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Investigational Therapy Could Attack Cause of Sickle Cell Crises

March 3, 2015 11:47 am | News | Comments

Treatment for painful episodes of blood vessel obstruction in sickle cell anemia is currently limited to controlling pain, but an investigational therapy might be able to interfere with the underlying cause of these events, known as vaso-occlusion crises, researchers at Duke Medicine report. Read more...

FDA Grants Orphan Drug Designation to Oncolytics' Cancer Treatment

March 3, 2015 9:03 am | News | Comments

Oncolytics has supported two sponsored clinical studies assessing reolysin in the treatment of...

Amgen Announces Results of Phase 3 Head-to-Head Study of Drugs for Multiple Myeloma

March 2, 2015 12:59 pm | News | Comments

Patients receiving one of the medications that was tested lived twice as long without disease...

Quick Antibiotics Reduce PICU Needs, Mortality of Pediatric Cancer Patients

February 26, 2015 11:18 am | News | Comments

A University of Colorado Cancer Center study published in the journal Pediatric Blood &...

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Graphene Shows Potential as Novel Anti-Cancer Therapeutic Strategy

February 26, 2015 8:35 am | by University of Manchester | News | Comments

Scientists have used graphene to target and neutralize cancer stem cells while not harming other cells. Read more...                         

New Polio Vaccine Gets Funding for Development, Trail

February 25, 2015 10:29 am | by Georgia Institute of Technology | News | Comments

The Georgia Institute of Technology and Micron Biomedical have been awarded $2.5 million in grants from the Bill & Melinda Gates Foundation to advance the development of dissolvable microneedle patches for polio immunization. Read more...

Small Molecule May Help Reduce Cancer in At-Risk Population

February 25, 2015 9:51 am | by Kimberless D'Ardenne, Stanford University | News | Comments

Scientists have shown that small molecules can “hijack” enzyme function in mice, suggesting a possible preventive mechanism for alcohol-related cancers in an at-risk population. Read more...

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FDA Approves Novartis' HDAC Inhibitor for Multiple Myeloma

February 24, 2015 3:23 pm | News | Comments

This inhibitor is the first of its kind for multiple myeloma. Read more...                               

Scientists Find Cancer Weak Spots for New Targeted Drugs

February 24, 2015 3:15 pm | by University of Sussex | News | Comments

Scientists have identified weak spots in cancer cells that could be targeted and attacked by new precision drugs. Read more...                      

Worldwide Treatment of Hepatitis C: Within Sight At Right Cost?

February 23, 2015 4:37 pm | by University of Liverpool | News | Comments

Lowering the cost of hepatitis C drugs is possible and key to achieving global access to treatment, according to new research by the University of Liverpool and Imperial College London. Read more...

Evaluating Drugs to Improve Vision In Diabetic Macular Edema

February 20, 2015 12:05 pm | by Marla Paul, Northwestern Univ. | News | Comments

A national study led by Northwestern Medicine shows the drug Eylea is superior for improving the eyesight of persons with poor vision due to diabetic macular edema, a major cause of vision loss from diabetes, according to Lee Jampol, MD, Louis Feinberg, MD, Professor of Ophthalmology. Read more...

Researchers Discover Potential Treatment for Drug Resistant TB

February 20, 2015 8:59 am | by University of Georgia | News | Comments

This form of the disease cannot be cured with conventional therapies. Read more...                             

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The Journey to an HIV Vaccine Endures

February 19, 2015 12:46 pm | by Stephanie Guzowski, Editor | Articles | Comments

Despite more than 30 years of efforts, scientists have not yet come up with a reliably effective HIV vaccine — in part, because of the inherently complicated nature of the virus. Here are where their research efforts stand today.

Development of Personalized Cellular Therapy for Brain Cancer

February 19, 2015 9:55 am | by UPenn | News | Comments

Immune cells engineered to seek out and attack a type of deadly brain cancer were found to be both safe and effective at controlling tumor growth in mice that were treated with these modified cells, according to a study published in Science Translational Medicine by a team from the Perelman School of Medicine at the University of Pennsylvania and the Novartis Institutes for BioMedical Research. Read more...

Study Highlights Drug Targets for Allergies, Asthma

February 18, 2015 2:56 pm | by Sam Wong, Imperial College London | News | Comments

The new findings could lead to new treatments for allergic diseases, and will help to predict who will best respond to currently available treatments. Read more...                

Scientists Announce Anti-HIV Agent So Powerful It Can Work in a Vaccine

February 18, 2015 2:34 pm | by Scripps Research Institute | News | Comments

Scientists have announced the creation of a novel drug candidate that is so potent and universally effective, it might work as part of an unconventional vaccine. Read more...              

New Drug Target for Multiple Sclerosis Discovered

February 18, 2015 8:59 am | by Centre for Addiction and Mental Health | News | Comments

Scientists have discovered a promising new approach to treat multiple sclerosis. Read more...                            

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Link Between Genetic Switch, Autoimmune Diseases

February 17, 2015 12:53 pm | by NIH | News | Comments

Investigators with the National Institutes of Health have discovered the genomic switches of a blood cell key to regulating the human immune system. The findings, published in Nature, open the door to new research and development in drugs and personalized medicine to help those with autoimmune disorders such as inflammatory bowel disease or rheumatoid arthritis. Read more...

Ovarian Cancer Target Could Mean Earlier Detection, Treatments

February 17, 2015 12:32 pm | by The Wistar Institute | News | Comments

Researchers at The Wistar Institute have made an exciting discovery in a form of ovarian cancer, often considered one of the most difficult-to-treat forms of cancer. In a new study published in the journal Nature Medicine, this potential target could lead to both biomarkers for earlier detection of the disease as well as serve as a basis for new targeted therapies.

Marvel Molecule Could Lead to Inflammatory Disease Treatments

February 17, 2015 10:13 am | by Trinity College Dublin | News | Comments

Scientists from Trinity College Dublin believe that the marvel molecule — MCC950 — could one day be used to treat a myriad of these diseases. Read more...

Scientists Limit Accelerated Cellular Aging Caused by Methamphetamine Use

February 13, 2015 10:41 am | by UC Irvine | News | Comments

The ravaged faces of methamphetamine addicts tell a terrible tale – abusing the drug dramatically accelerates aging. Read more...                      

Computer Model of Blood Development Could Speed Up Search for New Leukemia Drugs

February 11, 2015 9:13 am | by University of Cambridge | News | Comments

 The human body produces over 2.5 million new blood cells during every second of our adult lives, but how this process is controlled remains poorly understood. Read more...              

Roche Acquires Signature Diagnostics to Enhance Genomic Research Efforts

February 10, 2015 12:19 pm | News | Comments

The amount of money paid for Roche's new acquisition is unknown. Read more...                               

Could There Be a Gleevec for Brain Cancer?

February 10, 2015 12:06 pm | by Columbia University | News | Comments

The drug was specifically designed to target an abnormal molecule—a fusion of two normal cell proteins—that fueled a tumor’s growth. Read more...                   

Study Shows Why Some Targeted Cancer Drugs Lose Effectiveness

February 10, 2015 11:53 am | by Pete Farley, UCSF | News | Comments

A protein plays a key role in the emergence of resistance to targeted cancer therapies. Read more..                            

Evaluating Strategies for HIV Vaccinations

February 6, 2015 4:03 pm | by Anne Trafton, MIT | News | Comments

Through an investigation of a fundamental process that guides the maturation of immune cells, researchers have revealed new insights into possible ways to vaccinate people to generate potent antibodies of the type that are predicted to offer protection against diverse strains of the highly mutable HIV. Read more...

Nanocarrier Drugs for Pancreatic Cancer Now Produced In China

February 6, 2015 1:59 pm | by Tianjin Medical University Cancer Hospital | News | Comments

At the "Symposium on the Application of Genetic Testing in Individualized Diagnosis and Treatment of Tumor" recently held in Tianjin, the research team led by Professor Hao Jihui of the Pancreas Oncology Department of Tianjin Medical University Cancer Hospital announced that they had achieved a major breakthrough in the field of nano-carrier drugs for pancreatic cancer.  Read more...

Reversing the Global Diabesity Epidemic

February 6, 2015 1:42 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Articles | Comments

Diabesity has been identified as a major global health problem by researchers and healthcare professionals world-wide, including England’s National Health Service, Brigham and Women’s Hospital and Harvard Medical School, Ain Shams University Hospital in Cairo, Egypt, and a research consortium of the European Union. Read more...

Diamonds Could Help Bring Proteins into Focus

February 6, 2015 8:56 am | by David L. Chandler - MIT | News | Comments

A new technique shows great promise for producing highly detailed images of individual proteins. Read more...                         

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