Advertisement
Drug Discovery
Subscribe to Drug Discovery

The Lead

AstraZeneca, Illumina Partner on Gene Sequencing

August 21, 2014 4:12 pm | News | Comments

AstraZeneca announced that it has entered into a collaboration with gene sequencing company, Illumina Inc., to develop its next generation sequencing platform for companion diagnostic tests applicable across AstraZeneca’s oncology portfolio. Read more…

Amid ALS Mania, Possible Drug Target Spotted

August 21, 2014 3:02 pm | by Cynthia Fox, Science Editor | Articles | Comments

As, all around them, everyone from Derek Jeter to the Kennedy family was dousing themselves in...

Researchers Restore Protein in Muscular Dystrophy

August 21, 2014 11:19 am | News | Comments

For the first time, a research team has succeeded in restoring a missing repair protein in...

Ebola: Slum Calm; Aid Worker Recovers

August 21, 2014 11:12 am | by Jonathan Paye-Layleh, Associated Press | News | Comments

Calm returned Thursday to a slum in the Liberian capital that was sealed off in the government's...

View Sample

FREE Email Newsletter

Daily news and top headlines for drug research professionals

Novan’s Topical Treatment Shows Efficacy Against Drug-resistant Bugs

August 20, 2014 2:29 pm | News | Comments

Novan Therapeutics announced that the company’s Nitricil platform technology has been shown to be efficacious against several of the most multi-drug resistant pathogens plaguing civilian and military health care providers across the globe. Read more...

Novartis Licenses Candidate Compounds to TB Alliance

August 20, 2014 2:17 pm | News | Comments

Novartis has signed an exclusive worldwide licensing agreement with the Global Alliance for TB Drug Development (TB Alliance) for compounds to fight tuberculosis (TB). Read more...                    

New Vaccine Promising Weapon Against TB, Leprosy

August 20, 2014 2:09 pm | News | Comments

The currently available century-old vaccine Bacille Calmette-Guerin, or BCG, provides only partial protection against both tuberculosis and leprosy. Now, researchers may have found a stronger weapon against both diseases. Read more...     

Advertisement

Drug Candidate Blocks 'Chili-pepper Receptor'

August 20, 2014 1:59 pm | News | Comments

As anyone who has bitten into a chili pepper knows, its burning spicinesscan be intolerable. Scientists exploring the chili pepper’s effect are using their findings to develop a new drug candidate for many kinds of pain. Read more...     

Stemedica Posts Alzheimer’s Stem Cell Data

August 20, 2014 10:24 am | News | Comments

Stemedica International, a Stemedica Cell Technologies subsidiary developing stem cell therapies for Alzheimer’s disease and dementia, revealed the first results of an intravenous administration of allogeneic, human, ischemia-tolerant mesenchymal stem cells in a pre-clinical animal model of Alzheimer’s disease. Read more...

New Vaccines Can Cut Meningitis Spread by 39%

August 19, 2014 3:35 pm | News | Comments

Investigators have discovered that two new vaccines can prevent the transmission of meningitis bacteria from person to person. The vaccines do this by reducing "carriage" of the responsible bacteria in the nose and throats of the population. Read more...

Small Molecules, Stem Cells Can Improve Hearing

August 18, 2014 3:14 pm | by Cynthia Fox, Science Editor | Articles | Comments

A scientist has found that a compound, LY-411575, can restore 20% of hearing in deaf mice, or ten decibels. Since electroacoustic hearing aids, at best, improve hearing by five decibels, there is a “good chance” the work will lead to help for deafened patients.

Ruxolitinib Restores Hair in Alopecia Areata

August 18, 2014 2:28 pm | News | Comments

Researchers have identified the immune cells responsible for destroying hair follicles in people with alopecia areata, a common autoimmune disease that causes hair loss, and have tested an FDA-approved drug that eliminated these immune cells and restored hair growth in a small number of patients. Read more...

Advertisement

Watch Yourself: Device Data May Improve Parkinson's Research, Monitoring

August 15, 2014 2:01 pm | Videos | Comments

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and Intel Corporation announced a collaboration aimed at improving research and treatment for Parkinson’s disease. Read more...                  

New Focus on Drugs Made in Tobacco Plants

August 15, 2014 1:47 pm | by Malcolm Ritter, AP Science Writer | News | Comments

It's an eye-catching angle in the story of an experimental treatment for Ebola: The drug comes from tobacco plants that were turned into living pharmaceutical factories. Using plants this way- sometimes called "pharming"- can produce complex and valuable proteins for medicines. Read more...

Allergan Buys Bladder Treatment Program from TARIS Biomedical

August 14, 2014 3:17 pm | News | Comments

Allergan and TARIS Holdings announced that Allergan has closed a transaction to acquire worldwide rights to TARIS Biomedical's lead program, LiRIS, which is currently in Phase 2 trials for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). Read more...

Potential Drug Therapy for Kidney Stones Identified

August 14, 2014 3:10 pm | News | Comments

Anyone who has suffered from kidney stones is keenly aware of the lack of drugs to treat the condition, which often causes excruciating pain. Now, a new mouse study suggests that a class of drugs approved to treat leukemia and epilepsy also may be effective against kidney stones, researchers report. Read more...

Injection of Modified Bacteria Shrinks Tumors

August 14, 2014 3:00 pm | News | Comments

A modified version of the Clostridium novyi (C. novyi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report. Read more...              

Advertisement

Cardium's Gene Therapy 'Highly Warranted' for Heart Disease Subset

August 13, 2014 2:37 pm | News | Comments

Cardium Therapeutics announced the publication of a review article that concludes a gene therapy product promoting the growth of blood vessels is "highly warranted" to treat worldwide heart-disease patients. Read more...         

Heart Attack Drug Reduces Tissue Damage, Minimizes Bleeding Risk

August 13, 2014 2:13 pm | News | Comments

An investigational drug studied in animals significantly reduced damage to heart muscle from a heart attack and minimized the risk of bleeding during follow-up treatments, according to a new study. Read more...           

MJFF Highlights Promising Parkinson's Disease Drug Research

August 12, 2014 3:21 pm | News | Comments

Research projects from five groups active in Parkinson's research comprise the 2014 first half (1H 2014) of The Michael J. Fox Foundation for Parkinson's Research (MJFF) Partnering Program. Read more...                

Prosensa, CureDuchenne Strengthen Collaboration

August 12, 2014 11:38 am | News | Comments

Prosensa Holding N.V. announced that an affiliate of CureDuchenne will provide Prosensa with up to €5 million by means of convertible promissory notes to support the company and accelerate the development and patient access of much needed DMD therapies. Read more...

Discovery May Provide Key to Treating CHF

August 11, 2014 2:38 pm | News | Comments

Researchers have discovered a previously unknown cardiac molecule -- a long non-coding RNA called myosin heavy-chain-associated RNA transcript or Myheart  -- that could provide a key to treating, and preventing, heart failure. Read more...

TPM/Oxymorphone Patch Demonstrates Reproducibility

August 11, 2014 10:53 am | News | Comments

Australian drug delivery company, Phosphagenics Ltd. announced that the first of its additional studies designed to further characterize the TPM/Oxymorphone patch, in support of an Investigational New Drug (IND) application with the FDA has been completed. Read more...

Discovery IDs a New Class of Antibiotics

August 8, 2014 3:00 pm | News | Comments

St. Jude Children's Research Hospital scientists have discovered an enzyme -  fatty acid kinase - that regulates production of the toxins that contribute to potentially life-threatening Staphylococcus aureus infections. Read more...

Charity, Industry Join Forces on Pancreatic Cancer Drugs

August 8, 2014 10:35 am | News | Comments

Cancer Research UK and its commercial arm, Cancer Research Technology, are to join forces with Astellas Pharma Inc. to find new drug targets in the fight against cancer, with an initial focus on pancreatic cancer, one of the deadliest forms of cancer. Read more...

Splicing Modifiers May Correct Spinal Muscular Atrophy Deficit

August 8, 2014 10:03 am | News | Comments

The journal Science published results of a preclinical study demonstrating that treatment with orally available RNA splicing modifiers of the SMN2 gene starting early after birth is preventing deficits in mouse models of Spinal Muscular Atrophy. Read more...

Cure to Lung Cancer May Depend on Your DNA

August 7, 2014 1:00 pm | News | Comments

The Northside Hospital Cancer Institute announced its participation in a unique National Cancer Institute clinical collaboration to treat lung cancer based on a person’s genetic makeup. Read more...               

Takeda to Extend Global Reach

August 7, 2014 1:00 pm | News | Comments

New Takeda Pharmaceutical Co. President Christophe Weber said recently that Japan's biggest drugmaker will continue efforts to expand its business abroad through acquisitions and will outline a new strategy by the end of the year. Read more...  

New Drug Cures Arthritis in Mice

August 6, 2014 2:56 pm | News | Comments

With a new therapeutic product, researchers have managed to cure arthritis in mice for the first time. The scientists are now planning to test the efficacy of the drug in humans. Read more...                 

X
You may login with either your assigned username or your e-mail address.
The password field is case sensitive.
Loading