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Daily news and top headlines for drug research professionals

Mali Confirms Eighth Ebola Case

November 25, 2014 8:59 am | News | Comments

Mali has confirmed a new case of Ebola, bringing to eight the number of people who have fallen ill with the deadly disease in the West African country. Read more...                

Exciting Gains in Fighting Breast Cancer Hormone-Therapy Resistance

November 25, 2014 8:55 am | by Cynthia Fox, Science Editor | Articles | Comments

Guided by breakthrough research on the Estrogen Receptor 1 (ESR1) gene, many researchers and pharmaceutical companies are in hot pursuit of the next big anti-resistance breast cancer drug. Read more...                 

Improving The Odds of Beating Opioids

November 24, 2014 1:16 pm | by Sue McGreevy, Harvard University | News | Comments

Research indicates that live-in programs may result in higher levels of abstinence than the outpatient treatment that is currently the standard of care. Read more...                

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BMS to Collaborate on Immunotherapy Evaluation

November 24, 2014 1:01 pm | News | Comments

BMS and Five Prime Therapeutics Inc. announced that they have entered into an exclusive clinical collaboration agreement to evaluate the safety, tolerability and preliminary efficacy of immunotherapy drugs. Read more...       

New Drugs from Fish Oil Could Aid Artery Repair

November 24, 2014 12:33 pm | by Kathleen Masterson, University of California San Francisco | News | Comments

A common class of naturally occurring molecules from fish oil could help with artery repair. Read more...                         

Children's Relentless Seizures Halted By New Drug

November 24, 2014 12:22 pm | by Marla Paul, Northwestern University | News | Comments

An investigational medication has been found to effectively treat children with life-threatening and difficult-to-control epileptic seizures without side effects. Read more...              

Amgen-Sponsored Gastric Cancer Studies Terminated

November 24, 2014 11:01 am | News | Comments

Amgen announced the termination of all Amgen-sponsored clinical studies of rilotumumab in advanced gastric cancer,  including the Phase 3 RILOMET-1 and RILOMET-2 studies. Read more...                                 

EU Approves Novartis' Signifor Drug for Rare Hormonal Disorder

November 24, 2014 10:38 am | News | Comments

Novartis announced today that the European Commission has approved Signifor (pasireotide) as a new long acting release formulation for once monthly intramuscular injection to treat adult patients with acromegaly for whom surgery is not an option or has not been curative and who are inadequately controlled on treatment with a first-generation somatostatin analogue (SSA).  Read more...

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U.S. Looking Past Ebola to Prepare for Next Outbreak

November 24, 2014 9:25 am | by Lauran Neergaard, AP Medical Writer - Associated Press | News | Comments

The next Ebola or the next SARS. Maybe even the next HIV. Even before the Ebola epidemic in West Africa is brought under control, public health officials are girding for the next health disaster. Read more...                 

Plague Outbreak Kills 40 People in Madagascar

November 24, 2014 9:20 am | by Lynsey Chutel - Associated Press | News | Comments

A plague outbreak has killed 40 people on the island nation of Madagascar, with 119 people diagnosed with the bacterial disease since August. Read more...                                                                                

Neurotrope: Last Patient Dosed in Phase 2a Alzheimer's Study

November 21, 2014 11:41 am | News | Comments

Neurotrope, Inc. announced that the last patient has been dosed in its Phase 2a clinical trial of Bryostatin-1 for the treatment of patients with Alzheimer's disease (AD). The trial is being conducted under an Investigational New Drug (IND) application filed by the Company's licensor, the Blanchette Rockefeller Neuroscience Institute (BRNI). Read more...

Researcher Who Found Cause of Lyme Disease Dies

November 21, 2014 11:32 am | by Associated Press | News | Comments

The Swiss-born researcher who gained international recognition for discovering the bacteria that causes Lyme disease has died in western Montana. A spokesman at the Daly-Leach Chapel said Wilhelm "Willy" Burgdorfer died from complications of Parkinson's disease Monday in Hamilton. He was 89. Read more...

FDA Approves New, Hard-to-Abuse Hydrocodone Pill

November 21, 2014 11:27 am | by Matthew Perrone, AP Health Writer - Associated Press | News | Comments

Federal health regulators on Thursday approved the first hard-to-abuse version of the painkiller hydrocodone, offering an alternative to a similar medication that has been widely criticized for lacking such safeguards. Read more...

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Powerful Method to Speed Cancer Drug Discovery

November 21, 2014 11:22 am | by Salk Institute | News | Comments

For decades, researchers have struggled to translate basic scientific discoveries about cancer into therapeutics that effectively–and with minimal side effects–shrink a tumor. Read more...

HIV/AIDS Drugs Could Be Repurposed to Treat AMD

November 21, 2014 11:01 am | by Ann Blackford, University of Kentucky | News | Comments

A study published in the journal Science by an international group of scientists, led by the laboratory of Dr. Jayakrishna Ambati, professor and vice chair of the Department of Ophthalmology & Visual Sciences at the University of Kentucky, reports that HIV/AIDS drugs that have been used for the last 30 years could be repurposed to treat AMD. Read more...

UK Investment to Develop Lung Cancer Drugs

November 21, 2014 9:58 am | News | Comments

A new collaboration in the UK will develop a promising class of cancer inhibitors. Read more...                            

Pre-Empting Flu Evolution May Make Better Vaccines

November 21, 2014 9:37 am | News | Comments

An international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by ‘pre-empting’ the evolution of the influenza virus. Read more...           

Breakthrough Found to Help Manage Yellow Fever

November 21, 2014 9:24 am | News | Comments

Yellow fever is a disease that can result in symptoms ranging from fever to severe liver damage. Read more...                         

Beta-Blockers Show No Survival Benefits After Heart Attack

November 21, 2014 8:48 am | by Drug Discovery & Development Staff | Articles | Comments

Beta blockers offer no survival advantages to patients, post-heart attack, but they do improve survival among some heart failure patients. Read more...                                                          

New Approach for Treating ALS

November 20, 2014 1:45 pm | News | Comments

Researchers show that the brain’s machinery for pumping out toxins is ratcheted up in ALS patients. Read more...                         

Global Obesity Costs Hits $2 Trillion

November 20, 2014 12:35 pm | by Danica Kirka - Associated Press | News | Comments

The global cost of obesity has risen to to nearly as much as smoking or the combined aspect of armed violence, war and terrorism. Read more...                    

Virus Discovery Could Impact HIV Drug Research

November 20, 2014 12:23 pm | News | Comments

A research team has unlocked the structure of an unusual virus that lives in volcanic hot springs. Read more...                         

Promising One-Two Punch for Lung Cancer

November 20, 2014 10:19 am | News | Comments

Scientists at the Salk Institute have discovered a powerful one-two punch for countering a common genetic mutation that often leads to drug-resistant cancers. The dual-drug therapy–with analogs already in use for other diseases–doubled the survival rate of mice with lung cancer and halted cancer in pancreatic cells. Read more...

Early Statin Use May Give Long-Term Heart Benefits

November 20, 2014 10:06 am | by Marilynn Marchione, AP Chief Medical Writer - Associated Press | News | Comments

Taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward, and the benefits seem to grow over time, a landmark study finds. Doctors say it's the first evidence that early use of a statin can have a legacy effect, perhaps changing someone's odds of disease for good. Read more...

Mental Health Problems Increase Heart Disease Risk

November 20, 2014 9:42 am | by Cynthia Fox, Science Editor | Articles | Comments

People with mental health problems are “significantly” more likely to have stroke or heart disease, according to a study unveiled at a recent Canadian Cardiovascular Congress. Read more...

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