Almac announced a Qualified Person Facilitation program offered to global clients importing investigational medicinal products into the EU for clinical trials.
Merck & Co. said that its experimental insomnia drug suvorexant helped patients fall asleep faster and stay asleep longer in two late-stage tests of the drug.
Teva Pharmaceutical Industries Ltd. said that a new version of its multiple sclerosis drug Copaxone met its goals in a late-stage clinical trial.
Cancer Research UK’s has begun a clinical trial that will test an experimental drug called AZD4547 in combination with standard chemotherapy for stomach or oesophageal cancer.
While exploratory clinical trials have been proposed for years,interest has boomed since the publication of the ICH M3 R2 guidelines in 2008.
Cobra Biologics and Alligator Bioscience have signed a manufacturing services and supply agreement for the production of monoclonal antibody drug substance and drug product.
Avanir Pharmaceuticals Inc. said it is planning to begin a midstage trial of its drug Nuedexta as a treatment for agitation in Alzheimer's disease patients.
Ampio Pharmaceuticals Inc. has reported positive data from a trial of its eye drug Optina. It said some doses of Optina were significantly more effective than placebo.
High levels of attrition during clinical trials are frequently due to the harmful effects compounds can have on the heart’s electrical activity and function.
The PI3K gene is a key component of the PI3K-AKT-mTOR cell-signaling pathway, which regulates cell metabolism, proliferation, and survival.
Class I phosphatidylinositol 3-kinases have emerged as important cancer drug targets. Class I PI3Ks are heterodimers comprising a catalytic subunit and a regulatory subunit.
The psoriasis and atopic dermatitis markets have historically been dominated by topical steroids, vitamin D analogues, and calcineurin inhibitors; all of which are over 20 years-old.
Abbott announced results from a Phase 3 study of Humira, which assessed the improvement in signs and symptoms of disease for patients with active axial spondyloarthritis.
Rhythm has initiated a Phase 2 clinical trial for RM-131, its novel ghrelin agonist, for the treatment of gastroparesis in patients with Type 1 and Type 2 diabetes.
Some experimental diabetes treatments offer patients hope of better controlling their blood sugar and weight and preventing dangerously low blood sugar.
Genentech announced data showed that rheumatoid arthritis patients who received Actemra experienced a greater improvement than patients who received adalimumab.
Bristol-Myers Squibb announced the results of a Phase 3b clinical trial comparing Orencia to Humira in patients with moderate to severe rheumatoid arthritis.
A recent study has found that patients with active psoriatic arthritis receiving Stelara experienced significant improvements in signs and symptoms of the disease.
ChemoCentryx Inc. announced positive data from its Phase 2 study for CCX354, an orally-administered inhibitor of CCR1, in patients with rheumatoid arthritis.
Abbott and Neurocrine Biosciences have initiated a Phase 3 clinical trial designed to evaluate the safety and efficacy of elagolix in patients with endometriosis.
AFFiRiS AG has begun the world's first clinical trial for a Parkinson´s vaccine, targeting alpha-synuclein—a protein causing onset and progression of the disease—with PD01A.
GlaxoSmithKline has release data from two Phase 3 studies evaluating single-agent therapy with dabrafenib and trametinib in patients with metastatic melanoma.
Immunovaccine Inc. announced results from a Phase 1 clinical trial showing targeted multi-functional immunotherapeutic responses induced by the DPX-0907 vaccine.
OncoGenex Pharmaceuticals Inc. announced data from a Phase 2 study of OGX-427 in chemotherapy-naive metastatic castration resistant prostate cancer patients.