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Combination Drug Targeting Opioid System May Help Relieve Treatment-resistant Depression

February 12, 2016 | by Massachusetts General Hospital | News | Comments

A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of serotonin and related monoamine neurotransmitters. Read more...

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Researchers Present Inner Workings of Ebola Vaccine Trial

February 12, 2016 10:20 am | by University of Florida | News | Comments

An experimental vaccine combined with an innovative way of vaccinating people has resulted in an estimated 100 percent efficacy of the vaccine against the Ebola virus in West Africa—and the approach could establish a new way of responding to outbreaks of emerging pathogens, including the Zika virus. Read more...

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Gene Signature Could Lead to a New Way of Diagnosing Lyme

February 12, 2016 9:59 am | by University of California, San Francisco | News | Comments

Researchers at UC San Francisco and Johns Hopkins may have found a new way to diagnose Lyme disease, based on a distinctive gene "signature" they discovered in white blood cells of patients infected with the tick-borne bacteria. Read more...

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Study: Neanderthal DNA May Influence Modern Depression Risk

February 12, 2016 9:54 am | by Malcom Ritter, AP Science Writer | News | Comments

A new study says a person's risk of becoming depressed or hooked on smoking may be influenced by DNA inherited from Neanderthals. Read more...

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UK Competition Authorities Fine GSK $54.5M

February 12, 2016 8:58 am | by Danica Kirka, Associated Press | News | Comments

The fine leveled Friday is the largest since the Competition and Markets Authority's inception in 2014. Read more...

New Biomarker Assay Offers Hope for Parkinson's Patients

February 12, 2016 8:55 am | by CORDIS | News | Comments

Parkinson’s disease is one of the most prevalent neurodegenerative disorders. Read more...

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Superbug Review Says More Vaccines Needed to Reduce Antibiotic Use

February 12, 2016 8:48 am | by Kate Kelland, Reuters | News | Comments

More use of vaccines would reduce the need to use antibiotics and help fight the rise of drug-resistant superbug infections. Read more...

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EMA Accepts Application for Biosimilar Pegfilgrastim

February 12, 2016 8:45 am | News | Comments

Sandoz is committed to increasing patient access to high-quality, life-enhancing biosimilars. Read more...

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Brazil and U.S. University Reach Deal on Zika Vaccine

February 12, 2016 8:38 am | by Joshua Goodman, Associated Press | News | Comments

Brazil has signed an agreement with the University of Texas Medical Branch to develop a vaccine against the Zika virus, adding the goal is for the vaccine to be ready for clinical testing within 12 months. Read more...

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Risk Mitigation Pivotal to Starting Clinical Trials

February 11, 2016 11:02 am | by Craig Morgan, Brand Development Director, goBalto Inc. | Articles | Comments

While risk management efforts in drug development have focused mostly on post-marketing drug safety, the clinical trials process has its own mix of potential risks just waiting to derail a company’s high-dollar development programs. These risks include patient enrollment issues, site staffing shortages, logistical problems with drug supplies, and regulatory delays. Read more...

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Researchers Discover Underlying Cause of Myeloma

February 11, 2016 10:59 am | by Yale University | News | Comments

Yale Cancer Center researchers have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published Feb. 10 in the New England Journal of Medicine, could fundamentally change the way this cancer and others are treated. Read more...

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Dementia Risk Varies Significantly Among Racial And Ethnic Groups, Study Finds

February 11, 2016 10:50 am | by UCSF | News | Comments

In the largest and longest study thus far of ethnic disparities in dementia risk, researchers compared six ethnic and racial groups within the same geographic population and found significant variation in dementia incidence among them. The results are published online in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. Read more..

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Researchers Offer New Approach to Treating Cocaine Addiction

February 11, 2016 10:38 am | by University of Pennsylvania | News | Comments

In the ongoing fight against drug addiction, researchers from the University of Pennsylvania's School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine dependence. Read more...

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Scientists Find Leukemia's Surroundings Key to Its Growth

February 11, 2016 10:19 am | by University of Texas at Austin | News | Comments

Researchers at The University of Texas at Austin have discovered that a type of cancer found primarily in children can grow only when signaled to do so by other nearby cells that are noncancerous. Read more...

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Novartis Heart Failure Drug Gets Performance-based Pricing

February 11, 2016 10:16 am | by Ryan Bushey, Associate Editor | News | Comments

Novartis announced on Monday it would install a health outcome-oriented pricing strategy for heart failure drug Entresto supported by health insurers Cigna and Aetna. Read more...

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Study Finds Zika Virus in Brain, A Clue in Outbreak

February 11, 2016 8:53 am | by Lauren Neergaard, AP Medical Writer | News | Comments

New details about the possible effects of the Zika virus on the fetal brain emerged Wednesday. Read more...

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