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FDA Approves Myriad's PARP Inhibitor for Ovarian Cancer

December 19, 2014 2:08 pm | News | Comments

Myriad Genetics, Inc. announced that it has received approval from the U.S. Food and Drug Administration (FDA) for BRACAnalysis CDx to be used as the only companion diagnostic in conjunction with AstraZeneca’s drug Lynparza (olaparib). Read more...

After Lung Transplant, Antiviral Drug Resistance More Likely in Cystic Fibrosis

December 19, 2014 1:50 pm | News | Comments

A drug called ganciclovir is given to lung transplant patients to protect against a life-...

Putting the Breaks on Cancer

December 19, 2014 1:38 pm | News | Comments

A study led by the University of Dundee, in collaboration with the University of Bath, has...

Combo Drug Therapy Doubles Positive Effect for Women with Breast Cancer

December 19, 2014 1:20 pm | News | Comments

In a groundbreaking study that offers new hope for women with advanced breast cancer, UCLA...

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Company Pioneers High Performance Anti-Pruritus Nanopatch

December 19, 2014 10:06 am | News | Comments

A Hong Kong company successfully developed and registered the world's first ever high-performance anti-pruritus nanopatch. Read more...                     

Merck Buys Swiss Biotech Firm With Promising Cancer Drug

December 19, 2014 8:50 am | News | Comments

Merck is buying a biotech company based in Switzerland that is making a promising cancer drug. Read more...                          

New Report: Hep C's Decades of Drug Research Failures, Successes

December 18, 2014 5:18 pm | by PhRMA | News | Comments

PhRMA released a new report, "Twenty-Five Years of Progress Against Hepatitis C: Setbacks and Stepping Stones," that examines the scientific challenges and setbacks researchers have faced on the path to developing new medicines with the potential to transform treatment for hepatitis C patients and how these so-called "failures" are an integral part of the drug discovery process. Read more...

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10 Up-and-Coming Healthcare Medical Innovations

December 18, 2014 12:10 pm | by Christina Jakubowski, Managing Editor, Bioscience Technology | Articles | Comments

The Cleveland Clinic recently unveiled their annual Top 10 Medical Innovations for 2015– a list that casts an optimistic light on up-and-coming healthcare advances that may reach consumers next year. Their number one? Read more...                         

New Disease Mechanism Discovered in Lymphoma

December 18, 2014 11:34 am | by Technical University - Munich | News | Comments

Programmed cell death is a mechanism that causes defective and potentially harmful cells to destroy themselves. It serves a number of purposes in the body, including the prevention of malignant tumor growth. Read more...                          

Warehouse Holding Ebola Supplies in Guinea Catches Fire

December 18, 2014 11:28 am | by Boubacar Diallo - Associated Press | News | Comments

A Guinean official says a fire at a warehouse at the Conakry airport has destroyed crucial medicine to help fight Ebola. Dr. Moussa Konate, head of logistics for Guinea's Ebola response, said that the fire on Thursday morning engulfed a building holding medicine, like anti-malarials and antibiotics. Read more...

Hypertension Medication that Targets Stress May Help Smokers Quit

December 18, 2014 11:23 am | by Daniel Jones, Yale University | News | Comments

Smokers trying to quit often light up a cigarette to deal with stress. Now an interdisciplinary team of Yale researchers has shown that guanfacine, a medication approved for treating hypertension that reduces stress and enhances cognition, shows promise as a smoking cessation aid. Read more...

Microcapsule Eliminates Toxic Punch of Experimental Anti-Cancer Drug

December 18, 2014 11:15 am | by Johns Hopkins | News | Comments

Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates the toxicity of an anticancer agent developed a decade ago at Johns Hopkins, called 3-bromopyruvate, or 3BrPA, in studies of mice with implants of human pancreatic cancer tissue. Read more..

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Enamine, Sanofi Extend Early Drug Discovery Collaboration

December 18, 2014 9:06 am | News | Comments

Enamine and Sanofi extend partnership for early drug discovery. Read more...                               

GSK Shingles Vaccine Hits Goal in Major Study

December 18, 2014 9:02 am | News | Comments

GSK announced that a pivotal phase 3 study to assess the efficacy of HZ/su, an investigational vaccine for the prevention of shingles, has met its primary endpoint. Read more...                                 

New Generation of Cancer Drugs Granted European Approval

December 18, 2014 8:26 am | by University of Cambridge | News | Comments

A new drug for ovarian cancer has become the first of new class of drugs to be granted approval anywhere in the world. Read more...                      

Fresh Setback For Efforts to Cure HIV Infection

December 18, 2014 8:12 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Researchers are reporting another disappointment for efforts to cure infection with the AIDS virus. Read more...                         

Chikungunya Virus Shuts Down Infected Cells

December 17, 2014 4:59 pm | by Wageningen University | News | Comments

Researchers from Wageningen University, part of Wageningen UR, in collaboration with colleagues from Leiden University and a research team in Australia, have revealed how chikungunya virus blocks essential processes in infected cells that normally would keep the virus under control. Read more...

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Despite Risks, Benzodiazepine Use Highest in Older People

December 17, 2014 4:50 pm | by NIH | News | Comments

Prescription use of benzodiazepines — a widely used class of sedative and anti-anxiety medications — increases steadily with age, despite the known risks for older people, according to a comprehensive analysis of benzodiazepine prescribing in the United States. Read more...

Stem Cell Prompting Deadly Fibrosis Found

December 17, 2014 4:35 pm | by Cynthia Fox, Science Writer | Articles | Comments

Some 45% of deaths are caused by fibrosis (scar tissue) diseases, including idiopathic pulmonary fibrosis, cirrhosis, and heart and kidney failure. But a Harvard University group reports in Cell Stem Cell they have discovered a key cause of that fibrosis: a stem-cell-like perivascular cell called Gli1+, found in blood vessels. Read more...

Study: Removing Clot Helps Limit Stroke Disability

December 17, 2014 2:25 pm | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

A new treatment has been shown to limit the damage from a common type of stroke. Read more...                           

Napster Co-Founder Makes Investment in Allergy Research

December 17, 2014 2:03 pm | by Olga R. Rodriguez - Associated Press | News | Comments

The former Facebook president said he wants to help find a lasting cure to allergies. Read more...                           

New Insight Into How Motor Neurons in Brain Die During ALS

December 17, 2014 12:33 pm | News | Comments

Researchers look to understand the causes of amyotrophic lateral sclerosis (ALS), in the hope of finding new ways to treat the disease. A new study published online in the Cell Press journal Neuron shows that a common gene mutation in ALS generates a deadly protein that may cause the damage in the brain that leads to ALS. Read more...

Ohio House to Consider Lethal Injection Drug Bill

December 17, 2014 12:22 pm | News | Comments

The names of companies that provide Ohio with lethal injection drugs would be shielded under a proposal the state House is poised to vote on Wednesday. Read more...                                        

Occasional Heroin Use May Worsen HIV Infection

December 17, 2014 12:15 pm | News | Comments

Researchers at Yale and Boston University and their Russian collaborators have found that occasional heroin use by HIV-positive patients may be particularly harmful to the immune system and worsens HIV disease, compared to persistent or no heroin use. Read more...

PDI Announces Launch of NGS Test for Cancer Risk Assessment

December 17, 2014 12:07 pm | News | Comments

PDI, Inc. announced that its molecular diagnostics subsidiary, Interpace Diagnostics, has launched its new next-generation sequencing (NGS) ThyGenX test to assist physicians in distinguishing between benign and malignant genotypes in indeterminate thyroid nodules.  Read more...

FDA Approves First Pathogen Reduction System to Treat Plasma

December 17, 2014 12:02 pm | News | Comments

The U.S. Food and Drug Administration today approved the Intercept Blood System for plasma, the first pathogen reduction system for use by blood establishments in the preparation of plasma in order to reduce the risk of transfusion-transmitted infections (TTI). Read more...

Predicting Antibiotic Resistance

December 17, 2014 10:14 am | News | Comments

Treating bacterial infections with antibiotics is becoming increasingly difficult as bacteria develop resistance to the antibiotics being used against them. Read more...                

Clementia Launches First Natural History Study of Patients with FOP

December 17, 2014 10:04 am | News | Comments

Clementia Pharmaceuticals announced the initiation of a natural history study in patients with fibrodysplasia ossificans progressiva. Read more...                   

House Searches for Ebola in Sierra Leone Capital

December 17, 2014 9:25 am | by Clarence Roy-Macaulay - Associated Press | News | Comments

Surveillance teams fanned out Wednesday in Sierra Leone's capital to search every house for sick people. Read more...                        

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