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Daily news and top headlines for drug research professionals

Sanofi Gets FDA Approval for New Insulin Drug

February 26, 2015 12:06 pm | by Stephanie Guzowski, Editor | News | Comments

Sanofi announced late Wednesday that it received approval from the U.S. Food and Drug Administration (FDA) to sell its new insulin product Toujeo. The once-daily, long-acting basal insulin will help improve glycemic control in adults with type 1 and type 2 diabetes. Read more..

First Independent U.S. Psoriasis Registry Will Track Drug Safety

February 26, 2015 11:09 am | News | Comments

People with psoriasis and their health care providers will have the opportunity to participate in research that aims to improve treatments and disease outcomes when the first independent U.S. psoriasis registry begins recruiting patients in 2015. Read more...

Amgen: Positive Results for CKD Treatment

February 26, 2015 11:05 am | News | Comments

Amgen announced results from the head-to-head Phase 3 study comparing AMG 416 with cinacalcet for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) receiving hemodialysis. Read more...

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Skin Test May Shed Light on Alzheimer's, Parkinson's

February 25, 2015 10:53 am | by American Academy of Neurology | News | Comments

Scientists have discovered a skin test that may shed new light on Alzheimer's and Parkinson's diseases, according to a study released will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, D.C., April 18 to 25, 2015. The study showed that skin biopsies can be used to detect elevated levels of abnormal proteins found in the two diseases.

FDA Approves Novartis' HDAC Inhibitor for Multiple Myeloma

February 24, 2015 3:23 pm | News | Comments

This inhibitor is the first of its kind for multiple myeloma. Read more...                               

Asthma Drug Improves Lung Function: Phase 3 Data

February 23, 2015 10:13 am | News | Comments

Boehringer Ingelheim today presented data on investigational tiotropium delivered via Respimat inhaler from five Phase 3 trials from the UniTinA-asthma program at the 2015 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting in Houston, Texas. Read more..

Oral Med Shows Promise in Hormone-Resistant Breast Cancer

February 23, 2015 10:03 am | News | Comments

​Palbociclib, an investigational oral medication that works by blocking molecules responsible for cancer cell growth, is well tolerated and extends progression-free survival (PFS) in newly diagnosed, advanced breast cancer patients, including those whose disease has stopped responding to traditional endocrine treatments. Read more...

Lilly Provides Update on Evacetrapib Phase 3 Trial

February 20, 2015 12:25 pm | News | Comments

Eli Lilly and Company has accepted the recommendation of the ACCELERATE study academic executive committee, based on emerging science in the cardiovascular field, to extend the Phase 3 trial of the investigational medicine evacetrapib by approximately six months. Read more....

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Evaluating Drugs to Improve Vision In Diabetic Macular Edema

February 20, 2015 12:05 pm | by Marla Paul, Northwestern Univ. | News | Comments

A national study led by Northwestern Medicine shows the drug Eylea is superior for improving the eyesight of persons with poor vision due to diabetic macular edema, a major cause of vision loss from diabetes, according to Lee Jampol, MD, Louis Feinberg, MD, Professor of Ophthalmology. Read more...

Novo Nordisk Announces Positive Phase 2 Results for Type 2 Diabetes Drug Study

February 20, 2015 9:19 am | News | Comments

Novo Nordisk announced that it has successfully completed the phase 2 trial for a treatment for type 2 diabetes. Read more...                      

The Journey to an HIV Vaccine Endures

February 19, 2015 12:46 pm | by Stephanie Guzowski, Editor | Articles | Comments

Despite more than 30 years of efforts, scientists have not yet come up with a reliably effective HIV vaccine — in part, because of the inherently complicated nature of the virus. Here are where their research efforts stand today.

Development of Personalized Cellular Therapy for Brain Cancer

February 19, 2015 9:55 am | by UPenn | News | Comments

Immune cells engineered to seek out and attack a type of deadly brain cancer were found to be both safe and effective at controlling tumor growth in mice that were treated with these modified cells, according to a study published in Science Translational Medicine by a team from the Perelman School of Medicine at the University of Pennsylvania and the Novartis Institutes for BioMedical Research. Read more...

Oncolytics: Enrollment Completion for Phase 2 Randomized Colorectal Cancer Study

February 18, 2015 9:08 am | News | Comments

The trial is being sponsored and conducted by the NCIC Clinical Trials Group. Read more...                            

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Lung Cancer Breath Test in Clinical Trial

February 18, 2015 8:55 am | by University of Leicester | News | Comments

A clinical trial exploring a potentially ground-breaking ‘breath test’ to detect lung cancer is set to get underway. Read more...                      

Researchers Test Device to Help Deaf Children Detect Sounds

February 13, 2015 4:48 pm | by Lauran Neergaard, AP Medical Writer | News | Comments

The device goes beyond cochlear implants that have brought hearing to many deaf children but that don't work for tots who lack their hearing nerve. Read more...                 

Closing the Knowledge Gap on Cancer Drug Toxicity

February 12, 2015 3:59 pm | by David Jackson, Ph.D., Chief Innovation Officer, MolecularHealth | Articles | Comments

There is a dangerous knowledge gap in the use of cancer medications that needs to be closed, immediately. Read more...                                                          

Science is Afire With Plans to Help Smokers Quit

February 12, 2015 12:25 pm | by Cynthia Fox, Science Editor | Articles | Comments

All types of scientists are at work, on all kinds of quit-smoking aids, from an anti-smoking vaccine to a biomarker test. Read more...                                         

Europe's First Fully Remote Diabetes Trial Approved

February 11, 2015 9:46 am | News | Comments

This remote clinical study to include full electronic informed consent. Read more...                            

CDK4/6 Inhibitor: Promising Results for Treating Breast Cancer

February 9, 2015 1:06 pm | by Drug Discovery & Development staff | Articles | Comments

The words “exciting,” “breakthrough,” and “standard-of-care-changing” are being used with regard to cyclin-dependent kinase (CDK) 4 and 6 inhibitors and metastatic breast cancer. Read more...                                       

A Look at Some Vaccine-Related Legislation in Several States

February 6, 2015 4:07 pm | by Associated Press | News | Comments

Several state legislatures are debating vaccine-related measures as dozens of people have fallen ill from a measles outbreak that started at Disneyland in December and spread beyond the theme park. Here is a look at some of the legislation around the country. Read more...

The Longevity of Attention Deficit Drugs

February 5, 2015 5:09 pm | by Stephanie Guzowski, Editor | Articles | Comments

Can A.D.H.D. drugs help “normalize“ a child’s brain? Recent research suggests that A.D.H.D. medication may regulate the brain over time, rewiring neural connections, so that the focus and in-control effect endures. Read more...

Needle Biopsies May Be Safe in Pancreatic Cancer

January 29, 2015 4:06 pm | by Cynthia Fox, Science Editor | Articles | Comments

Oncologists and patients who fear tumor needle biopsies—thinking they may cause tumor bits to break off and “seed” cancer elsewhere—may rest easier after reassuring Mayo Clinic news. Read more...                   

New Biological Evidence Reveals Link Between Brain Inflammation, Depression

January 29, 2015 10:46 am | by Centre for Addiction and Mental Health | News | Comments

A new study by the Centre for Addiction and Mental Health (CAMH) found that the measure of brain inflammation in people who were experiencing clinical depression was increased by 30 percent. The findings, published today in JAMA Psychiatry, have important implications for developing new treatments for depression. Read more..

Rotavirus Vaccine Reduces Severe Diarrhea by 64 Percent

January 29, 2015 9:12 am | by University of Liverpool | News | Comments

Researchers have found that diarrhoea caused by rotavirus infection is significantly reduced in the developing world with the use of a vaccine to prevent the condition. Read more...             

Aprea's Ovarian Cancer Drug Gains Orphan Drug Designation

January 23, 2015 3:47 pm | News | Comments

The drug gained this designation in Europe. Read more...                                  

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