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Hypertension Medication that Targets Stress May Help Smokers Quit

December 18, 2014 11:23 am | by Daniel Jones, Yale University | News | Comments

Smokers trying to quit often light up a cigarette to deal with stress. Now an interdisciplinary team of Yale researchers has shown that guanfacine, a medication approved for treating hypertension that reduces stress and enhances cognition, shows promise as a smoking cessation aid. Read more...

Microcapsule Eliminates Toxic Punch of Experimental Anti-Cancer Drug

December 18, 2014 11:15 am | by Johns Hopkins | News | Comments

Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates...

Enamine, Sanofi Extend Early Drug Discovery Collaboration

December 18, 2014 9:06 am | News | Comments

Enamine and Sanofi extend partnership for early drug discovery. Read more...   ...

Study: Removing Clot Helps Limit Stroke Disability

December 17, 2014 2:25 pm | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

A new treatment has been shown to limit the damage from a common type of stroke. Read more...

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Predicting Antibiotic Resistance

December 17, 2014 10:14 am | News | Comments

Treating bacterial infections with antibiotics is becoming increasingly difficult as bacteria develop resistance to the antibiotics being used against them. Read more...                

Women in Cell Biology Award Winners Announced at ASCB Meeting

December 15, 2014 4:47 pm | by Stephanie Guzowski, Editor | Articles | Comments

Three exceptional women were given awards for their achievements and contributions to the scientific community at the 2014 ASCB (American Society for Cell Biology) meeting recently held in Philadelphia, Pa. Read more...                               

Study Shows Potential for Faster Drug Development

December 15, 2014 1:47 pm | News | Comments

A new study demonstrates the ability to conduct robust cardiac safety characterizations several years earlier than current practice. Read more...                    


Scientists Reveal Neurotransmitter Binding-Site Function

December 15, 2014 1:15 pm | by Ellen Goldbaum, University of Buffalo | News | Comments

New research from University at Buffalo scientists will help pharmacologists better understand how drugs work and how to make them more effective. Read more...                 

Medication Being Studied Could Help Afib Patients After Stroke

December 15, 2014 1:03 pm | by University of South Florida | News | Comments

Researchers are studying the effectiveness of a new rapid-onset anticoagulant medication with the standard anticoagulant drug in stroke patients with atrial fibrillation, the most common type of abnormal heart rhythm. Read more...     

Potential Hepatitis B Cure Enters Clinical Trial

December 15, 2014 8:52 am | News | Comments

A new treatment promoting the cure of chronic hepatitis B is now recruiting patients for clinical trials. Read more....                        

Taming Inflammatory Response in Kidney Dialysis

December 12, 2014 11:02 am | News | Comments

Over the past several years, lead author John Lambris, PhD, the Dr. Ralph and Sallie Weaver Professor of Research Medicine, Perelman School of Medicine at the University of  Pennsylvania, and his colleagues have developed small molecule versions of the drug compstatin, which inhibits a component of the complement immune response called C3. Read more...

Team Discovers Reasons for Malaria's Drug Resistance

December 12, 2014 9:38 am | by Nanyang Technological University | News | Comments

Scientists have discovered exactly how the malaria parasite is developing resistance towards the most important front-line drugs used to treat the disease. Read more...                


Supporting Drug Development Process with Raman Spectroscopy

December 11, 2014 11:25 am | by Kathleen A. Martin, Ph.D., Senior Research Chemist, McCrone Associates, Inc. | Articles | Comments

Raman spectroscopy has steadily gained a wider role in the pharmaceutical industry because of its applicability to several important aspects of drug development and manufacturing. Read more...                         

Simeprevir-Based Therapy: Cost-Effective HCV Treatment

December 10, 2014 9:44 am | by UPenn | News | Comments

Researchers at Penn Medicine have shown that a protease inhibitor, simeprevir, a once a day pill, along with interferon and ribavirin has proven as effective in treating chronic HCV as telaprevir with interferon and ribavirin, the standard of care in developing countries. Read more...

Drug Target Discovery May Improve Schizophrenia Treatment

December 10, 2014 9:18 am | News | Comments

Scientists have identified a novel drug target that could lead to the development of better antipsychotic medications. Read more...                      

Laughing Gas Studied as Depression Treatment

December 9, 2014 3:22 pm | by Jim Dryden, Washington University in St. Louis | News | Comments

Nitrous Oxide has shown early promise as a potential treatment for severe depression in patients whose symptoms don’t respond to standard therapies. Read more...                 

Startup Aims to Develop 100 Drugs in 10 Years

December 9, 2014 12:59 pm | by University of Utah | News | Comments

A start-up wants to quickly and affordably identify unexpected ways a drug could be used by testing it on diseased cells. Read more...                     


New Agent Shrinks Small Cell Lung Tumors in Pre-Clinical Testing

December 8, 2014 1:20 pm | News | Comments

Researchers found that a new agent can disable the basic part of a tumor cell's survival mechanism. Read more...                         

New Immunotherapy Breakthrough Discovered

December 8, 2014 1:06 pm | by Robert Levy, Harvard Medical School | News | Comments

A therapy that liberates the immune system to attack cancer cells drove Hodgkin lymphoma into complete or partial remission. Read more...                     

Breakthrough in Fibrosis Research

December 8, 2014 10:33 am | by University of Bath, UK | News | Comments

Researchers from the Departments of Pharmacy & Pharmacology and Biology & Biochemistry have made an important discovery that might lead to novel therapies to combat chronic fibrotic diseases. Read more...                          

Resistance and Futility

December 5, 2014 12:25 pm | by Elizabeth Cooney, Harvard Medical School | News | Comments

New findings reveal how penicillin deals bacteria a devastating blow. Read more...                              

Building Personalized Approaches to Patient Care

December 5, 2014 9:43 am | by Jonathan Sheldon, PhD, global vice president, Oracle Health Sciences | Articles | Comments

With the evolution of electronic medical records (EMR) systems, and the integration of genomic data with multi-dimensional longitudinal clinical data, the opportunity is rife to build truly personalized approaches to patient care. 

Why Some Patients Respond to a Life-Saving Melanoma Drug

December 4, 2014 10:29 am | News | Comments

UCLA researchers have pioneered a new methodology to predict why some patients battling advanced melanoma respond well and others do not to the new breakthrough drug pembrolizumab. The study, led by UCLA Jonsson Comprehensive Cancer Center members Dr. Paul Tumeh and Dr. Antoni Ribas, primary investigator of pembrolizumab. Read more....

Scientists Describe New Herpes Treatment Strategy

December 3, 2014 4:49 pm | News | Comments

Scientists have developed a novel treatment approach for persistent viral infections such as herpes. Read more...                                                     

Researchers Study Alzheimer's Investigational Drug

December 3, 2014 12:13 pm | by University of Cincinnati | News | Comments

Researchers at the University of Cincinnati (UC) are among those who have accepted the challenge of easing the burden of Alzheimer’s disease. They are conducting a research study to assess the effect of a new investigational drug on memory and activities of daily living in people with mild to moderate Alzheimer’s. Read more...

World-First Aspirin Study Reaches New Milestone

December 3, 2014 10:07 am | by Monash University | News | Comments

Australia’s largest clinical trial is a step closer to revealing in 2018 whether healthy older people should or should not take aspirin to prevent or delay certain diseases. Read more...             

Study Links Vitamin D Deficiency With Depression

December 3, 2014 9:57 am | by University of Georgia | News | Comments

University of Georgia led an international study that discovered depression was linked with a vitamin D deficiency. Read more...                      

Tailor-Made Pharmaceuticals As Basis for Novel Antidepressants

December 2, 2014 12:42 pm | by Max Planck Institute | News | Comments

Scientists at the Max Planck Institute of Psychiatry in Munich have now developed the first potent and highly selective inhibitor for stress-related psychiatric disorders. Read more...             

Vaccines May Make War on Cancer Personal

December 2, 2014 12:18 pm | by Michael C. Purdy, Washington University in St. Louis | News | Comments

Physicians may treat some cancer patients with personalized vaccines that spur their immune systems to attack malignant tumors. Read more...                    

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