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Neurotrope: Last Patient Dosed in Phase 2a Alzheimer's Study

November 21, 2014 11:41 am | News | Comments

Neurotrope, Inc. announced that the last patient has been dosed in its Phase 2a clinical trial of Bryostatin-1 for the treatment of patients with Alzheimer's disease (AD). The trial is being conducted under an Investigational New Drug (IND) application filed by the Company's licensor, the Blanchette Rockefeller Neuroscience Institute (BRNI). Read more...

Researcher Who Found Cause of Lyme Disease Dies

November 21, 2014 11:32 am | by Associated Press | News | Comments

The Swiss-born...

Powerful Method to Speed Cancer Drug Discovery

November 21, 2014 11:22 am | by Salk Institute | News | Comments

For decades,...

UK Investment to Develop Lung Cancer Drugs

November 21, 2014 9:58 am | News | Comments

A new collaboration in the UK will develop a promising class of cancer inhibitors. Read more......

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Pre-Empting Flu Evolution May Make Better Vaccines

November 21, 2014 9:37 am | News | Comments

An international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by ‘pre-empting’ the evolution of the influenza virus. Read more...           

Breakthrough Found to Help Manage Yellow Fever

November 21, 2014 9:24 am | News | Comments

Yellow fever is a disease that can result in symptoms ranging from fever to severe liver damage. Read more...                         

Beta-Blockers Show No Survival Benefits After Heart Attack

November 21, 2014 8:48 am | by Drug Discovery & Development Staff | Articles | Comments

Beta blockers offer no survival advantages to patients, post-heart attack, but they do improve survival among some heart failure patients. Read more...                                                          

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New Approach for Treating ALS

November 20, 2014 1:45 pm | News | Comments

Researchers show that the brain’s machinery for pumping out toxins is ratcheted up in ALS patients. Read more...                         

Global Obesity Costs Hits $2 Trillion

November 20, 2014 12:35 pm | by Danica Kirka - Associated Press | News | Comments

The global cost of obesity has risen to to nearly as much as smoking or the combined aspect of armed violence, war and terrorism. Read more...                    

Virus Discovery Could Impact HIV Drug Research

November 20, 2014 12:23 pm | News | Comments

A research team has unlocked the structure of an unusual virus that lives in volcanic hot springs. Read more...                         

Promising One-Two Punch for Lung Cancer

November 20, 2014 10:19 am | News | Comments

Scientists at the Salk Institute have discovered a powerful one-two punch for countering a common genetic mutation that often leads to drug-resistant cancers. The dual-drug therapy–with analogs already in use for other diseases–doubled the survival rate of mice with lung cancer and halted cancer in pancreatic cells. Read more...

Early Statin Use May Give Long-Term Heart Benefits

November 20, 2014 10:06 am | by Marilynn Marchione, AP Chief Medical Writer - Associated Press | News | Comments

Taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward, and the benefits seem to grow over time, a landmark study finds. Doctors say it's the first evidence that early use of a statin can have a legacy effect, perhaps changing someone's odds of disease for good. Read more...

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Mental Health Problems Increase Heart Disease Risk

November 20, 2014 9:42 am | by Cynthia Fox, Science Editor | Articles | Comments

People with mental health problems are “significantly” more likely to have stroke or heart disease, according to a study unveiled at a recent Canadian Cardiovascular Congress. Read more...

Bacterial Infections Suppress Immune Response in Neurodermatitis

November 20, 2014 9:31 am | by Technische Universität München | News | Comments

The skin condition neurodermatitis affects nearly one in four children and also occurs frequently in adults. Many patients also develop infections in the dry, open patches of skin, for example due to colonization by the pathogenic bacterium Staphylococcus aureus, which is particularly abundant on the skin of neurodermatitis patients. Read more...

WHO: Ebola Transmission 'Intense' in Sierra Leone

November 20, 2014 9:24 am | by Clarence Roy-Macaulay - Associated Press | News | Comments

The spread of Ebola remains "intense" in most of Sierra Leone even as things have improved somewhat in the two other countries hardest hit, the World Health Organization says. Read more...                             

Maximizing the Power of Preclinical Cancer Research Tools

November 19, 2014 11:29 am | by Guizhong Liu, Senior Director of Cancer Biology, Crown Bioscience Inc. | Articles | Comments

Drug discovery is a protracted and uncertain process that needs to overcome many hurdles during preclinical and clinical development before it finally achieves regulatory approval for patient treatment. For every drug that reaches the marketplace, well over 100 have been abandoned at some point in their development. Read more...

Cardiome Finds Distributor for AFib Drug in South Africa

November 19, 2014 9:59 am | News | Comments

Cardiome entered into a new partnership with Pharmacare Ltd to sell and distribute its AFib drug in South Africa. Read more...                     

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New Laser Therapy Helps Slow Macular Degeneration

November 19, 2014 9:36 am | News | Comments

This new faster laser did not result in damage to the retina. Read more...                               

Study Will Test Survivors' Blood to Treat Ebola

November 19, 2014 9:19 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Plasma from survivors contains antibodies, substances the immune system makes to fight the virus. Read more...                         

New Insight Into Cells Could Lead to Better Drugs

November 19, 2014 9:11 am | News | Comments

Researchers investigated how different types of immune cells communicate with each other – and how they kill cancerous or infected cells. Read more...                   

Reprogramming Cells, Long Term

November 18, 2014 2:07 pm | by B. D. Colen, Harvard Staff Writer | News | Comments

Harvard Stem Cell Institute (HSCI) researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology (MIT), have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period. Read more...

Anti-Leukemia Drug May Also Work Against Ovarian Cancer

November 18, 2014 1:50 pm | News | Comments

An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine in a study. Read more...

Society for Neuroscience Annual Meeting Showcases Strides in Exploring the Brain

November 18, 2014 10:56 am | by Christina Jakubowski, Managing Editor, Bioscience Technology | Articles | Comments

More than 30,000 brain advocates from academia, industry and media converged on Washington, D.C. this week for the 44th annual meeting of the Society for Neuroscience (SfN). Read more...

Weak Spots in Ebola's Defenses

November 18, 2014 10:26 am | by Scripps Institute | News | Comments

Scientists at The Scripps Research Institute (TSRI) have identified weak spots on the surface of Ebola virus that are targeted by the antibodies in ZMapp, the experimental drug cocktail administered to several patients during the recent Ebola outbreak. Read more...

Roche Announces FDA Approval of Ovarian Cancer Treatment

November 17, 2014 1:30 pm | News | Comments

The FDA approves Roche's ovarian cancer treatment. Read more...                                 

Method Developed for Detecting Tumor-Causing Mutations in Saliva

November 17, 2014 1:18 pm | News | Comments

Current methods to screen for lung cancer mutations in plasma or blood are complicated, technique-dependent and not readily available. Read more...                   

Statins Reverse Learning Disabilities Caused By Genetic Disorder

November 17, 2014 1:08 pm | News | Comments

Scientists have discovered that statins reverse the learning disabilities caused by a genetic disorder. Read more...                        

Genzyme's MS Drug Gains FDA Approval

November 17, 2014 12:56 pm | News | Comments

The FDA approved Genzyme's new drug for the treatment of multiple sclerosis. Read more...                             

Study Lifts Cloud Over Heart Drugs

November 17, 2014 12:25 pm | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

A major study lifts a cloud around blockbuster drugs for lowering cholesterol. Read more...                             

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