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Breaking News: Cubist Recalls Cubicin Lot

April 18, 2014 2:02 pm | News | Comments

Cubist Pharmaceuticals Inc. announced it is voluntarily recalling one lot of Cubicin (daptomycin for injection) to the user level due to the presence of particulate matter, reported via customer complaint and identified as glass particles. Read more...

Top French Advisor Resigns Amid Drug Industry Scandal

April 18, 2014 1:06 pm | News | Comments

Aquilino Morelle, the French president's top adviser...

Washington University Launches Immunology Center

April 18, 2014 12:54 pm | by Michael Purdy | News | Comments

A new center at Washington University School of Medicine in St. Louis - ...

New Pain Relief Targets Could Benefit Cancer Patients

April 18, 2014 12:36 pm | News | Comments

When researching how pain occurs in nerves in the periphery...

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Phase 1/2 Results Positive for Cancer Drug

April 18, 2014 12:20 pm | News | Comments

XBiotech is announcing that results from its Phase 1/2 oncology study conducted at MD Anderson Cancer Center in Houston, TX were published in Lancet Oncology, which describes the outcome in 52 advanced cancer patients treated with Xilonix, XBiotech’s anti-tumor therapy. Read more...

Ivabradine Fast Tracked for Chronic HF

April 18, 2014 12:13 pm | News | Comments

The U.S. Food and Drug Administration (FDA) has granted fast track designation for investigational ivabradine - an oral drug that inhibits the If current (“funny” current) in the sinoatrial node, the body’s cardiac pacemaker - for patients with chronic heart failure (HF). Read more...

FDA Approves Arzerra for Chronic Lymphocytic Leukemia

April 18, 2014 12:03 pm | News | Comments

GlaxoSmithKline and Genmab announced that the FDA has approved a supplemental BLA for the use of Arzerra, a CD20-directed cytolytic monoclonal antibody, in combination with chlorambucil for the treatment of previously untreated patients with chronic lymphocytic leukemia. Read more...

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Anti-Seizure Drug Could Reduce Alcohol Consumption

April 18, 2014 10:34 am | News | Comments

Researchers have discovered that the anti-seizure drug ezogabine, reduced alcohol consumption in an experimental model. The findings may lead to more effective treatments for alcoholism. Read more...               

Multi-Target TB Drug May Treat Other Diseases, Evade Resistance

April 18, 2014 9:53 am | News | Comments

A drug under clinical trials to treat tuberculosis could be the basis for a class of broad-spectrum drugs that act against various bacteria, fungal infections and parasites, yet evade resistance, according to a new study. Read more...     

NIH Awards Scripps $2M to Design a Better Diabetes Drug Model

April 17, 2014 1:21 pm | News | Comments

Scientists from the Florida campus of TSRI have been awarded $2.1 million from the NIH to study the therapeutic potential of safer and more effective alternatives to the current crop of anti-diabetic drugs, which have been limited in their use due to side effects including bone loss and CHF. Read more...

Finding Suggests New Possibilities for Oncology and Virology

April 17, 2014 1:06 pm | News | Comments

Scientists at Washington University School of Medicine in St. Louis have uncovered a new way the immune system may fight cancers and viral infections, which could aid efforts to use immune cells to treat illness. Read more...     

Sanguine, Mayo Clinic Agreement Furthers Personalized Medicine

April 17, 2014 12:40 pm | News | Comments

Sanguine announced an agreement with Mayo Clinic Bioservices, under which Mayo Clinic Bioservices will process, store and ship biospecimens that Sanguine has collected. Read more...                   

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New Gene Technology Has Therapeutic Implications

April 17, 2014 12:16 pm | News | Comments

For thousands of years humans have been tinkering with plant genetics, even when they didn’t realize that is what they were doing, in an effort to make stronger, healthier crops that endured climates better, and produced more. Read more...   

VentiRx Completes Enrollment in Study of Orphan Cancer Drug

April 17, 2014 11:47 am | News | Comments

VentiRx Pharmaceuticals Inc. announced that enrollment has been completed in a Phase 2 trial of VTX-2337 in combination with pegylated liposomal doxorubicin in patients with recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer who have failed prior platinum-based chemotherapy. Read more...

GSK Reports More Bribery Inquiries

April 17, 2014 11:24 am | News | Comments

British drugmaker GlaxoSmithKline is looking into allegations of bribery within its operations in Jordan and Lebanon. The company is also facing a corruption investigation in China and a bribery investigation in Poland and is looking into alleged bribery in Iraq. Read more...

A Cinderella Story: Stem Cells in Personalized Medicine

April 17, 2014 11:00 am | Videos | Comments

In part four of our video series, Andrew Wiecek is back to discuss the role that induced pluripotent stem (iPS) cells play in personalized medicine. How do they help? Well, iPS cells are kind of like Cinderella's glass slipper. Watch more...

'Matrix' Trial Will Advance Personalized Medicine for Lung Cancers

April 17, 2014 10:52 am | Videos | Comments

The "National Lung Matrix" trial, a partnership between Cancer Research UK, AstraZeneca and Pfizer, will give researchers unprecedented access to libraries of drugs developed by the companies, allowing several to be tested at the same time, within one trial. Read more...

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Cancer Drugs Block Dementia-Linked Brain Inflammation

April 17, 2014 10:40 am | News | Comments

A class of drugs developed to treat immune-related conditions and cancer– including one currently in clinical trials- eliminates neural inflammation associated with dementia-linked diseases and brain injuries, according to researchers. Read more...

Vaccine Offers Survival Hope for Melanoma Patients

April 17, 2014 10:29 am | News | Comments

Researchers have discovered that a new trial vaccine offers the most promising treatment to date for melanoma that has spread, with increased patient survival rates and improved ability to stop or reverse the cancer. Read more...      

HPV Vaccine Works in HIV+ Women

April 16, 2014 2:00 pm | News | Comments

HIV-positive women respond well to a vaccine against the human papillomavirus (HPV), even when their immune system is struggling, according to newly published results of an international clinical trial, countering doubts about whether the vaccine would be helpful. Read more...

Measles Drug Lowers Viral Load

April 16, 2014 2:00 pm | News | Comments

A novel antiviral drug may protect people infected with the measles from getting sick and prevent them from spreading the virus to others, an international team of researchers said. Read more...                  

Phase 1 Results Positive for Tumor Vaccine

April 16, 2014 2:00 pm | News | Comments

Celldex Therapeutics Inc. announced that final data from its Phase 1 study of CDX-1401 (an off-the-shelf vaccine that targets dendritic cells) in solid tumors, including long-term patient follow-up, have been published in Science Translational Medicine. Read more...

Small Molecule Shows Potential in Advanced Cancers

April 16, 2014 1:34 pm | News | Comments

Cleveland BioLabs Inc. announced the achievement of all objectives in a Phase 1 clinical trial of CBL0102, or quinacrine, an orally administered small molecule in patients with advanced cancers for which no standard care exists or which had become resistant to conventional therapies. Read more...

Baxter's Orphan Drug Candidate Hits Key Phase 3 Endpoint

April 16, 2014 1:06 pm | News | Comments

Baxter International Inc. announced topline results from a Phase 3 clinical trial evaluating the safety, efficacy and pharmacokinetics of BAX 111, a recombinant von Willebrand factor under investigation for the treatment of bleeding episodes in patients with von Willebrand disease. Read more...

Researchers ID New Formulation for Cancer Treatment

April 16, 2014 11:20 am | News | Comments

Researchers have discovered a new way to deliver a tricky drug, dichloroacetate, that may one day make it a viable treatment for numerous forms of cancer. Read more...                       

3-D Printed Tissues May Aid Drug Delivery, Wound Healing

April 16, 2014 11:13 am | News | Comments

A University of Oxford spin-out, OxSyBio, will develop 3-D printing techniques to produce tissue-like synthetic materials for wound healing and drug delivery. Read more...                       

Drug Developers Using New Models, Methods to Boost Clinical Success Rates

April 16, 2014 11:05 am | News | Comments

Drug companies and their development partners who are seeking to increase clinical success rates of new drug candidates are developing tools to help them predict the likelihood of marketing approval and incorporating business planning earlier in clinical development, according to new evidence. Read more...

SSRI Use During Pregnancy Linked to Autism, Developmental Delays

April 16, 2014 10:57 am | News | Comments

In a study of nearly 1,000 mother-child pairs, researchers found that prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) was associated with autism spectrum disorder (ASD) and developmental delays (DD) in boys. Read more...   

Judge Blocks Zohydro Ban in Massachusetts

April 16, 2014 10:47 am | by Steve LeBlanc | News | Comments

A federal judge has blocked Massachusetts from banning the powerful new painkiller Zohydro after the maker of the drug, Zogenix, argued in a lawsuit that the ban ordered by Gov. Deval Patrick last month is unconstitutional. Read more...    

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