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Neurotrope: Last Patient Dosed in Phase 2a Alzheimer's Study

November 21, 2014 11:41 am | News | Comments

Neurotrope, Inc. announced that the last patient has been dosed in its Phase 2a clinical trial of Bryostatin-1 for the treatment of patients with Alzheimer's disease (AD). The trial is being conducted under an Investigational New Drug (IND) application filed by the Company's licensor, the Blanchette Rockefeller Neuroscience Institute (BRNI). Read more...

Maximizing the Power of Preclinical Cancer Research Tools

November 19, 2014 11:29 am | by Guizhong Liu, Senior Director of Cancer Biology, Crown Bioscience Inc. | Articles | Comments

Drug discovery is...

Anti-Leukemia Drug May Also Work Against Ovarian Cancer

November 18, 2014 1:50 pm | News | Comments

An antibody...

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Preferred Drug Regimen for Preventing Mother-to-Child HIV Transmission

November 18, 2014 10:14 am | News | Comments

For HIV-infected women in good immune health, taking a three-drug regimen during pregnancy prevents mother-to-child HIV transmission more effectively than taking one drug during pregnancy, another during labor and two more after giving birth, an international clinical trial has found. Read more...

Roche Announces FDA Approval of Ovarian Cancer Treatment

November 17, 2014 1:30 pm | News | Comments

The FDA approves Roche's ovarian cancer treatment. Read more...                                 

Eisai's Antiepileptic Treatment Receives Russian Approval

November 17, 2014 10:34 am | News | Comments

Eisai Pharmaceuticals announces Russian approval of antiepileptic treatment. Read more...                             

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Oxford to Lead Trial of Experimental Drug for Ebola

November 14, 2014 10:07 am | News | Comments

A clinical trial is to be carried out in West Africa to see whether a novel antiviral drug is effective against Ebola. Read more...                       

'Smart' Drugs Won't Make Smart People Smarter

November 13, 2014 12:46 pm | News | Comments

It is claimed one in five students have taken the 'smart' drug Modafinil to boost their ability to study and improve their chances of exam success. But new research into the effects of Modafinil has shown that healthy students could find their performance impaired by the drug. Read more...

Improved Survival in Women with HER2 Negative Breast Cancer

November 13, 2014 9:22 am | News | Comments

The results from a pooled analysis of two Phase 3 Halaven (eribulin) trials are published in Breast Cancer Research and Treatment. Findings from the pooled analysis show that eribulin improves overall survival in women compared to control. Read more...

Fighting HIV with Stem Cells and Cutting-edge Genetics

November 11, 2014 10:51 am | by Cynthia Fox, Science Editor | Articles | Comments

“Berlin Patient” Timothy Brown was cured of HIV after he received stem cells from a patient naturally immune to the disease. His story inspired two companies to try and recreate that natural immunity in HIV patients using stem cells and two (then-new) gene-editing techniques. Read more...

Gilead's Hep C Drug Gets Positive Results

November 11, 2014 10:09 am | News | Comments

Gilead Sciences Inc. announced results from several Phase 2 and Phase 3 studies evaluating investigational uses of Harvoni (ledipasvir 90 mg/sofosbuvir 400 mg) for the treatment of chronic hepatitis C virus (HCV) infection in patients with limited or no treatment options. Read more...

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BMS Announces High Cure Rates for Hepatitis C Drug

November 10, 2014 10:42 am | News | Comments

Bristol-Myers Squibb announced late-breaking data regarding a new drug combination for Hepatitis C patients. Read more...                       

New Drug for Common Liver Disease May Improve Liver Health

November 7, 2014 12:52 pm | News | Comments

An experimental drug aimed at treating a common liver disease showed promising results and potential problems in a multicenter clinical trial funded by the National Institutes of Health.  Read more...

Funding Speeds Drugs Identification For Alzheimers Prevention

November 6, 2014 1:13 pm | News | Comments

The National Institutes of Health has boosted funding for the first large-scale clinical trial aimed at identifying drugs to stop or slow Alzheimer’s disease in people destined to get the debilitating illness. Read more...       

AFib Blood Thinner Has Higher GI Risk

November 5, 2014 1:33 pm | News | Comments

Patients with atrial fibrillation who take the blood thinner dabigatran are at greater risk for major bleeding and gastrointestinal bleeding than those who take warfarin, according to a new study by researchers at the University of Pittsburgh Graduate School of Public Health. Read more...

Melanoma Survival Better With Immune Booster

November 5, 2014 1:11 pm | News | Comments

Patients with metastatic melanoma who were treated with ipilimumab, an immune checkpoint blocker, survived 50% longer – a median 17.5 months vs. 12.7 months – if they simultaneously received an immune stimulant, according to a study led by Dana-Farber Cancer Institute scientists. Read more...

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GSK Submits European, US Filings for Asthma Med

November 5, 2014 10:14 am | News | Comments

GlaxoSmithKline announced that it has filed regulatory submissions in the USA and Europe for mepolizumab for approval as a maintenance treatment for patients with severe eosinophilic asthma. Read more...          

BRCA-Targeting Drugs Could Treat Prostate Cancer

November 5, 2014 9:31 am | News | Comments

A pioneering cancer drug set to become the first to be approved specifically for inherited cancers could also be used much more widely to treat prostate cancer. Read more...               

Using Real-World Data for Outcomes Research and Comparative Effectiveness Studies

November 4, 2014 10:17 am | by Christina Mack, Ph.D., MSPH, Associate Director, Epidemiology, Real-World & Late Phase Research, Quintiles, and Kathy Lang, Ph.D., Senior Director, Emerging Businesses Data & Analytics, Real-World & Late Phase Research, Quintiles | Articles | Comments

Biopharma is increasingly harnessing the power of data collected outside of a controlled clinical environment to generate valuable insights to support products throughout their lifecycle. Read more...

First Human Clinical Trial of 'C dots' Highlights Safety

October 31, 2014 2:14 pm | News | Comments

A first clinical trial of these ultrasmall, multifunctional particles has deemed them safe for humans and cleared easily by the body. Read more...                   

Special Report: Many Stem Cell Clinical Trials for Macular Degeneration

October 31, 2014 11:22 am | by Cynthia Fox, Science Editor | Articles | Comments

The most potent stem cells are coming to patients after helping blind (and nearly blind) mice see for years. Read more...                                                                                

NeuroDerm Announces Positive Phase 2 Results of Parkinsons Vaccine

October 30, 2014 9:49 am | News | Comments

NeuroDerm announced positive phase 2 results for a new Parkinsons vaccine. Read more...                             

ESMO: Cancer Immunotherapy on the Road

October 29, 2014 12:20 pm | by Neil Canavan | Articles | Comments

Since cancer immunotherapy was declared the Breakthrough of the Year in 2013 by Science magazine the field has been on fire, and its relatively few experts have been on the run– explaining the nascent technology and related data to oncologists at venues from the April meeting of AACR in San Diego, to the June meeting of ASCO in Chicago, to the September meeting of ESMO in Madrid.  Read more...

Scripps MS Drug Candidate Shows Promise for UC

October 28, 2014 12:10 pm | News | Comments

Positive new clinical data were released on a drug candidate for ulcerative colitis that was first discovered and synthesized at The Scripps Research Institute. Read more...              

New Trial Will Explore Heart Disease Prevention in People with HIV

October 28, 2014 9:44 am | News | Comments

The National Institutes of Health and The National Heart, Lung and Blood Institute are initiating a landmark multimillion dollar outcomes trial utilizing pitavastatin for the primary prevention of cardiovascular disease in persons infected with HIV. Read more... 

BMS Acquires Worldwide Rights For New Breast Cancer Therapy

October 28, 2014 8:57 am | News | Comments

Bristol-Myers Squibb Company entered into an agreement F-star Alpha to acquire the company and gain worldwide rights to a targeted therapy that can treat breast and gastric cancer. Read more...           

Baxter Announces FDA Approval For New Hemophilia Drug

October 24, 2014 12:27 pm | News | Comments

Baxter International Inc. announced that the FDA has approved Obizur for the treatment of bleeding episodes in adults with acquired hemophilia A. Read more...                           

Study Finds Best Way to Treat Neck Pain

October 24, 2014 10:03 am | News | Comments

A multicenter study of 169 men and women with a common form of neck pain suggests that both spinal steroid injections and conservative treatment with physical therapy and painkillers work equally well to relieve pain in the short term. Read more...  

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