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Daily news and top headlines for drug research professionals

Drilling Down to Genetic Root of Prostate Tumor Development

April 1, 2015 1:26 pm | by Cancer Research UK | News | Comments

Scientists have revealed the root of prostate cancers in individual men, discovering that despite huge genetic variety between tumours they also share common gene faults - insight that could offer new treatment hopes, according to research published in Nature today. Read more..

Old Cancer Drug Could Have New Use in Fighting Cancer

April 1, 2015 1:15 pm | by University of Missouri | News | Comments

A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients with leukemia. Read more...

Experimental Cancer Drug Restores Memory in Mouse Model of Alzheimer’s

April 1, 2015 12:37 pm | by Yale University | News | Comments

Memory and as well as connections between brain cells were restored in mice with a model of Alzheimer’s given an experimental cancer drug, Yale School of Medicine researchers reported in the journal Annals of Neurology. Read more...

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Pill Manufacturing – A Second Revolution?

April 1, 2015 9:56 am | by Paul Roossin, Science Director Nanotronics Imaging | Articles | Comments

Pills have been used to deliver a measured medicinal dose for over three millennia. When the British artist, inventor, and watchmaker William Brockedon produced a compression machine for graphite to produce a better pencil lead, his invention was noticed by a savvy pharmaceutical company who hired him to retool the instrument to produce tablets. Read more...

Medieval Remedy Found to be Highly Effective Against MRSA

March 31, 2015 1:37 pm | by Stephanie Guzowski, Editor | News | Comments

British researchers recently found that a thousand-year-old Anglo-Saxon treatment for eye infections works as an antibiotic against MRSA. Read more...

Blood-Based Biomarkers Could Enable Accurate TB Tests for Diagnosis

March 31, 2015 11:48 am | by Emory University | News | Comments

Researchers have identified blood-based biomarkers in patients with active tuberculosis (ATB) that could lead to new blood-based diagnostics and tools for monitoring treatment response and cure. Read more...

Publication Bias, 'Spin,' Raise Questions About Anxiety Drugs

March 31, 2015 11:32 am | by Oregon State University | News | Comments

A new analysis reported in JAMA Psychiatry raises serious questions about the increasingly common use of second-generation antidepressant drugs to treat anxiety disorders. Read more...

BioDelivery Sciences’ Pain Treatment Fails Study

March 30, 2015 3:46 pm | by Stephanie Guzowski, Editor | News | Comments

BioDelivery Sciences International Inc. said on Monday its pain drug for diabetic neuropathy failed to meet the primary goal in a Phase 3 clinical trial. Shares fell nearly 30 percent. Read more...

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The Genomic Portrait of a Nation

March 29, 2015 4:01 pm | News | Comments

The studies present the most detailed portrait of a population yet assembled using the latest technology for reading DNA. Read more...

Integrative Approaches Key to Understanding Cancer and Developing Therapies

March 29, 2015 3:16 pm | by Moffitt Cancer Center | News | Comments

Researchers are using integrative approaches to study cancer by combining mathematical and computational modeling with experimental and clinical data. Read more...

MRI based on Sugar Molecule Can Tell Cancerous from Noncancerous Cells

March 27, 2015 2:06 pm | by Johns Hopkins University | News | Comments

Preliminary study in lab-grown cells raises possibility of cancer diagnosis without biopsies. Read more...

White House Releases Plan to Fight Antibiotic Resistance

March 27, 2015 12:58 pm | by Stephanie Guzowski, Editor | News | Comments

The White House has revealed today its comprehensive plan to tackle antibiotic resistance within the next five years, according to a copy of the 60-page report, which was reviewed by Reuters. Read more...

Researchers Create Method for Measuring Early Sign of Alzheimer's

March 27, 2015 10:36 am | by UCLA | News | Comments

After six years of painstaking research, a UCLA-led team has validated the first standardized protocol for measuring one of the earliest signs of Alzheimer’s disease — the atrophy of the part of the brain known as the hippocampus. Read more...

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Indiana Governor Overrides Law to Authorize Needle Exchange

March 27, 2015 10:32 am | by Rick Callahan, AP | News | Comments

Indiana Gov. Mike Pence overrode state law and his own anti-drug policies Thursday to authorize a short-term needle-exchange program designed to help contain HIV infections in a rural county where more than six dozen cases have been reported, all of them tied to intravenous drug use. Read more...

Roseroot Shows Promise as Potential Depression Treatment Option

March 27, 2015 10:27 am | by Penn University | News | Comments

Rhodiola rosea (R. rosea), or roseroot, may be a beneficial treatment option for major depressive disorder (MDD), according to results of a study in the journal Phytomedicine. Read more...

Cane Toads Potentially Lucrative Export in Cancer Fight

March 26, 2015 4:12 pm | by University of Queensland | News | Comments

Scientists are exploring how cane toad venom can be used to fight cancer. Read more...

HIV Replicates in Brain Earlier than Thought: Study

March 26, 2015 2:05 pm | by Stephanie Guzowski, Editor | News | Comments

A recent study, funded by the National Institutes of Health (NIH), highlights the importance of HIV screening and beginning antiretroviral therapy (ART) as early as possible. The analysis of cerebral spinal fluid (CSF), which illuminates brain chemical activity, showed that HIV can begin replicating in a patient’s brain as early as four months after infection. Read more...

New Autism-Causing Genetic Variant Identified

March 26, 2015 1:35 pm | by Johns Hopkins | News | Comments

Using a novel approach that homes in on rare families severely affected by autism, a Johns Hopkins-led team of researchers has identified a new genetic cause of the disease. Read more...

Common Bacteria on Verge of Becoming Antibiotic-Resistant Superbugs

March 26, 2015 1:29 pm | by Michael C. Purdy, Washington Univ. | News | Comments

Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis. Read more...

Men’s Heart Disease Partly Due to Low Estrogen

March 26, 2015 8:52 am | by Cynthia Fox, Science Writer | Articles | Comments

One reason men have more heart disease than women is the very fact that they are men, reports Harvard University endocrinologist Evelyn Yu, M.D., MS.c. Both men’s higher testosterone levels and their lower estrogen levels, play a role. Read more...

Ebola More Deadly for Young Children

March 26, 2015 8:37 am | by Sam Wong, Imperial College London | News | Comments

An international group of scientists analyzed data on Ebola cases in children under 16 during the current outbreak in Guinea, Liberia and Sierra Leone, comparing them to cases in adults. Read more...

GSK Gains Japanese Approval for COPD Therapy

March 26, 2015 8:25 am | News | Comments

Following this approval, it is expected that launch will take place in Japan in 2015. Read more...

Ugandan Official: Typhoid Sickens Hundreds in Capital

March 25, 2015 2:15 pm | by Rooney Muhumuza, Associated Press | News | Comments

An outbreak of typhoid fever has infected hundreds of people in the Ugandan capital, Kampala, and looks likely to spread as the rainy season gets under way. Read more...

Study Announces Durable Ebola Vaccine

March 25, 2015 2:10 pm | by Andrew Gould, University of Plymouth | News | Comments

A new study shows the durability of a novel CMV-based Ebola virus vaccine strategy that may eventually have the potential to reduce ebola virus infection in wild African ape species. Read more...

FDA Approves Anthrax Treatment

March 25, 2015 1:10 pm | by Stephanie Guzowski, Editor | News | Comments

The Food and Drug Administration (FDA) yesterday approved Emergent BioSolutions’ infusible drug Anthrasil for use in combination with antibiotics to treat inhalational anthrax, which happens when bacterial spores that carry anthrax are breathed in. Read more...

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