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Daily news and top headlines for drug research professionals

Medication Being Studied Could Help Afib Patients After Stroke

December 15, 2014 1:03 pm | by University of South Florida | News | Comments

Researchers are studying the effectiveness of a new rapid-onset anticoagulant medication with the standard anticoagulant drug in stroke patients with atrial fibrillation, the most common type of abnormal heart rhythm. Read more...     

Cancer Patients Testing Drugs on Mouse Avatars

December 15, 2014 12:56 pm | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

The idea is to see which drugs might work best on a specific person's specific cancer. Read more...                           

Tackling One of The Biggest Questions in Dementia Research

December 15, 2014 11:06 am | by University of Southampton | News | Comments

Researchers in Southampton are tackling one of the biggest questions in dementia research; why might current approaches in Alzheimer's trials be failing? The new study is published in the Journal of Pathology and funded by Alzheimer's Research UK and the Medical Research Council. Read more...


Potential Hepatitis B Cure Enters Clinical Trial

December 15, 2014 8:52 am | News | Comments

A new treatment promoting the cure of chronic hepatitis B is now recruiting patients for clinical trials. Read more....                        

Understanding Intestinal Microbiota to Regain Balance in the Gut

December 12, 2014 10:42 am | by Natalie Duggan, Emory | News | Comments

When you take antibiotics, some of the beneficial germs can be wiped out, leaving you more vulnerable to diarrheal infections—infections, in some cases, that are antibiotic resistant and life-threatening. Read more...                                    

TWi Biotechnology Receives FDA Protocols for Gout Drug

December 12, 2014 10:30 am | News | Comments

TWi Biotechnology Inc. has received US FDA and Taiwan FDA approval of a protocol for a Phase 2 clinical trial of gout drug. Read more...                     

Merck Advancing Breast Cancer Drug to Mid-Stage

December 11, 2014 11:33 am | by Linda A. Johnson - AP Business Writer | News | Comments

Merck said it will start mid-stage patient tests of Keytruda in the first half of 2015. Read more...                           

‘Placebo Therapy’ Ineffective For Long-Term Chronic Pain Relief

December 11, 2014 9:13 am | News | Comments

Scientists at the University of Liverpool have shown that ‘placebo therapy’ could be effective for short-term pain relief in patients with Complex Regional Pain Syndrome (CRPS), but does not have a lasting impact. Read more...                              


Prescribed Painkiller Not Effective in Controlling Back Pain

December 10, 2014 4:35 pm | by University of Rochester | News | Comments

A new study out in the journal Neurology shows that pregabalin is not effective in controlling the pain associated with lumbar spinal stenosis, the most common type of chronic lower back pain in older adults. Read more...

Generic Antiepilepsy Drugs Have Minimal Differences: Study

December 10, 2014 12:32 pm | by University of Cincinnati | News | Comments

A comparison of two of the most disparate approved generic antiepileptic drugs found minimal differences when compared under rigorous testing procedures in people with epilepsy, according to research presented by a University of Cincinnati (UC) clinician-researcher. Read more...

Combo Treatment Benefits Women with Metastatic Breast Cancer

December 10, 2014 10:07 am | News | Comments

Results of a Phase 2, open-label, dose-confirmation study of eribulin in combination with capecitabine, suggests that this therapy is efficacious in women with metastatic breast cancer (overall response rate 42.9% and clinical benefit rate 57.1%), with a safety and tolerability profile consistent with previous data. Read more...

Simeprevir-Based Therapy: Cost-Effective HCV Treatment

December 10, 2014 9:44 am | by UPenn | News | Comments

Researchers at Penn Medicine have shown that a protease inhibitor, simeprevir, a once a day pill, along with interferon and ribavirin has proven as effective in treating chronic HCV as telaprevir with interferon and ribavirin, the standard of care in developing countries. Read more...

Parkinson's Vaccine Being Tested on Patients in Europe

December 9, 2014 9:24 am | News | Comments

This vaccine is one out of a designated pool of promising vaccine candidates. Read more...                             


AbbVie Announces Phase 2 Results for AML Treatment

December 8, 2014 3:07 pm | News | Comments

AbbVie presented new results from a Phase 2 study of a treatment for AML at the American Society of Hematology's 56th Annual Meeting. Read more...                   

Tasigna Wins Over Gleevec in Ph+CML Patients

December 8, 2014 1:45 pm | News | Comments

Six-year results from Novartis' randomized Phase 3 study continue to demonstrate the superiority of Tasigna compared to Glivec. Read more...                   

Journal Watch: Tamoxifen in the News Again

December 8, 2014 11:57 am | by Drug Discovery & Development Staff | Articles | Comments

Tamoxifen, the leading estrogen blocker, has done so well by hormone receptor-positive breast cancer patients that the American Society for Clinical Oncology (ASCO) changed its guidelines this year, advising certain patients to take the drug for ten years instead of five. Read more...

Takeda's Amyloidosis Inhibitor Gains Breakthrough Therapy Designation

December 5, 2014 10:13 am | News | Comments

Takeda's amyloidosis inhibitor was designated as a breakthrough therapy by the FDA. Read more...                            

Building Personalized Approaches to Patient Care

December 5, 2014 9:43 am | by Jonathan Sheldon, PhD, global vice president, Oracle Health Sciences | Articles | Comments

With the evolution of electronic medical records (EMR) systems, and the integration of genomic data with multi-dimensional longitudinal clinical data, the opportunity is rife to build truly personalized approaches to patient care. 

Why Some Patients Respond to a Life-Saving Melanoma Drug

December 4, 2014 10:29 am | News | Comments

UCLA researchers have pioneered a new methodology to predict why some patients battling advanced melanoma respond well and others do not to the new breakthrough drug pembrolizumab. The study, led by UCLA Jonsson Comprehensive Cancer Center members Dr. Paul Tumeh and Dr. Antoni Ribas, primary investigator of pembrolizumab. Read more....

PET Scans Help Identify Effective TB Drugs

December 3, 2014 4:41 pm | by University of Pittsburgh | News | Comments

Sophisticated lung imaging can show whether or not a treatment drug is able to clear tuberculosis (TB) lung infection in human and macaque studies, according to researchers at the University of Pittsburgh School of Medicine and their international collaborators. Read more...          

Study: Strengthening Evidence of Connection Between Statin Use, Cataracts

December 3, 2014 12:35 pm | by Elsevier | News | Comments

Few classes of drugs have had such a transformative effect on the prevention of cardiovascular disease (CVD) as have statins, prescribed to reduce total cholesterol and low-density lipoprotein cholesterol. However, some clinicians have ongoing concerns regarding the potential for lens opacities (cataracts) as a result of statin use. Read more...

Predicting Alzheimer’s Disease With Blood Tests: Early Detection, Ethical Concerns

December 2, 2014 9:52 am | by Stephanie Guzowski, Editor | Articles | Comments

If you could take a blood test that could detect — with nearly 100% accuracy — whether you were genetically destined to get Alzheimer’s disease, would you take that test? Read more...

Breast Cancer Vaccine Shows Promise in Small Clinical Trial

December 1, 2014 1:02 pm | by Julia Evangelou Strait, Washington University | News | Comments

A breast cancer vaccine developed at Washington University School of Medicine in St. Louis is safe in patients with metastatic breast cancer, results of an early clinical trial indicate. Preliminary evidence also suggests that the vaccine primed the patients’ immune systems to attack tumor cells and helped slow the cancer’s progression. The study appears in Clinical Cancer Research. Read more...

Imaging Shows Brain Connection Breakdown in Early Alzheimer’s

December 1, 2014 12:45 pm | News | Comments

Changes in brain connections visible on MRI could represent an imaging biomarker of Alzheimer's disease, according to a new study presented at the annual meeting of the Radiological Society of North America (RSNA). Read more...

Abivax Completes First-In-Man Study of HIV Treatment

December 1, 2014 10:55 am | News | Comments

Abivax, a leading clinical stage biotech company developing and commercialising anti-viral compounds and human vaccines, announced the successful completion of its Phase 1 first-in-man study of ABX464, which has been designed to potentially deliver a number of important clinical benefits when treating patients with HIV. Read more...

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