Advertisement
Drug Discovery
Subscribe to Drug Discovery

The Lead

Novel Drug Combo Improves Function of Cystic Fibrosis Protein

May 22, 2015 10:07 am | by Johns Hopkins | News | Comments

A novel two-drug combination has the potential to target and restore a defective protein underlying cystic fibrosis (CF), according to two phase 3 clinical trials conducted at 187 medical centers around the world, including Johns Hopkins. Read more...

1950s Drug is Future Heart Treatment

May 22, 2015 8:46 am | by University of Oxford | News | Comments

Researchers have found a promising future treatment for heart disease, going back to a drug...

Freshly Squeezed Vaccines

May 22, 2015 8:39 am | by MIT | News | Comments

Researchers have shown that they can use a microfluidic cell-squeezing device to introduce...

Injected T Cells from Bone Marrow Treat Multiple Myeloma, Pilot Study Finds

May 21, 2015 1:12 pm | by Stephanie Guzowski, Editor | Articles | Comments

In a first small clinical trial of its kind, researchers harnessed T cells from patients’ own...

View Sample

FREE Email Newsletter

Daily news and top headlines for drug research professionals

Chemo Before Surgery Benefits Patients with Advanced Ovarian Cancer

May 21, 2015 9:39 am | by Cancer Research UK | News | Comments

550 women with the disease took part in the trial, with 276 given the standard treatment of surgery followed by six cycles of chemotherapy, and 274 had surgery after three cycles of chemotherapy. Read more...

Brain Plaque Forecasts Alzheimer’s Years in Advance, Studies Confirm

May 20, 2015 1:49 pm | by Stephanie Guzowski, Editor | News | Comments

Brain plaques may appear up to 30 years prior to developing Alzheimer’s disease, according to the largest analysis to date of beta amyloid in people’s brains. Findings from two new meta-analyses  also confirm that amyloid screening, by PET scan or cerebral spinal fluid test, can help identify the best participants for clinical trials of Alzheimer’s drugs. Read more...

Key Component in Protein that Causes Cystic Fibrosis Identified

May 19, 2015 12:31 pm | by University of Missouri | News | Comments

Nearly 70,000 people worldwide are living with cystic fibrosis, a life-threatening genetic disease. There currently is no cure for the condition, but researchers from the University of Missouri have identified a key component in the protein that causes the disease. It is a finding that may lay the foundation for the development of new medications and improved therapies. Read more...

Advertisement

Groundbreaking Treatment for Patients with Cystic Fibrosis

May 18, 2015 11:15 am | by Lurie Children's Cystic Fibrosis Center | News | Comments

Treatment with two medications that target the most common genetic cause of cystic fibrosis improves lung function and lowers the rate of pulmonary exacerbations, according to the results from a Phase 3 international clinical trial published online in the New England Journal of Medicine. Read more...

Astellas Announces New Data from Phase 3 Study for OAB Drug

May 18, 2015 8:53 am | News | Comments

The results of the trial showed that the add-on group achieved its primary efficacy endpoints. Read more...

Lives Could Be Saved with New Hepatitis C Therapy

May 18, 2015 8:37 am | by Monash University | News | Comments

Hepatitis C virus infection is a major public health burden in Australia, with estimates of 230,000 people chronically infected. Read more...

Tuberculosis Drug Can Improve CBT Efficacy

May 18, 2015 8:31 am | by Karolinska Institutet | News | Comments

A new study shows that the effect of internet-based CBT (cognitive behavioural therapy) for people with people with obsessive-compulsive disorder (OCD) may be boosted with a drug called d-cycloserine, which has long been used to treat TB. Read more...

PharmaMar Announces New Oncology Advances with Yondelis, PM1183 Compounds

May 15, 2015 9:18 am | News | Comments

The studies were selected for oral discussion session and poster presentation at the American Society of Clinical Oncology's meeting later this month. Read more...

Advertisement

Findings Should Enhance Treatments for Stopping Immune System Attacks

May 15, 2015 9:12 am | by University of Manchester | News | Comments

Scientists have made an important discovery about an immune cell which is already being used in immunotherapy to treat diseases such as type I diabetes. Read more...

Scientists Discover Bacterial Cause Behind Fatal Heart Complications

May 15, 2015 9:06 am | by University of Liverpool | News | Comments

Researchers discover a key cause of life threatening heart complications, conditions that frequently follow severe infections with the bacteria responsible for pneumonia and meningitis. Read more...

Cancer Institute of NJ Investigates Promising Immunotherapy for Toughest Lung Cancers

May 14, 2015 11:47 am | by Seth Augenstein, Digital Reporter | Articles | Comments

Small-cell lung cancer, often caused by smoking, is among the most stubborn diseases in oncology. While it might respond initially to chemotherapy, it often recurs – and comes back even more resistant to treatment. But a new use of a known immunotherapy, bolstering the body’s immune system, is showing some promise against this disease, according to research taking place at the Rutgers Cancer Institute of New Jersey. Read more...

B Vitamin May Prevent Recurrence of Skin Cancers

May 14, 2015 11:33 am | by Ryan Bushey, Associate Editor | Articles | Comments

A study conducted by scientists at Australia’s University of Sydney found that a form of vitamin B3 has the potential to lower the chance of developing skin cancer. Read more...

Breakthrough Opens Door to Safer Lupus Drugs

May 14, 2015 9:08 am | by Monash University | News | Comments

Researchers could revolutionize treatments given to lupus sufferers, saving thousands of people each year from serious illness or death caused by secondary infections. Read more...

Advertisement

Roche Announces Phase 2 Study Results for Lung Cancer Immunotherapy

May 14, 2015 9:04 am | News | Comments

Roche announced interim results from a global, randomized Phase 2 study in people with previously treated NSCLC.  Read more...

Drug Target for Asthma Discovered

May 14, 2015 8:57 am | by Wellcome Trust Sanger Institute | News | Comments

The identification of this gene's role could help in the search for asthma therapies. Read more...

Researchers Find New Targets for Anti-Malaria Drugs

May 14, 2015 8:51 am | by MIT | News | Comments

A new target for drug development in the fight against the deadly disease malaria has been discovered by researchers at MIT. Read more...

AstraZeneca to Focus on Precision Medicine for Asthma, Heart Disease

May 13, 2015 9:50 am | by Ryan Bushey, Associate Editor | Articles | Comments

Abbot Laboratories and the Montreal Heart Institute will help the company with this project. Read more..

The Key to Stopping Sarcomas' Spread

May 13, 2015 8:26 am | by University of British Columbia | News | Comments

When sarcomas become large enough and outgrow their blood supply, they become vulnerable to hypoxia — a lack of oxygen. That adaptation not only enables them to survive the stress of low oxygen — it also enables them to withstand cancer drugs. Read more...

New Blood Test for Fibromyalgia Moves a Step Closer

May 13, 2015 8:24 am | by Arthritis UK | News | Comments

New research by scientists could lead to a blood test to diagnose fibromyalgia. Read more...

Tribeca Disruptive Innovation Awards: From Detecting HIV to Nanoscale Imaging

May 11, 2015 3:24 pm | by Cynthia Fox, Science Editor | Articles | Comments

In the spirit of its title, this year’s Tribeca Film Festival’s Disruptive Technologies awards ceremony did not distinguish between work that was only simple or complex; only big or small. It focused on work that angled to disrupt the norm, or “transcend limits,” said presenter and Tribeca Film Institute co-founder Craig Hatkoff. Read more...

Disrupting Cancer Pathway Could Enhance New Immunotherapies

May 11, 2015 11:26 am | by University of Chicago Medical Center | News | Comments

Understanding how to overrule a signaling pathway that can cause treatments to fail in metastatic melanoma patients should help physicians extend the benefits of recently approved immunity-boosting drugs known as checkpoint inhibitors to more patients. Read more..

GSK, UNC Team Up to Fight HIV

May 11, 2015 10:47 am | by Ryan Bushey, Associate Editor | Articles | Comments

Glaxo will spend a total of $20 million over the next five years to fund this endeavor.  Read more...

Nanotechnology Applications in Drug Delivery

May 8, 2015 4:28 pm | by Michael Morgen, Ph.D., Bend Research Inc., a division of Capsugel Dosage Form Solutions | Articles | Comments

In recent years nanotechnology has received significant interest for a wide range of applications, including those within the pharmaceutical industry.  In this area in particular, a number of diverse nano-sized structures have been investigated for drug formulation and delivery. Read more...

New Research into Health Benefits of Coffee

May 8, 2015 8:39 am | by Monash University | News | Comments

New research has brought us closer to being able to understand the health benefits of coffee. Read more...

Existing Drug May Treat Deadliest Childhood Brain Tumor, Study Finds

May 7, 2015 10:22 am | by Erin Digitale, pediatrics science writer for Stanford University | News | Comments

A multicenter study has identified an FDA-approved medication that prolongs survival in mice with diffuse intrinsic pontine glioma, a brain tumor that now lacks chemotherapy treatments. Read more...

X
You may login with either your assigned username or your e-mail address.
The password field is case sensitive.
Loading