Ardea Biosciences has received a $7.5 million payment from Bayer HealthCare, its partner on an experimental cancer drug, BAY 86-9766, which Ardea discovered.
Sorbent Therapeutics Inc. said that CLP1001 demonstrated improvement in heart failure symptoms as compared to placebo in a Phase 2a clinical study.
A Phase 3 study has demonstrated the long-term maintenance of efficacy of lisdexamfetamine dimesylate in children and adolescents with attention-deficit/hyperactivity disorder.
Boehringer Ingelheim and Eli Lilly announced Phase 3 study results for linagliptin, which showed a significant HbA1c reduction of 0.88% compared to 0.24% in the placebo group.
Acacia Pharma announces positive results from its double-blind Phase 2 study of APD421, in the prevention of post-operative nausea and vomiting.
Boehringer Ingelheim announced results from a Phase 2 study evaluating tiotropium delivered daily via the Respimat Inhaler in adolescents with symptomatic, moderate persistent asthma.
MorphoSys AG and Xencor Inc. announced the successful completion of patient enrollment in the Phase 1 clinical trial evaluating MOR208.
Cisbio Bioassays has added three kinase assays to its cell-based kinase screening platform for the study of different signaling pathways in drug discovery research.
HyperAcute Pancreas is currently being evaluated in a multi-institution, randomized, Phase 3 clinical trial under a Special Protocol Assessment with the FDA.
ArQule Inc. and Daiichi Sankyo Co. Ltd. announced that a Phase 2 trial using tivantinib as a second-line treatment in hepatocellular carcinoma met its primary endpoint.
Genta Incorporated announced results from its Phase 2 clinical trial using tesetaxel as initial, single-agent chemotherapy in women with advanced breast cancer.
Find contract research organizations (CROs) for Drug Discovery Services in the 2012 CRO/CMO Directory, from Drug Discovery & Development magazine.
Find contract research organizations (CROs) for Preclinical Services in the 2012 CRO/CMO Directory, from Drug Discovery & Development magazine.
Sandia Biotech's split-Green Fluorescent Protein technology allows researchers to analyze proteins and peptides with greater accuracy and fewer steps than current methods.
Catalyst Pharmaceutical Partners Inc. announced positive results from a Phase 1a study to evaluate the safety, tolerability and pharmacokinetic profile of CPP-115.
NovaBay Pharmaceuticals Inc. has enrolled the first patients in its Phase 2b clinical study to evaluate its lead compound NVC-422, for treating adenoviral conjunctivitis.
A cancer treatment from Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals Inc. failed to improve overall survival in patients with advanced cases of lung cancer.
Cancer Research UK's Drug Development Office has begun a trial of a drug combination in patients with advanced solid tumors and in patients with non-small cell lung cancer.
Elevation Pharmaceuticals Inc. announced positive results from a Phase 2b study of EP-101 in patients with chronic obstructive pulmonary disease.
Theraclone Sciences Inc. announced positive data from its Phase 1 trial of TCN-032, a broadly protective, fully human monoclonal antibody, for the treatment of influenza A infections.
Ark Therapeutics Group plc has completed the dose ranging Phase 1 section of the academic study of Ark’s VEGF-D adenoviral vector treatment for refractory angina.
Natural Product Purification of Lycopene and β‐Carotene Using Flash Column Sample Clean‐up Prior to High Pressure Normal Phase Chromatography on the Gilson PLC 2020May 16, 2012 3:25 pm | White Papers | Comments
Purifying low level compounds, such as those typically isolated from natural products, is an area of growing interest for the purpose of discovering new chemical entities.
In order to foster innovation, reduce costs, and halt the erosion of revenue, major pharmaceutical companies are exploring a range of new and emerging research arrangements.
Pharmacokinetics plays a crucial role in a compound’s efficacy and safety and to characterize the pharmacokinetics of a compound, accurate measurements are needed.