Drug Discovery & Development

Immunochemicals

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The Lead

Monoclonal Antibody

January 14, 2013 12:11 pm | Product Releases | Comments

Trevigen’s monoclonal ERCC1 antibody (4424-AMC-100) recognizes human ERCC1 and is suitable for Western blotting and immunocytochemistry.

Absorbance Reader

October 1, 2012 11:42 am | Product Releases | Comments

Berthold Technologies has released the Apollo 11, a dedicated absorbance reader. The instrument...

Scientists Find Promising Vaccine Targets for HCV

April 4, 2012 10:52 am | News | Comments

A team led by scientists at The Scripps Research Institute has found antibodies that can prevent...

Affinity Resin

March 27, 2012 10:55 am | Product Releases | Comments

GE Healthcare Life Sciences has added another affinity resin to its portfolio of technologies...

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DDD Update

Daily news and top headlines for drug research professionals

Protein Tag

May 22, 2012 11:51 am | Product Releases | Comments

Sandia Biotech's split-Green Fluorescent Protein technology allows researchers to analyze proteins and peptides with greater accuracy and fewer steps than current methods.

Immunoblotting Portfolio

April 17, 2012 11:57 am | Product Releases | Comments

The V3 Western Workflow from Bio-Rad Laboratories Inc. enables scientists to visualize protein separation, verify protein transfer, and confidently validate blot data via total protein normalization.

Ensuring Antibody Performance

April 12, 2012 3:55 pm | by Mike May, PhD, Contributing Editor | Articles | Comments

Given the variety of techniques for making antibodies, companies must ensure that scientists receive molecules that function as advertised.

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Improving the Immunoassay

March 19, 2012 2:25 pm | by Robert Durham, PhD, Field Application Specialist; Gyros AB, Uppsala, Sweden | Articles | Comments

The most commonly used immunoassay format continues to be the enzyme-linked immunosorbent assay, or ELISA. However, limitations associated with this technique become increasingly important.

Multiplex Immunoassay

March 12, 2012 10:11 am | Product Releases | Comments

The Bio-Plex Pro immunoassays from Bio-Rad Laboratories are magnetic bead–based multiplex immunoassays for human T-helper type 17 cytokines and cancer biomarkers.

Diagnostic Immunoassay

March 2, 2012 12:29 pm | Product Releases | Comments

Neurotune has launched its NTCAF ELISA immunoassay, an ELISA-based diagnostic assay for sarcopenia. The NTCAF ELISA test has initially been developed for research purposes to aid the development of a treatment for the condition.

Immunoassay Plate Guide

January 10, 2012 7:35 am | Product Releases | Comments

Thermo Fisher Scientific Inc.’s immunoassay plate guide comes as a searchable online resource, and in a tablet PC format.

Antibody Removal System

December 21, 2011 8:19 am | Product Releases | Comments

Based on G-Biosciences' Western ReProbe, this modified single component system is specifically formulated to dissociate and remove stubborn, high-affinity antibodies from membrane-bound proteins without destroying the antigenic-binding affinity.

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Spindle Antibodies

November 30, 2011 7:24 am | Product Releases | Comments

GeneTex has announced that they will be launching a line of antibodies against Hice1 and Hec1. Both of these targets are key players in spindle assembly.

Understanding Epigenetic Regulation

October 11, 2011 6:25 am | by John M. Rosenfeld, PhD, Manager, Chromatin Biology R&D; EMD Millipore, Temecula, Calif. | Articles | Comments

Epigenetic changes, such as DNA methylation, chromatin remodeling, and regulation of histone modifications, have been shown to play crucial roles in transcriptional regulation of most genes.

Fixing the Crisis in Antibiotics

June 3, 2011 11:47 am | by Ted Agres, Contributing Editor | Articles | Comments

Nature is winning the microbial battle against current antibiotics. Legislative and regulatory incentives may be needed to entice developers back into the fight.

Antibody Microarray

May 19, 2011 5:53 am | Product Releases | Comments

The QuantiPlasma Array, a monoclonal antibody microarray from Randox Pharma Services, is designed to assess the level of multiple proteins simultaneously in human plasma.

Isotyping ELISA Kit

May 19, 2011 5:43 am | Product Releases | Comments

A mouse monoclonal antibody (mAb) isotyping ELISA kit from Eagle Biosciences, Inc. uses a 96-well ELISA format for identification of both mouse immunoglobulin subclass and light chain.

Antibody Conjugates

May 6, 2011 8:28 am | Product Releases | Comments

BioLegend Inc. has released over 50 Brilliant Violet 421 antibody conjugates for use in flow cytometry and microscopy.

Tracking PTMs with Polyclonal Antibodies

April 12, 2011 7:22 am | by Mike May, PhD, Contributing Editor | Articles | Comments

As scientists use polyclonal antibodies more widely, their needs become more varied. Moreover, the reliability of catalogue polyclonals can fluctuate, so some researchers prefer an antibody designed and manufactured just for them.

Antibody Purification

April 5, 2011 8:16 am | Product Releases | Comments

GE Healthcare’s rProtein A GraviTrap, Protein G GraviTrap and rProtein A/Protein G GraviTrap, gravity-flow columns enable single-step, efficient manual purification of monoclonal and polyclonal antibodies from various species in milligram scale.

Optimizing the Antibody–Flow Cytometry Combination

January 11, 2011 10:33 am | by Mike May, Contributing Editor | Articles | Comments

Tracking specific components in complex samples plays a fundamental role in many aspects of modern drug discovery and development. To simultaneously measure multiple cell parameters, researchers can combine flow cytometry and multi-color antibody kits.

Aiming Antibodies at Cancer Research

June 8, 2010 10:30 am | by Mike May, PhD, Contributing Editor | Articles | Comments

In cancer research, antibodies provide an ever-expanding collection of tools that can be used in various ways, such as characterizing a drug target.

Anti-Bacteria Antibodies

May 3, 2010 6:59 am | Product Releases | Comments

BacTrace antibodies to infectious disease agents include Borrelia burgdorferi, Borrelia species, Legionella species and Helicobacter pylori.

Automated Cell-Based ELISA Procedures

May 3, 2010 6:42 am | Product Releases | Comments

Agilent Automation Solutions has configured its BioCel System that to allow laboratories to fully automate cell-based ELISA procedures thereby reducing the risk of human error, contamination, and time spent on tedious manual procedures.

ELISA Kit

April 27, 2010 8:06 am | Product Releases | Comments

Bioo Scientific introduced a new MaxDiscovery Apolipoprotein B ELISA Kit, a complete, two-step ELISA that analyzes the quantity of ApoB in tissues, serum, plasma or cultured cells for research purposes.

Antibody Preparation

March 30, 2010 7:49 am | Product Releases | Comments

The Beckman Coulter Antibody Cocktail Preparation Workstation automatically combines antibodies and staining dyes from individual vials into tubes or vials staged on the company’s Biomek NXp deck.

Prestige Antibodies

March 29, 2010 8:22 am | Product Releases | Comments

Sigma Life Science, the innovative biological products and services brand of Sigma-Aldrich, has added 2,200 new Prestige Antibodies powered by Atlas Antibodies to its industry-leading portfolio.

Monoclonal Antibodies

March 18, 2010 7:18 am | Product Releases | Comments

MorphoSys AG announced that its research and diagnostic antibody unit AbD Serotec has demonstrated significant progress using the HuCAL-based technology platform to generate custom-made monoclonal antibodies for research and diagnostic use.

ELISA Kit

April 30, 2009 8:06 am | Product Releases | Comments

PBL InterferonSource introduced VeriKine-HS Human Interferon-Beta Serum ELISA Kit, whihc is designed to provide IFN researchers the ability to accurately and reproducibly measure the level of IFN-ß in human serum or plasma samples.

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