSBIO offers an extensive range of iPSC derived neural cells including normal and Alzheimer's disease neural progenitor cells, and cerebral cortical neurons. Read more...

Mouse Models Mimic Human Breast Cancer

June 5, 2014 2:16 pm | News | Comments

Scientists have routinely used mice to replicate aspects of human breast cancer in an effort to find a cure to the most common type of cancer among women. But how effective are these preclinical models in actually mimicking the disease and giving scientists the ability to develop real comparisons? Read more...

Nanodaisies Deliver Drug Cocktail to Cancer Cells

May 28, 2014 1:53 pm | News | Comments

Biomedical engineering researchers at North Carolina State University and the University of North Carolina at Chapel Hill have developed daisy-shaped, nanoscale structures that are made predominantly of anti-cancer drugs and are capable of introducing a “cocktail” of multiple drugs into cancer cells. Read more...

Scientists ID New Drug Targets for Triple Negative Breast Cancer

May 27, 2014 2:13 pm | News | Comments

The suppression of two genes reduce breast cancer tumor formation and metastasis by interfering with blood vessel formation and recruitment, report scientists from Houston Methodist and five other institutions in the Proceedings of the National Academy of Sciences. Read more...

Pain Killers Improve Metabolic Health and Longevity

May 23, 2014 11:26 am | by Robert Sanders, Media Relations, UC Berkeley | News | Comments

Blocking a pain receptor in mice not only extends their lifespan, suggesting that pain might drive the aging process, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar. Read more...

DSI Launches First-Ever Glucose Telemetry Implant

May 21, 2014 1:38 pm | News | Comments

Data Sciences International, the global leader in wireless physiologic monitoring, has introduced the first-ever glucose telemetry implant for obtaining continuous, real-time measurements of blood glucose in laboratory animals. Read more...

Compound Reverses Alzheimer’s Symptoms in Mice

May 21, 2014 10:57 am | News | Comments

A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to new findings. Read more...               

Researchers Find Key Factor in Early Auditory Development

May 20, 2014 2:48 pm | News | Comments

Researchers at the National Institute on Deafness and Other Communication Disorders of the National Institutes of Health have uncovered a molecule, known as Bmp7, in an animal model that acts as a key player in establishing the organization of the auditory system. Read more...

Researchers Find Key to HIV Comorbidities

May 19, 2014 1:50 pm | News | Comments

The first direct proof of a long-suspected cause of multiple HIV-related health complications was recently obtained by a team led by the University of Pittsburgh Center for Vaccine Research (CVR), supporting complementary therapies to antiretroviral drugs to significantly slow HIV progression. Read more...

Painkillers May Decrease Susceptibility to Recurring Urinary Infections

May 19, 2014 10:57 am | News | Comments

Women plagued by repeated urinary tract infections may be able to prevent the infections with help from over-the-counter painkillers, new research in mice shows. Read more...                     

Anti-Depressant Reduces Alzheimer’s Plaque Growth by 78%

May 15, 2014 1:32 pm | by Cynthia Fox, Science Editor | Articles | Comments

A common antidepressant - the selective serotonin reuptake inhibitor (SSRI) citalopram - can dramatically halt growth of Alzheimer’s plaque, report a team from Missouri and Pennsylvania Wednesday in Science Translational Medicine. Read more...

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