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MicroBiome Therapeutics' Drug May Limit Metformin Side Effects

September 26, 2014 3:47 pm | News | Comments

MicroBiome Therapeutics reported positive topline results from a proof-of-concept study testing whether its investigational drug, NM 505, can improve the tolerability of metformin, the first-line therapy for Type 2 diabetes worldwide. Read more...

One in 10 Antibiotic Prescriptions Fail

September 26, 2014 3:09 pm | News | Comments

Over a 22-year period more than one in 10 of all...

Pacira Shares Drop as FDA Warns on Misleading Ads

September 25, 2014 2:13 pm | News | Comments

Pacira Pharmaceuticals Inc. said Thursday that it...

Anti-Addiction Groups Call for New FDA Chief

September 24, 2014 3:32 pm | by Matthew Perrone, AP Health Writer | News | Comments

Anti-addiction activists are calling for the Food...

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New FDA Label Bolsters Safety Case for Chantix

September 24, 2014 2:18 pm | by Matthew Perrone, AP Health Writer | News | Comments

New government-approved labeling on Pfizer's drug Chantix suggests that the anti-smoking medication may not carry the risks of suicidal behavior that first earned it the Food and Drug Administration's strongest warning more than five years ago. Read more...

NIH Funds Next Phase of Tissue Chip for Drug Screening Program

September 24, 2014 10:40 am | News | Comments

The National Institutes of Health will award funds to support the next phase of its Tissue Chip for Drug Screening program to improve ways of predicting drug safety and effectiveness. Read more...                            

FDA Warns Doctors to Beware Fake Drug Distributors

September 23, 2014 2:44 pm | by Matthew Perrone, AP Health Writer | News | Comments

U.S. health regulators are trying to help doctors spot counterfeit and unapproved drugs by raising awareness of illegal operations that peddle bogus drugs to health professionals. Read more...                 

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Metformin Linked to Risk of Low Levels of Thyroid Hormone

September 22, 2014 4:03 pm | News | Comments

Metformin, a commonly used drug for treating type 2 diabetes, is linked to an increased risk of low thyroid-stimulating hormone (TSH) levels in patients with underactive thyroids (hypothyroidism), according to a new study. Read more...      

Experts Want Limits on Testosterone Drug Use

September 17, 2014 6:39 pm | by Matthew Perrone, AP Health Writer | News | Comments

U.S. health experts said Wednesday there is little evidence that testosterone-boosting drugs are effective for treating common signs of aging in men and that their use should be narrowed to exclude millions of Americans currently taking them. Read more...

Method May Enable Portable Detection of ‘Bath Salts’

September 10, 2014 2:30 pm | News | Comments

Despite being outlawed in 2012 in the United States, the synthetic drugs known as “bath salts” are still readily available in some retail shops. To help law enforcement, scientists are developing a novel method that could be the basis for the first portable, on-site testing device for identifying the drugs. Read more...

Drug Safety Report Details 49,000 Undisclosed Side Effect Reports

September 10, 2014 1:45 pm | News | Comments

Healthcare informatics company AdverseEvents Inc. released a special drug safety report that includes an analysis of 48,971 unreleased FAERS reports. Read more...                         

Sleep, Anxiety Meds May Increase Alzheimer's Risk

September 10, 2014 10:23 am | News | Comments

Taking benzodiazepines (widely prescribed drugs to treat anxiety and insomnia) is associated with an increased risk of developing Alzheimer's disease, particularly for long-term users, suggests a new study. Read more...         

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FDA Lifts Partial Hold on OncoMed's Cancer Drug

September 5, 2014 2:52 pm | News | Comments

OncoMed Pharmaceuticals announced that the FDA removed the partial clinical hold on the company's ipafricept (FZD8-Fc, OMP-54F28) Phase 1 clinical trials. Read more...                        

Newly Approved Kidney Drug Gets Unexpected Safety Warning

September 5, 2014 2:34 pm | News | Comments

Keryx Biopharmaceuticals received approval Friday for a pill to treat complications of kidney disease in dialysis patients, but the company's stock fell as investors reacted to an unexpected safety warning in the drug's prescribing label. Read more...

Flu Vaccine Protects Mothers, Babies

September 5, 2014 10:53 am | News | Comments

A new study shows that the influenza vaccination of pregnant HIV-uninfected and HIV-infected women is safe and protects the women against confirmed influenza illness. Read more...                     

Takeda Ordered to Pay $6B in Diabetes Drug Case

September 4, 2014 10:26 am | News | Comments

Takeda Pharmaceutical Co. said Thursday it has been ordered by a U.S. district court to pay $6 billion in punitive damages over a lawsuit filed by a man who claimed his bladder cancer was caused by Takeda's diabetes medicine Actos. Read more...  

FDA: Little Evidence to Support Testosterone Drugs

September 3, 2014 2:56 pm | by Matthew Perrone | News | Comments

The FDA says there is little evidence that testosterone-boosting drugs taken by millions of American men are beneficial, though the agency is also unconvinced by studies suggesting the hormone carries serious risks. Read more...       

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HIV Drug Dosage May Be Ineffective for African-Americans

August 28, 2014 2:00 pm | News | Comments

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study suggests. The initial dosing studies, completed before the drug was licensed in 2007, included mostly European-Americans, who generally lack a protein that is key to removing maraviroc from the body. Read more...

New Statin Guidelines are an Improvement, Study Shows

August 26, 2014 3:18 pm | News | Comments

New national guidelines can improve the way statin drugs are prescribed to patients at risk for cardiovascular disease, a study has found. Read more...                             

Regado Biosciences Permanently Halts Phase 3 Trial

August 25, 2014 3:08 pm | News | Comments

Regado Biosciences Inc. announced the permanent termination of enrollment in its REGULATE-PCI Phase 3 trial for its lead program, Revolixys Kit. Read more...                           

‘The Pill’ Shrinks Ovaries, Cuts Egg Numbers

August 25, 2014 9:49 am | by Cynthia Fox, Science Editor | Articles | Comments

The birth control pill significantly affects ovarian reserve— or the number of immature eggs in a woman’s ovaries— which can be a predictor of future fertility, according to a team in Denmark. Read more...             

Alabama Ruling on Drug Warnings Draws Suspicion

August 23, 2014 11:25 am | by Jay Reeves | News | Comments

Business isn't buying the Alabama Supreme Court's attempt to limit the fallout from its decision saying brand-name drugmakers can be held liable for warnings on generic medication produced by other companies. Read more...         

New Hydrocodone Restrictions to Take Effect

August 21, 2014 1:00 pm | News | Comments

The federal government is finalizing new restrictions on hundreds of medicines containing hydrocodone, the highly addictive painkiller that has grown into the most widely prescribed drug in the U.S. Read more...            

Both American Ebola Patients Discharged from Hospital

August 21, 2014 1:00 pm | by Jeff Martin and Katie Foody | News | Comments

After nearly three weeks of treatment, the two American aid workers who were infected with the deadly Ebola virus in Africa have been discharged from an Atlanta hospital, officials said Thursday. Read more...            

DOJ Closes Probe into AstraZeneca Trial

August 19, 2014 3:26 pm | News | Comments

British drugmaker AstraZeneca says the U.S. Department of Justice has closed its investigation into a clinical trial of the company's blood thinner Brilinta, and plans no further action. Read more...               

HPV Vaccine Remains Effective After Eight Years, Study Says

August 18, 2014 2:39 pm | News | Comments

A new study examined whether the HPV vaccine remains effective 8 years after initial vaccination. The study followed boys and girls who were vaccinated with the HPV vaccine between the ages of 9 and 15. Read more...          

Liberia Gets ZMapp, Ponders Who Should Get It

August 14, 2014 2:50 pm | by Jonathan Paye-Layleh and Sarah DiLorenzo | News | Comments

Liberian officials faced a difficult choice Thursday: deciding which handful of Ebola patients will receive an experimental drug that could prove life-saving, ineffective or even harmful. Read more...               

Clinical Trial Evaluates Safety of Stem Cell Transplantation in Spine

August 12, 2014 2:41 pm | Videos | Comments

Researchers have launched a clinical trial to investigate the safety of neural stem cell transplantation in patients with chronic spinal cord injuries. This Phase 1 clinical trial is recruiting eight patients for the five-year study. Read more...

Ebola: Questions, Answers About Unproven Drug

August 12, 2014 2:25 pm | by Lauran Neergaard, AP Medical Writer | News | Comments

An experimental Ebola drug has been used to treat two American aid workers and a Spanish missionary priest, and the Liberian government said that it will receive doses of the drug to treat two doctors in the country. Read more...       

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