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Daily news and top headlines for drug research professionals

Strong Link Found Between Dementia, Common Anticholinergic Drugs

April 30, 2015 9:41 am | by Cynthia Fox, Science Editor | Articles | Comments

There is a strong and possibly irreversible link between Alzheimer’s disease and many commonly used medications for insomnia, allergies, and depression, according to a large recent JAMA Internal Medicine study. Read more...

Gene Variants Show Potential in Predicting Rheumatoid Arthritis Outcomes

April 29, 2015 4:29 pm | by University of Manchester | News | Comments

New cohort studies have shown that certain genetic variants are associated with higher or lower risks of increased disease severity. Read more...

Biomarkers Could Predict Response to Antipsychotic Treatment

April 29, 2015 4:22 pm | by King's College London | News | Comments

Only half of patients with psychosis respond to current medications and there is still a lack of knowledge surrounding the factors causing this lack of response. Read more...

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Valeant Raises Outlook after Completing Purchase of Salix

April 29, 2015 4:18 pm | by The Associated Press | News | Comments

Valeant's biggest businesses include dermatology, eye health, and neurology. Read more...

Flu Kills Millions of Birds, May Spread to Humans

April 29, 2015 1:41 pm | by Seth Augenstein, Digital Reporter | News | Comments

A strain of avian flu that has spread to chickens and turkeys in the Midwest and caused the death of millions of birds could make the jump to humans in time for next flu season, according to the U.S. Department of Agriculture and the Centers for Disease Control and Prevention. Read more..

Your Brain on Drugs: Functional Differences in Brain Communication in Cocaine Users

April 29, 2015 12:22 pm | by University of Texas Medical Branch | News | Comments

The brain function of people addicted to cocaine is different from that of people who are not addicted and often linked to highly impulsive behavior, according to a new scientific study. Read more...

Breaking Ground on Biologics

April 29, 2015 11:01 am | by Ryan Bushey, Associate Editor | Articles | Comments

One of the final sessions for the 2015 Experimental Biology Conference in Boston, Massachusetts was on biologics. Over the course of two and a half hours, a panel of scientists and experts discussed their research and where they see opportunity in this field. Read more...

3 Ways Technology is Changing the Face of Drug Discovery & Development

April 29, 2015 9:04 am | by Merrilyn Datta, PhD, President and General Manager, Definiens | Articles | Comments

While personalized medicine has been a goal for some time, there have been several obstacles. Although there has been an explosion in genomic data, the corresponding clinical utility for this data has been slow to be validated. Read more...

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World Malaria Day Brings Scourge into Spotlight

April 29, 2015 8:35 am | by Seth Augenstein, Digital Reporter | News | Comments

Malaria kills more than half a million people each year worldwide – and that’s after dramatic declines over the last decade. Read more...

Action Against Antibiotic Resistance Begins with Community

April 28, 2015 4:43 pm | by Wellcome Sanger Institute | News | Comments

To combat antibiotic resistance, scientists need to understand the evolution of bacteria and examine this alongside the characteristics of the populations they infect. Read more...

Novartis Announces Phase 3 Study of CLL Drug Met Primary Endpoint

April 28, 2015 4:34 pm | News | Comments

The safety profile observed in this trial is consistent with other trials of Arzerra and no new safety signals were observed. Read more....

U.N. Says It Will Try to Identify All Ebola Cases by June

April 28, 2015 4:21 pm | by Maria Cheng, AP Medical Writer | News | Comments

The World Health Organization said it aims to identify and isolate all new Ebola cases in West Africa by the end of May to stop the spread of the lethal virus before the rainy season. Read more...

Scientists Uncover Surprising New Details of Potential Alzheimer’s Treatment

April 28, 2015 1:26 pm | by The Scripps Research Institute | News | Comments

Taking a new approach, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered some surprising details of a group of compounds that have shown significant potential in stimulating the growth of brain cells and memory restoration in animal models that mimic Alzheimer’s disease. Read more...

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Two Treatments Yield Similar Results for Children After Cardiac Arrest

April 28, 2015 1:13 pm | by University of Michigan | News | Comments

A large-scale, multicenter study has shown that emergency body cooling does not improve survival rates or reduce brain injury in infants and children with out-of-hospital cardiac arrest more than normal temperature control. Read more...

Diabetes Drug Found in Freshwater is Potential Source of Intersex Fish

April 28, 2015 1:04 pm | by UWM | News | Comments

A medication commonly taken for Type II diabetes, which is being found in freshwater systems worldwide, has been shown to cause intersex in fish –male fish that produce eggs. Read more...

The Story of Biogen's Alzheimer's Drug, Aducanumab

April 28, 2015 10:28 am | by Cynthia Fox, Science Editor | Articles | Comments

The Biogen anti-amyloid antibody, aducanumab, took the 12th International Conference on Alzheimer’s and Parkinson’s Diseases in Nice, France by storm last month. The drug seemed able to significantly reduce amyloid in patients’ brains, while demonstrably slowing cognitive degeneration. It had analysts and scientists alike buzzing. Read more...

Molecular Health Gains European Patent for Novel Receptor

April 28, 2015 8:54 am | News | Comments

It addresses unmet need in treatment of millions of cancer patients. Read more...

Microneedle Patch for Measles Vaccination Could be Global Game Changer

April 28, 2015 8:45 am | by Georgia Institute of Technology | News | Comments

A new microneedle patch could make it easier to vaccinate people against measles and other vaccine-preventable diseases. Read more...

GSK Shingles Vaccine Demonstrates 97.2% Efficacy in Phase 3 Study

April 28, 2015 8:37 am | News | Comments

GlaxoSmithKline presented detailed data from a randomized phase 3 study of its investigational vaccine candidate for the prevention of shingles. Read more...

An End to Cancer Pain?

April 28, 2015 8:25 am | by University of Toronto | News | Comments

A new study has discovered the trigger behind the most severe forms of cancer pain. Read more...

Nerve Cells, Blood Vessels in Eye ‘Talk’ to Keep Healthy, Experts Say

April 27, 2015 4:35 pm | by Seth Augenstein, Digital Reporter | News | Comments

Nerve cells and blood vessels engage in a chemical discussion to keep healthy and avoid disease, according to a new study. The findings could lead to ways to prevent eyesight loss in diabetes and macular degeneration. Read more...

Simultaneous Quantitation of Metabolic Hormones

April 27, 2015 1:22 pm | by Tina Rose, Research Scientist; Qiang Xiao, Ph.D., R&D Manager, EMD Millipore Corporation | Articles | Comments

This article describes a new assay panel that helps overcome these challenges. The MILLIPLEX® MAP Human Metabolic Hormone Magnetic Bead Panel (EMD Millipore) enables the simultaneous quantitation of metabolism-relevant analytes, Read more...

Scientists Use Gene Editing to Correct Mutation in Cystic Fibrosis

April 27, 2015 12:25 pm | News | Comments

Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genetic disorder. Read more..

Indiana HIV Outbreak, Hepatitis C Epidemic Sparks CDC Alert

April 27, 2015 12:14 pm | by Jeni O'Malley, Associated Press | News | Comments

An Indiana county is experiencing nearly daily increases in new HIV infections tied to intravenous drug use, and health officials hope the situation prompts other states to closely track their hepatitis C and HIV rates to identify potential clusters of the diseases. Read more..

Innovation Gives Pregnant Women with Diabetes Round-the-Clock Glucose Control

April 27, 2015 9:02 am | by University of Leeds | News | Comments

Achieving better glucose control in pregnant women with diabetes by using continuous glucose monitoring may help them give birth to healthier children. Read more...

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