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The Lead

Laughing Gas Studied as Depression Treatment

December 9, 2014 3:22 pm | by Jim Dryden, Washington University in St. Louis | News | Comments

Nitrous Oxide has shown early promise as a potential treatment for severe depression in patients whose symptoms don’t respond to standard therapies. Read more...                 

Vaccine May Prevent Antibiotic Resistant Skin Infections

December 9, 2014 1:15 pm | News | Comments

Treatment is difficult because MRSA is resistant to many antibiotics, and the infections can...

Startup Aims to Develop 100 Drugs in 10 Years

December 9, 2014 12:59 pm | by University of Utah | News | Comments

A start-up wants to quickly and affordably identify unexpected ways a drug could be used by...

Flu Vaccine May Be Less Effective This Winter

December 5, 2014 12:09 pm | by Mike Stobbe - AP Medical Writer | News | Comments

Officials say the vaccine does not protect well against the dominant strain seen most commonly...

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A Hybrid Vehicle That Delivers DNA

November 26, 2014 12:00 pm | News | Comments

A new hybrid vehicle is under development. Its performance isn’t measured by the distance it travels, but rather the delivery of its cargo: vaccines that contain genetically engineered DNA to fight HIV, cancer, influenza and other maladies. Read more...

Pre-Empting Flu Evolution May Make Better Vaccines

November 21, 2014 9:37 am | News | Comments

An international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by ‘pre-empting’ the evolution of the influenza virus. Read more...           

New Approach for Treating ALS

November 20, 2014 1:45 pm | News | Comments

Researchers show that the brain’s machinery for pumping out toxins is ratcheted up in ALS patients. Read more...                         

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Chemical Disguise Transforms RNAi Drug Delivery

November 19, 2014 1:04 pm | News | Comments

Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery — it is extremely difficult to get RNAi drugs inside the cells in which they are needed.  Read more...

Method Developed for Detecting Tumor-Causing Mutations in Saliva

November 17, 2014 1:18 pm | News | Comments

Current methods to screen for lung cancer mutations in plasma or blood are complicated, technique-dependent and not readily available. Read more...                   

Tiny Needles Could Treat Two Major Eye Diseases

November 14, 2014 1:09 pm | by John Toon, Georgia Institute of Technology | News | Comments

Needles almost too small to be seen with the unaided eye could be the basis for new treatment options for two of the world’s leading eye diseases: glaucoma and corneal neovascularization. Read more...

New Imaging Method Could Improve Asthma Treatment

November 14, 2014 9:52 am | News | Comments

A team of researchers have used a laser beam trap to examine how drug particles from asthma inhalers behave. Read more...                       

Injectable Antidote for Carbon Monoxide Poisoning

November 13, 2014 1:10 pm | News | Comments

When Joseph Roderique was a first-year student in the Virginia Commonwealth University School of Medicine, he had an idea for an injectable antidote for carbon monoxide poisoning. It was a big idea, one that could have dramatic and wide-ranging results if he could make it work. Read more...

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When Tobacco Saved Lives

November 13, 2014 10:21 am | by Skip Derra | Articles | Comments

Will ZMapp’s Ebola success force big pharma to take plant-based drugs seriously? Read more...                                                      

AstraZeneca, Isis Pharmaceuticals to Co-Develop Targeted Delivery

November 13, 2014 9:57 am | News | Comments

Isis Pharmaceuticals Inc. and AstraZeneca announced a strategic alliance to discover and develop novel delivery methods for antisense oligonucleotides. The new delivery approaches seek to target the desired tissue more effectively. Read more...                   

Altered Milk Protein Can Deliver AIDS Drug to Infants

November 12, 2014 1:57 pm | by Jeff Mulhollem, Penn State | News | Comments

A novel method of altering a protein in milk to bind with an antiretroviral drug promises to greatly improve treatment for infants and young children suffering from HIV/AIDS, according to a researcher in Penn State's College of Agricultural Sciences. Read more...

Blood Test Could Reduce Antibiotic Use

November 12, 2014 12:20 pm | News | Comments

The key component of this test is a new blood biomarker test that indicates whether bacteria is the cause of a patient’s lung infection. Read more...                   

Gilead Submits Application for New HIV Pill to FDA

November 6, 2014 1:38 pm | News | Comments

Gilead submitted a new drug application that focuses on an experimental HIV pill. Read more...                                

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Google Developing Pill to Detect Cancer

October 29, 2014 12:46 pm | by Brandon Bailey - AP Technology Writer - Associated Press | News | Comments

Google is working on a cancer-detecting pill in its latest effort to push the boundaries of technology. Read more...                                          

BDSI Developing Long-Acting Vaccine for Pain Treatment

October 28, 2014 1:21 pm | News | Comments

BioDelivery Sciences International is developing a long-acting injectable for use in pain treatments. Read more...                        

Drugmakers Bet on Ebola Vaccines, Treatments

October 27, 2014 10:46 am | by Matthew Perrone and Danica Kirka - Associated Press | News | Comments

Drugmakers are racing to develop vaccines and drugs to address the worst outbreak of Ebola in history. Read more...                        

Study Finds Best Way to Treat Neck Pain

October 24, 2014 10:03 am | News | Comments

A multicenter study of 169 men and women with a common form of neck pain suggests that both spinal steroid injections and conservative treatment with physical therapy and painkillers work equally well to relieve pain in the short term. Read more...  

New Study Finds Potential Targets for Personalized Cancer Vaccines

October 23, 2014 10:01 am | News | Comments

A team of University of Notre Dame scientists, in collaboration with researchers at the University of Connecticut, have announced the results of a new study on identifying potential targets for personalized cancer vaccines. Read more...    

Microscopic “Walkers” Find Way Across Cell Surfaces

October 23, 2014 9:47 am | News | Comments

Technology could provide a way to deliver probes or drugs to cell structures without outside guidance. Read more...                                         

DNA-based ‘Nano-Cocoons’ Attack, Kill Cancer Cells

October 15, 2014 12:55 pm | News | Comments

Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale “cocoons” made of DNA that target cancer cells and trick the cells into absorbing the cocoon before unleashing anticancer drugs. Read more...

Researchers Begin Study of Ebola Vaccine in Africa

October 10, 2014 2:06 pm | News | Comments

The first study of a possible Ebola vaccine is underway in Africa: University of Maryland researchers say three health care workers in Mali received the experimental shots. Read more...

New COPD Inhalation Spray Now Available in U.S. Pharmacies

October 8, 2014 12:58 pm | News | Comments

Boehringer Ingelheim announced that Striverdi Respimat (olodaterol) Inhalation Spray 5 mcg is now available by prescription in pharmacies across the United States. Read more...                               

AbbVie's Humira Receives FDA Approval for JIA

October 6, 2014 3:04 pm | News | Comments

AbbVie announced that the FDA has approved the extension of the Humira indication for moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) to reducing signs and symptoms in patients ages 2 and older. Read more...

‘Programmable’ Antibiotic Harnesses Enzyme to Attack Drug-Resistant Microbes

October 6, 2014 10:12 am | News | Comments

The multitude of microbes scientists have found populating the human body have good, bad and mostly mysterious implications for our health. But when something goes wrong, we defend ourselves with the undiscriminating brute force of traditional antibiotics, which wipe out everything at once, regardless of the consequences. Read more...

Sanofi Signs 15-Year Supply Agreement for Wearable Injectors with Unilife

October 6, 2014 9:47 am | News | Comments

Unilife Corporation, a developer and supplier of injectable drug delivery systems, announced the signing of a worldwide Master Services and Commercial Supply Agreement with Sanofi to be the sole provider of cartridge based wearable injectors for all of Sanofi's applicable large dose volume drugs, excluding insulins, for a minimum 15 years. Read more...

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