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Daily news and top headlines for drug research professionals

Abivax Completes First-In-Man Study of HIV Treatment

December 1, 2014 10:55 am | News | Comments

Abivax, a leading clinical stage biotech company developing and commercialising anti-viral compounds and human vaccines, announced the successful completion of its Phase 1 first-in-man study of ABX464, which has been designed to potentially deliver a number of important clinical benefits when treating patients with HIV. Read more...

Who Will Miss Ebola Targets Set for Dec 1?

December 1, 2014 9:26 am | by Maria Cheng, AP Medical Writer - Associated Press | News | Comments

Two months ago, the World Health Organization launched an ambitious plan to stop the deadly Ebola outbreak in West Africa, aiming to isolate 70% of the sick and safely bury 70% of the victims in the three hardest-hit countries - Guinea, Liberia and Sierra Leone - by December 1. Read more...

Eli Lilly, AstraZeneca Launch Patient Trial for Alzheimer's Treatment

December 1, 2014 9:17 am | News | Comments

Eli Lilly and Company and AstraZeneca announced enrollment of the first patient into Amaranth, a Phase 2/3 study of an oral beta secretase cleaving enzyme (BACE) inhibitor currently in development as a potential treatment for Alzheimer's disease. Read more...

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Novartis's Gilenya Fails to Treat Difficult Form of MS

December 1, 2014 9:04 am | News | Comments

Novartis announced that the Phase 3 INFORMS study in primary progressive multiple sclerosis (PPMS) did not show a significant difference between fingolimod and placebo on a combination of disability measures. The safety results were consistent with the well-characterized safety profile of fingolimod in relapsing MS (RMS). Read more...

Cloning Pioneer Proposes Global Network of IPS Cell Banks

November 28, 2014 9:55 am | by Cynthia Fox, Science Editor | Articles | Comments

Ian Wilmut, father of the cloned Dolly the Sheep, is now proposing to father a global induced pluripotent stem (iPS) cell handbook— to go with a proposed new global network of iPS cell haplobanks. Read more...                                   

A Hybrid Vehicle That Delivers DNA

November 26, 2014 12:00 pm | News | Comments

A new hybrid vehicle is under development. Its performance isn’t measured by the distance it travels, but rather the delivery of its cargo: vaccines that contain genetically engineered DNA to fight HIV, cancer, influenza and other maladies. Read more...

A Reason to be Thankful: Turkeys May be Lifesavers

November 26, 2014 12:00 pm | News | Comments

While the turkey you eat on Thursday will bring your stomach happiness and could probably kick-start an afternoon nap, it may also save your life one day. Read more...                        

Big Data to Make Big Difference in Childhood Cancer Treatment

November 26, 2014 12:00 pm | News | Comments

Research crunching vast amounts of data on childhood cancer to better tailor treatment is one step closer to assisting clinicians through a collaboration that boasts a virtual pipeline that visualizes large quantities of patient data to help hospital clinicians better diagnose and treat childhood cancer patients.

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First-in-Human Study of Antibody for AML Kicks Off

November 26, 2014 12:00 pm | News | Comments

Oxford BioTherapeutics and Berlin Chemie/Menarini Biotech/Menarini Ricerche announced that they have initiated the first-in-human clinical study of OBT357 (MEN1112), a novel enhanced antibody for the treatment of acute myeloid leukemia (AML). Read more...

The Cystic Fibrosis Foundation's Controversial New Cash

November 26, 2014 12:00 pm | by Ryan Bushey, Associate Editor | Articles | Comments

Concerns have been raised relating to a lucrative investment the Cystic Fibrosis Foundation made in a biotechnology company. Read more...                    

Chinese-Built Ebola Center Dedicated in Liberia

November 26, 2014 12:00 pm | by Jonathan Paye-Layleh and Clarence Roy-Macaulay, Associated Press | News | Comments

China, one of the first countries to send aid to battle Ebola in West Africa, ramped up the assistance significantly Tuesday by opening a 100-bed treatment center in Liberia as rows of uniformed Chinese army medics stood at attention.      

Study Proves Dificlir Is Effective for CDI Treatment

November 26, 2014 10:16 am | News | Comments

New analysis from a unique real-world study demonstrates that first-line use of fidaxomicin, is clinically effective in reducing recurrence rates and lowering mortality. Read more...              

C3BS Nominates Investigators for Clinical Trial of Heart Failure Treatment

November 26, 2014 9:56 am | News | Comments

Cardio3 BioSciences announces the appointment of its three Co-Principal Investigators for the study of its heart failure treatment. Read more...                   

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Public Health Interventions Needed to Tackle 'Lifestyle' Diseases

November 26, 2014 9:31 am | News | Comments

Interventions such as the smoking ban help to break habits instead of relying on individuals to make the right decision for their health. Read more...                   

Italy's Ebola Patient Gets Experimental Treatment

November 26, 2014 9:21 am | News | Comments

An Italian doctor who contracted Ebola while working in Sierra Leone has arrived back in Italy and is being treated with the same experimental drugs. Read more...                 

Amgen, AstraZeneca Announce Positive Study Results for Plaque Psoriasis Drug

November 26, 2014 9:13 am | News | Comments

Amgen and AstraZeneca announced positive phase 3 study results for plaque psoriasis drug. Read more...                           

Transposagen, Janssen to Collaborate on CAR-T Therapies

November 25, 2014 1:46 pm | by Drug Discovery & Development Staff | News | Comments

Transposagen Biopharmaceuticals, Inc., a private biotechnology company headquartered in Lexington, KY, announced they have entered into a research collaboration and worldwide license agreement with Janssen Biotech, Inc. to develop allogeneic Chimeric Antigen Receptor T-cells (CAR-T). Read more...

Powdered Measles Vaccine Found Safe in Early Clinical Trials

November 25, 2014 12:51 pm | News | Comments

A measles vaccine made of fine dry powder and delivered with a puff of air triggered no adverse side effects in early human testing and it is likely effective. Read more...                             

Drugs to Block Angiogenesis Could Provide New TB Treatment

November 25, 2014 12:36 pm | News | Comments

The body responds to tuberculosis infection by locking the bacterial offenders into tiny clusters of immune cells called granulomas, which are a hallmark of the disease. This containment strategy succeeds at first, but eventually the bacteria manage to break out of these intercellular jails and spread throughout the body. Read more...

How Environment Contributes to Human Diseases

November 25, 2014 12:22 pm | News | Comments

Using a new imaging technique, National Institutes of Health researchers have found that the biological machinery that builds DNA can insert molecules into the DNA strand that are damaged as a result of environmental exposures. Read more...                

Protein Key to Development of Blood Stem Cells Identified

November 25, 2014 12:13 pm | by Peter Bracke, UCLA | News | Comments

Understanding the self-replication mechanisms is critical for improving stem cell therapies for blood-related diseases and cancers. Read more...                                           

$1B Alliance Between Menarini, Oxford BioTherapeutics for Enhanced AML Treatment

November 25, 2014 10:04 am | News | Comments

This is the first of five development programs between the two companies to enter the clinic in a $1 billion strategic oncology alliance. Read more...                   

Vascular Solutions Gets Clearance for Tumor Treating Gel-Block

November 25, 2014 9:44 am | News | Comments

Vascular Solutions gets clearance from the FDA for tumor treating gel blocks. Read more...                             

Genetic Test Unlocks Cause of Brisbane Boy's Rare Disease

November 25, 2014 9:24 am | News | Comments

Queensland researchers have led an international effort to uncover the gene behind a young Brisbane boy’s rare developmental condition. Read more...                   

Researchers Identify New Ways to Drain Cancer's 'Fuel Tank'

November 25, 2014 9:07 am | News | Comments

Scientists at the University of Manchester have discovered a potential weakness in cancer’s ability to return or become resistant to treatment. Read more...                  

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