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Study Shows Tamiflu Gets Patients Back on Their Feet Faster

January 30, 2015 10:30 am | by University of Michigan | News | Comments

New evidence about a popular antiviral—often criticized as ineffective—shows that it can alleviate symptoms and prevent respiratory complications. Read more...                 

Immune Cells are Ally, Not Enemy, in Battle Against Alzheimer's

January 29, 2015 10:33 am | by Yale University | News | Comments

Beta-amyloid is a sticky protein that aggregates and forms small plaques in the brains of the...

3D Enzyme Model Provides New Tool for Drug Development

January 29, 2015 10:16 am | by UC San Diego | News | Comments

Phospholipase A2 (PLA2) enzymes are known to play a role in many inflammatory diseases,...

Possible Therapeutic Target for Brain Blood Vessel Disorder

January 28, 2015 11:56 am | by University of Pennsylvania | News | Comments

Tens of millions of people around the world have abnormal, leak-prone sproutings of blood...

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Drug Combo Suppresses Late-Stage Prostate Cancer Growth

January 28, 2015 11:37 am | by Purdue University | News | Comments

Low doses of metformin, a widely used diabetes medication, and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors, a Purdue University study finds. Read more...                          

Neural Spines Operate Like Miniature Neurons

January 26, 2015 11:04 am | by LMU | News | Comments

A recent study by teams of neurobiologists based at LMU and Regensburg addresses the role of the short protrusions called “spines” that form on the dendrites of nerve cells in the mammalian olfactory bulb. Dendrites serve as receptors for signals delivered by the so-called axons of other neurons. Read more...

Study Finds Potential New Drug Target for Lung Cancer

January 26, 2015 10:46 am | by Kentucky University | News | Comments

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a key enzyme and its associated metabolic programming may lead to novel drug development to treat lung cancer. Read more...              

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How Cancer Turns Good Cells to the Dark Side

January 26, 2015 10:39 am | by Rice University | News | Comments

Cancer uses a little-understood element of cell signaling to hijack the communication process and spread, according to Rice University researchers. Read more...                             

Progress in Diabetes Drug Delivery

January 23, 2015 9:23 am | by Rebecca Graham, Science Network WA | News | Comments

A DRUG therapy for diabetes treatment is being developed by an international research team led by WA scientists, which combines an existing anti-diabetic drug with bile acids to improve the drug's delivery and prolong release. Read more...                 

BioMérieux, Astute Medical: Global Agreement to Develop, Market AKI Test

January 22, 2015 9:32 am | News | Comments

This is a semi-exclusive agreement regarding the development of a test for the early risk assessment of acute kidney injury (AKI). Read more...                    

NIH Researchers Tackle Thorny Side of Gene Therapy

January 21, 2015 10:05 am | by NIH | News | Comments

National Institutes of Health researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted research on mice with a rare disease similar to one in humans, hoping their findings may eventually help improve gene therapy for humans. Read more...

'Fight or Flight' Response Control Center for Heart Found

January 20, 2015 12:53 pm | by Johns Hopkins University | News | Comments

An animal study led by Johns Hopkins investigators has uncovered what controls the ability of healthy hearts to speed up in response to circumstances ranging from fear to a jog around the block. Read more...                

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Researchers Make Breakthrough on New Anesthetics

January 20, 2015 12:30 pm | by American Society of Anesthesiologists | News | Comments

For the first time since the 1970s, researchers are on the verge of developing a new class of anesthetics. According to a study published in the February issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists (ASA), a new approach to identifying compounds may lead to the next generation of anesthetics. Read more...

New Hope for Restoring Cells in Damaged Brains, Spinal Cords

January 20, 2015 12:26 pm | by Barbara K. Kennedy , Penn State | News | Comments

What motivates Penn State scientists and their students to devote countless hours trying to solve tough research mysteries? For Gong Chen, a biology professor at Penn State, the answer is rooted in a desire to help relieve the suffering of patients and their loved ones. Read more... 

Immunotherapy Inhibits Heroin Effects in Research Animals

January 20, 2015 9:34 am | by Norwegian Institute of Public Health | News | Comments

Immunotherapy could have a place in the treatment of substance abuse in the future. Read more...                            

Flu News: On the Road to a Universal Vaccine

January 16, 2015 12:13 pm | by Stephanie Guzowski, Editor | Articles | Comments

In early December 2014, the Centers for Disease Control and Prevention (CDC) held a briefing in which the agency announced that the current strain of the virus has mutated, rendering this year’s flu vaccine not as effective. The ideal protective approach against flu is a universal vaccine that targets antigens common to all strains of flu. Read more...

Scientists Find How Many Cancers May Evade Treatment

January 16, 2015 10:57 am | by University of Wisconsin-Madison | News | Comments

The drugs were designed to keep cancer cells at bay by preventing their growth, survival and spread. Yet, after clinical trials, they left scientists scratching their heads and drug developers watching their investments succumb to cancer’s latest triumph. Read more...

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Image Captures How Blood Stem Cells Take Root

January 16, 2015 10:31 am | by Nancy Fliesler, Boston Children's Hospital Communications | News | Comments

A see-through zebrafish and enhanced imaging provide the first direct glimpse of how blood stem cells take root in the body to generate blood. Read more...                             

Testing for Bovine TB More Effective Than Badger Culls at Controlling Disease

January 16, 2015 9:32 am | by Queen Mary University of London | News | Comments

The model showed that regular and frequent testing of cattle could eventually lead to the eradication of the disease. Read more...                      

Scientists Discover Protective Cooling of the Brain Could Lead to New Drug Target

January 15, 2015 9:51 am | by University of Leicester | News | Comments

The team discovered that this protective process may be defective in neurodegenerative diseases such as Alzheimer’s. Read more...                      

Study Reveals Lack of Data on Opioid Drugs

January 14, 2015 9:35 am | by University of Connecticut | News | Comments

Many of the studies used to justify the prescription of these drugs were either poorly conducted or of an insufficient duration. Read more...                    

Techniques for RNA Detection in Live Cells

January 13, 2015 4:34 pm | by Martin J. Stoddart, Ph.D. Principal Scientist, Musculoskeletal Regeneration AO Research Institute Davos and Don Weldon R&D Manager EMD Millipore Corporation | Articles | Comments

RNA plays a key regulatory role in cell and tissue development as well as during disease progression. By studying RNA, researchers can advance the understanding of gene expression patterns and determine the roles of genomic elements in cellular function and dysfunction. Read more...

In the News: Open Access Journals

January 13, 2015 8:55 am | by Drug Discovery & Development Staff | Articles | Comments

A number of open access journals have made the news recently. The preprint open access archive, arXiv.org, run by Cornell University, is often used by scientists, from physicists to quantitative biologists, to get their ideas out there quickly and stake out their intellectual ground, before they enter the slow process of peer review. Read more...

Scientists Illuminate Molecular Mechanism Powering Cells

January 9, 2015 10:53 am | by Scripps Institute | News | Comments

A team led by structural biologists at The Scripps Research Institute (TSRI) has taken a big step toward understanding the intricate molecular mechanism of a metabolic enzyme produced in most forms of life on Earth. Read more...               

World-First Stem Cell Clinical Trials in 2014

January 9, 2015 10:02 am | by Drug Discovery & Development Staff | Articles | Comments

The year 2014 saw many world-firsts in the stem cell field, from the creation of human eggs and sperm from adult cells as reported in Cell, to the discovery reported in Science that a single protein (GDF11) in young blood can reverse aging processes in both stem, and terminally differentiated, cells of brain and muscle. Read more...

Snail Venom Sting in Tail of Cancer, Addiction

January 8, 2015 10:16 am | by University of Queensland | News | Comments

Cone snail venom has given University of Queensland researchers a lead on the possible detection and treatment of some cancers and addictions. Read more...                                  

New Clues: Why Older Women Are More Susceptible to Breast Cancer

January 8, 2015 9:05 am | by Skip Derra, Contributing Writer | Articles | Comments

The idea that breast cancer becomes more prevalent with age is fairly well established, but the reasons why are still uncertain. Now, scientists from the Lawrence Berkeley National Laboratory have new insights into why older women are more susceptible to breast cancer. Read more...

Two New Stem Cell Techniques and Clinical Trials for Cornea Damage

January 7, 2015 10:33 am | by Cynthia Fox, Science Editor | Articles | Comments

In recent months, two groups have found two different new ways to regenerate damaged corneas with patients’ own stem cells. Read more...                                     

Toxic Tau Could be Key to Alzheimer’s Treatment

January 6, 2015 8:50 am | by Stephanie Guzowski, Editor | Articles | Comments

For years, Alzheimer’s researchers have targeted amyloid beta in attempts to halt the progression of the disease, without success. Now, they have their sights set on a second brain protein: tau. And the findings are promising. Read more...

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