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The Lead

Vitamin D Levels Help Predict Survival of Sick Cats

May 15, 2015 12:48 pm | by Bevin Fletcher, Associate Editor | News | Comments

Vitamin D could give your sickly feline friend its 10th life, according to a recent study. New research from the University of Edinburgh found that higher levels of vitamin D were linked to increased survival changes for hospitalized cats. Read more...

Early Obesity Research Finds Leptin Hormone May Not Be Overeating Culprit

May 15, 2015 12:42 pm | by University of Cincinnati | News | Comments

For years, scientists have pointed to leptin resistance as a possible cause of obesity. Research...

PharmaMar Announces New Oncology Advances with Yondelis, PM1183 Compounds

May 15, 2015 9:18 am | News | Comments

The studies were selected for oral discussion session and poster presentation at the American...

Findings Should Enhance Treatments for Stopping Immune System Attacks

May 15, 2015 9:12 am | by University of Manchester | News | Comments

Scientists have made an important discovery about an immune cell which is already being used in...

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Daily news and top headlines for drug research professionals

Disrupting Cancer Pathway Could Enhance New Immunotherapies

May 11, 2015 11:26 am | by University of Chicago Medical Center | News | Comments

Understanding how to overrule a signaling pathway that can cause treatments to fail in metastatic melanoma patients should help physicians extend the benefits of recently approved immunity-boosting drugs known as checkpoint inhibitors to more patients. Read more..

Statin Drugs Can Delay Prostate Cancer Progression in Patients, Study Shows

May 7, 2015 11:25 am | by Dana-Farber Cancer Institute | News | Comments

​Men who went on cholesterol-lowering statin drugs when they began androgen deprivation therapy for prostate cancer had a longer time in which their disease was under control than did men who didn't take statins, a clinical trial led by Dana-Farber Cancer Institute investigators shows. Read more...

One Step Closer to an Insulin Vaccine for Type 1 Diabetes

May 5, 2015 3:50 pm | by University of Bristol | News | Comments

An international team of researchers from Bristol, Dresden, Munich, Vienna and Denver have successfully completed the first step in the development of an insulin vaccine to prevent type 1 diabetes. Read more...

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Diabetes Glucose and Alzheimer’s Brain Plaques Could be Connected

May 5, 2015 12:05 pm | by Seth Augenstein, Digital Reporter | News | Comments

Diabetes and Alzheimer’s could have a cause-and-effect connection, according to a study published this week. Elevated glucose in the blood caused increased levels of amyloid beta, a fundamental ingredient of brain plaques in Alzheimer’s brains, in mice analyzed by the team from the Washington University School of Medicine in St. Louis. Read more...

UniQuest, AstraZeneca Collaborate on Drug Discovery

May 5, 2015 8:31 am | by University of Queensland | News | Comments

AstraZeneca and UniQuest have formed an open innovation program to support academic research that holds promise of new therapeutic drugs. Read more...

Foreign Antibodies Mobilize Immune System to Fight Cancer, Researchers Find

May 4, 2015 11:48 am | by Stanford University | News | Comments

A mouse’s T cells can be primed to attack and eliminate a malignant tumor by injecting antibodies from another mouse with resistance to the tumor, as well as by activating certain signaling cells, a study has found. Read more...

Prostate Cancer Combination Treatment Could Beat Disease at Its Own Game: Early Study

April 30, 2015 10:23 am | by Seth Augenstein, Digital Reporter | News | Comments

Through chemoimmunotherapy, a chemical one-two punch, a team of doctors said they are now having new success in mouse models. Read more...

Fragile X Syndrome: Building a Case for an Alternative Treatment Strategy

April 24, 2015 12:01 pm | by Emory Health Sciences | News | Comments

New research strengthens a potential strategy for treating fragile X syndrome, the most common inherited form of intellectual disability. Read more...

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Finding Points to a Cause of Chronic Lung Disease

April 23, 2015 1:58 pm | by Washington University in St. Louis | News | Comments

Scientists have long suspected that respiratory viruses — the sort that cause common colds or bronchitis — play a critical role in the long-term development of chronic lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). Read more...

Harnessing the Clinical Potential of Microvesicles Released from Cancer Cells

April 22, 2015 12:14 pm | by William G. Gilroy, University of Notre Dame | News | Comments

Over the past few years, extracellular vesicles, or membrane sacs secreted from cells, have emerged as important mediators by which cells communicate with their surroundings to regulate a diverse range of biological processes. Read more..

A New Lease on Life for Prostate Tissue

April 21, 2015 11:19 am | by Rutgers University | News | Comments

What if a prostate cancer patient could learn which anti-cancer treatments would work best for him without having to swallow a single pill or endure a single intravenous line or injection? Read more...

Cancer Drug Shows Promise for Treating Hepatitis B

April 20, 2015 4:46 pm | by Walter + Eliza Hall Research Institute | News | Comments

​Australian scientists have found a potential cure for hepatitis B virus (HBV) infections. Read more...

Childhood Syndrome Combining Lung Disease, Arthritis Identified

April 20, 2015 11:07 am | by UCSF | News | Comments

Discovery suggests mechanism, possible therapies for severe disorder. Read more...

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Electronic Micropump Could Deliver Treatment to Specific Brain Region

April 17, 2015 10:13 am | by Stephanie Guzowski, Editor | News | Comments

There is an exactness that must be taken into account when treating neurological disorders. In treating epilepsy, for example, a condition in which nerve cell activity in the brain is disturbed, causing seizures, a drug needs to be delivered directly to a specific brain region—but without negatively affecting healthy brain regions. Read more...

How Molecule Protects Brain Cells in Parkinson’s Disease Model

April 15, 2015 11:35 am | by Scripps Research Institute | News | Comments

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found how a widely known but little-studied enzyme protects brain cells in models of Parkinson’s disease. Read more...

Recruiting the Entire Immune System to Attack Cancer

April 14, 2015 10:48 am | by MIT News | News | Comments

The human immune system is poised to spring into action at the first sign of a foreign invader, but it often fails to eliminate tumors that arise from the body’s own cells. Cancer biologists hope to harness that untapped power using an approach known as cancer immunotherapy. Read more..

Tau is the Main Culprit in Alzheimer’s, say Two Studies

April 7, 2015 5:17 pm | by Cynthia Fox, Science Editor | Articles | Comments

Two recent studies have concluded that tau, not amyloid, is the main driver behind Alzheimer’s disease (AD). Read more...

Experimental Cancer Drug Restores Memory in Mouse Model of Alzheimer’s

April 1, 2015 12:37 pm | by Yale University | News | Comments

Memory and as well as connections between brain cells were restored in mice with a model of Alzheimer’s given an experimental cancer drug, Yale School of Medicine researchers reported in the journal Annals of Neurology. Read more...

Medieval Remedy Found to be Highly Effective Against MRSA

March 31, 2015 1:37 pm | by Stephanie Guzowski, Editor | News | Comments

British researchers recently found that a thousand-year-old Anglo-Saxon treatment for eye infections works as an antibiotic against MRSA. Read more...

Common Bacteria on Verge of Becoming Antibiotic-Resistant Superbugs

March 26, 2015 1:29 pm | by Michael C. Purdy, Washington Univ. | News | Comments

Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis. Read more...

FDA Approves Anthrax Treatment

March 25, 2015 1:10 pm | by Stephanie Guzowski, Editor | News | Comments

The Food and Drug Administration (FDA) yesterday approved Emergent BioSolutions’ infusible drug Anthrasil for use in combination with antibiotics to treat inhalational anthrax, which happens when bacterial spores that carry anthrax are breathed in. Read more...

Nanotechnology Platform Shows Promise for Treating Pancreatic Cancer

March 24, 2015 12:48 pm | by UCLA | News | Comments

Scientists at UCLA’s California NanoSystems Institute and Jonsson Comprehensive Cancer Center have combined their nanotechnology expertise to create a new treatment that may solve some of the problems of using chemotherapy to treat pancreatic cancer. Read more...

New Hope for Beating Deadly Hereditary Stomach and Breast Cancers

March 20, 2015 10:11 am | by University of Otago | News | Comments

Deadly familial stomach and lobular breast cancers could be successfully treated at their earliest stages, or even prevented, by existing drugs. Read more...

Capturing the Living Picture of Cancer: Proteomic Testing in the Clinical Lab

March 19, 2015 12:46 pm | by Richard Hockett, M.D., Chief Medical Officer at Biodesix, a molecular diagnostics company | Articles | Comments

If genetic sequencing provides the script of life, then proteomics is the live video capturing biology in action. Proteomics moves beyond the static information provided by genomics and tells the story in real-time of proteins, which result from the individual genes within a cell. Read more...

Potential Treatment for Most Common Form of Muscular Dystrophy

March 17, 2015 12:02 pm | by University of Virginia Health System | News | Comments

A doctor who was one of the discoverers of the gene responsible for myotonic muscular dystrophy has now identified a therapeutic that could slow progression of muscle damage and muscle dysfunction associated with the disease – issues that cause patients significant disability and deterioration in quality of life. Read more...

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