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After Lung Transplant, Antiviral Drug Resistance More Likely in Cystic Fibrosis

December 19, 2014 1:50 pm | News | Comments

A drug called ganciclovir is given to lung transplant patients to protect against a life-threatening virus that is common after transplantation. Read more...                                                     

Fresh Setback For Efforts to Cure HIV Infection

December 18, 2014 8:12 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Researchers are reporting another disappointment for efforts to cure infection with the AIDS...

Despite Risks, Benzodiazepine Use Highest in Older People

December 17, 2014 4:50 pm | by NIH | News | Comments

Prescription use of benzodiazepines — a widely used class of sedative and anti-anxiety...

Occasional Heroin Use May Worsen HIV Infection

December 17, 2014 12:15 pm | News | Comments

Researchers at Yale and Boston University and their Russian collaborators have found that...

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Daily news and top headlines for drug research professionals

Teen Prescription Opioid Abuse Trend Down

December 16, 2014 11:27 am | by NIH | News | Comments

Use of cigarettes, alcohol, and abuse of prescription pain relievers among teens has declined since 2013 while marijuana use rates were stable, according to the 2014 Monitoring the Future (MTF) survey, released today by the National Institute on Drug Abuse (NIDA). However, use of e-cigarettes, measured in the report for the first time, is high. Read more...

'Darwinian' Test Uncovers an Antidepressant's Hidden Toxicity

December 16, 2014 10:14 am | by University of Utah | News | Comments

Because of undetected toxicity problems, about a third of prescription drugs approved in the U.S. are withdrawn from the market or require added warning labels limiting their use. An exceptionally sensitive toxicity test invented at the University of Utah could make it possible to uncover more of these dangerous side effects early in pharmaceutical development so that fewer patients are given unsafe drugs. Read more...

Study Shows Potential for Faster Drug Development

December 15, 2014 1:47 pm | News | Comments

A new study demonstrates the ability to conduct robust cardiac safety characterizations several years earlier than current practice. Read more...                    

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Hep C Ruled Out as Mental Impairment Cause in HIV

December 12, 2014 10:52 am | by Michael C. Purdy, Washington University | News | Comments

Advances in treatment for human immunodeficiency virus (HIV) have made it possible for people with HIV to survive much longer. As they age, however, many experience impaired thinking, memory loss, mood swings and other evidence of impaired mental function. Read more... 

Minnesota Board Won't Set Rules on Execution Drugs

December 11, 2014 2:09 pm | by Brian Bakst - Associated Press | News | Comments

Minnesota pharmacy regulators declined Wednesday to set a pioneering policy sought by death-penalty opponents that would explicitly bar the manufacture of lethal drugs for use in executions elsewhere. Read more...        

Ebola Vaccine Trial Suspended After Side Effects

December 11, 2014 9:17 am | by Associated Press | News | Comments

Swiss researchers have suspended the testing of one of the leading Ebola vaccine candidates after some volunteers reported unexpected side effects. Read more...                                

Targeting Enzyme May Reduce Chemo Drug's Cardiac Side Effects

December 10, 2014 4:56 pm | by Massachusetts General Hospital | News | Comments

MGH investigators identified two compounds that appear to block the cardiac damage caused by the important chemotherapy drug doxorubicin. Their report in the issue of Science Translational Medicine indicates that inhibiting the action of an enzyme that is key to the generation of cellular energy in mitochondria could prevent doxorubicin-induced damage to cardiac cells. Read more...

New HPV Vaccine Strengthens Cancer Protection

December 10, 2014 4:42 pm | by Associated Press | News | Comments

The drugmaker Merck & Co. Inc. has received approval for an updated version of its Gardasil vaccine that protects against an additional five strains of the virus that causes most cases of cervical cancer. Read more..                  

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Generic Antiepilepsy Drugs Have Minimal Differences: Study

December 10, 2014 12:32 pm | by University of Cincinnati | News | Comments

A comparison of two of the most disparate approved generic antiepileptic drugs found minimal differences when compared under rigorous testing procedures in people with epilepsy, according to research presented by a University of Cincinnati (UC) clinician-researcher. Read more...

New Analytics Tool Helps Hospitals Improve Antibiotic Usage

December 9, 2014 12:15 pm | News | Comments

Cardinal Health introduced a powerful new tool that gives pharmacists the ability to rapidly analyze antibiotic use trends. Read more...                     

Trial Launched to Evaluate Amgen and Merck's Melanoma Treatment

December 9, 2014 9:04 am | News | Comments

Amgen announced the initiation of a trial of a new melanoma treatment. Read more...                              

Tasigna Wins Over Gleevec in Ph+CML Patients

December 8, 2014 1:45 pm | News | Comments

Six-year results from Novartis' randomized Phase 3 study continue to demonstrate the superiority of Tasigna compared to Glivec. Read more...                   

Oregon Hospital: Medication Error Killed Patient

December 5, 2014 3:00 pm | by Gosia Wozniacka - Associated Press | News | Comments

An Oregon hospital is acknowledging that it administered the wrong medication to a patient, causing her death. Read more...                       

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Flu Vaccine May Be Less Effective This Winter

December 5, 2014 12:09 pm | by Mike Stobbe - AP Medical Writer | News | Comments

Officials say the vaccine does not protect well against the dominant strain seen most commonly so far this year. Read more...                       

Study: Strengthening Evidence of Connection Between Statin Use, Cataracts

December 3, 2014 12:35 pm | by Elsevier | News | Comments

Few classes of drugs have had such a transformative effect on the prevention of cardiovascular disease (CVD) as have statins, prescribed to reduce total cholesterol and low-density lipoprotein cholesterol. However, some clinicians have ongoing concerns regarding the potential for lens opacities (cataracts) as a result of statin use. Read more...

Researchers Study Alzheimer's Investigational Drug

December 3, 2014 12:13 pm | by University of Cincinnati | News | Comments

Researchers at the University of Cincinnati (UC) are among those who have accepted the challenge of easing the burden of Alzheimer’s disease. They are conducting a research study to assess the effect of a new investigational drug on memory and activities of daily living in people with mild to moderate Alzheimer’s. Read more...

World-First Aspirin Study Reaches New Milestone

December 3, 2014 10:07 am | by Monash University | News | Comments

Australia’s largest clinical trial is a step closer to revealing in 2018 whether healthy older people should or should not take aspirin to prevent or delay certain diseases. Read more...             

Novartis's Gilenya Fails to Treat Difficult Form of MS

December 1, 2014 9:04 am | News | Comments

Novartis announced that the Phase 3 INFORMS study in primary progressive multiple sclerosis (PPMS) did not show a significant difference between fingolimod and placebo on a combination of disability measures. The safety results were consistent with the well-characterized safety profile of fingolimod in relapsing MS (RMS). Read more...

Powdered Measles Vaccine Found Safe in Early Clinical Trials

November 25, 2014 12:51 pm | News | Comments

A measles vaccine made of fine dry powder and delivered with a puff of air triggered no adverse side effects in early human testing and it is likely effective. Read more...                             

BMS to Collaborate on Immunotherapy Evaluation

November 24, 2014 1:01 pm | News | Comments

BMS and Five Prime Therapeutics Inc. announced that they have entered into an exclusive clinical collaboration agreement to evaluate the safety, tolerability and preliminary efficacy of immunotherapy drugs. Read more...       

Children's Relentless Seizures Halted By New Drug

November 24, 2014 12:22 pm | by Marla Paul, Northwestern University | News | Comments

An investigational medication has been found to effectively treat children with life-threatening and difficult-to-control epileptic seizures without side effects. Read more...              

Amgen-Sponsored Gastric Cancer Studies Terminated

November 24, 2014 11:01 am | News | Comments

Amgen announced the termination of all Amgen-sponsored clinical studies of rilotumumab in advanced gastric cancer,  including the Phase 3 RILOMET-1 and RILOMET-2 studies. Read more...                                 

Sub-Standard Meds Flood Afghan Market

November 19, 2014 9:24 am | News | Comments

Up to 300 companies in Pakistan produce poor quality drugs exclusively for Afghanistan because their products do not meet Pakistani government standards. Read more...                

Preferred Drug Regimen for Preventing Mother-to-Child HIV Transmission

November 18, 2014 10:14 am | News | Comments

For HIV-infected women in good immune health, taking a three-drug regimen during pregnancy prevents mother-to-child HIV transmission more effectively than taking one drug during pregnancy, another during labor and two more after giving birth, an international clinical trial has found. Read more...

'Smart' Drugs Won't Make Smart People Smarter

November 13, 2014 12:46 pm | News | Comments

It is claimed one in five students have taken the 'smart' drug Modafinil to boost their ability to study and improve their chances of exam success. But new research into the effects of Modafinil has shown that healthy students could find their performance impaired by the drug. Read more...

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