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Isis Initiates Phase 3 Study of FCS Drug

August 29, 2014 2:00 pm | News | Comments

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 3 study evaluating ISIS-APOCIIIRx in patients with familial chylomicronemia syndrome (FCS). FCS is a rare orphan disease, characterized by extremely high triglyceride levels, that affects an estimated 3,000 to 5,000 patients worldwide. Read more...

Drug-Delivery Vehicle Could Limit Spread of HIV, AIDS

August 29, 2014 2:00 pm | News | Comments

A unique method for delivering compounds that could positively impact the global battle against...

GSK-NIH Ebola Vaccine to Enter Safety Testing

August 28, 2014 2:00 pm | by Seth Borenstein, AP Science Writer | News | Comments

Federal researchers next week will start testing humans with an experimental vaccine to prevent...

New Drug Ups OS in Stage III Colon Cancer

August 28, 2014 2:00 pm | News | Comments

A subset of patients with Stage III colon cancer had improved survival rates when treated with...

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GSK-NIH Ebola Vaccine to Enter Safety Testing

August 28, 2014 2:00 pm | by Seth Borenstein, AP Science Writer | News | Comments

Federal researchers next week will start testing humans with an experimental vaccine to prevent the deadly Ebola virus. The NIH announced today that it is launching the safety trial on a vaccine developed by the agency's National Institute of Allergy and Infectious Diseases and GSK. Read more...

Compound Promises Relief for Inflammatory Pain

August 28, 2014 2:00 pm | News | Comments

Researchers have discovered that a compound they developed could potentially serve as a painkiller, with particular utility for East Asians with an alcohol-metabolizing enzyme mutation. Read more...                

Researchers Investigating New MS Treatment

August 28, 2014 2:00 pm | News | Comments

A new treatment under investigation for multiple sclerosis (MS) is safe and tolerable in Phase 1 clinical trials, according to a new study. The Phase 1 studies were the first to test the drug candidate in humans. Read more...     

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Two-Drug Combo Speeds Wound Healing, Reduces Scar Tissue

August 28, 2014 9:53 am | News | Comments

A combination of two drugs already approved by the U.S. Food and Drug Administration for different applications reduces wound healing time by one-quarter and significantly decreases scar tissue in mice and rats, researchers report. Read more...     

UN: Ebola Cases Could Reach 20,000

August 28, 2014 9:34 am | by John Heilprin and Krista Larson | News | Comments

The Ebola outbreak in West Africa eventually could exceed 20,000 cases, more than six times as many as are now known, the World Health Organization said Thursday. Read more...                      

Marijuana Compound May Slow, Halt Alzheimer’s

August 27, 2014 3:00 pm | News | Comments

Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer’s disease, a new study says. Read more...                   

Potential Therapy for Sudan Ebola Strain May Contain Future Outbreaks

August 27, 2014 2:45 pm | News | Comments

Ebola is a rare, but deadly disease that exists as five strains, none of which have approved therapies. One of the most lethal strains is the Sudan ebolavirus (SUDV). In a new study, researchers report a possible therapy that could someday help treat patients infected with SUDV. Read more...

Compound Suppresses Binge Eating in Mice

August 27, 2014 2:26 pm | News | Comments

Researchers found that the hormone estrogen can specifically trigger brain serotonin neurons to inhibit binge eating, which affects about 5 to 10 percent of U.S. adults, in female mice. Read more...               

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Drug Promising as Potential Anemia Treatment

August 27, 2014 2:21 pm | News | Comments

An experimental drug designed to help regulate the blood’s iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment. Read more...         

Targeted Neuroblastoma Therapy One Step Closer

August 27, 2014 10:52 am | News | Comments

Researchers have uncovered new targets for therapy in the childhood cancer neuroblastoma, bringing hope for the development of novel treatments. Read more...                           

3rd Doctor Dies from Ebola in Sierra Leone

August 27, 2014 10:27 am | by Clarence Roy-Macaulay | News | Comments

A third top doctor has died from Ebola in Sierra Leone, a government official said Wednesday, as health workers tried to determine how a fourth scientist also contracted the disease before being evacuated to Europe. Read more...       

New Statin Guidelines are an Improvement, Study Shows

August 26, 2014 3:18 pm | News | Comments

New national guidelines can improve the way statin drugs are prescribed to patients at risk for cardiovascular disease, a study has found. Read more...                             

Alkermes Launches Phase 1 Pain Treatment Study

August 26, 2014 3:08 pm | News | Comments

Alkermes plc announced the initiation of a Phase 1 clinical study of ALKS 7106, a proprietary, novel, oral, small-molecule drug candidate for the treatment of pain. Read more...                       

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Kite Pharma's Lymphoma Drug Excels in Trial

August 26, 2014 3:03 pm | News | Comments

Shares of Kite Pharma surged before markets opened Tuesday after the drug developer detailed promising results for its most advanced product, a potential treatment for an aggressive form of non-Hodgkin's lymphoma. Read more...       

Pfizer, Merck to Explore Novel Anti-Cancer Combo

August 26, 2014 2:55 pm | News | Comments

Pfizer Inc. and Merck & Co. Inc. announced that they have entered into an agreement to explore the therapeutic potential of the combination of Pfizer’s crizotinib with Merck’s investigational anti-PD-1 antibody pembrolizumab. Read more...   

Cancer-Fighting Drugs Might Also Stop Malaria Early

August 26, 2014 2:47 pm | News | Comments

Scientists searching for new drugs to fight malaria have identified a number of compounds- some of which are currently in clinical trials to treat cancer- that could add to the anti-malarial arsenal. Read more...            

Drug Cured 16 of 16 Monkeys with Viral Ebola Relative

August 26, 2014 11:31 am | by Cynthia Fox, Science Editor | Articles | Comments

An experimental drug saved the lives of 16 of 16 monkeys with the Marburg virus, a killer near-indistinguishable from Ebola, just as symptoms broke out, said a new study. Read more...                   

New Ebola Vaccine Study Delivers Promising Results

August 26, 2014 10:44 am | News | Comments

Immunovaccine Inc. announced positive results for a vaccine formulated in its DepoVax technology in an Ebola virus challenge study performed by the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH). Read more...

Protein Family Can Inhibit HIV Release

August 26, 2014 10:30 am | News | Comments

A family of proteins that promotes virus entry into cells also has the ability to block the release of HIV and other viruses, researchers have found. Read more...                         

Avanir Launches Phase 2 MDD Drug Study

August 26, 2014 10:23 am | News | Comments

Avanir Pharmaceuticals Inc. announced the enrollment of the first patient into a Phase 2 study to evaluate the efficacy, safety and tolerability of AVP-786 for the adjunctive treatment of major depressive disorder (MDD). Read more...     

US Health Official: Ebola Has 'Upper Hand'

August 26, 2014 10:14 am | by Jonathan Paye-Layleh | News | Comments

The Ebola virus has the "upper hand" in an outbreak that has killed more than 1,400 people in West Africa, a top American health official said, adding that experts have the tools to stop it. Read more...             

U.S. Army Funds PTSD Treatment Trial

August 25, 2014 3:16 pm | News | Comments

NeuroSigma Inc. announced that the U.S. Department of the Army has funded a Phase 2 clinical trial at UCLA that will examine the use of external trigeminal nerve stimulation (eTNS) as treatment for PTSD. Read more...          

DNA Repair Drug Could Help Treat Leukemia, Other Cancers

August 25, 2014 10:19 am | News | Comments

A team of scientists found that a drug originally designed for killing a limited type of cancer cells with DNA repair defects could potentially be used to treat leukemia and other cancers. Read more...              

Japan Ready to Offer Flu Drug for Ebola Treatment

August 25, 2014 9:54 am | by Mari Yamaguchi | News | Comments

Japan said Monday it is ready to provide a Japanese-developed anti-influenza drug as a possible treatment for the rapidly expanding Ebola outbreak. Read more...                         

Baxter's Hemophilia Drug Hits Phase 3 Endpoint

August 22, 2014 4:05 pm | News | Comments

Baxter International Inc. announced positive results from its Phase 3 pivotal clinical trial of BAX 855, an investigational, extended half-life recombinant factor VIII (rFVIII) treatment for hemophilia A. Read more...          

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