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Mouse Model Could Accelerate Ebola Treatment Research

October 31, 2014 1:36 pm | News | Comments

Researchers at the University of North Carolina at Chapel Hill and colleagues have developed the first genetic strain of mice that can be infected with Ebola and display symptoms similar to those that humans experience. Read more...     

Making Lab-Grown Tissues Stronger

October 30, 2014 1:30 pm | News | Comments

Lab-grown tissues...

‘Treasure in Saliva’ May Reveal Diseases Early Enough to Treat

October 30, 2014 12:34 pm | News | Comments

UCLA research could...

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Body Clock Gene May Impact Drug Delivery

October 30, 2014 10:32 am | News | Comments

A new effort mapping 24-hour patterns of expression for thousands of genes in 12 different mouse organs provides important clues about how the role of timing may influence the way drugs work in the body. Read more...        

Research Reveals Fish Are Smarter Than We Thought

October 30, 2014 10:08 am | News | Comments

The discovery could pave the way for new medical advances in stroke rehabilitation and in treatments for attention deficit disorders. Read more...                        

Scientists Uncover Major Factor in Development of Huntington's

October 29, 2014 12:16 pm | News | Comments

Scientists from The Scripps Research Institute have uncovered a major contributor to Huntington’s disease. Read more...                        

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Blood Test May Diagnose Early Onset Alzheimer's

October 29, 2014 9:52 am | News | Comments

A non-invasive blood test that could diagnose early onset Alzheimer’s disease with increased accuracy. Read more...                        

BDSI Developing Long-Acting Vaccine for Pain Treatment

October 28, 2014 1:21 pm | News | Comments

BioDelivery Sciences International is developing a long-acting injectable for use in pain treatments. Read more...                        

Better Chemo Possible Through Targeted Delivery

October 28, 2014 12:38 pm | News | Comments

A new study from MIT, Brigham and Women’s Hospital, and Johns Hopkins University suggests that delivering chemotherapy directly into the brain cavity may offer a better way to treat tumors that have metastasized to the brain. Read more...    

Swiss Agency Approves Trial for Ebola Vaccine

October 28, 2014 9:56 am | News | Comments

The Swiss agency that regulates new drugs said Tuesday it has approved an application for a clinical trial with an experimental Ebola vaccine. Read more...                 

Drug Combination Shows Promise As Powerful Breast Cancer Treatment

October 28, 2014 9:23 am | News | Comments

Doctors discovered a potent drug combination that shows promise as a powerful treatment for breast cancer. Read more...                        

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Monitoring Lipid, Detergent Content in Biological Samples Using IR-Based Spectrometry

October 27, 2014 4:01 pm | by Chandreyee Das, Ph.D., Senior Technical Writer, Protein Detection, EMD Millipore | Articles | Comments

Many biological samples in the course of drug development research are rich in lipid content, such as adipose tissue homogenates, brain and liver tissue extracts, lipemic samples and breast milk. Read more...

Merck Announces New Breakthrough Therapy Designation for Lung Cancer

October 27, 2014 1:37 pm | News | Comments

Merck announced that the FDA granted Breakthrough Therapy Designation for the treatment of lung cancer. Read more...                        

Researcher Adapting New Technologies for Fighting Worm Infections

October 27, 2014 1:08 pm | News | Comments

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. Read more...                       

Heart Drug May Help Treat ALS, Mouse Study Shows

October 27, 2014 11:46 am | by Michael C. Purdy | News | Comments

Digoxin, a medication used in the treatment of heart failure, may be adaptable for the treatment of ALS, suggests new research at Washington University School of Medicine in St. Louis. Read more...          

Researchers Find New Target for Treating Childhood Cancers

October 24, 2014 10:31 am | News | Comments

Scientists at the University of Liverpool have uncovered a new target for drugs that could battle a lethal childhood cancer known as neuroblastoma. Read more...                 

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New Technique Achieved With Profound Implications for Drug Development

October 24, 2014 9:29 am | News | Comments

A team from The Scripps Research Institute has established a new C-H activation technique that opens the door to creating a broader range of pure molecules of one-handedness or “chirality” by eliminating previous starting-material limitations. Read more...

Experimental Breast Cancer Drug Has Promise in Combination Therapy

October 23, 2014 1:40 pm | News | Comments

Ewing sarcoma tumors disappeared and did not return in more than 70 percent of mice treated with combination therapy that included drugs from a family of experimental agents developed to fight breast cancer, reported St. Jude Children's Research Hospital scientists.  Read more...

New Genome Analysis Finds Markers of Aggresive Tumors

October 23, 2014 1:21 pm | News | Comments

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients. Read more...    

Real-Time Tracking System Developed to Watch Dangerous Bacteria

October 23, 2014 1:02 pm | News | Comments

Combining a PET scanner with a new chemical tracer that selectively tags specific types of bacteria, Johns Hopkins researchers working with mice report they have devised a way to detect and monitor in real time infections. Read more...    

New Anti-Cancer Drug Shows Few Side-Effects in Mice

October 23, 2014 10:15 am | News | Comments

A new drug, known as OTS964, can eradicate aggressive human lung cancers transplanted into mice, according to a new report. Read more...                     

Microscopic “Walkers” Find Way Across Cell Surfaces

October 23, 2014 9:47 am | News | Comments

Technology could provide a way to deliver probes or drugs to cell structures without outside guidance. Read more...                                         

UNC Researchers Found New Characters In Cancer Cells

October 22, 2014 1:47 pm | News | Comments

UNC School of Medicine researchers have pinpointed a set of intriguing characteristics in a previously unknown subpopulation of melanoma cancer cells in blood vessels of tumors. Read more...            

Researchers Demonstrate Advances in Creating Blood Cancer Treatment

October 21, 2014 2:33 pm | News | Comments

Researchers at NYU Langone Medical Center and elsewhere said that blocking the action of an enzyme “switch” needed to activate tumor growth is emerging as a practical strategy for treating T-cell acute lymphoblastic leukemia. Read more...    

Once CD8 T Cells Take on One Virus, They'll Fight Others Too

October 21, 2014 2:02 pm | News | Comments

Scientists think of CD8 T cells as long-lived cells that become tuned to fight just one pathogen, but a study finds that once CD8 T cells fight one pathogen, they also join the body's "innate" immune system, ready to answer the calls of the cytokine signals that are set off by a wide variety of infections. Read more...

Supercomputers Link Proteins to Drug Side Effects

October 21, 2014 1:46 pm | News | Comments

Lawrence Livermore National Laboratory researchers have discovered a high-tech method of using supercomputers to identify proteins that cause medications to have certain adverse drug reactions (ADR) or side effects. Read more...         

Embryonic Stem Cells in Trial for Diabetes

October 20, 2014 4:08 pm | by Cynthia Fox, Science Editor | Articles | Comments

As San Diego’s ViaCyte was in the midst of launching the first FDA-approved embryonic stem (ES) cell clinical trial for diabetes last week, Boston’s Harvard University reported that beta cells from ES cells “cured” diabetic mouse-models. Read more...

Lab-Developed Intestinal Organoids Form Mature Human Tissue in Mice

October 20, 2014 2:19 pm | News | Comments

Researchers have successfully transplanted “organoids” of functioning human intestinal tissue grown from pluripotent stem cells in a lab dish into mice – creating an unprecedented model for studying diseases of the intestine. Read more...

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