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The Lead

Multi-Million-Dollar Deal Brings UQ Pain Drug Closer to Reality

June 29, 2015 4:00 pm | by University of Queensland | News | Comments

A chronic pain treatment discovered at The University of Queensland is a step closer to clinical use. Read more...

New Study Verifies Accuracy of Rapid Ebola Test

June 29, 2015 3:56 pm | by Tulane University | News | Comments

The study results confirm that the test can be used in the field and deliver a high level of...

Lilly, Immunocore: Immunotherapy-based Clinical Trial Collaboration in Melanoma

June 29, 2015 9:48 am | News | Comments

Eli Lilly and Company and Immunocore Limited today announced that they have entered into an ...

Scientists Look Into Why Most Alzheimer's Patients Are Women

June 29, 2015 9:42 am | by Lauren Neergaard, AP Medical writer - Associated Press | News | Comments

Nearly two-thirds of Americans with Alzheimer's disease are women, and now some scientists are...

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TSRI and Biotech Partners Find New Antibody Weapons against Marburg Virus

June 29, 2015 9:34 am | by The Scripps Research Institute | News | Comments

A new study led by scientists at The Scripps Research Institute (TSRI) identifies new immune molecules that protect against deadly Marburg virus, a relative of Ebola virus. The research provides ingredients needed to develop treatments for future Marburg outbreaks. Read more...

Turning the Tables on Cancer

June 29, 2015 9:29 am | by Shari Roan, UCLA | News | Comments

A new class of immunotherapies is enlisting the body's own immune system to fight cancer. Read more...

Blood Test IDs Pancreatic Cancer in 250 of 250 Patients

June 29, 2015 9:18 am | by Cynthia Fox, Science Editor | Articles | Comments

A new blood test identified pancreatic cancer with 100 percent accuracy in 250 of 250 patients, said a recent report in Nature. The test found pancreatic exosomes in blood via the biomarker GPC1. It distinguished early-stage cancer from late-stage cancer—with zero false positives/negatives. It predicted survival. Read more...

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Major Step for Implantable Drug Delivery Device

June 29, 2015 8:41 am | by MIT | News | Comments

An implantable, microchip-based device may soon replace the injections and pills now needed to treat chronic diseases. Read more...

DNA Damage Linked with Dementia

June 29, 2015 8:29 am | by University of Sheffield | News | Comments

High levels of DNA damage in nerve cells can lead to dementia. Read more...

Drug Discovery Spotlight: ASCO’s Cancer Drugs Rating Scale; Hepatitis C Drug Patent Rejected in China

June 26, 2015 12:59 pm | by Stephanie Guzowski, Editor | News | Comments

The American Society of Clinical Oncology said it would provide a rating scale for cancer drugs, and now it’s delivered — and not all the score results are assuring. Pharma’s next five years look promising, according to an industry report. Read more...

California Vaccine Bill Clears Legislative Hurdle

June 26, 2015 10:43 am | by Seth Augenstein, Digital Reporter | News | Comments

A split California Assembly approved a bill that would require nearly all public school kids to get basic vaccines Thursday. The bill passed on a bipartisan 46 to 30 vote and, if signed by the governor, would give California one of the strictest vaccine requirements, by eliminating the “personal belief” exemption used by anti-vaccine parents. Read more...

Delivering Drugs to the Right Place

June 26, 2015 9:27 am | by UC Santa Barbara | News | Comments

For the 12 million people worldwide who suffer from polycystic kidney disease (PKD), an inherited disorder with no known cure, a new treatment option may be on the horizon. Read more...

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Alzheimer’s Expert Jams with Aerosmith

June 26, 2015 8:59 am | by Bevin Fletcher, Associate Editor | News | Comments

One of the world’s leading Alzheimer’s researchers doubles as a guest organist for Aerosmith. Rudy Tanzi, Ph.D., the Kennedy professor of neuroscience at Harvard, hit it off with lead guitarist Joe Perry on a photo shoot for men’s fashion magazine GQ, and the scientist, who is an expert on how beta amyloid accumulates in the brain, has since played with the band on a number of special occasions, CNN reported. Read more...

Human Trials of Manufactured Blood within Two Years

June 26, 2015 8:34 am | by University of Bristol | News | Comments

The clinical trial of manufactured red blood cells is designed to compare the survival of red cells manufactured from stem cells with that of standard blood donor red blood cells. Read more...

Melatonin Offers Hope for ADHD Bedtime Shut-Eye

June 26, 2015 8:32 am | by University of Queensland | News | Comments

Researchers are recruiting trial participants for a study investigating the effectiveness of the natural hormone melatonin on children with ADHD who are struggling to settle at bedtime. Read more...

Breast Cancer Paper to Be Retracted– 3 Years After False Data Exposed

June 26, 2015 8:31 am | by Seth Augenstein, Digital Reporter | News | Comments

An academic paper that outlined how breast cancer molecules metastasize will be retracted next week, because of falsified data. Read more...

Medical Research Not Addressing Patient, Clinician Priorities

June 25, 2015 12:37 pm | by BioMed Central | News | Comments

Research on treatments for health problems, such as diabetes, stroke and schizophrenia, is not being focused on the treatments considered most important by patients and clinicians, according to a study published in the open access journal Research Involvement and Engagement. Read more...

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Scientists Pinpoint Mutations Responsible for Ineffective 2014-2015 Flu Vaccine

June 25, 2015 12:25 pm | News | Comments

Viruses like influenza have the ability to mutate over time, and given that the flu vaccines administered during the 2014-2015 season were largely ineffective at preventing the spread of the flu, it appears the virus that recently circulated had taken on mutations not accounted for when last year's vaccine was developed. Read more...

Experimental Treatment Sends Deadly Leukemia Into Remission

June 25, 2015 12:09 pm | by University of Virginia Health System | News | Comments

An experimental new treatment approach for a rare, deadly leukemia can send the disease into remission even in patients for whom the standard therapy has failed, buying them more time to have the stem cell transplant that could save their lives, a small pilot study has found. Read more...

NIH Begins Clinical Trial of New Medication for Alcohol Use Disorder

June 25, 2015 12:02 pm | by NIH | News | Comments

A clinical trial investigating a potential treatment for alcohol use disorder (AUD) was announced by the National Institute of Alcohol Abuse and Alcoholism (NIAAA). The study will assess the safety and efficacy of gabapentin enacarbil (HORIZANT) in extended-release tablets for treating moderate to severe AUD. NIAAA is part of the National Institutes of Health. Read more...

NeuroRx: First Human Trial Results Targeting Bipolar Depression, Suicidality

June 25, 2015 11:52 am | News | Comments

NeuroRx, Inc., a clinical phase pharmaceutical company, reports first-in-man efficacy data for a newly-purposed class of drugs targeted towards rapidly reducing symptoms of depression and suicidality in patients with bipolar disorder and maintaining that effect over time. Read more..

Research Shows Possible Way to Prevent Degenerative Eye Condition

June 25, 2015 9:07 am | by University of Oxford | News | Comments

Stargardt disease affects around 1 in 10,000 people and begins in childhood, leading to progressive loss of central vision. Read more...

New Breath Test for Pneumonia

June 25, 2015 8:58 am | by University of Manchester | News | Comments

Researchers from The University of Manchester are part of a team that has identified an important new approach to diagnose infections in critically ill patients rapidly and accurately. Read more...

Pinpointing the Onset of Metastasis

June 25, 2015 8:55 am | by Lindsay Hock, Editor | News | Comments

Within the oncology community, a debate is raging about two controversial topics. The first is overdiagnosis. According to a recent report in The Wall Street Journal, some leading cancer experts say that zealous screening is finding ever-smaller abnormalities that are being labeled cancer or precancer with little or no justification. Read more...

EU Approves Daiichi Sankyo's Lixiana

June 25, 2015 8:52 am | News | Comments

The drug is intended for stroke prevention in nonvalvular atrial fibrillation and for the treatment and prevention of reccurent DVT and PE. Read more...

Future Antibiotics

June 25, 2015 8:45 am | by MIT | News | Comments

The global rise in antibiotic resistance is a growing threat to public health, damaging our ability to fight deadly infections such as tuberculosis. Read more...

Researchers ID Best Source of Stem Cells to Block Diabetic Blindness

June 24, 2015 12:52 pm | by UVA | News | Comments

University of Virginia School of Medicine researchers have taken a significant step forward in their efforts to use stem cells to block vision loss caused by diabetic retinopathy, a condition that affects millions of people with diabetes. Read more...

For Vitiligo Patient, Arthritis Drug Restores Skin Color

June 24, 2015 12:41 pm | by Yale University | News | Comments

A medication for treating rheumatoid arthritis has restored skin color in a patient suffering from vitiligo, according to dermatologists at Yale School of Medicine. The disfiguring condition is best known as the disease that plagued late pop star Michael Jackson. Read more...

Teens Invent Condom that Glows to Show STDs

June 24, 2015 11:12 am | by Seth Augenstein, Digital Reporter | News | Comments

A group of teenage inventors in the United Kingdom has invented a condom that changes colors to warn of STDs, according to multiple reports. Read more..

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