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The Lead

Doctor Fights Overpopulation with Nonsurgical Contraceptive

May 22, 2015 9:40 am | by Seth Augenstein, Digital Reporter | News | Comments

An Oregon doctor is researching a non-surgical, permanent contraceptive method for women in developing countries, with some funding from the Gates Foundation. The work is being done with an eye toward curbing overpopulation, and to improve quality of life in impoverished countries, they said. Read more..

Freshly Squeezed Vaccines

May 22, 2015 8:39 am | by MIT | News | Comments

Researchers have shown that they can use a microfluidic cell-squeezing device to introduce...

Promising Malaria and Dengue Vaccines Will Not Defeat Diseases

May 20, 2015 8:54 am | by Christopher J. Pace, Ph.D., GlobalData Managing Analyst, Infectious Diseases | Articles | Comments

Some industry pundits rightfully question the modest protective efficacies of CYD-TDV and RTS,S/...

Roche Gains FDA CLIA Waiver for Strep A Test

May 19, 2015 8:39 am | News | Comments

CLIA waiver allows for broad use of the test by healthcare providers in non-traditional...

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The Key to Stopping Sarcomas' Spread

May 13, 2015 8:26 am | by University of British Columbia | News | Comments

When sarcomas become large enough and outgrow their blood supply, they become vulnerable to hypoxia — a lack of oxygen. That adaptation not only enables them to survive the stress of low oxygen — it also enables them to withstand cancer drugs. Read more...

Nanotechnology Applications in Drug Delivery

May 8, 2015 4:28 pm | by Michael Morgen, Ph.D., Bend Research Inc., a division of Capsugel Dosage Form Solutions | Articles | Comments

In recent years nanotechnology has received significant interest for a wide range of applications, including those within the pharmaceutical industry.  In this area in particular, a number of diverse nano-sized structures have been investigated for drug formulation and delivery. Read more...

New Malaria Vaccine Shows Promise in Field Trial

May 7, 2015 8:38 am | by University of Oxford | News | Comments

Following a trial in Kenya, the vaccine was found to be 67 percent effective against infection with Plasmodium falciparum, one of the parasites known to cause Malaria. Read more...

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Microneedle Patch for Measles Vaccination Could be Global Game Changer

April 28, 2015 8:45 am | by Georgia Institute of Technology | News | Comments

A new microneedle patch could make it easier to vaccinate people against measles and other vaccine-preventable diseases. Read more...

Innovation Gives Pregnant Women with Diabetes Round-the-Clock Glucose Control

April 27, 2015 9:02 am | by University of Leeds | News | Comments

Achieving better glucose control in pregnant women with diabetes by using continuous glucose monitoring may help them give birth to healthier children. Read more...

Final Trial Results of the World's Most Advanced Malaria Vaccine

April 27, 2015 8:58 am | by London School of Hygiene & Tropical Medicine | News | Comments

The results suggest that the vaccine could prevent a substantial number of cases of clinical malaria, especially in areas of high transmission. Read more...

Weaker Vaccine Causing Whooping Cough Surge

April 27, 2015 8:45 am | by Monash University | News | Comments

A Monash University expert has teamed up with the United States Centers for Disease Control and Prevention to pinpoint the reason behind a surge in whooping cough cases over the past 10 years. Read more....

How to Identify Drugs that Work Best for Each Patient

April 24, 2015 11:53 am | by Anne Trafton, MIT News | News | Comments

Implantable device could allow doctors to test cancer drugs in patients before prescribing chemotherapy. Read more...

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Hope for an Effective Malaria Therapy with Just One Tablet

April 24, 2015 8:54 am | by Medical University of Vienna | News | Comments

Approximately 584,000 people worldwide die of malaria each year. Read more...

WHO: Global Vaccination Records 'Off-Track'

April 23, 2015 8:45 am | News | Comments

Progress towards global vaccination targets for 2015 is far off-track with 1 in 5 children still missing out on routine life-saving immunizations that could avert 1.5 million deaths each year from preventable diseases. Read more...

Electronic Micropump Could Deliver Treatment to Specific Brain Region

April 17, 2015 10:13 am | by Stephanie Guzowski, Editor | News | Comments

There is an exactness that must be taken into account when treating neurological disorders. In treating epilepsy, for example, a condition in which nerve cell activity in the brain is disturbed, causing seizures, a drug needs to be delivered directly to a specific brain region—but without negatively affecting healthy brain regions. Read more...

Isarna Initiates First-in-Human Phase I Trial for Drug to Treat Advanced Glaucoma

April 17, 2015 8:11 am | News | Comments

The trial will enroll approximately 24 - 30 patients. Read more...

FDA Accepts Teva's NDA for Bendamustine

April 15, 2015 9:16 am | News | Comments

This NDA requests FDA approval of the rapid infusion bendamustine HCl product for the treatment of patients with chronic lymphocytic leukemia. Read more...

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New Liver Cancer Treatment Approved in Europe

April 15, 2015 8:24 am | by University Medical Center Utrecht | News | Comments

A new treatment for liver cancer developed by the University Medical Center Utrecht has received the European CE mark for quality and safety. Read more...

Biologists Identify Brain Tumor Weakness

April 9, 2015 8:42 am | by Anne Trafton, MIT | News | Comments

Biologists have discovered a vulnerability of brain cancer cells that could be exploited to develop more-effective drugs against brain tumors. Read more...

Allergy Drug Inhibits Hepatitis C in Mice

April 9, 2015 8:41 am | by National Institute of Health | News | Comments

An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice. Read more...

Scientists Identify Receptor for Asthma Associated Virus

April 6, 2015 5:01 pm | by National Institute of Allergy and Infectious Disease | News | Comments

Scientists have identified a cellular receptor for rhinovirus C. Read more...

Two Compounds Target the Gut to Lower Blood Sugar

April 6, 2015 4:32 pm | by Toronto General Hospital Research Institute | News | Comments

Researchers have discovered metformin and resveratrol trigger novel signaling pathways in the small intestine to lower blood sugar. Read more...

New Developments in Characterizing Protein-Small Molecule Interactions for Drug Discovery

April 6, 2015 4:26 pm | by Bill Sawka, MicroCal Product Manager, Malvern Instruments & Natalia Markova, Principal Scientist – MicroCal, Malvern Instruments | Articles | Comments

Isothermal titration calorimetry (ITC) is a highly valuable technique that is used throughout drug discovery workflow to study the binding interactions of proteins and small molecules. It is an essential tool for both drug design and the study and regulation of protein interactions. Read more...

Cane Toads Potentially Lucrative Export in Cancer Fight

March 26, 2015 4:12 pm | by University of Queensland | News | Comments

Scientists are exploring how cane toad venom can be used to fight cancer. Read more...

GSK Gains Japanese Approval for COPD Therapy

March 26, 2015 8:25 am | News | Comments

Following this approval, it is expected that launch will take place in Japan in 2015. Read more...

Study Announces Durable Ebola Vaccine

March 25, 2015 2:10 pm | by Andrew Gould, University of Plymouth | News | Comments

A new study shows the durability of a novel CMV-based Ebola virus vaccine strategy that may eventually have the potential to reduce ebola virus infection in wild African ape species. Read more...

Takeda Licenses Rights to Use Immunogen's Technology to Develop Anticancer Therapies

March 25, 2015 8:44 am | News | Comments

Takeda will use the technology to develop and commercialize targeted anticancer therapeutics to up to two undisclosed  targets. Read more...

Blood Test Could Help Bowel Cancer Patients Avoid Drug Side-Effects

March 25, 2015 8:33 am | by University of Manchester | News | Comments

Researchers have provided early evidence to suggest that a blood test could be used to identify bowel cancer patients that may benefit from more intensive chemotherapy. Read more...

New Hopes for Rheumatic Fever Vaccine

March 23, 2015 8:26 am | by University of Auckland | News | Comments

A new vaccine to combat the debilitating disease caused by rheumatic fever may soon become a reality, saving hundreds of thousands of deaths from preventable heart disease around the world each year. Read more...

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