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The Lead

Indiana Governor Overrides Law to Authorize Needle Exchange

March 27, 2015 10:32 am | by Rick Callahan, AP | News | Comments

Indiana Gov. Mike Pence overrode state law and his own anti-drug policies Thursday to authorize a short-term needle-exchange program designed to help contain HIV infections in a rural county where more than six dozen cases have been reported, all of them tied to intravenous drug use. Read more...

FDA Approves Anthrax Treatment

March 25, 2015 1:10 pm | by Stephanie Guzowski, Editor | News | Comments

The Food and Drug Administration (FDA) yesterday approved Emergent BioSolutions’ infusible drug ...

Blood Test Could Help Bowel Cancer Patients Avoid Drug Side-Effects

March 25, 2015 8:33 am | by University of Manchester | News | Comments

Researchers have provided early evidence to suggest that a blood test could be used to identify...

Gilead Issues Safety Alert over Hepatitis C, Heart Drug Combination

March 24, 2015 12:03 pm | by Ryan Bushey, Associate Editor | Articles | Comments

Taking these medications together is ill-advised. Read more...

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Novartis' Cosentyx Shows Sustained Effect and Favorable Safety Profile

March 23, 2015 8:35 am | News | Comments

Novartis announced new two-year results demonstrating strong and sustained efficacy with Cosentyx. Read more...

NSAIDS and Cancer Risk

March 20, 2015 10:01 am | by Sue McGreevy, Harvard University | News | Comments

An analysis of genetic and lifestyle data from 10 large epidemiologic studies has confirmed that regular use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to reduce the risk of colorectal cancer in most individuals. Read more...

Are Antipsychotic Drugs more Dangerous to Dementia Patients Than We Think?

March 18, 2015 11:56 am | by University of Michigan | News | Comments

Drugs aimed at quelling the behavior problems of dementia patients may also hasten their deaths more than previously realized, a new study finds. Read more..

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New Hope for Kidney Disease

March 18, 2015 8:43 am | by Monash University | News | Comments

Researchers have made a discovery that could see patients with kidney disease no longer having to resort to dialysis or kidney transplants. Read more...

New System Made for Detecting Adverse Effects of Medications Using Social Media

March 17, 2015 8:55 am | by Universidad Carlos III de Madrid | News | Comments

Researchers have developed a system for detecting adverse effects of pharmaceutical drugs by tracking information generated by patients on specialized blogs or social networks such as Twitter in real time. Read more...

Diabetes Drug Shown Not to Increase Heart Failure Risk

March 13, 2015 12:17 pm | by University of Connecticut | News | Comments

People with the most common form of diabetes can take the new drug Alogliptin without concern for an increased risk of heart failure or cardiovascular disease, according to research by a UConn cardiologist published in the British medical journal, The Lancet. Read more..

Harder-to-Abuse OxyContin Doesn’t Stop Illicit Use

March 12, 2015 1:40 pm | by Jim Dryden, Washington University in St. Louis | News | Comments

A reformulation of OxyContin that makes it harder to abuse has curtailed the drug’s illicit use. But some 25 percent of drug abusers entering rehab said they still abused the prescription painkiller despite package labeling that emphasizes its abuse-deterrent properties, new research indicates. Read more...

d-Methadone: A Novel Approach for Neuropathic Pain

March 12, 2015 8:45 am | by Eliseo Salinas, MD, MSc, President and Chief Scientific Officer, Relmada Therapeutics | Articles | Comments

At a time when opioid abuse and addiction are making headlines, a new molecule is being studied to treat neuropathic pain without such negative effects. Read more...                        

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Rising Price of Heroin-Overdose Antidote Worries Advocates

March 10, 2015 12:52 pm | by Geoff Mulvihill and Andrew Welsh-Huggins, Associated Press | News | Comments

Price hikes are curtailing access to a popular form of an antidote to heroin overdoses, with costs doubling in the past year and the manufacturer's stock price rising by 70 percent since it went public. Read more...

FDA: Seizure, Alcohol Risk with Pfizer’s Chantix

March 10, 2015 11:59 am | by Stephanie Guzowski, Editor | Articles | Comments

The U.S. Food and Drug Administration (FDA) has determined it will not reduce the severity of its black-box warning about side effects associated with Pfizer’s smoking-cessation drug. Read more...                                                

New Test Uses Human Stem Cells to Identify Drug Side Effects

March 9, 2015 4:36 pm | by Sam Wong, Imperial College London | News | Comments

Scientists have developed a test that uses cells from a single donor's blood to predict whether a new drug will cause a severe reaction in humans. Read more...                 

Meet Thomas Goetz, The Co-founder of Iodine

March 5, 2015 11:50 am | by Ryan Bushey, Associate Editor | Articles | Comments

The startup has been called "The Yelp of Medicine." Read more...                                                         

Common Antidepressant May Hold Key to Heart Failure Reversal

March 5, 2015 10:51 am | by Temple University | News | Comments

This finding could lead to clinical trials for a disease long considered irreversible. Read more...                                             

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'Superbug' Infections Hit Another Los Angeles Hospital

March 5, 2015 10:12 am | by Alicia Chang, AP Science Writer | News | Comments

The latest cases occurred at Cedars-Sinai Medical Center. Read more...                                                     

Physicians May Have Underestimated Long-Term Risks of Taking Paracetamol

March 4, 2015 3:34 pm | by University of Leeds | News | Comments

Doctors may have underestimated the risks to patients of taking paracetamol on a long-term basis. Read more...                         

Study Shows Prescription Drug-Induced Liver Failure is Uncommon

March 4, 2015 3:27 pm | by University of Pennsylvania | News | Comments

This upends common belief that prescription drugs are prime culprits in causing liver failure. Read more...                         

Experts “Say No” to Behavior-Calming Drugs for Alzheimer's patients

March 3, 2015 12:14 pm | by University of Michigan | News | Comments

Doctors write millions of prescriptions a year for drugs to calm the behavior of people with Alzheimer’s disease and other types of dementia. But non-drug approaches actually work better, and carry far fewer risks, experts conclude in a new report. Read more...

An Opening for Measles

March 2, 2015 12:36 pm | by Colleen Walsh, Harvard Staff Writer | News | Comments

Anti-vaccination trend is becoming a growing concern. Read more...                                

Survey: Parents Increasingly Ask Doctors to Delay Vaccines

March 2, 2015 12:29 pm | by Lindsey Tanner, AP Medical Writer | News | Comments

Parents have increasingly pressured doctors to delay vaccines for young children, making their kids and others vulnerable to preventable diseases. Read more...                 

Heat Blamed for Spray Vaccine's Failure Against Swine Flu

February 27, 2015 12:53 pm | by Mike Stobbe, AP Medical Writer - Associated Press | News | Comments

The makers of the nasal spray version of the flu vaccine say now they know why it has failed to protect young U.S. children against swine flu - fragile doses got too warm. Read more...

First Independent U.S. Psoriasis Registry Will Track Drug Safety

February 26, 2015 11:09 am | News | Comments

People with psoriasis and their health care providers will have the opportunity to participate in research that aims to improve treatments and disease outcomes when the first independent U.S. psoriasis registry begins recruiting patients in 2015. Read more...

Watchdog Group Seeks FDA Ban of Antifungal Tablets

February 25, 2015 9:56 am | by Associated Press | News | Comments

A consumer safety group is calling on the Food and Drug Administration to pull certain antifungal tablets off the market, saying there are safer medicines that do not carry risks of liver damage. Read more.,.

Improving Patient Onboarding with Advancements in Medical Device Training

February 23, 2015 10:48 am | by Craig Baker, Executive Vice President, Noble | Articles | Comments

For some patients diagnosed with chronic medical conditions, weekly or biweekly self-administration using drug delivery devices is often a necessary component of a successful treatment program. Read more...

Closing the Knowledge Gap on Cancer Drug Toxicity

February 12, 2015 3:59 pm | by David Jackson, Ph.D., Chief Innovation Officer, MolecularHealth | Articles | Comments

There is a dangerous knowledge gap in the use of cancer medications that needs to be closed, immediately. Read more...                                                          

Engineered Insulin Could Offer Better Diabetes Control

February 10, 2015 11:58 am | by Anne Trafton, MIT | News | Comments

Engineers hope to improve treatment for diabetes patients with a new type of engineered insulin. Read more...                         

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