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The Lead

Gold Nanoparticles Penetrate Cells, Show Promise for Drug Delivery

July 21, 2014 3:09 pm | Videos | Comments

A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells. Read more...                          

JDRF, ViaCyte File IND App for Diabetes Treatment Trial

July 18, 2014 3:30 pm | News | Comments

JDRF announced that ViaCyte Inc. has filed an Investigational New Drug application (IND) with...

Researchers Alleviate Pulmonary Inflammation Through Targeted Drug Delivery

July 15, 2014 2:43 pm | News | Comments

To date, no medication has been successful at preventing or mitigating the damage caused by...

Novartis to Use Google Technology for 'Smart' Contacts

July 15, 2014 2:19 pm | News | Comments

Swiss drug developer Novartis will team with technology giant Google to develop a "smart"...

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Tiny DNA Pyramids Enter Bacteria, Deliver Deadly Payload

July 10, 2014 12:00 pm | News | Comments

Bacterial infections usually announce themselves with pain and fever but often can be defeated with antibiotics— and then there are those that are sneaky and hard to beat. Now, scientists have built a new weapon against such pathogens in the form of tiny DNA pyramids. Read more...

Sandoz Launches Generic Diovan in the U.S.

July 9, 2014 11:24 am | News | Comments

Sandoz announced the U.S. introduction of an authorized generic version of Diovan (valsartan) tablets for the treatment of high blood pressure (HBP) and will market the authorized generic version of Diovan in the same strengths marketed for the branded version of Diovan. Read more...

Nanoparticles Can Enhance Cisplatin in Chemotherapy

July 8, 2014 2:19 pm | News | Comments

Researchers have developed a new formulation of cisplatin, a common chemotherapy drug, that significantly increases the drug's ability to target and destroy cancerous cells. Read more...                   

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Cancer-Fighting Patch to Treat Mouth Cancer

June 6, 2014 10:48 am | News | Comments

Researchers have signed an exclusive worldwide agreement with Venture Therapeutics Inc., to form a new company to develop and commercialize a pharmaceutical technology targeted for the treatment of precancerous oral lesions. Read more...    

Scientists Use New Method to Analyze Active Ingredients

June 5, 2014 1:58 pm | by Jonathan Agbenyega, Business Development Manager, IUCr | News | Comments

Active pharmaceutical ingredient (API), is the term used to refer to the biologically active component of a drug product whose behavior is of particularly high importance within the pharmaceutical industry and is vastly studied from every possible angle. Read more...

Nanoparticles Stagger Drug Delivery, Knock Out Aggressive Tumors

May 9, 2014 10:43 am | News | Comments

Researchers have devised a novel cancer treatment that destroys tumor cells by first disarming their defenses, then hitting them with a lethal dose of DNA damage. Read more...                     

Researchers ID New Formulation for Cancer Treatment

April 16, 2014 11:20 am | News | Comments

Researchers have discovered a new way to deliver a tricky drug, dichloroacetate, that may one day make it a viable treatment for numerous forms of cancer. Read more...                       

3-D Printed Tissues May Aid Drug Delivery, Wound Healing

April 16, 2014 11:13 am | News | Comments

A University of Oxford spin-out, OxSyBio, will develop 3-D printing techniques to produce tissue-like synthetic materials for wound healing and drug delivery. Read more...                       

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Nanoparticles Target Cancer with Triple Threat

April 15, 2014 12:10 pm | News | Comments

Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors, but it has been difficult to design particles that can carry any more than one or two drugs. Read more... 

USPTO Grants Hovione a New Inhaler Patent

April 8, 2014 1:27 pm | News | Comments

Hovione announced that the United States Patent and Trademark Office has granted a patent for a capsule-based, low-cost dry powder inhaler (DPI) to Hovione less than three years after the patent was filed and after just one Office Action– unusual speed for an inhaler application. Read more...

Gilead Hep C Combo Gets Breakthrough Therapy Status, Priority Review from FDA

April 7, 2014 2:21 pm | News | Comments

Gilead Sciences Inc. announced that the FDA has granted priority review and a Breakthrough Therapy designation to the comapny's fixed-dose combination of ledipasvir and sofosbuvir for the treatment of chronic hepatitis C genotype 1. Read more...

Nanoparticles Cause Cancer Cells to Self-Destruct

April 4, 2014 10:42 am | Videos | Comments

Using magnetically controlled nanoparticles to force tumor cells to "self-destruct: sounds like science fiction, but could be a future part of cancer treatment, according to new research. Read more...               

BioDelivery Sciences Opens Phase 3 Trial of Diabetic Neuropathy Gel

April 3, 2014 12:37 pm | News | Comments

BioDelivery Sciences International Inc. announced the enrollment of the first patient in the RHAPSODY Study, a Phase 3 clinical trial of Clonidine Topical Gel for the treatment of painful diabetic neuropathy. Read more...       

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FDA Approves First Hay Fever Immunotherapy Tablet

April 2, 2014 2:42 pm | by Linda Johnson, AP Business Writer | News | Comments

The Food and Drug Administration said Wednesday that it has approved the first tablet in the U.S. for gradually reducing hay fever symptoms, an alternative to months of weekly doctor visits for uncomfortable allergy-desensitizing shots. Read more...

Immunovaccine, Pfenex Post Positive Anthrax Vaccine Results

April 1, 2014 1:58 pm | News | Comments

Immunovaccine Inc. and Pfenex Inc. announced positive results from anthrax challenge studies in rabbits using Pfenex's mutant recombinant Protective Antigen (mrPA) formulated with Immunovaccine's DepoVax delivery system. Read more...   

Janssen Submits NDA for New HIV Combo Drug

April 1, 2014 1:38 pm | News | Comments

Janssen Research & Development LLC announced it has submitted a New Drug Application to the FDA seeking approval for a once-daily fixed-dose antiretroviral combination tablet containing darunavir, a protease inhibitor, with cobicistat, an investigational pharmacokinetic enhancer or boosting agent developed for use in combination with other human immunodeficiency virus (HIV-1) medicines. Read more...

How Personalized Medicine Works: Bananas and Biomarkers

March 20, 2014 11:13 am | Videos | Comments

In today's video, Andrew Wiecek discusses how personalized medicine works by highlighting the importance of biomarkers (and bananas) and showing that they play a key role in identifying genetic variations associated with disease.       

Fast Synthesis Could Boost Drug Development

March 19, 2014 3:10 pm | News | Comments

A major bottleneck has prevented peptide drugs from reaching their full potential: Manufacturing the peptides takes several weeks. But that bottleneck may soon disappear, as a team of chemists has designed a way to manufacture peptides in mere hours. Read more...

New Imaging Approach Speeds Prostate Cancer Drug Testing

March 18, 2014 10:26 am | News | Comments

Scientists have developed a new way to test the effectiveness of a drug for prostate cancer that has spread to the bone, which is currently incurable, according to new research. Read more...                 

Zyrtec Launched in New Dissolve Tabs

March 7, 2014 12:59 pm | News | Comments

The makers of Zyrtec are pleased to announce the launch of a new form to the Zyrtec portfolio of allergy-relief products– a convenient oral, dissolvable tablet. Read more...                      

The Benefits of Personalized Medicine: What Is It?

March 6, 2014 3:14 pm | Videos | Comments

Personalized medicine is a term you hear a lot in life science and drug industry discussions. Follow along as Rob Fee, Editor-in-Chief of Bioscience Technology, introduces the first video in a six-part series from both Drug Discovery & Development and Bioscience Technology that will explain what personalized medicine is, how it works and the potential of this concept.

Electronically Controlled Drugs Could Minimize Side Effects

March 5, 2014 2:36 pm | News | Comments

Potential side effects of many of today’s therapeutic drugs can be downright frightening — just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way.

Scientists Develop New Nanoscale Method to Fight Cancer

February 28, 2014 12:55 pm | News | Comments

Researchers have developed an innovative cancer-fighting technique in which custom-designed nanoparticles carry chemotherapy drugs directly to tumor cells and release their cargo when triggered by a two-photon laser in the infrared red wavelength. Read more...

Caffeine-Based Gold Compounds Potentially Fight Cancer

February 26, 2014 2:56 pm | News | Comments

Researchers report that combining a caffeine-based compound with a small amount of gold could someday be used as an anticancer agent. Read more...                              

Sustainable Method to Create Anticoagulants Discovered

February 26, 2014 11:13 am | News | Comments

Researchers have found a new way to manufacture an important molecule used in the pharmaceutical industry to create anticoagulants, a class of drug commonly prescribed to treat or prevent abnormal blood clots. Read more...        

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