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Proteins May Slow Memory Loss in People with Alzheimer's

May 22, 2015 10:12 am | by Iowa State University | News | Comments

Certain proteins may slow the devastating memory loss caused by Alzheimer’s disease, according to a groundbreaking Iowa State University study. Read more...

Novel Drug Combo Improves Function of Cystic Fibrosis Protein

May 22, 2015 10:07 am | by Johns Hopkins | News | Comments

A novel two-drug combination has the potential to target and restore a defective protein...

1950s Drug is Future Heart Treatment

May 22, 2015 8:46 am | by University of Oxford | News | Comments

Researchers have found a promising future treatment for heart disease, going back to a drug...

Freshly Squeezed Vaccines

May 22, 2015 8:39 am | by MIT | News | Comments

Researchers have shown that they can use a microfluidic cell-squeezing device to introduce...

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Daily news and top headlines for drug research professionals

Shining a New Light on The Immune System

May 22, 2015 8:24 am | by University of St. Andrews | News | Comments

Researchers used a light scattering technique to identify important types of white blood cells. Read more...

Janssen, Achillion Pharmaceuticals Team Up to Fight Hepatitis C

May 22, 2015 8:24 am | News | Comments

A key objective of the collaboration will be to develop a short-duration, highly effective, pan-genotypic, oral regimen for the treatment of HCV. Read more...

Potential New Drug Target for the Treatment of Rheumatoid Arthritis

May 21, 2015 1:40 pm | News | Comments

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints. Read more...

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Injected T Cells from Bone Marrow Treat Multiple Myeloma, Pilot Study Finds

May 21, 2015 1:12 pm | by Stephanie Guzowski, Editor | Articles | Comments

In a first small clinical trial of its kind, researchers harnessed T cells from patients’ own bone marrow to treat multiple myeloma and provide immune protection for up to a year, according to a study published this week in Science Translational Medicine. Read more...

Chemo Before Surgery Benefits Patients with Advanced Ovarian Cancer

May 21, 2015 9:39 am | by Cancer Research UK | News | Comments

550 women with the disease took part in the trial, with 276 given the standard treatment of surgery followed by six cycles of chemotherapy, and 274 had surgery after three cycles of chemotherapy. Read more...

Brain Plaque Forecasts Alzheimer’s Years in Advance, Studies Confirm

May 20, 2015 1:49 pm | by Stephanie Guzowski, Editor | News | Comments

Brain plaques may appear up to 30 years prior to developing Alzheimer’s disease, according to the largest analysis to date of beta amyloid in people’s brains. Findings from two new meta-analyses  also confirm that amyloid screening, by PET scan or cerebral spinal fluid test, can help identify the best participants for clinical trials of Alzheimer’s drugs. Read more...

Promising Malaria and Dengue Vaccines Will Not Defeat Diseases

May 20, 2015 8:54 am | by Christopher J. Pace, Ph.D., GlobalData Managing Analyst, Infectious Diseases | Articles | Comments

Some industry pundits rightfully question the modest protective efficacies of CYD-TDV and RTS,S/AS01. Read more...

Cancer Drugs Approved Quickly but Not to Patient's Benefit

May 20, 2015 8:46 am | by York University | News | Comments

High priced cancer drugs get rushed approvals despite poor trial methodology and little effect on the longevity of patients. Read more...

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Sanofi, Regeneron Announce Positive Phase 2 Data for Asthma Drug

May 20, 2015 8:42 am | News | Comments

Based on discussions with the U.S. Food and Drug Administration (FDA), this Phase 2b study may be considered one of two pivotal efficacy studies required for a potential dupilumab biologics license application (BLA) in asthma. Read more...  

HIV Reservoirs Remain Obstacles to Cure

May 20, 2015 8:41 am | by NIAID | News | Comments

A primary research goal is to find an HIV cure that either clears the virus from an infected person’s body or enables HIV-infected individuals to suppress virus levels and replication to extremely low levels without the need for daily ART. Read more...

Australian Researcher Helps with Ebola Vaccine Trials

May 20, 2015 8:41 am | by Monash University | News | Comments

An Australian researcher has helped identify the kind of human trial that is most effective for testing Ebola vaccines. Read more...

New Alzheimer's Drug to Enter Clinical Trials

May 20, 2015 8:39 am | by Lancaster University | News | Comments

A new drug developed at Lancaster University that may help to prevent the early stages of Alzheimer’s disease is to enter clinical trials. Read more...

E-cigarettes Aren’t Benign, Suggest Recent Studies

May 19, 2015 4:43 pm | by Drug Discovery & Development Staff | News | Comments

A slew of new studies detailed at the 2015 American Thoracic Society International Conference in Denver, Colorado this week are raising concerns about e-cigarettes (electronic cigarettes, or e-cigs). While the new “drug device” studies are generally ongoing, and so unpublished, their cumulative effect was impactful. Read more...

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Abcodia Raises $8M to Launch Ovarian Cancer Screening Test

May 19, 2015 1:14 pm | by Ryan Bushey, Associate Editor | Articles | Comments

The test will officially be on the market in the U.S. and U.K. later this year. Read more...

Key Component in Protein that Causes Cystic Fibrosis Identified

May 19, 2015 12:31 pm | by University of Missouri | News | Comments

Nearly 70,000 people worldwide are living with cystic fibrosis, a life-threatening genetic disease. There currently is no cure for the condition, but researchers from the University of Missouri have identified a key component in the protein that causes the disease. It is a finding that may lay the foundation for the development of new medications and improved therapies. Read more...

83% of Parents Want Teens Vaccinated against Meningococcal Disease: U.S. Poll

May 19, 2015 12:21 pm | News | Comments

GlaxoSmithKline today announced the results of an online consumer poll, conducted by Harris Poll on behalf of GSK, of US parents with children ages 16 to 21 years, and young people of the same age range, gauging the knowledge of and attitudes related to meningococcal disease. Read more...

Multiple Sclerosis: Scientists ID Cause of Movement, Balance Problems

May 19, 2015 12:05 pm | by University of Virginia Health System | News | Comments

New research into the causes of the excessive inflammation that drives multiple sclerosis has identified a faulty “brake” within immune cells, a brake that should be controlling the inflammation. Read more...

Inner-City Asthma Care Program Reduces Student Absenteeism by Up to 20 Percent, Shows Study

May 19, 2015 12:00 pm | News | Comments

New data from a school asthma management program, “Building Bridges for Asthma Care,” presented today at the American Thoracic Society 2015 International Conference, show a significant decrease in school absenteeism among children with asthma from inner-city schools who were enrolled in the program. Read more...

Roche Gains FDA CLIA Waiver for Strep A Test

May 19, 2015 8:39 am | News | Comments

CLIA waiver allows for broad use of the test by healthcare providers in non-traditional laboratory sites, including physician offices, emergency rooms, health department clinics, pharmacy clinics and other healthcare facilities. Read more...

Scientists Announce Major Breakthrough Against Rare Kidney Disease

May 19, 2015 8:32 am | by University of Manchester | News | Comments

Scientists have made a significant breakthrough in the fight against Membranous Nephropathy. Read more...

Inflammation Stops The Biological Clock

May 19, 2015 8:27 am | by Trinity College Dublin | News | Comments

Researchers have uncovered an important link between our body clock and the immune system that will have relevance to the treatment of inflammatory and infectious diseases. Read more...

Microchip Captures Circulating Tumor Clusters, Providing Clue to Cancer’s Spread

May 18, 2015 12:02 pm | by Seth Augenstein, Digital Reporter | News | Comments

A tiny microfluidic chip can capture circulating clusters of tumor cells, researchers said. The find could provide important new clues about how cancer spreads – and could even be a “breakthrough technology,” they said. Read more....

Groundbreaking Treatment for Patients with Cystic Fibrosis

May 18, 2015 11:15 am | by Lurie Children's Cystic Fibrosis Center | News | Comments

Treatment with two medications that target the most common genetic cause of cystic fibrosis improves lung function and lowers the rate of pulmonary exacerbations, according to the results from a Phase 3 international clinical trial published online in the New England Journal of Medicine. Read more...

Curing Hepatitis C Could Yield Huge Economic Benefit

May 18, 2015 11:07 am | News | Comments

While a new generation of safer, more effective oral medications to treat hepatitis C patients may cost tens of thousands of dollars for a 12-week regiment, investing in these new therapies could generate savings estimated at more than $3.2 billion annually in the U.S. and five European countries, according to a new study (abstract 228) released at Digestive Disease Week (DDW) 2015. Read more...

Anemia Distorts Regular Method of Diabetes Diagnosis

May 18, 2015 9:23 am | by University of Nottingham | News | Comments

Scientists have found that the blood condition anemia can lead to a false diagnosis of diabetes. Read more...

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