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Roseroot Shows Promise as Potential Depression Treatment Option

March 27, 2015 10:27 am | by Penn University | News | Comments

Rhodiola rosea (R. rosea), or roseroot, may be a beneficial treatment option for major depressive disorder (MDD), according to results of a study in the journal Phytomedicine. Read more...

HIV Replicates in Brain Earlier than Thought: Study

March 26, 2015 2:05 pm | by Stephanie Guzowski, Editor | News | Comments

A recent study, funded by the National Institutes of Health (NIH), highlights the importance of...

Men’s Heart Disease Partly Due to Low Estrogen

March 26, 2015 8:52 am | by Cynthia Fox, Science Writer | Articles | Comments

One reason men have more heart disease than women is the very fact that they are men,...

Sanofi Announces Top-Line Results for Study of Lyxumia

March 19, 2015 4:32 pm | News | Comments

Full results will be presented at the American Diabetes Association 75th Scientific Sessions in...

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World-First Cancer Drugs Could Work in Larger Group of Patients

March 19, 2015 4:22 pm | by Institute of Cancer Research | News | Comments

A pioneering class of drugs that target cancers with mutations in the BRCA breast cancer genes could also work against tumors with another type of genetic fault. Read more...

Study Suggests Precision Medicine for Adrenal Cancer

March 18, 2015 10:57 am | by University of Michigan | News | Comments

Despite overall lack of success, small subset of patients responds to investigational drug. Read more...

Sickle Cell Drug Offers “Overwhelming” Gains as “Exciting” Stem Cell Trial Starts

March 16, 2015 3:58 pm | by Cynthia Fox, Science Editor | Articles | Comments

A clinical trial of the most common sickle cell anemia drug, hydroxyurea, was halted a year early this winter because of “overwhelming evidence of benefit,” reported University of Nebraska Medical Center pediatric researcher Stephen Obaro, M.D., Ph.D., in The Lancet. Read more...

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Amgen's Cholesterol-Lowering Repatha Shows Positive Data

March 16, 2015 10:19 am | News | Comments

Amgen announced new detailed data from the Phase 3 YUKAWA-2 study evaluating Repatha (evolocumab), a novel investigational cholesterol-lowering medication, in Japanese patients with high cardiovascular risk and high cholesterol.  Read more...

Anti-Herpes Drug May Help Control HIV

March 13, 2015 1:56 pm | by Stephanie Guzowski, Editor | News | Comments

A drug that’s used to control herpes simplex virus 2 (HSV-2) could reduce levels of HIV in patients who do not have genital herpes, finds a National Institutes of Health (NIH) study. Read more...

Diabetes Drug Shown Not to Increase Heart Failure Risk

March 13, 2015 12:17 pm | by University of Connecticut | News | Comments

People with the most common form of diabetes can take the new drug Alogliptin without concern for an increased risk of heart failure or cardiovascular disease, according to research by a UConn cardiologist published in the British medical journal, The Lancet. Read more..

FDA Approves Pediatric Cancer Drug

March 11, 2015 4:24 pm | by Stephanie Guzowski, Editor | News | Comments

The U.S. Food and Drug Administration (FDA) has approved Unituxin (dinutuximab), part of a first-line therapy for high-risk neuroblastoma. Read more..                                  

Investigational Therapy Could Attack Cause of Sickle Cell Crises

March 3, 2015 11:47 am | News | Comments

Treatment for painful episodes of blood vessel obstruction in sickle cell anemia is currently limited to controlling pain, but an investigational therapy might be able to interfere with the underlying cause of these events, known as vaso-occlusion crises, researchers at Duke Medicine report. Read more...

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Amgen Announces Results of Phase 3 Head-to-Head Study of Drugs for Multiple Myeloma

March 2, 2015 12:59 pm | News | Comments

Patients receiving one of the medications that was tested lived twice as long without disease progression. Read more...                       

Sanofi Gets FDA Approval for New Insulin Drug

February 26, 2015 12:06 pm | by Stephanie Guzowski, Editor | News | Comments

Sanofi announced late Wednesday that it received approval from the U.S. Food and Drug Administration (FDA) to sell its new insulin product Toujeo. The once-daily, long-acting basal insulin will help improve glycemic control in adults with type 1 and type 2 diabetes. Read more..

First Independent U.S. Psoriasis Registry Will Track Drug Safety

February 26, 2015 11:09 am | News | Comments

People with psoriasis and their health care providers will have the opportunity to participate in research that aims to improve treatments and disease outcomes when the first independent U.S. psoriasis registry begins recruiting patients in 2015. Read more...

Amgen: Positive Results for CKD Treatment

February 26, 2015 11:05 am | News | Comments

Amgen announced results from the head-to-head Phase 3 study comparing AMG 416 with cinacalcet for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) receiving hemodialysis. Read more...

Skin Test May Shed Light on Alzheimer's, Parkinson's

February 25, 2015 10:53 am | by American Academy of Neurology | News | Comments

Scientists have discovered a skin test that may shed new light on Alzheimer's and Parkinson's diseases, according to a study released will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, D.C., April 18 to 25, 2015. The study showed that skin biopsies can be used to detect elevated levels of abnormal proteins found in the two diseases.

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FDA Approves Novartis' HDAC Inhibitor for Multiple Myeloma

February 24, 2015 3:23 pm | News | Comments

This inhibitor is the first of its kind for multiple myeloma. Read more...                               

Asthma Drug Improves Lung Function: Phase 3 Data

February 23, 2015 10:13 am | News | Comments

Boehringer Ingelheim today presented data on investigational tiotropium delivered via Respimat inhaler from five Phase 3 trials from the UniTinA-asthma program at the 2015 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting in Houston, Texas. Read more..

Oral Med Shows Promise in Hormone-Resistant Breast Cancer

February 23, 2015 10:03 am | News | Comments

​Palbociclib, an investigational oral medication that works by blocking molecules responsible for cancer cell growth, is well tolerated and extends progression-free survival (PFS) in newly diagnosed, advanced breast cancer patients, including those whose disease has stopped responding to traditional endocrine treatments. Read more...

Lilly Provides Update on Evacetrapib Phase 3 Trial

February 20, 2015 12:25 pm | News | Comments

Eli Lilly and Company has accepted the recommendation of the ACCELERATE study academic executive committee, based on emerging science in the cardiovascular field, to extend the Phase 3 trial of the investigational medicine evacetrapib by approximately six months. Read more....

Evaluating Drugs to Improve Vision In Diabetic Macular Edema

February 20, 2015 12:05 pm | by Marla Paul, Northwestern Univ. | News | Comments

A national study led by Northwestern Medicine shows the drug Eylea is superior for improving the eyesight of persons with poor vision due to diabetic macular edema, a major cause of vision loss from diabetes, according to Lee Jampol, MD, Louis Feinberg, MD, Professor of Ophthalmology. Read more...

Novo Nordisk Announces Positive Phase 2 Results for Type 2 Diabetes Drug Study

February 20, 2015 9:19 am | News | Comments

Novo Nordisk announced that it has successfully completed the phase 2 trial for a treatment for type 2 diabetes. Read more...                      

The Journey to an HIV Vaccine Endures

February 19, 2015 12:46 pm | by Stephanie Guzowski, Editor | Articles | Comments

Despite more than 30 years of efforts, scientists have not yet come up with a reliably effective HIV vaccine — in part, because of the inherently complicated nature of the virus. Here are where their research efforts stand today.

Development of Personalized Cellular Therapy for Brain Cancer

February 19, 2015 9:55 am | by UPenn | News | Comments

Immune cells engineered to seek out and attack a type of deadly brain cancer were found to be both safe and effective at controlling tumor growth in mice that were treated with these modified cells, according to a study published in Science Translational Medicine by a team from the Perelman School of Medicine at the University of Pennsylvania and the Novartis Institutes for BioMedical Research. Read more...

Oncolytics: Enrollment Completion for Phase 2 Randomized Colorectal Cancer Study

February 18, 2015 9:08 am | News | Comments

The trial is being sponsored and conducted by the NCIC Clinical Trials Group. Read more...                            

Lung Cancer Breath Test in Clinical Trial

February 18, 2015 8:55 am | by University of Leicester | News | Comments

A clinical trial exploring a potentially ground-breaking ‘breath test’ to detect lung cancer is set to get underway. Read more...                      

Researchers Test Device to Help Deaf Children Detect Sounds

February 13, 2015 4:48 pm | by Lauran Neergaard, AP Medical Writer | News | Comments

The device goes beyond cochlear implants that have brought hearing to many deaf children but that don't work for tots who lack their hearing nerve. Read more...                 

Closing the Knowledge Gap on Cancer Drug Toxicity

February 12, 2015 3:59 pm | by David Jackson, Ph.D., Chief Innovation Officer, MolecularHealth | Articles | Comments

There is a dangerous knowledge gap in the use of cancer medications that needs to be closed, immediately. Read more...                                                          

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